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Showing 13 to 24 of 435 entries
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Expression of Factor IX cDNA Introduced into Human Marrow Stromal Cells by Electroporation.

Hematology (Amsterdam, Netherlands)

Fouillard L, Matthews KE, Guinn BA, Branch DR, Keating A.
PMID: 27414078
Hematology. 1998;3(5):347-54. doi: 10.1080/10245332.1998.11746408.

Management of hemophilia B with gene therapy is an attractive and potentially feasible goal since stringent regulation of the recombinant protein is not required and low circulating levels may be sufficient to prevent symptoms. We are investigating the potential...

Trypanosoma cruzi Infection Induces Myocardial Nitric Oxide Synthase.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology

Huang Md H, Chan Md J, Wittner Md PhD M, Weiss Md Mph LM, Bacchi PhD J, Yarlett PhD N, Martinez Ba M, Morris Md PhD SA, Braunstein Bs VL, Factor Md SM, Tanowitz Md HB.
PMID: 25850327
Cardiovasc Pathol. 1997 May-Jun;6(3):161-6. doi: 10.1016/s1054-8807(96)00094-4.

Chagas' disease caused by Trypanosoma cruzi, is an important cause of myocarditis and cardiomyopathy. Acute and chronic infection is associated with myocardial dysfunction, including dysrhythmias, conduction disturbances, and congestive heart failure. Nitric oxide (NO) has been implicated in the...

Symptomatic Acquired Haemophilia Due to Circulating Antibodies Against Both Factor VIII and IX in a Non-haemophiliac Patient.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

Damodar S, Bhat P, Balasubramaniam S.
PMID: 25332547
Indian J Hematol Blood Transfus. 2014 Sep;30:90-2. doi: 10.1007/s12288-013-0270-3. Epub 2013 May 24.

Acquired haemophilia is a very rare condition, occurring in less than 2 per million populations. This condition is caused commonly by acquired antibodies against factor VIII and rarely by antibodies against factor IX. Here we describe an extremely rare...

Prevalence of factor IX inhibitors among patients with haemophilia B: results of a large-scale North American survey.

Haemophilia : the official journal of the World Federation of Hemophilia

Katz J.
PMID: 27213902
Haemophilia. 1996 Jan;2(1):28-31. doi: 10.1111/j.1365-2516.1996.tb00006.x.

This survey provides new information on the severity of factor IX deficiencies among patients being treated for haemophilia B and on the prevalence of factor IX inhibitors in this population. A questionnaire was sent to 150 haemophilia treatment centres...

Transient loss of vision as the presenting symptom of papillary fibroelastoma of aortic valve.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology

Shirani J, Bradlow JA, Metveyeva P, Losada M, Factor SM, Strom JA, Sisto D.
PMID: 25991541
Cardiovasc Pathol. 1997 Jul;6(4):237-40. doi: 10.1016/S1054-8807(96)00137-8.

Cardiac papillary fibroelastomas are benign endocardial papillomas. They may arise from atrial or ventricular endocardium but most commonly are located in cardiac valves. Their papillary structure, with loose, friable projections, results in a high tendency for embolism. Tumor fragments...

Reconfigurable directional lasing modes in cavities with generalized PT symmetry.

Physical review letters

Lee JM, Factor S, Lin Z, Vitebskiy I, Ellis FM, Kottos T.
PMID: 25014817
Phys Rev Lett. 2014 Jun 27;112(25):253902. doi: 10.1103/PhysRevLett.112.253902. Epub 2014 Jun 25.

We introduce a new family of generalized PT-symmetric cavities that involve gyrotropic elements and support reconfigurable unidirectional lasing modes. We derive conditions for which these modes exist and investigate a simple electronic circuit that experimentally demonstrates their feasibility in...

Recurrent Cerebral Venous Thrombosis Associated with Elevated Factor VIII.

Journal of clinical neurology (Seoul, Korea)

Kim MJ, Cho AH, No YJ, Kim HY, Kim JS.
PMID: 20396536
J Clin Neurol. 2006 Dec;2(4):286-9. doi: 10.3988/jcn.2006.2.4.286. Epub 2006 Dec 20.

Cerebral venous thrombosis (CVT) rarely recurs, and the factors associated with a recurrence remain unclear. Recently, however, elevated plasma coagulation factor VIII has been considered a factor related to recurrent venous thromboembolism. Here we report a patient who had...

Future therapies for the prevention and treatment of venous and arterial thrombosis.

Expert opinion on investigational drugs

McKean ML, Adelman SJ.
PMID: 15991961
Expert Opin Investig Drugs. 1998 May;7(5):687-90. doi: 10.1517/13543784.7.5.687.

The incidence of thrombosis as a complication of invasive surgery, in cancer patients, as a cause or complication of stroke, acute myocardial infarction (AMI), thrombolysis, unstable angina (UA) or angioplasty is substantial. To better serve this patient population in...

Clinical trials of add-on medications in Parkinson's disease: Efficacy versus usefulness.

Parkinsonism & related disorders

Hauser RA, Zesiewicz TA, Factor SA, Guttman M, Weiner WJ.
PMID: 18591048
Parkinsonism Relat Disord. 1997 Jan;3(1):1-6. doi: 10.1016/s1353-8020(96)00042-9.

Clinical trials designed to evaluate the efficacy of new anti-parkinsonian agents often employ an 'add-on' protocol in which patients with motor fluctuations on levodopa are randomized to receive active medication or placebo. Levodopa doses may not be increased, but...

Constitutive expression of human coagulating factor IX in HeLa cells by homologous recombination of the promoter.

Science in China. Series C, Life sciences

Yang X, Wang F, Wang Y, Lu D, Qiu X, Xue J.
PMID: 18763084
Sci China C Life Sci. 2001 Feb;44(1):18-24. doi: 10.1007/BF02882068.

Constitutive expression of hFIX protein in nonhepatocytes was studied. The gene targeting vector was constructed and transferred into HeLa cells. With the detection system of PCR, we demonstrated that the endogenoushFIX promoter was replaced with anhCMV promoter when targeted...

Optimal Immunofluorescent Staining for Human Factor IX and Infiltrating T Cells following Gene Therapy for Hemophilia B.

Journal of genetic syndromes & gene therapy

Rogers GL, Hoffman BE.
PMID: 23264888
J Genet Syndr Gene Ther. 2012 Aug 15; doi: 10.4172/2157-7412.s1-012.

Immunofluorescent imaging is a valuable tool for investigating the outcome of gene therapy within the transduced tissue. With a multi-labeling technique, it is possible to both characterize local expression of the transgene and to evaluate the severity of the...

Factorial structure of cognitive activity using a neuropsychological test battery.

Behavioural neurology

Ardila A, Rosselli M, Bateman JR.
PMID: 24487288
Behav Neurol. 1994;7(2):49-58. doi: 10.3233/BEN-1994-7202.

A general neuropsychological test battery was assembled and individually given to a 98-subject sample, aged 11-12 years old. The battery included some basic and common tests routinely used in the evaluation of language, memory, spatial abilities, concept formation, and...

Showing 13 to 24 of 435 entries