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Showing 13 to 24 of 220 entries
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Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production.

Canadian journal of physiology and pharmacology

Ayyash A, Holloway AC.
PMID: 33517848
Can J Physiol Pharmacol. 2021 Sep;99(9):983-988. doi: 10.1139/cjpp-2020-0721. Epub 2021 Jan 30.

Fluoxetine, a commonly prescribed selective serotonin reuptake inhibitor antidepressant, has been shown to increase hepatic lipid accumulation, a key factor in the development of nonalcoholic fatty liver disease. Interestingly, fluoxetine has also been reported to increase peripheral serotonin synthesis....

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Ayyash A, Holloway AC. Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production. Can J Physiol Pharmacol. 2021;99(9):983-988doi: 10.1139/cjpp-2020-0721.
Ayyash, A., & Holloway, A. C. (2021). Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production. Canadian journal of physiology and pharmacology, 99(9), 983-988. https://doi.org/10.1139/cjpp-2020-0721
Ayyash, Ahmed, and Holloway, Alison C. "Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production." Canadian journal of physiology and pharmacology vol. 99,9 (2021): 983-988. doi: https://doi.org/10.1139/cjpp-2020-0721
Ayyash A, Holloway AC. Fluoxetine-induced hepatic lipid accumulation is linked to elevated serotonin production. Can J Physiol Pharmacol. 2021 Sep;99(9):983-988. doi: 10.1139/cjpp-2020-0721. Epub 2021 Jan 30. PMID: 33517848.
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Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway.

Canadian journal of physiology and pharmacology

Liu Q, Zheng B, Zhang Y, Huang W, Hong Q, Meng Y.
PMID: 33517849
Can J Physiol Pharmacol. 2021 Sep;99(9):885-893. doi: 10.1139/cjpp-2020-0662. Epub 2021 Jan 30.

Alamandine (ALA) and its receptor MrgD were recently identified as components of the renin-angiotensin system, which confer protection against cardio-fibrosis and renal-fibrosis; however, the effects of ALA on pulmonary fibrosis are unknown. This study was designed to serve two...

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Liu Q, Zheng B, Zhang Y, et al. Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway. Can J Physiol Pharmacol. 2021;99(9):885-893doi: 10.1139/cjpp-2020-0662.
Liu, Q., Zheng, B., Zhang, Y., Huang, W., Hong, Q., & Meng, Y. (2021). Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway. Canadian journal of physiology and pharmacology, 99(9), 885-893. https://doi.org/10.1139/cjpp-2020-0662
Liu, Qingxia, et al. "Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway." Canadian journal of physiology and pharmacology vol. 99,9 (2021): 885-893. doi: https://doi.org/10.1139/cjpp-2020-0662
Liu Q, Zheng B, Zhang Y, Huang W, Hong Q, Meng Y. Alamandine via MrgD receptor attenuates pulmonary fibrosis via NOX4 and autophagy pathway. Can J Physiol Pharmacol. 2021 Sep;99(9):885-893. doi: 10.1139/cjpp-2020-0662. Epub 2021 Jan 30. PMID: 33517849.
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Acute and chronic metabolic effects of carvedilol in high-fructose, high-fat diet-fed mice: implication of β-arrestin2 pathway.

Canadian journal of physiology and pharmacology

Ahmed HMS, Mohamed SG, Ibrahim WS, Rezk AM, Mahmoud AAA, Mahmoud MF, Ibrahim IAAE.
PMID: 34570983
Can J Physiol Pharmacol. 2021 Sep 27;1-10. doi: 10.1139/cjpp-2021-0299. Epub 2021 Sep 27.

We aimed to investigate the acute and chronic effects of carvedilol on insulin resistance in high-fructose, high-fat diet (HFrHFD) - fed mice and the implication of the β-arrestin2 pathway. The acute effect of carvedilol (10 mg/kg, i.p.) on glucose...

