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J Periodontal Implant Sci. 2011 Oct;41(5):242-7. doi: 10.5051/jpis.2011.41.5.242. Epub 2011 Oct 31.

The effect of fibronectin-coated implant on canine osseointegration.

Journal of periodontal & implant science

Sungtae Kim, Woo-Chun Myung, Jung-Seok Lee, Jae-Kook Cha, Ui-Won Jung, Hyeong-Cheol Yang, In-Seop Lee, Seong-Ho Choi

Affiliations

  1. Department of Prosthodontics, Yonsei University College of Dentistry, Seoul, Korea.

PMID: 22087415 PMCID: PMC3213235 DOI: 10.5051/jpis.2011.41.5.242

Abstract

PURPOSE: The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface.

METHODS: Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluation after 4- and 8-week healing periods.

RESULTS: All types of implants were clinically stable without any mobility. Although the bone-to-implant contact and bone density of the SLA implants coated with calcium phosphate (CaP)/fibronectin were lower than the uncoated SLA implants, there were no significant differences between the uncoated SLA surface group and the SLA surface coated with CaP/fibronectin group.

CONCLUSIONS: Within the limits of this study, SLA surfaces coated with CaP/fibronectin were shown to have comparable bone-to-implant contact and bone density to uncoated SLA surfaces.

Keywords: Biocompatible coated materials; Bone density; Calcium phosphate; Dental implants; Fibronectins

References

  1. J Biomed Mater Res A. 2003 Nov 1;67(2):684-8 - PubMed
  2. Clin Implant Dent Relat Res. 2010 Mar;12(1):9-17 - PubMed
  3. Int J Oral Maxillofac Implants. 1995 Nov-Dec;10(6):721-8 - PubMed
  4. J Periodontol. 1990 May;61(5):300-4 - PubMed
  5. J Biomed Mater Res. 1998 Jul;41(1):30-40 - PubMed
  6. J Mater Sci Mater Med. 2008 Mar;19(3):1399-405 - PubMed
  7. Int J Oral Maxillofac Implants. 2007 Sep-Oct;22(5):755-60 - PubMed
  8. Int J Oral Maxillofac Implants. 2006 Nov-Dec;21(6):859-66 - PubMed
  9. J Orthop Res. 1988;6(1):58-62 - PubMed
  10. Proc Inst Mech Eng H. 1998;212(2):137-47 - PubMed
  11. J Biomed Mater Res. 2000 Mar 5;49(3):345-52 - PubMed
  12. Biomed Mater. 2009 Aug;4(4):044107 - PubMed
  13. J Mater Sci Mater Med. 2003 Mar;14(3):195-200 - PubMed
  14. Biomaterials. 1999 Dec;20(23-24):2311-21 - PubMed
  15. Int J Oral Maxillofac Implants. 2010 Mar-Apr;25(2):401-15 - PubMed
  16. J Mater Sci Mater Med. 2004 Feb;15(2):99-107 - PubMed
  17. Acta Biomater. 2010 Jun;6(6):2274-81 - PubMed
  18. Trends Biotechnol. 2010 Apr;28(4):198-206 - PubMed
  19. Biomaterials. 2000 Mar;21(5):469-73 - PubMed
  20. Int J Prosthodont. 1998 Sep-Oct;11(5):391-401 - PubMed
  21. Am J Med. 1980 Apr;68(4):577-94 - PubMed
  22. Clin Implant Dent Relat Res. 2009 Dec;11(4):338-47 - PubMed
  23. Periodontol 2000. 1998 Jun;17:63-76 - PubMed
  24. Cells Tissues Organs. 2001;168(3):178-87 - PubMed
  25. Proc Natl Acad Sci U S A. 1980 Apr;77(4):2074-8 - PubMed
  26. Sci Am. 1986 Jun;254(6):42-51 - PubMed

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