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Biomed Opt Express. 2016 Nov 21;7(12):5218-5232. doi: 10.1364/BOE.7.005218. eCollection 2016 Dec 01.

Depth-resolved imaging of colon tumor using optical coherence tomography and fluorescence laminar optical tomography.

Biomedical optics express

Qinggong Tang, Jianting Wang, Aaron Frank, Jonathan Lin, Zhifang Li, Chao-Wei Chen, Lily Jin, Tongtong Wu, Bruce D Greenwald, Hiroshi Mashimo, Yu Chen

Affiliations

  1. Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.
  2. Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA; Key Laboratory of Optoelectronic Science and Technology for Medicine, Ministry of Education, College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, China.
  3. Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14642, USA.
  4. Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
  5. Department of Medicine, Veterans Affairs Boston Healthcare System, Harvard Medical School, West Roxbury, MA 02132, USA.

PMID: 28018738 PMCID: PMC5175565 DOI: 10.1364/BOE.7.005218

Abstract

Early detection of neoplastic changes remains a critical challenge in clinical cancer diagnosis and treatment. Many cancers arise from epithelial layers such as those of the gastrointestinal (GI) tract. Current standard endoscopic technology is difficult to detect the subsurface lesions. In this research, we investigated the feasibility of a novel multi-modal optical imaging approach including high-resolution optical coherence tomography (OCT) and high-sensitivity fluorescence laminar optical tomography (FLOT) for structural and molecular imaging. The C57BL/6J-Apc

Keywords: (110.4190) Multiple imaging; (170.2520) Fluorescence microscopy; (170.3880) Medical and biological imaging; (170.4500) Optical coherence tomography

