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Aboellail TA, Waugh M, Harvey A, et al. Neoplasia and Proliferative Lesions of New World Camelids: A Systematic Literature Review and Retrospective Study of Cases Submitted to Colorado State University From 1995 to 2020. Front Vet Sci. 2021;8:743498doi: 10.3389/fvets.2021.743498.
Aboellail, T. A., Waugh, M., Harvey, A., Fisher, J., & Vilander, A. C. (2021). Neoplasia and Proliferative Lesions of New World Camelids: A Systematic Literature Review and Retrospective Study of Cases Submitted to Colorado State University From 1995 to 2020. Frontiers in veterinary science, 8743498. https://doi.org/10.3389/fvets.2021.743498
Aboellail, Tawfik A, et al. "Neoplasia and Proliferative Lesions of New World Camelids: A Systematic Literature Review and Retrospective Study of Cases Submitted to Colorado State University From 1995 to 2020." Frontiers in veterinary science vol. 8 (2021): 743498. doi: https://doi.org/10.3389/fvets.2021.743498
Aboellail TA, Waugh M, Harvey A, Fisher J, Vilander AC. Neoplasia and Proliferative Lesions of New World Camelids: A Systematic Literature Review and Retrospective Study of Cases Submitted to Colorado State University From 1995 to 2020. Front Vet Sci. 2021 Oct 22;8:743498. doi: 10.3389/fvets.2021.743498. eCollection 2021. PMID: 34746283; PMCID: PMC8569619.
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Front Vet Sci. 2021 Oct 22;8:743498. doi: 10.3389/fvets.2021.743498. eCollection 2021.

Neoplasia and Proliferative Lesions of New World Camelids: A Systematic Literature Review and Retrospective Study of Cases Submitted to Colorado State University From 1995 to 2020.

Frontiers in veterinary science

Tawfik A Aboellail, Max Waugh, Alexandra Harvey, Jade Fisher, Allison C Vilander

Affiliations

  1. Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, United States.
  2. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  3. Antech Diagnostics, Fountain Valley, CA, United States.

PMID: 34746283 PMCID: PMC8569619 DOI: 10.3389/fvets.2021.743498

Abstract

Camelid pathology submissions to veterinary diagnostic laboratories are on the rise given the increasing popularity and population of llamas and alpacas especially in the western United States. When compared to other animals, the field of camelid neoplasia has a relative paucity of cases reported in the literature. The Colorado State University Veterinary Diagnostic Laboratories (CSU-VDL) has had a steady increase in the numbers of camelid pathology submissions allowing for a robust review of diagnoses of neoplasia in new world camelids. Here we present a retrospective analysis of camelid neoplastic and proliferative lesions diagnosed at the CSU-VDL from 1995 to 2020, followed by an extensive literature review. Results show increasing incidence of camelid neoplasia reported in the literature, therefore becoming a common diagnosis in llamas and alpacas. Proliferative and neoplastic lesions were diagnosed in 8.8% of new world camelid submissions to CSU-VDL with the most common tumors being lymphomas, squamous cell carcinomas, fibromas, and adenocarcinomas. Risk factors are female sex and increased age except in the case of lymphoma, which tends to occur in younger camelids. Lymphomas, melanomas, and adenocarcinomas (especially of gastrointestinal tract) carry an increased risk of multiple-organ system involvement often with widespread metastases. Conditions described in camelids for the first time include osteosarcoma, cutaneous hemangiosarcoma, myxosarcoma, pilomatricoma, ovarian theca cell tumor, congenital nevus with malignant transformation, and various other neoplasia. This article will provide an operational guide for camelid neoplasia to further assist veterinary laboratory diagnosticians, researchers, and practicing veterinarians in the field of camelid medicine and pathology.

Copyright © 2021 Aboellail, Waugh, Harvey, Fisher and Vilander.

