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Showing 13 to 24 of 2012 entries
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Biological Impact of Pd (II) Complexes: Synthesis, Spectral Characterization, In Vitro Anticancer, CT-DNA Binding, and Antioxidant Activities.

International journal of medicinal chemistry

Sharma NK, Ameta RK, Singh M.
PMID: 26989511
Int J Med Chem. 2016;2016:9245619. doi: 10.1155/2016/9245619. Epub 2016 Feb 16.

A new series of Pd (II) complexes of methyl substituted benzylamine ligands (BLs) has been synthesized and characterized via spectroscopic techniques such as UV/Vis. FTIR, LCMS, (1)H, and (13)C NMR. The UV/Vis study in DMSO, DMSO + water, and...

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Sharma NK, Ameta RK, Singh M. Biological Impact of Pd (II) Complexes: Synthesis, Spectral Characterization, In Vitro Anticancer, CT-DNA Binding, and Antioxidant Activities. Int J Med Chem. 2016;2016:9245619doi: 10.1155/2016/9245619.
Sharma, N. K., Ameta, R. K., & Singh, M. (2016). Biological Impact of Pd (II) Complexes: Synthesis, Spectral Characterization, In Vitro Anticancer, CT-DNA Binding, and Antioxidant Activities. International journal of medicinal chemistry, 20169245619. https://doi.org/10.1155/2016/9245619
Sharma, Nitin Kumar, et al. "Biological Impact of Pd (II) Complexes: Synthesis, Spectral Characterization, In Vitro Anticancer, CT-DNA Binding, and Antioxidant Activities." International journal of medicinal chemistry vol. 2016 (2016): 9245619. doi: https://doi.org/10.1155/2016/9245619
Sharma NK, Ameta RK, Singh M. Biological Impact of Pd (II) Complexes: Synthesis, Spectral Characterization, In Vitro Anticancer, CT-DNA Binding, and Antioxidant Activities. Int J Med Chem. 2016;2016:9245619. doi: 10.1155/2016/9245619. Epub 2016 Feb 16. PMID: 26989511; PMCID: PMC4771903.
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Comparative Study on the MDR Reversal Effects of Selected Chalcones.

International journal of medicinal chemistry

Ivanova AB, Batovska DI, Todorova IT, Stamboliyska BA, Serly J, Molnar J.
PMID: 27516904
Int J Med Chem. 2011;2011:530780. doi: 10.1155/2011/530780. Epub 2010 Dec 29.

Based on the structure of three previously established lead compounds, fifteen selected chalcones were synthesized and evaluated for their multidrug resistance (MDR) reversal activity on mouse lymphoma cells. The most active chalcones were stronger revertants than the positive control,...

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Ivanova AB, Batovska DI, Todorova IT, et al. Comparative Study on the MDR Reversal Effects of Selected Chalcones. Int J Med Chem. 2010;2011:530780doi: 10.1155/2011/530780.
Ivanova, A. B., Batovska, D. I., Todorova, I. T., Stamboliyska, B. A., Serly, J., & Molnar, J. (2011). Comparative Study on the MDR Reversal Effects of Selected Chalcones. International journal of medicinal chemistry, 2011530780. https://doi.org/10.1155/2011/530780
Ivanova, A B, et al. "Comparative Study on the MDR Reversal Effects of Selected Chalcones." International journal of medicinal chemistry vol. 2011 (2011): 530780. doi: https://doi.org/10.1155/2011/530780
Ivanova AB, Batovska DI, Todorova IT, Stamboliyska BA, Serly J, Molnar J. Comparative Study on the MDR Reversal Effects of Selected Chalcones. Int J Med Chem. 2011;2011:530780. doi: 10.1155/2011/530780. Epub 2010 Dec 29. PMID: 27516904; PMCID: PMC4970649.
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Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase.

Journal of medicinal chemistry

Sofia MJ, Chang W, Furman PA, Mosley RT, Ross BS.
PMID: 28339203
J Med Chem. 2017 Apr 13;60(7):3219. doi: 10.1021/acs.jmedchem.7b00427. Epub 2017 Mar 24.

No abstract available.

