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Davis JW, Auerbach A, Crothers BA, et al. Intravascular Large B-Cell Lymphoma. Arch Pathol Lab Med. 2021;doi: 10.5858/arpa.2021-0165-RA.
Davis, J. W., Auerbach, A., Crothers, B. A., Lewin, E., Lynch, D. T., Teschan, N. J., & Schmieg, J. J. (2021). Intravascular Large B-Cell Lymphoma. Archives of pathology & laboratory medicine, . https://doi.org/10.5858/arpa.2021-0165-RA
Davis, Joshua W, et al. "Intravascular Large B-Cell Lymphoma." Archives of pathology & laboratory medicine vol. (2021). doi: https://doi.org/10.5858/arpa.2021-0165-RA
Davis JW, Auerbach A, Crothers BA, Lewin E, Lynch DT, Teschan NJ, Schmieg JJ. Intravascular Large B-Cell Lymphoma. Arch Pathol Lab Med. 2021 Jan 03; doi: 10.5858/arpa.2021-0165-RA. Epub 2021 Jan 03. PMID: 34979566.
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Arch Pathol Lab Med. 2021 Jan 03; doi: 10.5858/arpa.2021-0165-RA. Epub 2021 Jan 03.

Intravascular Large B-Cell Lymphoma.

Archives of pathology & laboratory medicine

Joshua W Davis, Aaron Auerbach, Barbara A Crothers, Eleanor Lewin, David T Lynch, Nathan J Teschan, John J Schmieg

Affiliations

  1. From Clinical and Anatomic Pathology Residency Program, Walter Reed National Military Medical Center, Bethesda, Maryland (Davis).
  2. The Joint Pathology Center, Silver Spring, Maryland (Auerbach, Crothers, Schmieg III).
  3. the Department of Pathology, Women & Infants Hospital, Providence, Rhode Island (Lewin).
  4. and the Department of Pathology, Brooke Army Medical Center, Fort Sam Houston, Texas (Lynch, Teschan).

PMID: 34979566 DOI: 10.5858/arpa.2021-0165-RA

Abstract

CONTEXT.—: Intravascular large B-cell lymphoma (IVLBCL) is a rare hematopathologic entity, posing both a clinical and histologic challenge for diagnosis. Numerous pitfalls can hinder making the diagnosis.

OBJECTIVE.—: To summarize recent developments in literature pertaining to IVLBCL and point out key pitfalls pathologists should be prepared to encounter.

DATA SOURCES.—: Literature review via PubMed search and hospital (Darnall Medical Library) resources.

CONCLUSIONS.—: The 3 primary pitfalls of IVLBCL include masking of IVLBCL, mimicry by IVLBCL, and mimicry of IVLBCL. These scenarios illustrate the importance of histologic pattern recognition and subsequent usage of immunohistochemistry, especially in context of a clinical history that may be noncharacteristic.

© 2022 College of American Pathologists.

Conflict of interest statement

The views expressed in this article are those of the authors and do not reflect the official policy of the Department of Army/Navy/Air Force, Department of Defense, or US government.

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