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Circulation. 2021 Nov 30;144(22):1777-1794. doi: 10.1161/CIRCULATIONAHA.121.055313. Epub 2021 Oct 25.

Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.

Circulation

Amanda Sánchez-López, Carla Espinós-Estévez, Cristina González-Gómez, Pilar Gonzalo, María J Andrés-Manzano, Víctor Fanjul, Raquel Riquelme-Borja, Magda R Hamczyk, Álvaro Macías, Lara Del Campo, Emilio Camafeita, Jesús Vázquez, Anna Barkaway, Loïc Rolas, Sussan Nourshargh, Beatriz Dorado, Ignacio Benedicto, Vicente Andrés

Affiliations

  1. Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain (A.S.-L., C.E.-E., C.G.-G., P.G., M.J.A.-M., V.F., R.R.-B., M.R.H., A.M., L.d.C., E.C., J.V., B.D., I.B., V.A.).
  2. Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain (A.S.-L., C.G.-G., P.G., M.J.A.-M., V.F., M.R.H., A.M., L.d.C., E.C., J.V., B.D., V.A.).
  3. Now with Departamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Spain (M.R.H.).
  4. Now with Departamento de Biología Celular, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain (L.d.C.).
  5. Centre for Microvascular Research, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (A.B., L.R., S.N.).

PMID: 34694158 PMCID: PMC8614561 DOI: 10.1161/CIRCULATIONAHA.121.055313

[No abstract available.]

Keywords: Hutchinson-Gilford progeria syndrome; cardiac myocyte; cell; smooth muscle

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