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Ahmed HMS, Mohamed SG, Ibrahim WS, et al. Acute and chronic metabolic effects of carvedilol in high-fructose, high-fat diet-fed mice: implication of β-arrestin2 pathway. Can J Physiol Pharmacol. 2021;1-10doi: 10.1139/cjpp-2021-0299.
Ahmed, H. M. S., Mohamed, S. G., Ibrahim, W. S., Rezk, A. M., Mahmoud, A. A. A., Mahmoud, M. F., & Ibrahim, I. A. A. E. (2021). Acute and chronic metabolic effects of carvedilol in high-fructose, high-fat diet-fed mice: implication of β-arrestin2 pathway. Canadian journal of physiology and pharmacology, 1-10. https://doi.org/10.1139/cjpp-2021-0299
Ahmed, Hoda M S, et al. "Acute and chronic metabolic effects of carvedilol in high-fructose, high-fat diet-fed mice: implication of β-arrestin2 pathway." Canadian journal of physiology and pharmacology vol. (2021): 1-10. doi: https://doi.org/10.1139/cjpp-2021-0299
Ahmed HMS, Mohamed SG, Ibrahim WS, Rezk AM, Mahmoud AAA, Mahmoud MF, Ibrahim IAAE. Acute and chronic metabolic effects of carvedilol in high-fructose, high-fat diet-fed mice: implication of β-arrestin2 pathway. Can J Physiol Pharmacol. 2021 Sep 27;1-10. doi: 10.1139/cjpp-2021-0299. Epub 2021 Sep 27. PMID: 34570983.
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Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation.

Canadian journal of physiology and pharmacology

Wang Y, Wu W, Zhang J, Sun J, Wang J, Hang Y, Wang Q, Duan P.
PMID: 34570990
Can J Physiol Pharmacol. 2021 Sep 27;1-8. doi: 10.1139/cjpp-2021-0298. Epub 2021 Sep 27.

The purpose of this study was to evaluate the effect of intracutaneous pyonex on analgesia and sedation in critically ill patients who underwent mechanical ventilation. A total of 88 critically ill patients were divided into a control group and...

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Wang Y, Wu W, Zhang J, et al. Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation. Can J Physiol Pharmacol. 2021;1-8doi: 10.1139/cjpp-2021-0298.
Wang, Y., Wu, W., Zhang, J., Sun, J., Wang, J., Hang, Y., Wang, Q., & Duan, P. (2021). Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation. Canadian journal of physiology and pharmacology, 1-8. https://doi.org/10.1139/cjpp-2021-0298
Wang, Yuanyuan, et al. "Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation." Canadian journal of physiology and pharmacology vol. (2021): 1-8. doi: https://doi.org/10.1139/cjpp-2021-0298
Wang Y, Wu W, Zhang J, Sun J, Wang J, Hang Y, Wang Q, Duan P. Effect of intracutaneous pyonex on analgesia and sedation in critically ill patients with mechanical ventilation. Can J Physiol Pharmacol. 2021 Sep 27;1-8. doi: 10.1139/cjpp-2021-0298. Epub 2021 Sep 27. PMID: 34570990.
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4,4'-Dichloro-diphenyl diselenide modulated oxidative stress that differently affected peripheral tissues in streptozotocin-exposed mice.

Canadian journal of physiology and pharmacology

Marques LS, Zborowski VA, Heck SO, Fulco BCW, Nogueira CW.
PMID: 33861646
Can J Physiol Pharmacol. 2021 Sep;99(9):943-951. doi: 10.1139/cjpp-2020-0652. Epub 2021 Apr 16.

Streptozotocin (STZ) is a substance used experimentally to induce a diabetes model, a metabolic disease associated with oxidative tissue damage. This study evaluated if 4-4'-dichloro-diphenyl diselenide (

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Marques LS, Zborowski VA, Heck SO, et al. 4,4'-Dichloro-diphenyl diselenide modulated oxidative stress that differently affected peripheral tissues in streptozotocin-exposed mice. Can J Physiol Pharmacol. 2021;99(9):943-951doi: 10.1139/cjpp-2020-0652.
Marques, L. S., Zborowski, V. A., Heck, S. O., Fulco, B. C. W., & Nogueira, C. W. (2021). 4,4'-Dichloro-diphenyl diselenide modulated oxidative stress that differently affected peripheral tissues in streptozotocin-exposed mice. Canadian journal of physiology and pharmacology, 99(9), 943-951. https://doi.org/10.1139/cjpp-2020-0652
Marques, Luiza S, et al. "4,4'-Dichloro-diphenyl diselenide modulated oxidative stress that differently affected peripheral tissues in streptozotocin-exposed mice." Canadian journal of physiology and pharmacology vol. 99,9 (2021): 943-951. doi: https://doi.org/10.1139/cjpp-2020-0652
Marques LS, Zborowski VA, Heck SO, Fulco BCW, Nogueira CW. 4,4'-Dichloro-diphenyl diselenide modulated oxidative stress that differently affected peripheral tissues in streptozotocin-exposed mice. Can J Physiol Pharmacol. 2021 Sep;99(9):943-951. doi: 10.1139/cjpp-2020-0652. Epub 2021 Apr 16. PMID: 33861646.
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Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats.

