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Treatment of melanoma in-transit metastases with combination intralesional interleukin-2, topical imiquimod, and tretinoin 0.1% cream.

JAAD case reports

Leventhal JS, Odell ID, Imaeda S, Maverakis E, King BA.
PMID: 27051847
JAAD Case Rep. 2016 Mar 04;2(2):114-6. doi: 10.1016/j.jdcr.2016.01.004. eCollection 2016 Mar.

No abstract available.

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Leventhal JS, Odell ID, Imaeda S, et al. Treatment of melanoma in-transit metastases with combination intralesional interleukin-2, topical imiquimod, and tretinoin 0.1% cream. JAAD Case Rep. 2016;2(2):114-6doi: 10.1016/j.jdcr.2016.01.004.
Leventhal, J. S., Odell, I. D., Imaeda, S., Maverakis, E., & King, B. A. (2016). Treatment of melanoma in-transit metastases with combination intralesional interleukin-2, topical imiquimod, and tretinoin 0.1% cream. JAAD case reports, 2(2), 114-6. https://doi.org/10.1016/j.jdcr.2016.01.004
Leventhal, Jonathan S, et al. "Treatment of melanoma in-transit metastases with combination intralesional interleukin-2, topical imiquimod, and tretinoin 0.1% cream." JAAD case reports vol. 2,2 (2016): 114-6. doi: https://doi.org/10.1016/j.jdcr.2016.01.004
Leventhal JS, Odell ID, Imaeda S, Maverakis E, King BA. Treatment of melanoma in-transit metastases with combination intralesional interleukin-2, topical imiquimod, and tretinoin 0.1% cream. JAAD Case Rep. 2016 Mar 04;2(2):114-6. doi: 10.1016/j.jdcr.2016.01.004. eCollection 2016 Mar. PMID: 27051847; PMCID: PMC4810288.
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Cells within a cell: Insights into cellular architecture and polarization from the organization of the early fly embryo.

Communicative & integrative biology

Mavrakis M, Rikhy R, Lippincott-Schwartz J.
PMID: 19721875
Commun Integr Biol. 2009 Jul;2(4):313-4. doi: 10.4161/cib.2.4.8240.

Drosophila embryogenesis begins with 13 rapid nuclear divisions within a common cytoplasm. These divisions produce approximately 6,000 nuclei that, during the next division cycle, become encased in plasma membrane (PM) and generate the primary embryonic epithelium in the process...

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Mavrakis M, Rikhy R, Lippincott-Schwartz J. Cells within a cell: Insights into cellular architecture and polarization from the organization of the early fly embryo. Commun Integr Biol. 2009;2(4):313-4doi: 10.4161/cib.2.4.8240.
Mavrakis, M., Rikhy, R., & Lippincott-Schwartz, J. (2009). Cells within a cell: Insights into cellular architecture and polarization from the organization of the early fly embryo. Communicative & integrative biology, 2(4), 313-4. https://doi.org/10.4161/cib.2.4.8240
Mavrakis, Manos, et al. "Cells within a cell: Insights into cellular architecture and polarization from the organization of the early fly embryo." Communicative & integrative biology vol. 2,4 (2009): 313-4. doi: https://doi.org/10.4161/cib.2.4.8240
Mavrakis M, Rikhy R, Lippincott-Schwartz J. Cells within a cell: Insights into cellular architecture and polarization from the organization of the early fly embryo. Commun Integr Biol. 2009 Jul;2(4):313-4. doi: 10.4161/cib.2.4.8240. PMID: 19721875; PMCID: PMC2734032.
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Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model.

ISRN dermatology

Martinez SR, Shah DR, Yang AD, Canter RJ, Maverakis E.
PMID: 23378929
ISRN Dermatol. 2013;2013:315609. doi: 10.1155/2013/315609. Epub 2013 Jan 10.

Background. Sentinel lymph node biopsy (SLNB) for thick cutaneous melanoma is supported by national guidelines. We report on factors associated with the use and underuse of SLNB for thick primary cutaneous melanoma. Methods. The Surveillance, Epidemiology, and End Results...

