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Tamagnone L, Merida A, Parr A, et al. The AmMYB308 and AmMYB330 transcription factors from antirrhinum regulate phenylpropanoid and lignin biosynthesis in transgenic tobacco . Plant Cell. 1998;10(2):135-54doi: 10.1105/tpc.10.2.135.
Tamagnone, L., Merida, A., Parr, A., Mackay, S., Culianez-Macia, F. A., Roberts, K., & Martin, C. (1998). The AmMYB308 and AmMYB330 transcription factors from antirrhinum regulate phenylpropanoid and lignin biosynthesis in transgenic tobacco . The Plant cell, 10(2), 135-54. https://doi.org/10.1105/tpc.10.2.135
Tamagnone, et al. "The AmMYB308 and AmMYB330 transcription factors from antirrhinum regulate phenylpropanoid and lignin biosynthesis in transgenic tobacco ." The Plant cell vol. 10,2 (1998): 135-54. doi: https://doi.org/10.1105/tpc.10.2.135
Tamagnone L, Merida A, Parr A, Mackay S, Culianez-Macia FA, Roberts K, Martin C. The AmMYB308 and AmMYB330 transcription factors from antirrhinum regulate phenylpropanoid and lignin biosynthesis in transgenic tobacco . Plant Cell. 1998 Feb;10(2):135-54. doi: 10.1105/tpc.10.2.135. PMID: 9490739; PMCID: PMC143979.
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Plant Cell. 1998 Feb;10(2):135-54. doi: 10.1105/tpc.10.2.135.

The AmMYB308 and AmMYB330 transcription factors from antirrhinum regulate phenylpropanoid and lignin biosynthesis in transgenic tobacco .

The Plant cell

Tamagnone, Merida, Parr, Mackay, Culianez-Macia, Roberts, Martin

Affiliations

  1. John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, United Kingdom.

PMID: 9490739 PMCID: PMC143979 DOI: 10.1105/tpc.10.2.135
Free PMC Article

Abstract

MYB-related transcription factors are known to regulate different branches of flavonoid metabolism in plants and are believed to play wider roles in the regulation of phenylpropanoid metabolism in general. Here, we demonstrate that overexpression of two MYB genes from Antirrhinum represses phenolic acid metabolism and lignin biosynthesis in transgenic tobacco plants. The inhibition of this branch of phenylpropanoid metabolism appears to be specific to AmMYB308 and AmMYB330, suggesting that they recognize their normal target genes in these transgenic plants. Experiments with yeast indicate that AmMYB308 can act as a very weak transcriptional activator so that overexpression may competitively inhibit the activity of stronger activators recognizing the same target motifs. The effects of the transcription factors on inhibition of phenolic acid metabolism resulted in complex modifications of the growth and development of the transgenic plants. The inhibition of monolignol production resulted in plants with at least 17% less lignin in their vascular tissue. This reduction is of importance when designing strategies for the genetic modification of woody crops.

Cited by

Li M, Li Y, Guo L, Gong N, Pang Y, Jiang W, Liu Y, Jiang X, Zhao L, Wang Y, Xie DY, Gao L, Xia T.
Front Plant Sci. 2017 Jun 12;8:943. doi: 10.3389/fpls.2017.00943. eCollection 2017.
PMID: 28659938

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