Canadian journal of physiology and pharmacology

Rodríguez-Núñez I, Pontes RB, Romero F, Campos RR.
PMID: 33290163
Can J Physiol Pharmacol. 2021 Aug;99(8):786-794. doi: 10.1139/cjpp-2020-0381. Epub 2020 Dec 08.

Chronic nicotine exposure may increase cardiovascular risk by impairing the cardiac autonomic function. Besides, physical exercise (PE) has shown to improve cardiovascular health. Thus, we aimed to investigate the effects of PE on baroreflex sensitivity (BRS), heart rate variability...

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Rodríguez-Núñez I, Pontes RB, Romero F, et al. Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats. Can J Physiol Pharmacol. 2020;99(8):786-794doi: 10.1139/cjpp-2020-0381.
Rodríguez-Núñez, I., Pontes, R. B., Romero, F., & Campos, R. R. (2021). Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats. Canadian journal of physiology and pharmacology, 99(8), 786-794. https://doi.org/10.1139/cjpp-2020-0381
Rodríguez-Núñez, Iván, et al. "Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats." Canadian journal of physiology and pharmacology vol. 99,8 (2021): 786-794. doi: https://doi.org/10.1139/cjpp-2020-0381
Rodríguez-Núñez I, Pontes RB, Romero F, Campos RR. Effects of physical exercise on baroreflex sensitivity and renal sympathetic nerve activity in chronic nicotine-treated rats. Can J Physiol Pharmacol. 2021 Aug;99(8):786-794. doi: 10.1139/cjpp-2020-0381. Epub 2020 Dec 08. PMID: 33290163.
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Intracellular pH regulation and the acid delusion.

Canadian journal of physiology and pharmacology

Magder S, Magder A, Samoukovic G.
PMID: 33356898
Can J Physiol Pharmacol. 2021 Jun;99(6):561-576. doi: 10.1139/cjpp-2020-0631. Epub 2020 Dec 23.

The hydrogen ion concentration ([H

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Magder S, Magder A, Samoukovic G. Intracellular pH regulation and the acid delusion. Can J Physiol Pharmacol. 2020;99(6):561-576doi: 10.1139/cjpp-2020-0631.
Magder, S., Magder, A., & Samoukovic, G. (2021). Intracellular pH regulation and the acid delusion. Canadian journal of physiology and pharmacology, 99(6), 561-576. https://doi.org/10.1139/cjpp-2020-0631
Magder, Sheldon, et al. "Intracellular pH regulation and the acid delusion." Canadian journal of physiology and pharmacology vol. 99,6 (2021): 561-576. doi: https://doi.org/10.1139/cjpp-2020-0631
Magder S, Magder A, Samoukovic G. Intracellular pH regulation and the acid delusion. Can J Physiol Pharmacol. 2021 Jun;99(6):561-576. doi: 10.1139/cjpp-2020-0631. Epub 2020 Dec 23. PMID: 33356898.
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Colchicine attenuates renal ischemia-reperfusion-induced liver damage: implication of TLR4/NF-κB, TGF-β, and .

Canadian journal of physiology and pharmacology

Awad AS, Elariny HA, Sallam AS.
PMID: 34411492
Can J Physiol Pharmacol. 2021 Aug 19;1-7. doi: 10.1139/cjpp-2021-0007. Epub 2021 Aug 19.

Ischemia-reperfusion injury (IRI) is typically associated with a vigorous inflammatory and oxidative stress response to hypoxia and reperfusion that disturbs the function of the organ. The remote effects of renal IRI on the liver, however, require further study. Renal...