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Martinez SR, Shah DR, Yang AD, et al. Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model. ISRN Dermatol. 2013;2013:315609doi: 10.1155/2013/315609.
Martinez, S. R., Shah, D. R., Yang, A. D., Canter, R. J., & Maverakis, E. (2013). Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model. ISRN dermatology, 2013315609. https://doi.org/10.1155/2013/315609
Martinez, Steve R, et al. "Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model." ISRN dermatology vol. 2013 (2013): 315609. doi: https://doi.org/10.1155/2013/315609
Martinez SR, Shah DR, Yang AD, Canter RJ, Maverakis E. Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model. ISRN Dermatol. 2013;2013:315609. doi: 10.1155/2013/315609. Epub 2013 Jan 10. PMID: 23378929; PMCID: PMC3556403.
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Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension.

Pulmonary circulation

Duong HT, Comhair SA, Aldred MA, Mavrakis L, Savasky BM, Erzurum SC, Asosingh K.
PMID: 22530103
Pulm Circ. 2011 Oct-Dec;1(4):475-86. doi: 10.4103/2045-8932.93547.

Proliferative pulmonary vascular remodeling is the pathologic hallmark of pulmonary arterial hypertension (PAH) that ultimately leads to right heart failure and death. Highly proliferative endothelial cells known as endothelial colony-forming cells (ECFC) participate in vascular homeostasis in health as...

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Duong HT, Comhair SA, Aldred MA, et al. Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension. Pulm Circ. 2011;1(4):475-86doi: 10.4103/2045-8932.93547.
Duong, H. T., Comhair, S. A., Aldred, M. A., Mavrakis, L., Savasky, B. M., Erzurum, S. C., & Asosingh, K. (2011). Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension. Pulmonary circulation, 1(4), 475-86. https://doi.org/10.4103/2045-8932.93547
Duong, Heng T, et al. "Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension." Pulmonary circulation vol. 1,4 (2011): 475-86. doi: https://doi.org/10.4103/2045-8932.93547
Duong HT, Comhair SA, Aldred MA, Mavrakis L, Savasky BM, Erzurum SC, Asosingh K. Pulmonary artery endothelium resident endothelial colony-forming cells in pulmonary arterial hypertension. Pulm Circ. 2011 Oct-Dec;1(4):475-86. doi: 10.4103/2045-8932.93547. PMID: 22530103; PMCID: PMC3329078.
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Phytochemicals and Naturally Derived Substances for Wound Healing.

Advances in wound care

Sivamani RK, Ma BR, Wehrli LN, Maverakis E.
PMID: 24527308
Adv Wound Care (New Rochelle). 2012 Oct;1(5):213-217. doi: 10.1089/wound.2011.0330.

BACKGROUND: Complementary and alternative medicines (CAMs) are widely used by the general public. Natural products including plant-derived extracts (phytochemicals) and naturally derived substances, such as honey, are an important component of CAM. Here, we review the evidence for their...

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Sivamani RK, Ma BR, Wehrli LN, et al. Phytochemicals and Naturally Derived Substances for Wound Healing. Adv Wound Care (New Rochelle). 2012;1(5):213-217doi: 10.1089/wound.2011.0330.
Sivamani, R. K., Ma, B. R., Wehrli, L. N., & Maverakis, E. (2012). Phytochemicals and Naturally Derived Substances for Wound Healing. Advances in wound care, 1(5), 213-217. https://doi.org/10.1089/wound.2011.0330
Sivamani, Raja K, et al. "Phytochemicals and Naturally Derived Substances for Wound Healing." Advances in wound care vol. 1,5 (2012): 213-217. doi: https://doi.org/10.1089/wound.2011.0330
Sivamani RK, Ma BR, Wehrli LN, Maverakis E. Phytochemicals and Naturally Derived Substances for Wound Healing. Adv Wound Care (New Rochelle). 2012 Oct;1(5):213-217. doi: 10.1089/wound.2011.0330. PMID: 24527308; PMCID: PMC3839002.
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Septin-microtubule association via a motif unique to the isoform 1 of septin 9 tunes stress fibers.

Journal of cell science

Kuzmić M, Linares GC, Fialová JL, Iv F, Salaün D, Llewellyn A, Gomes M, Belhabib M, Liu Y, Asano K, Rodrigues M, Isnardon D, Tachibana T, Koenderink GH, Badache A, Mavrakis M, Verdier-Pinard P.
PMID: 34854883
J Cell Sci. 2021 Dec 02; doi: 10.1242/jcs.258850. Epub 2021 Dec 02.

Septins, a family of GTP-binding proteins assembling into higher order structures, interface with the membrane, actin filaments and microtubules, which positions them as important regulators of cytoarchitecture. Septin 9 (SEPT9), which is frequently overexpressed in tumors and mutated in...

