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Cancer Genet. 2011 Feb;204(2):57-67. doi: 10.1016/j.cancergencyto.2010.10.003.

Cytogenomic aberrations associated with prostate cancer.

Cancer genetics

Guangyu Gu, Arthur R Brothman

Affiliations

  1. ARUP Institute for Clinical and Experimental Pathology, ARUP Laboratories, Salt Lake City, UT, USA.

PMID: 21504704 DOI: 10.1016/j.cancergencyto.2010.10.003

Abstract

Genetic changes associated with prostate cancer have finally begun to elucidate some of the mechanisms involved in the etiology of this complex and common disease. We highlight consistent and relatively frequent abnormalities seen by various methodologies. Specifically, the results of conventional and molecular cytogenetic studies, genome-wide association studies with single nucleotide polymorphisms, recurrent gene fusions, and epigenetic analyses are discussed.

Copyright © 2011 Elsevier Inc. All rights reserved.

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