Display options
Cite
Xu S, Shi X, Chu C, et al. A TME-activated in situ nanogenerator for magnetic resonance/fluorescence/photoacoustic imaging. Methods Enzymol. 2021;657:145-156doi: 10.1016/bs.mie.2021.06.029.
Xu, S., Shi, X., Chu, C., & Liu, G. (2021). A TME-activated in situ nanogenerator for magnetic resonance/fluorescence/photoacoustic imaging. Methods in enzymology, 657145-156. https://doi.org/10.1016/bs.mie.2021.06.029
Xu, Shuyu, et al. "A TME-activated in situ nanogenerator for magnetic resonance/fluorescence/photoacoustic imaging." Methods in enzymology vol. 657 (2021): 145-156. doi: https://doi.org/10.1016/bs.mie.2021.06.029
Xu S, Shi X, Chu C, Liu G. A TME-activated in situ nanogenerator for magnetic resonance/fluorescence/photoacoustic imaging. Methods Enzymol. 2021;657:145-156. doi: 10.1016/bs.mie.2021.06.029. Epub 2021 Jul 13. PMID: 34353485.
Copy Download .nbib Format: NLM
Share it on

Methods Enzymol. 2021;657:145-156. doi: 10.1016/bs.mie.2021.06.029. Epub 2021 Jul 13.

A TME-activated in situ nanogenerator for magnetic resonance/fluorescence/photoacoustic imaging.

Methods in enzymology

Shuyu Xu, Xiaoxiao Shi, Chengchao Chu, Gang Liu

Affiliations

  1. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
  2. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, China; Amoy Hopeful Biotechnology Co., Ltd., Xiamen, China. Electronic address: [email protected].
  3. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Biology, School of Life Sciences, Xiamen University, Xiamen, China. Electronic address: [email protected].

PMID: 34353485 DOI: 10.1016/bs.mie.2021.06.029

Abstract

With the rapid development of biomedical imaging, non-invasive imaging method particularly has been widely used in clinical diagnosis. Different imaging methods have their own advantages, such as higher resolution of optical imaging, deeper penetration of acoustic imaging, high resolution photoacoustic imaging (PAI), and multi-parameter guidance of magnetic resonance imaging (MRI). Recent years, multimodal MRI, fluorescence imaging, PAI and others have been verified to play an important role in the field of molecular imaging and provided detail information for accurate in vivo diagnosis. Therefore, the design of multimodal probe that can integrate the above advantages to carry out combined imaging will be more accurate to assist diagnosis and treatment. While tumor microenvironment (TME) is highly critical in validating and optimizing current therapeutic strategies. Herein, we highlight the TME-triggered supramolecular system as an in situ nano-generator for multimodal imaging-guided treatment. The experimental protocols on the PAI/fluorescence imaging/MRI-based diagnosis are described in this chapter.

Copyright © 2021 Elsevier Inc. All rights reserved.

Keywords: Fluorescence imaging; In situ nano-generator; Magnetic resonance imaging; Molecular imaging; Multimodal imaging; Nanotheranostics; Photoacoustic imaging; Supramolecular assembly; Tumor microenvironment

MeSH terms

Publication Types