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Sofia MJ, Chang W, Furman PA, et al. Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase. J Med Chem. 2017;60(7):3219doi: 10.1021/acs.jmedchem.7b00427.
Sofia, M. J., Chang, W., Furman, P. A., Mosley, R. T., & Ross, B. S. (2017). Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase. Journal of medicinal chemistry, 60(7), 3219. https://doi.org/10.1021/acs.jmedchem.7b00427
Sofia, Michael J, et al. "Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase." Journal of medicinal chemistry vol. 60,7 (2017): 3219. doi: https://doi.org/10.1021/acs.jmedchem.7b00427
Sofia MJ, Chang W, Furman PA, Mosley RT, Ross BS. Correction to Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase. J Med Chem. 2017 Apr 13;60(7):3219. doi: 10.1021/acs.jmedchem.7b00427. Epub 2017 Mar 24. PMID: 28339203.
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Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.

Journal of medicinal chemistry

De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC.
PMID: 27487560
J Med Chem. 2016 Aug 25;59(16):7697. doi: 10.1021/acs.jmedchem.6b01091. Epub 2016 Aug 03.

No abstract available.

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De Petrocellis L, Arroyo FJ, Orlando P, et al. Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents. J Med Chem. 2016;59(16):7697doi: 10.1021/acs.jmedchem.6b01091.
De Petrocellis, L., Arroyo, F. J., Orlando, P., Schiano Moriello, A., Vitale, R. M., Amodeo, P., Sánchez, A., Roncero, C., Bianchini, G., Martín, M. A., López-Alvarado, P., & Menéndez, J. C. (2016). Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents. Journal of medicinal chemistry, 59(16), 7697. https://doi.org/10.1021/acs.jmedchem.6b01091
De Petrocellis, Luciano, et al. "Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents." Journal of medicinal chemistry vol. 59,16 (2016): 7697. doi: https://doi.org/10.1021/acs.jmedchem.6b01091
De Petrocellis L, Arroyo FJ, Orlando P, Schiano Moriello A, Vitale RM, Amodeo P, Sánchez A, Roncero C, Bianchini G, Martín MA, López-Alvarado P, Menéndez JC. Correction to Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents. J Med Chem. 2016 Aug 25;59(16):7697. doi: 10.1021/acs.jmedchem.6b01091. Epub 2016 Aug 03. PMID: 27487560.
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Antibacterial Properties of Alkaloid Extracts from Callistemon citrinus and Vernonia adoensis against Staphylococcus aureus and Pseudomonas aeruginosa.

International journal of medicinal chemistry

Mabhiza D, Chitemerere T, Mukanganyama S.
PMID: 26904285
Int J Med Chem. 2016;2016:6304163. doi: 10.1155/2016/6304163. Epub 2016 Jan 20.

The development of new antibiotics from new chemical entities is becoming more and more expensive, time-consuming, and compounded by emerging strains that are drug resistant. Alkaloids are plant secondary metabolites which have been shown to have potent pharmacological activities....

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Mabhiza D, Chitemerere T, Mukanganyama S. Antibacterial Properties of Alkaloid Extracts from Callistemon citrinus and Vernonia adoensis against Staphylococcus aureus and Pseudomonas aeruginosa. Int J Med Chem. 2016;2016:6304163doi: 10.1155/2016/6304163.
Mabhiza, D., Chitemerere, T., & Mukanganyama, S. (2016). Antibacterial Properties of Alkaloid Extracts from Callistemon citrinus and Vernonia adoensis against Staphylococcus aureus and Pseudomonas aeruginosa. International journal of medicinal chemistry, 20166304163. https://doi.org/10.1155/2016/6304163
Mabhiza, Donald, et al. "Antibacterial Properties of Alkaloid Extracts from Callistemon citrinus and Vernonia adoensis against Staphylococcus aureus and Pseudomonas aeruginosa." International journal of medicinal chemistry vol. 2016 (2016): 6304163. doi: https://doi.org/10.1155/2016/6304163
Mabhiza D, Chitemerere T, Mukanganyama S. Antibacterial Properties of Alkaloid Extracts from Callistemon citrinus and Vernonia adoensis against Staphylococcus aureus and Pseudomonas aeruginosa. Int J Med Chem. 2016;2016:6304163. doi: 10.1155/2016/6304163. Epub 2016 Jan 20. PMID: 26904285; PMCID: PMC4745602.
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Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells.

