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Front Aging Neurosci. 2021 Nov 30;13:773984. doi: 10.3389/fnagi.2021.773984. eCollection 2021.

The Neutrophil to Lymphocyte Ratio Is Associated With the Risk of Subsequent Dementia in the Framingham Heart Study.

Frontiers in aging neuroscience

Jaime Ramos-Cejudo, Andrew D Johnson, Alexa Beiser, Sudha Seshadri, Joel Salinas, Jeffrey S Berger, Nathanael R Fillmore, Nhan Do, Chunlei Zheng, Zanetta Kovbasyuk, Babak A Ardekani, Omonigho M Bubu, Ankit Parekh, Antonio Convit, Rebecca A Betensky, Thomas M Wisniewski, Ricardo S Osorio

Affiliations

  1. Department of Psychiatry, New York University Grossman School of Medicine, New York, NY, United States.
  2. VA Boston Cooperative Studies Program, MAVERIC, VA Boston Healthcare System, Boston, MA, United States.
  3. Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA, United States.
  4. The Framingham Heart Study, Boston, MA, United States.
  5. Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States.
  6. Department of Neurology, Boston University School of Medicine, Boston, MA, United States.
  7. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
  8. Department of Neurology, Center for Cognitive Neurology, NYU Grossman School of Medicine, New York, NY, United States.
  9. Division of Vascular Surgery, Department of Surgery, NYU Grossman School of Medicine, New York, NY, United States.
  10. Division of Cardiology and Hematology, Department of Medicine, NYU Grossman School of Medicine, New York, NY, United States.
  11. Center for the Prevention of Cardiovascular Disease, NYU Grossman School of Medicine, New York, NY, United States.
  12. Harvard Medical School, Boston, MA, United States.
  13. Boston University School of Medicine, Boston, MA, United States.
  14. Nathan Kline Institute, Orangeburg, NY, United States.
  15. Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  16. Department of Biostatistics, New York University School of Global Public Health, New York, NY, United States.
  17. Department of Pathology, NYU Grossman School of Medicine, New York, NY, United States.

PMID: 34916927 PMCID: PMC8670436 DOI: 10.3389/fnagi.2021.773984

[No abstract available.]

Copyright © 2021 Ramos-Cejudo, Johnson, Beiser, Seshadri, Salinas, Berger, Fillmore, Do, Zheng, Kovbasyuk, Ardekani, Bubu, Parekh, Convit, Betensky, Wisniewski and Osorio.

Keywords: Alzheimer’s disease; FHS; Framingham; NLR; complete blood count (CBC); dementia; neutrophil to lymphocyte ratio; risk prediction

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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