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World J Hepatol. 2016 Nov 18;8(32):1414-1418. doi: 10.4254/wjh.v8.i32.1414.

Spontaneous liver rupture as first sign of polyarteritis nodosa.

World journal of hepatology

Irene Gómez-Luque, Felipe Alconchel, Rubén Ciria, M Dolores Ayllón, Antonio Luque, Marina Sánchez, Pedro López-Cillero, Javier Briceño

Affiliations

  1. Irene Gómez-Luque, General Surgery, Reina Sofía University Hospital, 14004 Córdoba, Spain.

PMID: 27917267 PMCID: PMC5114477 DOI: 10.4254/wjh.v8.i32.1414

Abstract

Polyarteritis nodosa (PAN) is one of the systemic vasculitis that affects the media wall of arteries of small and medium diameter. Diagnosis proves difficult due to the unspecific symptoms that dominate the clinical profile. Liver involvement is very diverse, ranging from the development of cirrhotic liver disease to acute abdomen presentation that requires surgery because of liver rupture. The management of these patients requires an expert multidisciplinary team. There are several cases in the literature that describe a sudden liver rupture as the first manifestation of a PAN. In this paper we present the case of a 75 years old patient without any previous disease, who is subjected to major hepatic resection for spontaneous liver rupture.

Keywords: Liver surgery; Polyarteritis nodosa; Rheumatology; Spontaneous liver rupture; Vasculitis

Conflict of interest statement

Conflict-of-interest statement: Authors declare have no conflicts of interest. The present study did not receive any financial support.

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