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Awad AS, Elariny HA, Sallam AS. Colchicine attenuates renal ischemia-reperfusion-induced liver damage: implication of TLR4/NF-κB, TGF-β, and . Can J Physiol Pharmacol. 2021;1-7doi: 10.1139/cjpp-2021-0007.
Awad, A. S., Elariny, H. A., & Sallam, A. S. (2021). Colchicine attenuates renal ischemia-reperfusion-induced liver damage: implication of TLR4/NF-κB, TGF-β, and . Canadian journal of physiology and pharmacology, 1-7. https://doi.org/10.1139/cjpp-2021-0007
Awad, Azza Sayed, et al. "Colchicine attenuates renal ischemia-reperfusion-induced liver damage: implication of TLR4/NF-κB, TGF-β, and ." Canadian journal of physiology and pharmacology vol. (2021): 1-7. doi: https://doi.org/10.1139/cjpp-2021-0007
Awad AS, Elariny HA, Sallam AS. Colchicine attenuates renal ischemia-reperfusion-induced liver damage: implication of TLR4/NF-κB, TGF-β, and . Can J Physiol Pharmacol. 2021 Aug 19;1-7. doi: 10.1139/cjpp-2021-0007. Epub 2021 Aug 19. PMID: 34411492.
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Role of pregnancy on insulin-induced vasorelaxation: the influence of angiotensin II receptors.

Canadian journal of physiology and pharmacology

Rodríguez-Reyes B, Tufiño C, López Mayorga RM, Mera Jiménez E, Bobadilla Lugo RA.
PMID: 33857388
Can J Physiol Pharmacol. 2021 Oct;99(10):1026-1035. doi: 10.1139/cjpp-2021-0057. Epub 2021 Apr 15.

Insulin resistance is a feature of pregnancy and is associated with increased levels of angiotensin II (Ang II) and insulin. Therefore, pregnancy may change insulin-induced vasodilation through changes in Ang II receptors. Insulin-induced vasorelaxation was evaluated in phenylephrine-precontracted aortic...

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Rodríguez-Reyes B, Tufiño C, López Mayorga RM, et al. Role of pregnancy on insulin-induced vasorelaxation: the influence of angiotensin II receptors. Can J Physiol Pharmacol. 2021;99(10):1026-1035doi: 10.1139/cjpp-2021-0057.
Rodríguez-Reyes, B., Tufiño, C., López Mayorga, R. M., Mera Jiménez, E., & Bobadilla Lugo, R. A. (2021). Role of pregnancy on insulin-induced vasorelaxation: the influence of angiotensin II receptors. Canadian journal of physiology and pharmacology, 99(10), 1026-1035. https://doi.org/10.1139/cjpp-2021-0057
Rodríguez-Reyes, Betzabel, et al. "Role of pregnancy on insulin-induced vasorelaxation: the influence of angiotensin II receptors." Canadian journal of physiology and pharmacology vol. 99,10 (2021): 1026-1035. doi: https://doi.org/10.1139/cjpp-2021-0057
Rodríguez-Reyes B, Tufiño C, López Mayorga RM, Mera Jiménez E, Bobadilla Lugo RA. Role of pregnancy on insulin-induced vasorelaxation: the influence of angiotensin II receptors. Can J Physiol Pharmacol. 2021 Oct;99(10):1026-1035. doi: 10.1139/cjpp-2021-0057. Epub 2021 Apr 15. PMID: 33857388.
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Exchange proteins directly activated by cAMP mediate cardiac repolarization and arrhythmogenesis during chronic heart failure.

Canadian journal of physiology and pharmacology

Zhu D, Zhu R, Zhou X, Shi E, Zhang X, Zhou Z, Li D, Zou J, Wang Y.
PMID: 33175603
Can J Physiol Pharmacol. 2021 Jul;99(7):729-736. doi: 10.1139/cjpp-2020-0122. Epub 2020 Nov 11.

Most sudden cardiac death in chronic heart failure (CHF) is caused by malignant ventricular arrhythmia (VA); however, the molecular mechanism remains unclear. This study aims to explore the effect of exchange proteins directly activated by cAMP (Epac) on VA...

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Zhu D, Zhu R, Zhou X, et al. Exchange proteins directly activated by cAMP mediate cardiac repolarization and arrhythmogenesis during chronic heart failure. Can J Physiol Pharmacol. 2020;99(7):729-736doi: 10.1139/cjpp-2020-0122.
Zhu, D., Zhu, R., Zhou, X., Shi, E., Zhang, X., Zhou, Z., Li, D., Zou, J., & Wang, Y. (2021). Exchange proteins directly activated by cAMP mediate cardiac repolarization and arrhythmogenesis during chronic heart failure. Canadian journal of physiology and pharmacology, 99(7), 729-736. https://doi.org/10.1139/cjpp-2020-0122
Zhu, Didi, et al. "Exchange proteins directly activated by cAMP mediate cardiac repolarization and arrhythmogenesis during chronic heart failure." Canadian journal of physiology and pharmacology vol. 99,7 (2021): 729-736. doi: https://doi.org/10.1139/cjpp-2020-0122
Zhu D, Zhu R, Zhou X, Shi E, Zhang X, Zhou Z, Li D, Zou J, Wang Y. Exchange proteins directly activated by cAMP mediate cardiac repolarization and arrhythmogenesis during chronic heart failure. Can J Physiol Pharmacol. 2021 Jul;99(7):729-736. doi: 10.1139/cjpp-2020-0122. Epub 2020 Nov 11. PMID: 33175603.
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Neuromuscular electrical stimulation but not photobiomodulation therapy improves cardiovascular parameters of rats with heart failure.