International journal of medicinal chemistry

Lakshmi S, Padmaja G, Remani P.
PMID: 27429805
Int J Med Chem. 2011;2011:253962. doi: 10.1155/2011/253962. Epub 2011 Feb 15.

Curcuma zedoaria belonging to the family Zingiberaceae has been used in the traditional system of medicine in India and Southwest Asia in treating many human ailments and is found to possess many biological activities. The rationale of the present...

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Lakshmi S, Padmaja G, Remani P. Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. Int J Med Chem. 2011;2011:253962doi: 10.1155/2011/253962.
Lakshmi, S., Padmaja, G., & Remani, P. (2011). Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. International journal of medicinal chemistry, 2011253962. https://doi.org/10.1155/2011/253962
Lakshmi, S, et al. "Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells." International journal of medicinal chemistry vol. 2011 (2011): 253962. doi: https://doi.org/10.1155/2011/253962
Lakshmi S, Padmaja G, Remani P. Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. Int J Med Chem. 2011;2011:253962. doi: 10.1155/2011/253962. Epub 2011 Feb 15. PMID: 27429805; PMCID: PMC4939266.
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Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity.

Journal of medicinal chemistry

Bruncko M, Wang L, Sheppard GS, Phillips DC, Tahir SK, Xue J, Erickson S, Fidanze S, Fry E, Hasvold L, Jenkins GJ, Jin S, Judge RA, Kovar PJ, Madar D, Nimmer P, Park C, Petros AM, Rosenberg SH, Smith ML, Song X, Sun C, Tao ZF, Wang X, Xiao Y, Zhang H, Tse C, Leverson JD, Elmore SW, Souers AJ.
PMID: 25933255
J Med Chem. 2015 May 14;58(9):4089. doi: 10.1021/acs.jmedchem.5b00616. Epub 2015 May 01.

No abstract available.

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Bruncko M, Wang L, Sheppard GS, et al. Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity. J Med Chem. 2015;58(9):4089doi: 10.1021/acs.jmedchem.5b00616.
Bruncko, M., Wang, L., Sheppard, G. S., Phillips, D. C., Tahir, S. K., Xue, J., Erickson, S., Fidanze, S., Fry, E., Hasvold, L., Jenkins, G. J., Jin, S., Judge, R. A., Kovar, P. J., Madar, D., Nimmer, P., Park, C., Petros, A. M., Rosenberg, S. H., Smith, M. L., Song, X., Sun, C., Tao, Z. F., Wang, X., Xiao, Y., Zhang, H., Tse, C., Leverson, J. D., Elmore, S. W., & Souers, A. J. (2015). Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity. Journal of medicinal chemistry, 58(9), 4089. https://doi.org/10.1021/acs.jmedchem.5b00616
Bruncko, Milan, et al. "Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity." Journal of medicinal chemistry vol. 58,9 (2015): 4089. doi: https://doi.org/10.1021/acs.jmedchem.5b00616
Bruncko M, Wang L, Sheppard GS, Phillips DC, Tahir SK, Xue J, Erickson S, Fidanze S, Fry E, Hasvold L, Jenkins GJ, Jin S, Judge RA, Kovar PJ, Madar D, Nimmer P, Park C, Petros AM, Rosenberg SH, Smith ML, Song X, Sun C, Tao ZF, Wang X, Xiao Y, Zhang H, Tse C, Leverson JD, Elmore SW, Souers AJ. Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity. J Med Chem. 2015 May 14;58(9):4089. doi: 10.1021/acs.jmedchem.5b00616. Epub 2015 May 01. PMID: 25933255.
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The Fate of Sulfamethazine in Sodium-Hypochlorite-Treated Drinking Water: Monitoring by LC-MS (n) -IT-TOF.

International journal of medicinal chemistry

Melton TC, Brown SD.
PMID: 25954529
Int J Med Chem. 2012;2012:693903. doi: 10.1155/2012/693903. Epub 2012 May 15.

