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Showing 13 to 24 of 1683 entries
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Clinical Relevance of Environmental Factors in the Pathogenesis of Autoimmune Thyroid Disease.

Endocrinology and metabolism (Seoul, Korea)

Wiersinga WM.
PMID: 27184015
Endocrinol Metab (Seoul). 2016 Jun;31(2):213-22. doi: 10.3803/EnM.2016.31.2.213. Epub 2016 May 13.

Genetic factors contribute for about 70% to 80% and environmental factors for about 20% to 30% to the pathogenesis of autoimmune thyroid disease (AITD). Relatives of AITD patients carry a risk to contract AITD themselves. The 5-year risk can...

Does Gender have an Influence on Platelet Function and the Efficacy of Oral Antiplatelet Therapy?.

Interventional cardiology clinics

Tantry US, Navarese EP, Gurbel PA.
PMID: 28582096
Interv Cardiol Clin. 2012 Apr;1(2):223-230. doi: 10.1016/j.iccl.2012.01.007. Epub 2012 Feb 11.

The underlying pathophysiology of ischemic complications during acute coronary syndrome involves thrombus generation at sites of plaque rupture and endothelial erosion, in which platelet activation and aggregation play major roles. This review discusses whether there are intrinsic differences in...

Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction.

Hormone molecular biology and clinical investigation

Labrie F.
PMID: 25961226
Horm Mol Biol Clin Investig. 2010 Dec 01;4(1):499-507. doi: 10.1515/HMBCI.2010.064.

BACKGROUND: Following complete cessation of estrogen secretion by the ovaries at menopause, all estrogens and practically all androgens are made from dehydroepiandro-sterone (DHEA) of adrenal/ovarian origin. Although being an inactive molecule itself, DHEA is transformed at various levels and...

Desmoid tumours: our experience of six cases and review of literature.

Journal of clinical and diagnostic research : JCDR

Kallam AR, Ramakrishna BV, Roy GK, Karthik KR.
PMID: 25478405
J Clin Diagn Res. 2014 Oct;8(10):NE01-4. doi: 10.7860/JCDR/2014/9610.5032. Epub 2014 Oct 20.

Desmoid tumours represent aggressive fibroblastic proliferation of the musculoaponeurotic structures commonly from the anterior abdominal wall. These tumours infiltrate locally, recur frequently but do not metastasize. Antecedent trauma, pregnancy and estrogens play a role in the etiopathogenesis of these...

Plant derived alternatives for hormone replacement therapy (HRT).

Hormone molecular biology and clinical investigation

Seidlova-Wuttke D, Jarry H, Wuttke W.
PMID: 25436745
Horm Mol Biol Clin Investig. 2013 Dec;16(1):35-45. doi: 10.1515/hmbci-2013-0024.

Abstract Hormone replacement therapy (HRT) has undisputable positive effects on climacteric complaints, in the bone and on body weight but also several undesired side effects. Therefore, plant-derived alternatives are currently promoted. Phytoestrogens - primarily the isoflavones genistein, daidzein and...

Measurement of androgen and estrogen concentrations in cord blood: accuracy, biological interpretation, and applications to understanding human behavioral development.

Frontiers in endocrinology

Hollier LP, Keelan JA, Hickey M, Maybery MT, Whitehouse AJ.
PMID: 24829559
Front Endocrinol (Lausanne). 2014 May 02;5:64. doi: 10.3389/fendo.2014.00064. eCollection 2014.

Accurately measuring hormone exposure during prenatal life presents a methodological challenge and there is currently no "gold standard" approach. Ideally, circulating fetal hormone levels would be measured at repeated time points during pregnancy. However, it is not currently possible...

Managing Prolactinomas during Pregnancy.

Frontiers in endocrinology

Almalki MH, Alzahrani S, Alshahrani F, Alsherbeni S, Almoharib O, Aljohani N, Almagamsi A.
PMID: 26074878
Front Endocrinol (Lausanne). 2015 May 26;6:85. doi: 10.3389/fendo.2015.00085. eCollection 2015.

Prolactinomas are the most prevalent functional benign pituitary tumors due to a pituitary micro- or macroadenoma. The majority of patients presents with infertility and gonadal dysfunction. A dopamine agonist (DA) (bromocriptine or cabergoline) is the treatment of choice that...

The role of colonic bacteria in the metabolism of the natural isoflavone daidzin to equol.

Metabolites

Rafii F.
PMID: 25594250
Metabolites. 2015 Jan 14;5(1):56-73. doi: 10.3390/metabo5010056.

Isoflavones are found in leguminous plants, especially soybeans. They have a structural similarity to natural estrogens, which enables them to bind to estrogen receptors and elicit biological activities similar to natural estrogens. They have been suggested to be beneficial...

Sex hormones affect neurotransmitters and shape the adult female brain during hormonal transition periods.

Frontiers in neuroscience

Barth C, Villringer A, Sacher J.
PMID: 25750611
Front Neurosci. 2015 Feb 20;9:37. doi: 10.3389/fnins.2015.00037. eCollection 2015.

Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic branching, myelination and other important mechanisms of neural plasticity. Here we review the evidence from animal experiments and human studies reporting interactions between sex hormones and the dominant neurotransmitters,...

The effects of Anethum graveolens essence on scopolamine-induced memory impairment in mice.

Research in pharmaceutical sciences

Mesripour A, Rafieian-Kopaei M, Bahrami B.
PMID: 27168754
Res Pharm Sci. 2016 Mar-Apr;11(2):145-51.

Since Anethum graveolens (Dill) has phytoestrogenic compounds and it is proven that estrogens exert beneficial effects on cognition; the aim of this study was to understand if this plant can improve memory performance. Male Balb/c mice weighing 25-30 g...

Intra-testicular signals regulate germ cell progression and production of qualitatively mature spermatozoa in vertebrates.

Frontiers in endocrinology

Meccariello R, Chianese R, Chioccarelli T, Ciaramella V, Fasano S, Pierantoni R, Cobellis G.
PMID: 24847312
Front Endocrinol (Lausanne). 2014 May 08;5:69. doi: 10.3389/fendo.2014.00069. eCollection 2014.

Spermatogenesis, a highly conserved process in vertebrates, is mainly under the hypothalamic-pituitary control, being regulated by the secretion of pituitary gonadotropins, follicle stimulating hormone, and luteinizing hormone, in response to stimulation exerted by gonadotropin releasing hormone from hypothalamic neurons....

Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development.

PeerJ

Pashay Ahi E, Walker BS, Lassiter CS, Jónsson ZO.
PMID: 27069811
PeerJ. 2016 Mar 31;4:e1878. doi: 10.7717/peerj.1878. eCollection 2016.

The development of craniofacial skeletal structures requires well-orchestrated tissue interactions controlled by distinct molecular signals. Disruptions in normal function of these molecular signals have been associated with a wide range of craniofacial malformations. A pathway mediated by estrogens is...

Showing 13 to 24 of 1683 entries