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Showing 1 to 12 of 217 entries
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Crambines C1 and C2: Two Further Ichthyotoxic Guanidine Alkaloids from the Sponge Crambe crambe.

Journal of natural products

Berlinck RG, Braekman JC, Daloze D, Bruno I, Riccio R, Rogeau D, Amade P.
PMID: 24697558
J Nat Prod. 1992 Apr 01;55(4):528-32. doi: 10.1021/np50082a026.

No abstract available.

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

NPJ breast cancer

Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O, van 't Veer L.
PMID: 28948212
NPJ Breast Cancer. 2017 Aug 25;3:31. doi: 10.1038/s41523-017-0025-7. eCollection 2017.

Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature. However, not all triple negative patients achieved pathologic complete response...

Multiple Autoregulation of Nodulation (AON) Signals Identified through Split Root Analysis of Medicago truncatula sunn and rdn1 Mutants.

Plants (Basel, Switzerland)

Kassaw T, Bridges W, Frugoli J.
PMID: 27135324
Plants (Basel). 2015 Apr 27;4(2):209-24. doi: 10.3390/plants4020209.

Nodulation is energetically costly to the host: legumes balance the nitrogen demand with the energy expense by limiting the number of nodules through long-distance signaling. A split root system was used to investigate systemic autoregulation of nodulation (AON) in...

Peptides with 6-Aminohexanoic Acid: Synthesis and Evaluation as Plasmin Inhibitors.

International journal of peptide research and therapeutics

Purwin M, Markowska A, Bruzgo I, Rusak T, Surażyński A, Jaworowska U, Midura-Nowaczek K.
PMID: 28491013
Int J Pept Res Ther. 2017;23(2):235-245. doi: 10.1007/s10989-016-9555-3. Epub 2016 Sep 19.

Fifteen new peptide derivatives of ɛ-aminocaproic acid (EACA) containing the known fragment -Ala-Phe-Lys- with an affinity for plasmin were synthesised in the present study. The synthesis was carried out a solid phase. The following compounds were synthesised: H-Phe-Lys-EACA-X, H-d-Ala-Phe-Lys-EACA-X,...

Relationship between the histological degrees of hepatitis and the postoperative recurrence of hepatocellular carcinoma in patients with hepatitis C.

Hepatology research : the official journal of the Japan Society of Hepatology

Matsumoto K, Yoshimoto J, Sugo H, Kojima K, Futagawa S, Matsumoto T.
PMID: 12076715
Hepatol Res. 2002 Jul;23(3):196-201. doi: 10.1016/s1386-6346(01)00180-2.

The relationship between the recurrence of hepatocellular carcinoma (HCC) and the degree of inflammation was evaluated in resected livers with the hepatitis C virus (HCV) -associated HCC. Seventy-three patients with HCV-associated HCC who were followed up for more than...

Monitoring of procainamide and N-acetylprocainamide concentration in saliva after oral administration of procainamide.

American journal of therapeutics

Koike Y, Mineshita S, Uchiyama Y, Shudo I, Shimamura K, Togashi H, Saito H.
PMID: 11862226
Am J Ther. 1996 Oct;3(10):708-14. doi: 10.1097/00045391-199610000-00006.

The aim of this study was to evaluate saliva as a potential monitoring medium for procainamide (PA) and its metabolite, N-acetylprocainamide (NAPA). Saliva concentrations of PA and NAPA were determined both in single and repeated oral administration of PA...

Pietro Grocco.

Scientia medica italica. English ed

FRUGONI C.
PMID: 13442668
Sci Med Ital. 1957 Jan-Mar;5(3):393-7.

No abstract available.

Wood anatomy and wood density in shrubs: Responses to varying aridity along transcontinental transects.

American journal of botany

Martínez-Cabrera HI, Jones CS, Espino S, Schenk HJ.
PMID: 21628286
Am J Bot. 2009 Aug;96(8):1388-98. doi: 10.3732/ajb.0800237. Epub 2009 Jul 10.

Wood density plays a key role in ecological strategies and life history variation in woody plants, but little is known about its anatomical basis in shrubs. We quantified the relationships between wood density, anatomy, and climate in 61 shrub...

Genetics in osteoarthritis.

Current genomics

Fernández-Moreno M, Rego I, Carreira-Garcia V, Blanco FJ.
PMID: 19516961
Curr Genomics. 2008 Dec;9(8):542-7. doi: 10.2174/138920208786847953.

Osteoarthritis is a degenerative articular disease with complex pathogeny because diverse factors interact causing a process of deterioration of the cartilage. Despite the multifactorial nature of this pathology, from the 50's it s known that certain forms of osteoarthritis...

RNAi Phenotypes and the Localization of a Protein::GUS Fusion Imply a Role for Medicago truncatula PIN Genes in Nodulation.

Journal of plant growth regulation

Huo X, Schnabel E, Hughes K, Frugoli J.
PMID: 19444321
J Plant Growth Regul. 2006 Jun;25(2):156-165. doi: 10.1007/s00344-005-0106-y. Epub 2006 Jun 19.

The symbiosis between legumes and rhizobia results in the development of a new plant organ, the nodule. A role for polar auxin transport in nodule development in Medicago truncatula has been demonstrated using molecular genetic tools. The expression of...

A complete structural performance analysis and modelling of hydroxyapatite scaffolds with variable porosity.

Computer methods in biomechanics and biomedical engineering

Gallegos-Nieto E, Medellín-Castillo HI, de Lange DF.
PMID: 24579777
Comput Methods Biomech Biomed Engin. 2015 Aug;18(11):1225-1237. doi: 10.1080/10255842.2014.889690. Epub 2014 Feb 28.

The use of hydroxyapatite (HA) scaffolds for bone regeneration is an alternative procedure to treat bone defects due to cancer, other diseases or traumas. Although the use of HA has been widely studied in the literature, there are still...

Multifactor dimensionality reduction reveals a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis.

BioData mining

Collins RL, Hu T, Wejse C, Sirugo G, Williams SM, Moore JH.
PMID: 23418869
BioData Min. 2013 Feb 18;6(1):4. doi: 10.1186/1756-0381-6-4.

BACKGROUND: Identifying high-order genetics associations with non-additive (i.e. epistatic) effects in population-based studies of common human diseases is a computational challenge. Multifactor dimensionality reduction (MDR) is a machine learning method that was designed specifically for this problem. The goal...

Showing 1 to 12 of 217 entries