Pharmaceutical compounds represent a rapidly emerging class of environmental contaminants. Such compounds were recently classified by the U.S. Geological Survey, including several antibiotics. An LC-MS/MS screening method for the top five antibiotics in drinking water was developed and validated...

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Melton TC, Brown SD. The Fate of Sulfamethazine in Sodium-Hypochlorite-Treated Drinking Water: Monitoring by LC-MS (n) -IT-TOF. Int J Med Chem. 2012;2012:693903doi: 10.1155/2012/693903.
Melton, T. C., & Brown, S. D. (2012). The Fate of Sulfamethazine in Sodium-Hypochlorite-Treated Drinking Water: Monitoring by LC-MS (n) -IT-TOF. International journal of medicinal chemistry, 2012693903. https://doi.org/10.1155/2012/693903
Melton, Tyler C, and Brown, Stacy D. "The Fate of Sulfamethazine in Sodium-Hypochlorite-Treated Drinking Water: Monitoring by LC-MS (n) -IT-TOF." International journal of medicinal chemistry vol. 2012 (2012): 693903. doi: https://doi.org/10.1155/2012/693903
Melton TC, Brown SD. The Fate of Sulfamethazine in Sodium-Hypochlorite-Treated Drinking Water: Monitoring by LC-MS (n) -IT-TOF. Int J Med Chem. 2012;2012:693903. doi: 10.1155/2012/693903. Epub 2012 May 15. PMID: 25954529; PMCID: PMC4411894.
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Mannich bases: an important pharmacophore in present scenario.

International journal of medicinal chemistry

Bala S, Sharma N, Kajal A, Kamboj S, Saini V.
PMID: 25478226
Int J Med Chem. 2014;2014:191072. doi: 10.1155/2014/191072. Epub 2014 Nov 12.

Mannich bases are the end products of Mannich reaction and are known as beta-amino ketone carrying compounds. Mannich reaction is a carbon-carbon bond forming nucleophilic addition reaction and is a key step in synthesis of a wide variety of...

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Bala S, Sharma N, Kajal A, et al. Mannich bases: an important pharmacophore in present scenario. Int J Med Chem. 2014;2014:191072doi: 10.1155/2014/191072.
Bala, S., Sharma, N., Kajal, A., Kamboj, S., & Saini, V. (2014). Mannich bases: an important pharmacophore in present scenario. International journal of medicinal chemistry, 2014191072. https://doi.org/10.1155/2014/191072
Bala, Suman, et al. "Mannich bases: an important pharmacophore in present scenario." International journal of medicinal chemistry vol. 2014 (2014): 191072. doi: https://doi.org/10.1155/2014/191072
Bala S, Sharma N, Kajal A, Kamboj S, Saini V. Mannich bases: an important pharmacophore in present scenario. Int J Med Chem. 2014;2014:191072. doi: 10.1155/2014/191072. Epub 2014 Nov 12. PMID: 25478226; PMCID: PMC4244926.
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Synthetic Antimicrobial Peptides Exhibit Two Different Binding Mechanisms to the Lipopolysaccharides Isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae.

International journal of medicinal chemistry

Chai H, Allen WE, Hicks RP.
PMID: 25610647
Int J Med Chem. 2014;2014:809283. doi: 10.1155/2014/809283. Epub 2014 Dec 28.

Circular dichroism and (1)H NMR were used to investigate the interactions of a series of synthetic antimicrobial peptides (AMPs) with lipopolysaccharides (LPS) isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae. Previous CD studies with AMPs containing only three Tic-Oic dipeptide...

