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Showing 25 to 36 of 860 entries
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Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse.

Journal of toxicologic pathology

Kimura-Kojima H, Unuma K, Funakoshi T, Kato C, Komatsu A, Aki T, Uemura K.
PMID: 27182119
J Toxicol Pathol. 2016 Apr;29(2):131-8. doi: 10.1293/tox.2015-0072. Epub 2016 Jan 17.

The aim of this study was to examine the possible involvement of smooth muscle cell remodeling and the induction of MFG-E8 (milk fat globule protein epidermal growth factor-VIII) in vascular pathophysiology during cocaine administration in cultured cells and rats....

Analysis of autoantibodies to cell cycle-associated antigens.

Modern rheumatology

Fujinaga H, Takeuchi K, Kaneda K, Takasaki Y, Hashimoto H.
PMID: 24383730
Mod Rheumatol. 2001 Sep;11(3):222-9. doi: 10.3109/s101650170008.

Abstract To determine the specificities of autoantibodies targeting cell cycle-associated antigens in rheumatic diseases, we studied 30 sera which were obtained from patients visiting our hospital and which exhibited a variegated speckled pattern in indirect immunofluorescence (IF). The immunoreactivities...

A Malignant Phyllodes Tumor of the Breast in a 6-Year Old Girl.

Breast cancer (Tokyo, Japan)

Sasa M, Morimoto T, Ii K, Tsuzuki H, Kamamura Y, Komaki K, Uyama T, Monden Y.
PMID: 11091535
Breast Cancer. 1995 Apr 30;2(1):71-75. doi: 10.1007/BF02966899.

We recently encountered a 6-year-old girl with a malignant phyllodes tumor of the breast. The patient's mother noticed a tumor on the right breast of her first doughter at 8 months after from her birth. The baby was brought...

New Prognostic Factors Associated with Long-term Survival in Node-Negative Breast Cancer Patients.

Breast cancer (Tokyo, Japan)

Kato T, Kimura T, Takami N, Miyakawa R, Tanaka S, Muraki H, Kamio T, Fujii A, Yamamoto K, Kameoka S, Nishikawa T, Kasajima T.
PMID: 11091746
Breast Cancer. 1999 Oct 25;6(4):370-377. doi: 10.1007/BF02966456.

BACKGROUND: This study was undertaken to determine the absolute and relative value of angiogenesis, proliferating cell nuclear antigen (PCNA) and conventional prognostic factors in predicting relapse-free survival (RFS) and overall survival (OS) rates associated with long-term survival in Japanese...

Multicentric Breast Carcinoma: Evaluation of Clinicopathological and Immunohistochemical Characteristics.

Breast cancer (Tokyo, Japan)

Arihiro K, Kaneko M, Suehiro SI, Yamamoto A, Kurihara K, Takeda S, Kuroi K, Toge T, Inai K.
PMID: 11091756
Breast Cancer. 1996 Dec 20;3(3):181-198. doi: 10.1007/BF02966983.

Multicentric breast carcinomas not diagnosed clinically, were examined by serial step-cut sectioning of the whole breast, and multicentric carcinoma cases were compared with single carcinoma cases with regard to histological and clinicopathological findings. In 7(3.7%) out of 187 surgically...

Active cis-elements of PCNA Promoter in HeLa, HepG2, L-02 and MCF-7 Cell Lines.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Wang L, Li M, Yan PJ, Lu CD.
PMID: 12058190
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2000;32(5):451-458.

Proliferating cell nuclear antigen (PCNA) is an auxiliary factor of DNA polymerase delta and epsilon and functions in DNA replication and repair. Using PCR methods, 17 sites within the human PCNA promoter from 60 to 538 were subjected to...

Immunohistochemical study of PCNA (proliferating cell nuclear antigen) in normal and abnormal endometrium.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Ito K, Sasano H, Watanabe K, Ozawa N, Sato S, Yajima A.
PMID: 11578332
Int J Gynecol Cancer. 1993 Mar;3(2):122-127. doi: 10.1046/j.1525-1438.1993.03020122.x.

To investigate the cell kinetics of human endometrial disorders immunolocation of PCNA (proliferating cell nuclear antigen) was performed in 69 specimens of normal, hyperplastic, or malignant endometrial tissue that had been fixed in formalin and embedded in paraffin. Immunoreactivity...

ErbB-2, a c-erbB-2-coded protein, is expressed in metastatic cells of adenocarcinoma of endometrium, cervix and ovaries.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Sakamoto H, Deng X, Ohtani K, Takami T, Takami M, Shirakawa T, Satoh K.
PMID: 11578513
Int J Gynecol Cancer. 1995 Nov;5(6):411-415. doi: 10.1046/j.1525-1438.1995.05060411.x.

Ten cases of gynecologic malignancies, including three endometrial, two ovarian and four cervical carcinomas, were studied for the expression of a 185 kDa protein (ErbB-2), coded by a proto-oncogene, c-erbB-2, in primary lesions as well as in metastatic lesions....

Chemoprevention of tea on colorectal cancer induced by dimethylhydrazine in Wistar rats.

World journal of gastroenterology

Jia XD, Han C.
PMID: 11819677
World J Gastroenterol. 2000 Oct;6(5):699-703. doi: 10.3748/wjg.v6.i5.699.

AIM:To investigate the chemopreventive effects of green tea and tea pigment on 1,2-dimethylhydrazine (DMH)-induced rat colorectal carcinogenesis.METHODS:Male weaning Wistar rats were randomly allocated into four groups.Rats in the positive control group were given a(c)s.c. injection of DMH, once a...

Suppression of pea nuclear topoisomerase I enzyme activity by pea PCNA.

The Plant journal : for cell and molecular biology

Van Hop D, Gaikwad A, Yadav BS, Reddy MK, Sopory S, Mukherjee SK.
PMID: 10476062
Plant J. 1999 Jul;19(2):153-162. doi: 10.1046/j.1365-313x.1999.00510.x.

Proliferating cell nuclear antigen (PCNA), a highly conserved DNA polymerase accessory protein of eukary- otic kingdom, has not been studied thoroughly in bio- chemical terms in plants. We describe the isolation of the cDNA encoding PCNA from the pea...

[Correlative analysis with proliferating cell nuclear antigen,bromodeoxyuridine,and microscopic observation on golden hamster carcinogenesis model].

Shanghai kou qiang yi xue = Shanghai journal of stomatology

Zhou ZT, Zhang SL, Xu WN, Zhou YM.
PMID: 15159963
Shanghai Kou Qiang Yi Xue. 1997 Mar;6(1):29-31.

The early diagnosis of carcinomatous conversion has special significance on increasing effectiveness.Proliferating cell nuclear antigen(PCNA),bromodeoxyuridine(BRDU)(immunohistochemistry ways),and microscopic diagnosis were applied and observed on golden hamster cheek pouch carcinogenisis model induced by dimethybenzanthracene(DMBA) in order to seek simple,effective,leading and reliable...

Role of hepatitis C virus proteins (C, NS3, NS5A) in hepatic oncogenesis.

Hepatology research : the official journal of the Japan Society of Hepatology

Kasprzak A, Adamek A.
PMID: 17894800
Hepatol Res. 2008 Jan;38(1):1-26. doi: 10.1111/j.1872-034X.2007.00261.x. Epub 2007 Sep 25.

In recent years, the effects of hepatitis C virus (HCV) proteins on hepatocarcinogenesis have undergone intense investigations. The potentially oncogenic proteins include at least three HCV proteins: core (C) protein, NS3, and NS5A. Several authors indicated relationships between subcellular...

Showing 25 to 36 of 860 entries