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Kuzmić M, Linares GC, Fialová JL, et al. Septin-microtubule association via a motif unique to the isoform 1 of septin 9 tunes stress fibers. J Cell Sci. 2021;doi: 10.1242/jcs.258850.
Kuzmić, M., Linares, G. C., Fialová, J. L., Iv, F., Salaün, D., Llewellyn, A., Gomes, M., Belhabib, M., Liu, Y., Asano, K., Rodrigues, M., Isnardon, D., Tachibana, T., Koenderink, G. H., Badache, A., Mavrakis, M., & Verdier-Pinard, P. (2021). Septin-microtubule association via a motif unique to the isoform 1 of septin 9 tunes stress fibers. Journal of cell science, . https://doi.org/10.1242/jcs.258850
Kuzmić, Mira, et al. "Septin-microtubule association via a motif unique to the isoform 1 of septin 9 tunes stress fibers." Journal of cell science vol. (2021). doi: https://doi.org/10.1242/jcs.258850
Kuzmić M, Linares GC, Fialová JL, Iv F, Salaün D, Llewellyn A, Gomes M, Belhabib M, Liu Y, Asano K, Rodrigues M, Isnardon D, Tachibana T, Koenderink GH, Badache A, Mavrakis M, Verdier-Pinard P. Septin-microtubule association via a motif unique to the isoform 1 of septin 9 tunes stress fibers. J Cell Sci. 2021 Dec 02; doi: 10.1242/jcs.258850. Epub 2021 Dec 02. PMID: 34854883.
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New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine.

The Journal of investigative dermatology

Yan D, Gudjonsson JE, Le S, Maverakis E, Plazyo O, Ritchlin C, Scher JU, Singh R, Ward NL, Bell S, Liao W.
PMID: 34303522
J Invest Dermatol. 2021 Sep;141(9):2112-2122.e3. doi: 10.1016/j.jid.2021.02.764. Epub 2021 Jul 22.

Psoriasis is a chronic inflammatory condition characterized by systemic immune dysregulation. Over the past several years, advances in genetics, microbiology, immunology, and mouse models have revealed the complex interplay between the heritable and microenvironmental factors that drive the development...

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Yan D, Gudjonsson JE, Le S, et al. New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. J Invest Dermatol. 2021;141(9):2112-2122.e3doi: 10.1016/j.jid.2021.02.764.
Yan, D., Gudjonsson, J. E., Le, S., Maverakis, E., Plazyo, O., Ritchlin, C., Scher, J. U., Singh, R., Ward, N. L., Bell, S., & Liao, W. (2021). New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. The Journal of investigative dermatology, 141(9), 2112-2122.e3. https://doi.org/10.1016/j.jid.2021.02.764
Yan, Di, et al. "New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine." The Journal of investigative dermatology vol. 141,9 (2021): 2112-2122.e3. doi: https://doi.org/10.1016/j.jid.2021.02.764
Yan D, Gudjonsson JE, Le S, Maverakis E, Plazyo O, Ritchlin C, Scher JU, Singh R, Ward NL, Bell S, Liao W. New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. J Invest Dermatol. 2021 Sep;141(9):2112-2122.e3. doi: 10.1016/j.jid.2021.02.764. Epub 2021 Jul 22. PMID: 34303522; PMCID: PMC8384663.
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Porphyria cutanea tarda presenting as a lichenoid eruption.

Photodermatology, photoimmunology & photomedicine

Toussi A, Le ST, Merleev AA, Marusina AI, Luxardi G, Downing L, Tran M, Kiuru MH, Maverakis E.
PMID: 33305390
Photodermatol Photoimmunol Photomed. 2021 May;37(3):233-235. doi: 10.1111/phpp.12640. Epub 2020 Dec 22.

No abstract available.

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Toussi A, Le ST, Merleev AA, et al. Porphyria cutanea tarda presenting as a lichenoid eruption. Photodermatol Photoimmunol Photomed. 2020;37(3):233-235doi: 10.1111/phpp.12640.
Toussi, A., Le, S. T., Merleev, A. A., Marusina, A. I., Luxardi, G., Downing, L., Tran, M., Kiuru, M. H., & Maverakis, E. (2021). Porphyria cutanea tarda presenting as a lichenoid eruption. Photodermatology, photoimmunology & photomedicine, 37(3), 233-235. https://doi.org/10.1111/phpp.12640
Toussi, Atrin, et al. "Porphyria cutanea tarda presenting as a lichenoid eruption." Photodermatology, photoimmunology & photomedicine vol. 37,3 (2021): 233-235. doi: https://doi.org/10.1111/phpp.12640
Toussi A, Le ST, Merleev AA, Marusina AI, Luxardi G, Downing L, Tran M, Kiuru MH, Maverakis E. Porphyria cutanea tarda presenting as a lichenoid eruption. Photodermatol Photoimmunol Photomed. 2021 May;37(3):233-235. doi: 10.1111/phpp.12640. Epub 2020 Dec 22. PMID: 33305390.
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The Conundrum of Poor Ovarian Response: From Diagnosis to Treatment.