References

  1. Scand J Gastroenterol. 2005 Jul;40(7):750-8 - PubMed
  2. Phys Med Biol. 2013 Jun 7;58(11):R37-61 - PubMed
  3. Dig Dis Sci. 2011 Jul;56(7):1996-2000 - PubMed
  4. Am J Respir Crit Care Med. 2015 Dec 15;192(12 ):1504-13 - PubMed
  5. Rev Sci Instrum. 2009 Apr;80(4):043706 - PubMed
  6. Opt Lett. 2005 Jul 15;30(14):1803-5 - PubMed
  7. Science. 2004 Aug 13;305(5686):1007-9 - PubMed
  8. Opt Express. 2004 Jan 26;12(2):249-59 - PubMed
  9. Gastrointest Endosc. 2012 Dec;76(6):1104-12 - PubMed
  10. Opt Lett. 2009 Jun 1;34(11):1615-7 - PubMed
  11. Ann Biomed Eng. 2016 Mar;44(3):667-79 - PubMed
  12. Curr Opin Biotechnol. 2009 Feb;20(1):111-8 - PubMed
  13. N Engl J Med. 2009 May 28;360(22):2277-88 - PubMed
  14. J Biomed Opt. 2008 Jan-Feb;13(1):014014 - PubMed
  15. Opt Lett. 2014 Apr 1;39(7):2016-9 - PubMed
  16. Endoscopy. 2010 Oct;42(10):781-9 - PubMed
  17. Lasers Surg Med. 2006 Apr;38(4):305-13 - PubMed
  18. Biomed Opt Express. 2015 Mar 05;6(4):1146-63 - PubMed
  19. Sci Rep. 2015 Nov 27;5:17325 - PubMed
  20. Quant Imaging Med Surg. 2015 Feb;5(1):118-24 - PubMed
  21. J Biomed Opt. 2008 Jul-Aug;13(4):044012 - PubMed
  22. Appl Opt. 1995 May 1;34(13):2362-6 - PubMed
  23. Am J Gastroenterol. 2009 Jun;104(6):1366-73 - PubMed
  24. Dis Esophagus. 2014 Apr;27(3):262-6 - PubMed
  25. Nat Med. 2002 Jul;8(7):757-60 - PubMed
  26. Gut. 2003 Apr;52(4):486-9 - PubMed
  27. J Biomed Opt. 2005 Nov-Dec;10(6):064033 - PubMed
  28. Science. 1991 Nov 22;254(5035):1178-81 - PubMed
  29. Gastrointest Endosc. 2012 Jul;76(1):32-40 - PubMed
  30. Phys Med Biol. 2010 Jan 7;55(1):191-206 - PubMed
  31. Am J Gastroenterol. 2011 Nov;106(11):1899-908; quiz 1909 - PubMed
  32. Biomed Opt Express. 2015 Apr 22;6(5):1828-43 - PubMed
  33. Dis Esophagus. 2016 Aug;29(6):505-12 - PubMed
  34. Nature. 2013 Sep 19;501(7467):338-45 - PubMed
  35. J Nucl Med. 2004 Oct;45(10 ):1776-83 - PubMed
  36. Opt Express. 2006 Mar 6;14(5):1878-87 - PubMed
  37. Invest Radiol. 2005 Jun;40(6):321-7 - PubMed
  38. Clin Gastroenterol Hepatol. 2006 Jan;4(1):38-43 - PubMed
  39. Gastrointest Endosc. 2000 Apr;51(4 Pt 1):467-74 - PubMed
  40. Gastroenterology. 2010 Nov;139(5):1472-80 - PubMed
  41. Phys Med Biol. 2011 Apr 21;56(8):N115-22 - PubMed
  42. Gastrointest Endosc. 2010 Sep;72(3):490-496.e1 - PubMed
  43. J Urol. 2005 Dec;174(6):2376-81 - PubMed
  44. Biophys J. 1998 Oct;75(4):2015-24 - PubMed
  45. Opt Lett. 2001 May 15;26(10):701-3 - PubMed
  46. Nat Med. 1995 Sep;1(9):970-2 - PubMed
  47. Curr Opin Gastroenterol. 2013 Jul;29(4):454-9 - PubMed
  48. Opt Express. 2007 Dec 24;15(26):17827-41 - PubMed
  49. Nat Med. 2013 Feb;19(2):238-40 - PubMed
  50. Opt Lett. 2003 Dec 15;28(24):2485-7 - PubMed
  51. Gastroenterology. 2001 Jan;120(1):7-12 - PubMed
  52. Science. 1997 Jun 27;276(5321):2037-9 - PubMed
  53. Endoscopy. 2007 Jul;39(7):599-605 - PubMed
  54. Acad Radiol. 2014 Feb;21(2):271-80 - PubMed
  55. Appl Opt. 2004 Jan 1;43(1):113-21 - PubMed
  56. Am J Surg Pathol. 2007 Mar;31(3):403-9 - PubMed
  57. J Biomed Opt. 2009 May-Jun;14(3):034040 - PubMed
  58. Gastrointest Endosc. 2003 Aug;58(2):196-202 - PubMed
  59. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3308-13 - PubMed
  60. Opt Express. 2009 Oct 26;17(22):20178-90 - PubMed
  61. Am J Physiol Renal Physiol. 2007 Jun;292(6):F1873-80 - PubMed
  62. Neurophotonics. 2017 Jan;4(1):011009 - PubMed
  63. Clin Cancer Res. 2008 Apr 1;14(7):2006-11 - PubMed
  64. Opt Express. 2011 Dec 19;19(27):26283-94 - PubMed
  65. Opt Express. 2010 Nov 8;18(23):23676-90 - PubMed
  66. Opt Express. 2008 Sep 29;16(20):15847-62 - PubMed
  67. Biomed Opt Express. 2012 Jul 1;3(7):1701-12 - PubMed
  68. Sci Rep. 2016 Apr 29;6:25269 - PubMed
  69. Opt Lett. 2000 Dec 15;25(24):1777-9 - PubMed
  70. Gastrointest Endosc. 2005 Dec;62(6):825-31 - PubMed
  71. Gastroenterology. 2002 Feb;122(2):406-14 - PubMed
  72. Nat Med. 2011 Sep 18;17(10):1315-9 - PubMed
  73. Opt Express. 1997 Dec 22;1(13):432-40 - PubMed
  74. Opt Lett. 2004 Jul 15;29(14):1650-2 - PubMed

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