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Showing 1 to 12 of 15 entries
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Development of molecular imaging and nanomedicine in China.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Shen B, Kezheng W, Xilin S, Lina W.
PMID: 21850712
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 Nov-Dec;3(6):533-44. doi: 10.1002/wnan.156. Epub 2011 Aug 17.

The rapid progress of molecular imaging (MI) and the application of nanotechnology in medicine have the potential to advance the foundations of diagnosis, treatment, and prevention of diseases. Although MI and biomedical nanotechnology are still in a formative phase...

For Whom the Bubble Grows: Physical Principles of Bubble Nucleation and Dynamics in Histotripsy Ultrasound Therapy.

Ultrasound in medicine & biology

Bader KB, Vlaisavljevich E, Maxwell AD.
PMID: 30922619
Ultrasound Med Biol. 2019 May;45(5):1056-1080. doi: 10.1016/j.ultrasmedbio.2018.10.035. Epub 2019 Mar 26.

Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of bubble clouds for tissue destruction. Although acoustic bubble activity is often characterized as chaotic, the...

Enhancing carrier flux for efficient drug delivery in cancer tissues.

Biophysical journal

Arango-Restrepo A, Rubi JM, Kjelstrup S, Angelsen BAJ, Davies CL.
PMID: 34757075
Biophys J. 2021 Dec 07;120(23):5255-5266. doi: 10.1016/j.bpj.2021.10.036. Epub 2021 Oct 30.

Ultrasound focused toward tumors in the presence of circulating microbubbles improves the delivery of drug-loaded nanoparticles and therapeutic outcomes; however, the efficacy varies among the different properties and conditions of the tumors. Therefore, there is a need to optimize...

Enhancing carrier flux for efficient drug delivery in cancer tissues.

Biophysical journal

Arango-Restrepo A, Rubi JM, Kjelstrup S, Angelsen BAJ, Davies CL.
PMID: 34757075
Biophys J. 2021 Dec 07;120(23):5255-5266. doi: 10.1016/j.bpj.2021.10.036. Epub 2021 Oct 30.

Ultrasound focused toward tumors in the presence of circulating microbubbles improves the delivery of drug-loaded nanoparticles and therapeutic outcomes; however, the efficacy varies among the different properties and conditions of the tumors. Therefore, there is a need to optimize...

The Potential for Retained Microbubbles: To Imaging . . . and Beyond.

Journal of the American College of Cardiology

Porter TR.
PMID: 34763777
J Am Coll Cardiol. 2021 Nov 16;78(20):2001-2003. doi: 10.1016/j.jacc.2021.08.069.

No abstract available.

Imaging Microbubbles in Children: A Light Foot on the Gas.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

Burns PN.
PMID: 33599310
J Ultrasound Med. 2021 Dec;40(12):2535-2536. doi: 10.1002/jum.15656. Epub 2021 Feb 18.

No abstract available.

Converging technologies: targeting the hallmarks of cancer using ultrasound and microbubbles.

Trends in cancer

Wanigasekara J, de Carvalho AMA, Cullen PJ, Tiwari B, Curtin JF.
PMID: 34426143
Trends Cancer. 2021 Oct;7(10):886-890. doi: 10.1016/j.trecan.2021.07.004. Epub 2021 Aug 20.

Various complex biological effects occur when ultrasonic compression waves travel through biological material. The myriad of biological outcomes instigated by ultrasound are evident when viewed through the lens of the hallmarks of cancer. Herein, we summarise the therapeutic potential...

A flow focusing microfluidic device with an integrated Coulter particle counter for production, counting and size characterization of monodisperse microbubbles.

Lab on a chip

Rickel JMR, Dixon AJ, Klibanov AL, Hossack JA.
PMID: 30070301
Lab Chip. 2018 Aug 21;18(17):2653-2664. doi: 10.1039/c8lc00496j.

Flow focusing microfluidic devices (FFMDs) have been investigated for the production of monodisperse populations of microbubbles for chemical, biomedical and mechanical engineering applications. High-speed optical microscopy is commonly used to monitor FFMD microbubble production parameters, such as diameter and...

Micro-Bio-Chemo-Mechanical-Systems: Micromotors, Microfluidics, and Nanozymes for Biomedical Applications.

Advanced materials (Deerfield Beach, Fla.)

Mujtaba J, Liu J, Dey KK, Li T, Chakraborty R, Xu K, Makarov D, Barmin RA, Gorin DA, Tolstoy VP, Huang G, Solovev AA, Mei Y.
PMID: 33893682
Adv Mater. 2021 Jun;33(22):e2007465. doi: 10.1002/adma.202007465. Epub 2021 Apr 23.

Wireless nano-/micromotors powered by chemical reactions and/or external fields generate motive forces, perform tasks, and significantly extend short-range dynamic responses of passive biomedical microcarriers. However, before micromotors can be translated into clinical use, several major problems, including the biocompatibility...

Complex Highways on the Translational Roadmap for Therapeutic Ultrasound-Targeted Microbubble Cavitation: Where Are We Now?.

JACC. Cardiovascular imaging

Villanueva FS, Chen X.
PMID: 31607657
JACC Cardiovasc Imaging. 2020 Mar;13(3):652-654. doi: 10.1016/j.jcmg.2019.08.010. Epub 2019 Oct 11.

No abstract available.

Particle motion induced by bubble cavitation.

Physical review letters

Poulain S, Guenoun G, Gart S, Crowe W, Jung S.
PMID: 26066438
Phys Rev Lett. 2015 May 29;114(21):214501. doi: 10.1103/PhysRevLett.114.214501. Epub 2015 May 27.

Cavitation bubbles induce impulsive forces on surrounding substrates, particles, or surfaces. Even though cavitation is a traditional topic in fluid mechanics, current understanding and studies do not capture the effect of cavitation on suspended objects in fluids. In the...

Contrast echocardiography: mechanism of action, safety and clinical applications.

Minerva cardioangiologica

Soliman OI, De Jong N, Van Der Zwaan HB, Galema TW, Vletter WB, Van Dalen BM, Schinkel AF, Ten Cate FJ, Geleijnse ML.
PMID: 20485240
Minerva Cardioangiol. 2010 Jun;58(3):343-55.

Since its initial description by Gramiak and Shah in 1968, contrast echocardiography has become an established practice world-wide. Microbubbles have the unique property of being pure intravascular tracers. The basic rationale behind bubble imaging is the characteristic responses to...

Showing 1 to 12 of 15 entries