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Yan D, Gudjonsson JE, Le S, et al. New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. J Invest Dermatol. 2021;141(9):2112-2122.e3doi: 10.1016/j.jid.2021.02.764.
Yan, D., Gudjonsson, J. E., Le, S., Maverakis, E., Plazyo, O., Ritchlin, C., Scher, J. U., Singh, R., Ward, N. L., Bell, S., & Liao, W. (2021). New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. The Journal of investigative dermatology, 141(9), 2112-2122.e3. https://doi.org/10.1016/j.jid.2021.02.764
Yan, Di, et al. "New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine." The Journal of investigative dermatology vol. 141,9 (2021): 2112-2122.e3. doi: https://doi.org/10.1016/j.jid.2021.02.764
Yan D, Gudjonsson JE, Le S, Maverakis E, Plazyo O, Ritchlin C, Scher JU, Singh R, Ward NL, Bell S, Liao W. New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. J Invest Dermatol. 2021 Sep;141(9):2112-2122.e3. doi: 10.1016/j.jid.2021.02.764. Epub 2021 Jul 22. PMID: 34303522; PMCID: PMC8384663.
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J Invest Dermatol. 2021 Sep;141(9):2112-2122.e3. doi: 10.1016/j.jid.2021.02.764. Epub 2021 Jul 22.

New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine.

The Journal of investigative dermatology

Di Yan, Johann E Gudjonsson, Stephanie Le, Emanual Maverakis, Olesya Plazyo, Christopher Ritchlin, Jose U Scher, Roopesh Singh, Nicole L Ward, Stacie Bell, Wilson Liao

Affiliations

  1. Ronald O. Perelman Department of Dermatology, NYU Langone Health, New York, New York, USA.
  2. Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
  3. Department of Dermatology, University of California, Davis, Sacramento, California, USA.
  4. Center for Musculoskeletal Research, Division of Allergy, Immunology and Rheumatology, University of Rochester School of Medicine & Dentistry, Rochester, New York, USA.
  5. Department of Medicine, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA.
  6. Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
  7. Department of Nutrition, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA; Department of Dermatology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
  8. National Psoriasis Foundation, Portland, Oregon, USA.
  9. UCSF Department of Dermatology, University of California San Francisco, San Francisco, California, USA. Electronic address: [email protected].

PMID: 34303522 PMCID: PMC8384663 DOI: 10.1016/j.jid.2021.02.764

Abstract

Psoriasis is a chronic inflammatory condition characterized by systemic immune dysregulation. Over the past several years, advances in genetics, microbiology, immunology, and mouse models have revealed the complex interplay between the heritable and microenvironmental factors that drive the development of psoriatic inflammation. In the first of this two-part review series, the authors will discuss the newest insights into the pathogenesis of psoriatic disease and highlight how the evolution of these scientific fields has paved the way for a more personalized approach to psoriatic disease treatment.

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

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