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Showing 13 to 24 of 1106 entries
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Dynamic mechanical allodynia following finger amputation: Unexpected skin hyperinnervation.

World journal of clinical cases

Buonocore M, Gagliano MC, Bonezzi C.
PMID: 24303500
World J Clin Cases. 2013 Sep 16;1(6):197-201. doi: 10.12998/wjcc.v1.i6.197.

The development of chronic pain after amputations is not an uncommon event. In some cases the most disabling problem is represented by the symptom called dynamic mechanical allodynia, characterized by the painful sensation evoked by gently stroking the skin....

The synthetic potential of immobilised cells of Capsicum frutescens Mill cv. annuum.

Planta

Lindsey K, Yeoman MM.
PMID: 24253265
Planta. 1984 Dec;162(6):495-501. doi: 10.1007/BF00399914.

Cells of Capsicum frutescens Mill. cv. annuum, immobilised in reticulate polyurethane foam, produced higher yields of capsaicin, the pungent principle of Chilli pepper fruits, than did freely-suspended cells, when batch-cultured in a medium conducive to culture growth. In the...

Antimicrobial and Anti-Virulence Activity of Capsaicin Against Erythromycin-Resistant, Cell-Invasive Group A Streptococci.

Frontiers in microbiology

Marini E, Magi G, Mingoia M, Pugnaloni A, Facinelli B.
PMID: 26617603
Front Microbiol. 2015 Nov 13;6:1281. doi: 10.3389/fmicb.2015.01281. eCollection 2015.

Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is the active component of Capsicum plants (chili peppers), which are grown as food and for medicinal purposes since ancient times, and is responsible for the pungency of their fruit. Besides its multiple pharmacological and physiological properties...

Sensitive detection of capsaicinoids using a surface plasmon resonance sensor with anti-homovanillic Acid polyclonal antibodies.

Biosensors

Nakamura S, Yatabe R, Onodera T, Toko K.
PMID: 25586413
Biosensors (Basel). 2013 Nov 13;3(4):374-84. doi: 10.3390/bios3040374.

Recently, highly functional biosensors have been developed in preparation for possible large-scale terrorist attacks using chemical warfare agents. Practically applicable sensors are required to have various abilities, such as high portability and operability, the capability of performing rapid and...

Juvenile obesity aggravates disease severity in a rat model of atopic dermatitis.

Allergy, asthma & immunology research

Jeong KY, Lee J, Li C, Han T, Lee SB, Lee H, Back SK, Na HS.
PMID: 25553265
Allergy Asthma Immunol Res. 2015 Jan;7(1):69-75. doi: 10.4168/aair.2015.7.1.69. Epub 2014 Jul 09.

PURPOSE: There is increasing epidemiological evidence of an association between childhood obesity and atopic dermatitis, but little is known about the underlying mechanism(s). In the present study, we used a rat model of atopic dermatitis to assess whether juvenile...

Synthesis and Pharmacological Properties of Novel Esters Based on Monoterpenoids and Glycine.

Pharmaceuticals (Basel, Switzerland)

Nesterkina M, Kravchenko I.
PMID: 28524111
Pharmaceuticals (Basel). 2017 May 18;10(2). doi: 10.3390/ph10020047.

Esters based on mono- and bicyclic terpenoids with glycine have been synthesized via Steglich esterification and characterized by ¹H-NMR, IR, and mass spectral studies. Their analgesic and anti-inflammatory activities were investigated after transdermal delivery on models of formalin, capsaicin,...

Correction: Capsaicin Treatment Attenuates Cholangiocarcinoma Carcinogenesis.

PloS one

Wutka A, Palagani V, Barat S, Chen X, El Khatib M, Götze J, Belahmer H, Zender S, Bozko P, Malek NP, Plentz RR.
PMID: 27649309
PLoS One. 2016 Sep 20;11(9):e0162673. doi: 10.1371/journal.pone.0162673. eCollection 2016.

[This corrects the article DOI: 10.1371/journal.pone.0095605.].

Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil.

Evidence-based complementary and alternative medicine : eCAM

Donald GR, Fernandes PD, Boylan F.
PMID: 27547225
Evid Based Complement Alternat Med. 2016;2016:3840398. doi: 10.1155/2016/3840398. Epub 2016 Jul 31.

Zanthoxylum piperitum DC. (ZP) is a traditional medicinal plant used mainly in countries from Asia such as Japan. This study aimed to investigate the antinociceptive effect of ZP essential oil (ZPEO). The major component present in the essential oil...

Relative efficacy of topical non-steroidal anti-inflammatory drugs and topical capsaicin in osteoarthritis: protocol for an individual patient data meta-analysis.

Systematic reviews

Persson MS, Fu Y, Bhattacharya A, Goh SL, van Middelkoop M, Bierma-Zeinstra SM, Walsh D, Doherty M, Zhang W.
PMID: 27686859
Syst Rev. 2016 Sep 29;5(1):165. doi: 10.1186/s13643-016-0348-8.

BACKGROUND: Pain is the most troubling issue to patients with osteoarthritis (OA), yet current pharmacological treatments offer only small-to-moderate pain reduction. Current guidelines therefore emphasise the need to identify predictors of treatment response. In line with these recommendations, an...

Central Antinociceptive and Mechanism of Action of Pereskia bleo Kunth Leaves Crude Extract, Fractions, and Isolated Compounds.

Evidence-based complementary and alternative medicine : eCAM

Guilhon CC, Abdul Wahab IR, Boylan F, Fernandes PD.
PMID: 26273315
Evid Based Complement Alternat Med. 2015;2015:915927. doi: 10.1155/2015/915927. Epub 2015 Jul 27.

Pereskia bleo (Kunth) DC. (Cactaceae) is a plant commonly used in popular medicine in Malaysia. In this work, we evaluate the antinociceptive effect of P. bleo leaf extracts and isolated compounds in central antinociceptive model. Ethanol extract (E), hexane...

In-vitro analysis of selective nutraceuticals binding to human transcription factors through computer aided molecular docking predictions.

Bioinformation

Teimouri M, Junaid M, Saleem S, Khan A, Ali A.
PMID: 28246465
Bioinformation. 2016 Oct 17;12(7):354-358. doi: 10.6026/97320630012354. eCollection 2016.

The contest of cancer couldn't be completed without novel drug with novel modes of action, improved efficacy and acceptable pharmacokinetic properties. Transcription factors are attractive targets to develop anti-cancerous drugs. 6-Gingerol, Anethol analogues, Capsaicinoids, Curcumin, Dibenzoylmethane, Diosgenin, Eugenol, Gambogic...

Capsaicin induces immunogenic cell death in human osteosarcoma cells.

Experimental and therapeutic medicine

Jin T, Wu H, Wang Y, Peng H.
PMID: 27446273
Exp Ther Med. 2016 Aug;12(2):765-770. doi: 10.3892/etm.2016.3368. Epub 2016 May 19.

Immunogenic cell death (ICD) is characterized by the early surface exposure of calreticulin (CRT). As a specific signaling molecule, CRT on the surface of apoptotic tumor cells mediates the recognition and phagocytosis of tumor cells by antigen presenting cells....

Showing 13 to 24 of 1106 entries