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Trends Cancer. 2021 Oct;7(10):886-890. doi: 10.1016/j.trecan.2021.07.004. Epub 2021 Aug 20.

Converging technologies: targeting the hallmarks of cancer using ultrasound and microbubbles.

Trends in cancer

Janith Wanigasekara, Andressa Maria Aguiar de Carvalho, Patrick J Cullen, Brijesh Tiwari, James F Curtin

Affiliations

  1. BioPlasma Research Group, School of Food Science and Environmental Health, Technological University Dublin, Dublin, Ireland; Department of Food Biosciences, Teagasc Food Research Centre, Ashtown, Dublin, Ireland; Environmental Sustainability & Health Institute (ESHI), Technological University Dublin, Dublin, Ireland.
  2. BioPlasma Research Group, School of Food Science and Environmental Health, Technological University Dublin, Dublin, Ireland; University of Sydney, School of Chemical and Biomolecular Engineering, Sydney, Australia.
  3. Department of Food Biosciences, Teagasc Food Research Centre, Ashtown, Dublin, Ireland.
  4. BioPlasma Research Group, School of Food Science and Environmental Health, Technological University Dublin, Dublin, Ireland; Environmental Sustainability & Health Institute (ESHI), Technological University Dublin, Dublin, Ireland; FOCAS Research Institute, Technological University Dublin, Dublin, Ireland. Electronic address: [email protected].

PMID: 34426143 DOI: 10.1016/j.trecan.2021.07.004

Abstract

Various complex biological effects occur when ultrasonic compression waves travel through biological material. The myriad of biological outcomes instigated by ultrasound are evident when viewed through the lens of the hallmarks of cancer. Herein, we summarise the therapeutic potential of ultrasound, enhanced by microbubbles, for the treatment of cancer.

Copyright © 2021 Elsevier Inc. All rights reserved.

Keywords: cancer; hallmarks; microbubbles; targeted therapy; ultrasound

Conflict of interest statement

Declaration of interests No interests are declared.

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