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Chai H, Allen WE, Hicks RP. Synthetic Antimicrobial Peptides Exhibit Two Different Binding Mechanisms to the Lipopolysaccharides Isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae. Int J Med Chem. 2014;2014:809283doi: 10.1155/2014/809283.
Chai, H., Allen, W. E., & Hicks, R. P. (2014). Synthetic Antimicrobial Peptides Exhibit Two Different Binding Mechanisms to the Lipopolysaccharides Isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae. International journal of medicinal chemistry, 2014809283. https://doi.org/10.1155/2014/809283
Chai, Hanbo, et al. "Synthetic Antimicrobial Peptides Exhibit Two Different Binding Mechanisms to the Lipopolysaccharides Isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae." International journal of medicinal chemistry vol. 2014 (2014): 809283. doi: https://doi.org/10.1155/2014/809283
Chai H, Allen WE, Hicks RP. Synthetic Antimicrobial Peptides Exhibit Two Different Binding Mechanisms to the Lipopolysaccharides Isolated from Pseudomonas aeruginosa and Klebsiella pneumoniae. Int J Med Chem. 2014;2014:809283. doi: 10.1155/2014/809283. Epub 2014 Dec 28. PMID: 25610647; PMCID: PMC4295349.
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Design and synthesis of novel antileishmanial compounds.

International journal of medicinal chemistry

Loedige M.
PMID: 25685554
Int J Med Chem. 2015;2015:302723. doi: 10.1155/2015/302723. Epub 2015 Jan 21.

According to the WHO, infectious diseases, and in particular neglected tropical diseases in poor developing countries, still play a significant role in a vast number of deaths reported worldwide. Among them, leishmaniasis occurs as a complex and clinically diverse...

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Loedige M. Design and synthesis of novel antileishmanial compounds. Int J Med Chem. 2015;2015:302723doi: 10.1155/2015/302723.
Loedige, M. (2015). Design and synthesis of novel antileishmanial compounds. International journal of medicinal chemistry, 2015302723. https://doi.org/10.1155/2015/302723
Loedige, Melanie. "Design and synthesis of novel antileishmanial compounds." International journal of medicinal chemistry vol. 2015 (2015): 302723. doi: https://doi.org/10.1155/2015/302723
Loedige M. Design and synthesis of novel antileishmanial compounds. Int J Med Chem. 2015;2015:302723. doi: 10.1155/2015/302723. Epub 2015 Jan 21. PMID: 25685554; PMCID: PMC4320803.
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Synthesis of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine, beta-adrenergic affinity, inotropic, chronotropic and coronary vasodilating activities.

European journal of medicinal chemistry

Iakovou K, Kazanis M, Vavayannis A, Bruni G, Romeo MR, Massarelli P, Teramoto S, Fujiki H, Mori T.
PMID: 10889316
Eur J Med Chem. 1999 Nov 01;34(11):903-917. doi: 10.1016/s0223-5234(99)00109-9.

Aseries of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine were synthesized and evaluated for inotropic, chronotropic and coronary vasodilating activities in the canine heart, affinity to beta(1)-adrenergic receptor in turkey erythrocytes and affinity to the beta(2)-adrenergic receptor in the rat lung. Among...

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Iakovou K, Kazanis M, Vavayannis A, et al. Synthesis of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine, beta-adrenergic affinity, inotropic, chronotropic and coronary vasodilating activities. Eur J Med Chem. 1999;34(11):903-917doi: 10.1016/s0223-5234(99)00109-9.
Iakovou, K., Kazanis, M., Vavayannis, A., Bruni, G., Romeo, M. R., Massarelli, P., Teramoto, S., Fujiki, H., & Mori, T. (1999). Synthesis of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine, beta-adrenergic affinity, inotropic, chronotropic and coronary vasodilating activities. European journal of medicinal chemistry, 34(11), 903-917. https://doi.org/10.1016/s0223-5234(99)00109-9
Iakovou, et al. "Synthesis of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine, beta-adrenergic affinity, inotropic, chronotropic and coronary vasodilating activities." European journal of medicinal chemistry vol. 34,11 (1999): 903-917. doi: https://doi.org/10.1016/s0223-5234(99)00109-9
Iakovou K, Kazanis M, Vavayannis A, Bruni G, Romeo MR, Massarelli P, Teramoto S, Fujiki H, Mori T. Synthesis of oxypropanolamine derivatives of 3,4-dihydro-2H-1,4-benzoxazine, beta-adrenergic affinity, inotropic, chronotropic and coronary vasodilating activities. Eur J Med Chem. 1999 Nov 01;34(11):903-917. doi: 10.1016/s0223-5234(99)00109-9. PMID: 10889316.
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Showing 13 to 24 of 2012 entries