Diagnostics (Basel, Switzerland)

Giannelou P, Simopoulou M, Grigoriadis S, Makrakis E, Kontogeorgi A, Pantou A, Galatis D, Kalampokas T, Bakas P, Bolaris S, Pantos K, Sfakianoudis K.
PMID: 32932955
Diagnostics (Basel). 2020 Sep 11;10(9). doi: 10.3390/diagnostics10090687.

Despite recent striking advances in assisted reproductive technology (ART), poor ovarian response (POR) diagnosis and treatment is still considered challenging. Poor responders constitute a heterogeneous cohort with the common denominator of under-responding to controlled ovarian stimulation. Inevitably, respective success...

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Giannelou P, Simopoulou M, Grigoriadis S, et al. The Conundrum of Poor Ovarian Response: From Diagnosis to Treatment. Diagnostics (Basel). 2020;10(9)doi: 10.3390/diagnostics10090687.
Giannelou, P., Simopoulou, M., Grigoriadis, S., Makrakis, E., Kontogeorgi, A., Pantou, A., Galatis, D., Kalampokas, T., Bakas, P., Bolaris, S., Pantos, K., & Sfakianoudis, K. (2020). The Conundrum of Poor Ovarian Response: From Diagnosis to Treatment. Diagnostics (Basel, Switzerland), 10(9), . https://doi.org/10.3390/diagnostics10090687
Giannelou, Polina, et al. "The Conundrum of Poor Ovarian Response: From Diagnosis to Treatment." Diagnostics (Basel, Switzerland) vol. 10,9 (2020). doi: https://doi.org/10.3390/diagnostics10090687
Giannelou P, Simopoulou M, Grigoriadis S, Makrakis E, Kontogeorgi A, Pantou A, Galatis D, Kalampokas T, Bakas P, Bolaris S, Pantos K, Sfakianoudis K. The Conundrum of Poor Ovarian Response: From Diagnosis to Treatment. Diagnostics (Basel). 2020 Sep 11;10(9). doi: 10.3390/diagnostics10090687. PMID: 32932955; PMCID: PMC7555981.
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"Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis.

Cellular & molecular immunology

Uppala R, Tsoi LC, Harms PW, Wang B, Billi AC, Maverakis E, Michelle Kahlenberg J, Ward NL, Gudjonsson JE.
PMID: 32814870
Cell Mol Immunol. 2021 Feb;18(2):307-317. doi: 10.1038/s41423-020-0519-3. Epub 2020 Aug 19.

Psoriasis is a chronic inflammatory skin condition that has a fairly wide range of clinical presentations. Plaque psoriasis, which is the most common manifestation of psoriasis, is located on one end of the spectrum, dominated by adaptive immune responses,...

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Uppala R, Tsoi LC, Harms PW, et al. "Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis. Cell Mol Immunol. 2020;18(2):307-317doi: 10.1038/s41423-020-0519-3.
Uppala, R., Tsoi, L. C., Harms, P. W., Wang, B., Billi, A. C., Maverakis, E., Michelle Kahlenberg, J., Ward, N. L., & Gudjonsson, J. E. (2021). "Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis. Cellular & molecular immunology, 18(2), 307-317. https://doi.org/10.1038/s41423-020-0519-3
Uppala, Ranjitha, et al. ""Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis." Cellular & molecular immunology vol. 18,2 (2021): 307-317. doi: https://doi.org/10.1038/s41423-020-0519-3
Uppala R, Tsoi LC, Harms PW, Wang B, Billi AC, Maverakis E, Michelle Kahlenberg J, Ward NL, Gudjonsson JE. "Autoinflammatory psoriasis"-genetics and biology of pustular psoriasis. Cell Mol Immunol. 2021 Feb;18(2):307-317. doi: 10.1038/s41423-020-0519-3. Epub 2020 Aug 19. PMID: 32814870; PMCID: PMC8027616.
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Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts.