Keywords: alpaca; llama; neoplasia; new world camelid; proliferative lesions

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. BMC Vet Res. 2019 May 9;15(1):139 - PubMed
  2. J Vet Diagn Invest. 1997 Apr;9(2):210-3 - PubMed
  3. J Vet Diagn Invest. 2000 Sep;12(5):473-6 - PubMed
  4. Vet Dermatol. 2011 Feb;22(1):2-16 - PubMed
  5. Vet Pathol. 2000 Nov;37(6):680-3 - PubMed
  6. Vet Rec. 2003 Apr 19;152(16):507-8 - PubMed
  7. J Vet Diagn Invest. 2009 Jan;21(1):141-4 - PubMed
  8. Can Vet J. 2004 Nov;45(11):938-40 - PubMed
  9. Vet Radiol Ultrasound. 2005 Jan-Feb;46(1):65-8 - PubMed
  10. Can Vet J. 2010 Dec;51(12):1379-82 - PubMed
  11. J Am Vet Med Assoc. 2008 Apr 15;232(8):1206-9 - PubMed
  12. Vet Pathol. 2004 Sep;41(5):520-3 - PubMed
  13. J Am Vet Med Assoc. 2013 Sep 1;243(5):645-7 - PubMed
  14. J Vet Diagn Invest. 2009 Mar;21(2):280-2 - PubMed
  15. J Vet Diagn Invest. 2009 Jan;21(1):171-3 - PubMed
  16. J Vet Intern Med. 2012 Jul-Aug;26(4):1073-7 - PubMed
  17. Can Vet J. 1996 Jul;37(7):426-8 - PubMed
  18. Vet Pathol. 2009 Mar;46(2):288-98 - PubMed
  19. J Vet Diagn Invest. 2007 Mar;19(2):202-4 - PubMed
  20. J Vet Diagn Invest. 2010 Sep;22(5):808-11 - PubMed
  21. J Am Vet Med Assoc. 1997 Jun 15;210(12):1784-7 - PubMed
  22. Can Vet J. 2005 Apr;46(4):317-8 - PubMed
  23. J Vet Diagn Invest. 2019 Mar;31(2):280-283 - PubMed
  24. J Comp Pathol. 2014 Jul;151(1):51-6 - PubMed
  25. J Vet Diagn Invest. 2012 Sep;24(5):986-9 - PubMed
  26. Vet Clin North Am Food Anim Pract. 1989 Mar;5(1):101-43 - PubMed
  27. J Vet Diagn Invest. 1993 Jan;5(1):117-21 - PubMed
  28. Can Vet J. 1997 Oct;38(10):643-4 - PubMed
  29. Vet Rec. 2008 Feb 9;162(6):188-9 - PubMed
  30. J Vet Diagn Invest. 2002 Jul;14(4):328-31 - PubMed
  31. Vet Ophthalmol. 2008 Mar-Apr;11(2):111-3 - PubMed
  32. Vet Pathol. 2003 Jan;40(1):103-7 - PubMed
  33. Vet Clin Pathol. 2008 Sep;37(3):289-97 - PubMed
  34. Cornell Vet. 1988 Jul;78(3):235-41 - PubMed
  35. J Am Vet Med Assoc. 2013 Oct 15;243(8):1113-5 - PubMed
  36. J Am Vet Med Assoc. 2006 May 1;228(9):1343-4 - PubMed
  37. J Am Vet Med Assoc. 1985 Dec 1;187(11):1245-6 - PubMed
  38. Can Vet J. 2001 Oct;42(10):805-6 - PubMed
  39. Can Vet J. 2001 Nov;42(11):872-4 - PubMed
  40. Vet Rec Open. 2019 May 3;6(1):e000239 - PubMed
  41. J Vet Diagn Invest. 2013 Jan;25(1):168-72 - PubMed
  42. J Vet Diagn Invest. 2006 Nov;18(6):605-7 - PubMed
  43. J Vet Diagn Invest. 2007 Jul;19(4):450-3 - PubMed
  44. J Am Vet Med Assoc. 1974 Nov 1;165(9):820-2 - PubMed
  45. J Vet Intern Med. 1995 Nov-Dec;9(6):381-5 - PubMed
  46. J Vet Dent. 2011 Spring;28(1):22-4 - PubMed
  47. J Vet Diagn Invest. 2016 Jul;28(4):469-72 - PubMed
  48. Vet Radiol Ultrasound. 2006 Oct-Nov;47(6):571-3 - PubMed
  49. Can Vet J. 2003 Oct;44(10):824-7 - PubMed
  50. J Zoo Wildl Med. 2005 Dec;36(4):706-8 - PubMed
  51. J Am Vet Med Assoc. 2015 Mar 15;246(6):674-80 - PubMed
  52. Vet Clin Pathol. 2015 Sep;44(3):459-60 - PubMed
  53. Can Vet J. 2012 Mar;53(3):283-6 - PubMed
  54. Vet Radiol Ultrasound. 2010 May-Jun;51(3):311-2 - PubMed
  55. Vet J. 2006 Jan;171(1):181-5 - PubMed
  56. Vet J. 2008 Jan;175(1):133-5 - PubMed
  57. J Am Vet Med Assoc. 1997 Mar 15;210(6):808-10 - PubMed
  58. J Vet Diagn Invest. 1997 Jan;9(1):103-6 - PubMed
  59. J Am Vet Med Assoc. 1990 Nov 1;197(9):1157-62 - PubMed
  60. Vet Dermatol. 2011 Jun;22(3):275-8 - PubMed
  61. BMC Vet Res. 2020 Nov 9;16(1):429 - PubMed
  62. J Vet Diagn Invest. 2006 Sep;18(5):499-503 - PubMed
  63. J Vet Intern Med. 2005 Mar-Apr;19(2):271-4 - PubMed
  64. Vet Pathol. 1988 Jul;25(4):329-30 - PubMed
  65. J Vet Diagn Invest. 2019 Nov;31(6):913-916 - PubMed
  66. J Comp Pathol. 2002 Jul;127(1):69-71 - PubMed
  67. Vet Rec. 2013 Jun 22;172(25):666-7 - PubMed
  68. J Vet Diagn Invest. 2004 Jan;16(1):89-92 - PubMed
  69. J Am Vet Med Assoc. 2020 Jul 1;257(1):45-47 - PubMed
  70. Arch Dermatol. 2004 Jan;140(1):83-8 - PubMed
  71. J Am Vet Med Assoc. 2020 Jul 1;257(1):49-52 - PubMed
  72. J Vet Diagn Invest. 2006 May;18(3):303-6 - PubMed
  73. Can Vet J. 2001 Mar;42(3):204-6 - PubMed
  74. J Am Vet Med Assoc. 1990 Jun 15;196(12):2009-10 - PubMed
  75. Can Vet J. 2010 Oct;51(10):1157-60 - PubMed
  76. Can Vet J. 2010 Dec;51(12):1387-90 - PubMed
  77. Vet Ophthalmol. 2005 Jul-Aug;8(4):287-90 - PubMed
  78. J Vet Diagn Invest. 2004 May;16(3):226-9 - PubMed
  79. Vet Res Commun. 2005 Feb;29(2):137-40 - PubMed

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