Canadian journal of physiology and pharmacology

Capalonga L, de Araujo CLP, Hentschke VS, Rossato DD, Quagliotto E, Becker T, Rigatto K, Ferraresi C, Parizotto NA, Dal Lago P.
PMID: 33211546
Can J Physiol Pharmacol. 2021 Jul;99(7):720-728. doi: 10.1139/cjpp-2020-0339. Epub 2020 Nov 19.

The aim of the present study was to analyze the effect of neuromuscular electrical stimulation (NMES) and photobiomodulation (PBMT) on the cardiovascular parameters, hemodynamic function, arterial baroreflex sensitivity (BRS), and autonomic balance (ANS) of rats with heart failure (HF)....

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Capalonga L, de Araujo CLP, Hentschke VS, et al. Neuromuscular electrical stimulation but not photobiomodulation therapy improves cardiovascular parameters of rats with heart failure. Can J Physiol Pharmacol. 2020;99(7):720-728doi: 10.1139/cjpp-2020-0339.
Capalonga, L., de Araujo, C. L. P., Hentschke, V. S., Rossato, D. D., Quagliotto, E., Becker, T., Rigatto, K., Ferraresi, C., Parizotto, N. A., & Dal Lago, P. (2021). Neuromuscular electrical stimulation but not photobiomodulation therapy improves cardiovascular parameters of rats with heart failure. Canadian journal of physiology and pharmacology, 99(7), 720-728. https://doi.org/10.1139/cjpp-2020-0339
Capalonga, Lucas, et al. "Neuromuscular electrical stimulation but not photobiomodulation therapy improves cardiovascular parameters of rats with heart failure." Canadian journal of physiology and pharmacology vol. 99,7 (2021): 720-728. doi: https://doi.org/10.1139/cjpp-2020-0339
Capalonga L, de Araujo CLP, Hentschke VS, Rossato DD, Quagliotto E, Becker T, Rigatto K, Ferraresi C, Parizotto NA, Dal Lago P. Neuromuscular electrical stimulation but not photobiomodulation therapy improves cardiovascular parameters of rats with heart failure. Can J Physiol Pharmacol. 2021 Jul;99(7):720-728. doi: 10.1139/cjpp-2020-0339. Epub 2020 Nov 19. PMID: 33211546.
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Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation.

Canadian journal of physiology and pharmacology

Butkevich IP, Mikhailenko VA, Vershinina EA.
PMID: 33186073
Can J Physiol Pharmacol. 2021 Jun;99(6):609-618. doi: 10.1139/cjpp-2020-0307. Epub 2020 Nov 13.

Previously, we have shown that the administration of a selective serotonin reuptake inhibitor fluoxetine or a 5-HT1A receptor agonist buspirone to stressed rats during gestation causes in the offspring alleviation of formalin-induced pain, strengthened by prenatal stress. We have...

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Butkevich IP, Mikhailenko VA, Vershinina EA. Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation. Can J Physiol Pharmacol. 2020;99(6):609-618doi: 10.1139/cjpp-2020-0307.
Butkevich, I. P., Mikhailenko, V. A., & Vershinina, E. A. (2021). Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation. Canadian journal of physiology and pharmacology, 99(6), 609-618. https://doi.org/10.1139/cjpp-2020-0307
Butkevich, Irina P, et al. "Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation." Canadian journal of physiology and pharmacology vol. 99,6 (2021): 609-618. doi: https://doi.org/10.1139/cjpp-2020-0307
Butkevich IP, Mikhailenko VA, Vershinina EA. Neonatal pain modulates in adolescent rats the antinociceptive effects of fluoxetine and buspirone administrated to their depressive dams during gestation. Can J Physiol Pharmacol. 2021 Jun;99(6):609-618. doi: 10.1139/cjpp-2020-0307. Epub 2020 Nov 13. PMID: 33186073.
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Showing 13 to 24 of 220 entries