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J Am Chem Soc. 2021 Jul 14;143(27):10389-10402. doi: 10.1021/jacs.1c04825. Epub 2021 Jul 02.

Mutanobactin D from the Human Microbiome: Total Synthesis, Configurational Assignment, and Biological Evaluation.

Journal of the American Chemical Society

Felix Pultar, Moritz E Hansen, Susanne Wolfrum, Lennard Böselt, Ricardo Fróis-Martins, Susanne Bloch, Alberto G Kravina, Deren Pehlivanoglu, Christina Schäffer, Salomé LeibundGut-Landmann, Sereina Riniker, Erick M Carreira

Affiliations

  1. Laboratorium für Organische Chemie, ETH Zürich, D-CHAB, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland.
  2. Laboratorium für Physikalische Chemie, ETH Zürich, D-CHAB, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.
  3. Section of Immunology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 266a, 8057 Zürich, Switzerland.
  4. Institute of Experimental Immunology, University of Zürich, Winterthurerstrasse 190, 8057 Zürich, Switzerland.
  5. Department of NanoBiotechnology, NanoGlycobiology Unit, Universität für Bodenkultur Wien, Muthgasse 11, 1190 Vienna, Austria.

PMID: 34212720 DOI: 10.1021/jacs.1c04825

Abstract

Mutanobactin D is a non-ribosomal, cyclic peptide isolated from

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