The Journal of experimental medicine

Kerdidani D, Aerakis E, Verrou KM, Angelidis I, Douka K, Maniou MA, Stamoulis P, Goudevenou K, Prados A, Tzaferis C, Ntafis V, Vamvakaris I, Kaniaris E, Vachlas K, Sepsas E, Koutsopoulos A, Potaris K, Tsoumakidou M.
PMID: 35029648
J Exp Med. 2022 Feb 07;219(2). doi: 10.1084/jem.20210815. Epub 2022 Jan 14.

A key unknown of the functional space in tumor immunity is whether CD4 T cells depend on intratumoral MHCII cancer antigen recognition. MHCII-expressing, antigen-presenting cancer-associated fibroblasts (apCAFs) have been found in breast and pancreatic tumors and are considered to...

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Kerdidani D, Aerakis E, Verrou KM, et al. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. J Exp Med. 2022;219(2)doi: 10.1084/jem.20210815.
Kerdidani, D., Aerakis, E., Verrou, K. M., Angelidis, I., Douka, K., Maniou, M. A., Stamoulis, P., Goudevenou, K., Prados, A., Tzaferis, C., Ntafis, V., Vamvakaris, I., Kaniaris, E., Vachlas, K., Sepsas, E., Koutsopoulos, A., Potaris, K., & Tsoumakidou, M. (2022). Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. The Journal of experimental medicine, 219(2), . https://doi.org/10.1084/jem.20210815
Kerdidani, Dimitra, et al. "Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts." The Journal of experimental medicine vol. 219,2 (2022). doi: https://doi.org/10.1084/jem.20210815
Kerdidani D, Aerakis E, Verrou KM, Angelidis I, Douka K, Maniou MA, Stamoulis P, Goudevenou K, Prados A, Tzaferis C, Ntafis V, Vamvakaris I, Kaniaris E, Vachlas K, Sepsas E, Koutsopoulos A, Potaris K, Tsoumakidou M. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. J Exp Med. 2022 Feb 07;219(2). doi: 10.1084/jem.20210815. Epub 2022 Jan 14. PMID: 35029648.
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Long-term prognostic value of myocardin expression levels in non-ischemic dilated cardiomyopathy.

Heart and vessels

Marketou ME, Kontaraki J, Patrianakos A, Kanoupakis E, Plevritaki A, Mavrakis H, Kallergis E, Koutalas E, Anastasiou I, Chlouverakis G, Parthenakis F.
PMID: 33983455
Heart Vessels. 2021 Dec;36(12):1841-1847. doi: 10.1007/s00380-021-01869-0. Epub 2021 May 13.

The mortality of patients with non-ischemic dilated cardiomyopathy (NIDCM) remains substantial. We evaluated gene expression levels of myocardin, an early cardiac gene, in the peripheral blood cells of NIDCM patients as a prognostic biomarker in their long-term outcome and...

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Marketou ME, Kontaraki J, Patrianakos A, et al. Long-term prognostic value of myocardin expression levels in non-ischemic dilated cardiomyopathy. Heart Vessels. 2021;36(12):1841-1847doi: 10.1007/s00380-021-01869-0.
Marketou, M. E., Kontaraki, J., Patrianakos, A., Kanoupakis, E., Plevritaki, A., Mavrakis, H., Kallergis, E., Koutalas, E., Anastasiou, I., Chlouverakis, G., & Parthenakis, F. (2021). Long-term prognostic value of myocardin expression levels in non-ischemic dilated cardiomyopathy. Heart and vessels, 36(12), 1841-1847. https://doi.org/10.1007/s00380-021-01869-0
Marketou, Maria E, et al. "Long-term prognostic value of myocardin expression levels in non-ischemic dilated cardiomyopathy." Heart and vessels vol. 36,12 (2021): 1841-1847. doi: https://doi.org/10.1007/s00380-021-01869-0
Marketou ME, Kontaraki J, Patrianakos A, Kanoupakis E, Plevritaki A, Mavrakis H, Kallergis E, Koutalas E, Anastasiou I, Chlouverakis G, Parthenakis F. Long-term prognostic value of myocardin expression levels in non-ischemic dilated cardiomyopathy. Heart Vessels. 2021 Dec;36(12):1841-1847. doi: 10.1007/s00380-021-01869-0. Epub 2021 May 13. PMID: 33983455.
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