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J Am Heart Assoc. 2021 Oct 19;10(20):e021560. doi: 10.1161/JAHA.120.021560. Epub 2021 Oct 08.

Effect of Religious Fasting in Ramadan on Blood Pressure: Results From LORANS (London Ramadan Study) and a Meta-Analysis.

Journal of the American Heart Association

Rami Al-Jafar, Maria Zografou Themeli, Sadia Zaman, Sharmin Akbar, Victor Lhoste, Ahlam Khamliche, Paul Elliott, Konstantinos K Tsilidis, Abbas Dehghan

Affiliations

  1. Department of Epidemiology and Biostatistics School of Public Health Imperial College London London United Kingdom.
  2. Klinik for Obstetrics and Gynaecology Kantonsspital Schaffhausen Bern Switzerland.
  3. School of Medicine Imperial College London London United Kingdom.
  4. Department of Chemistry Imperial College London London United Kingdom.
  5. Dementia Research Institute at Imperial College London London United Kingdom.
  6. National Institute for Health Research Imperial College Biomedical Research Centre Imperial College London London United Kingdom.
  7. Department of Hygiene and Epidemiology University of Ioannina School of Medicine Ioannina Greece.
  8. MRC-PHE Centre for Environment and Health, School of Public Health Imperial College London London United Kingdom.

PMID: 34619991 DOI: 10.1161/JAHA.120.021560

Abstract

Background Ramadan fasting is practiced by hundreds of millions every year. This ritual practice changes diet and lifestyle dramatically; thus, the effect of Ramadan fasting on blood pressure must be determined. Methods and Results LORANS (London Ramadan Study) is an observational study, systematic review, and meta-analysis. In LORANS, we measured systolic blood pressure (SBP) and diastolic blood pressure (DBP) of 85 participants before and right after Ramadan. In the systematic review, studies were retrieved from PubMed, Embase, and Scopus from inception to March 3, 2020. We meta-analyzed the effect from these studies and unpublished data from LORANS. We included observational studies that measured SBP and/or DBP before Ramadan and during the last 2 weeks of Ramadan or the first 2 weeks of the month after. Data appraisal and extraction were conducted by at least 2 reviewers in parallel. We pooled SBP and DBP using a random-effects model. The systematic review is registered with PROSPERO (International Prospective Register of Systematic Reviews; CRD42019159477). In LORANS, 85 participants were recruited; mean age was 45.6±15.9 years, and 52.9% (

Keywords: Ramadan fasting; diastolic blood pressure; hypertension; meta‐analysis; systematic review; systolic blood pressure

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