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Genizi J, Hendler-Sade A, Segal I, et al. Outcomes of Migraine and Tension-Type Headache in Children and Adolescents. Life (Basel). 2021;11(7)doi: 10.3390/life11070684.
Genizi, J., Hendler-Sade, A., Segal, I., Bamberger, E., Srugo, I., & Kerem, N. C. (2021). Outcomes of Migraine and Tension-Type Headache in Children and Adolescents. Life (Basel, Switzerland), 11(7), . https://doi.org/10.3390/life11070684
Genizi, Jacob, et al. "Outcomes of Migraine and Tension-Type Headache in Children and Adolescents." Life (Basel, Switzerland) vol. 11,7 (2021). doi: https://doi.org/10.3390/life11070684
Genizi J, Hendler-Sade A, Segal I, Bamberger E, Srugo I, Kerem NC. Outcomes of Migraine and Tension-Type Headache in Children and Adolescents. Life (Basel). 2021 Jul 13;11(7). doi: 10.3390/life11070684. PMID: 34357056; PMCID: PMC8303920.
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Life (Basel). 2021 Jul 13;11(7). doi: 10.3390/life11070684.

Outcomes of Migraine and Tension-Type Headache in Children and Adolescents.

Life (Basel, Switzerland)

Jacob Genizi, Ayellet Hendler-Sade, Idan Segal, Ellen Bamberger, Isaac Srugo, Nogah C Kerem

Affiliations

  1. Pediatric Neurology Unit, Bnai Zion Medical Center, Haifa 31048, Israel.
  2. Pediatric Department, Bnai Zion Medical Center, Haifa 31048, Israel.
  3. Bruce Rappaport Faulty of Medicine, Technion, Haifa 31048, Israel.
  4. Adolescent Medicine Unit, Bnai Zion Medical Center, Haifa 31048, Israel.

PMID: 34357056 PMCID: PMC8303920 DOI: 10.3390/life11070684

Abstract

The aim of our study was to evaluate the long-term outcomes of pediatric migraine and TTH in a clinical setting. We conducted a cohort study. Pediatric patients who visited the pediatric neurology clinic due to diagnoses of migraine or TTH were contacted by phone 8-10 years after their initial diagnosis and interviewed about their outcomes. Of 147 children, we were able to reach 120 (81%) patients. Of these 120 patients, 59 were seen initially due to migraine and 61 due to TTH. For the migraine patients, headaches improved in 48 (81.4%) and worsened in four (6.8%). Regarding diagnosis at follow-up, 59% still had migraine, 17% had TTH, and 23% were headache-free. Aura and photophobia were significantly associated with persistence of a migraine diagnosis. For the TTH patients, headaches improved in 49 (81.7%) and worsened in nine (15.0%). Regarding diagnosis at follow-up, 36.7% still had TTH, 18.3% had migraine, and 45% were headache-free. Of the patients with TTH, 36.7% retained their initial diagnosis compared to 59.3% among the migraine patients. Most pediatric patients presenting with migraine or TTH will experience a favorable outcome over 10 years, with TTH patients having twice the chance of complete resolution.

Keywords: change; diagnosis; outcome; pediatric; primary headaches

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