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RU Ibarra, JS Edwards, BO Palsson - Nature, 2002 - nature.com

Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth.

k-12

Edwards, Palsson

GSID: nVsDZZLJhqcJ

Excerpt

… coli K-12 on several substrates (acetate, succinate, malate, glucose and glycerol). All … coli K-12 on malate was predicted a priori by using PPP. The results for growth with malate … coli K-12 MG1655 annotated genome sequence and the biochemical literature were used to …

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