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Showing 13 to 24 of 28 entries
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Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication.

Frontiers in microbiology

Lefebvre FA, Lécuyer E.
PMID: 28360889
Front Microbiol. 2017 Mar 16;8:377. doi: 10.3389/fmicb.2017.00377. eCollection 2017.

In the evolutionary arms race, symbionts have evolved means to modulate each other's physiology, oftentimes through the dissemination of biological signals. Beyond small molecules and proteins, recent evidence shows that small RNA molecules are transferred between organisms and transmit...

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Lefebvre FA, Lécuyer E. Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication. Front Microbiol. 2017;8:377doi: 10.3389/fmicb.2017.00377.
Lefebvre, F. A., & Lécuyer, E. (2017). Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication. Frontiers in microbiology, 8377. https://doi.org/10.3389/fmicb.2017.00377
Lefebvre, Fabio A, and Lécuyer, Eric. "Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication." Frontiers in microbiology vol. 8 (2017): 377. doi: https://doi.org/10.3389/fmicb.2017.00377
Lefebvre FA, Lécuyer E. Small Luggage for a Long Journey: Transfer of Vesicle-Enclosed Small RNA in Interspecies Communication. Front Microbiol. 2017 Mar 16;8:377. doi: 10.3389/fmicb.2017.00377. eCollection 2017. PMID: 28360889; PMCID: PMC5352665.
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Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles.

Molecular therapy. Methods & clinical development

Prel A, Caval V, Gayon R, Ravassard P, Duthoit C, Payen E, Maouche-Chretien L, Creneguy A, Nguyen TH, Martin N, Piver E, Sevrain R, Lamouroux L, Leboulch P, Deschaseaux F, Bouillé P, Sensébé L, Pagès JC.
PMID: 26528487
Mol Ther Methods Clin Dev. 2015 Oct 21;2:15039. doi: 10.1038/mtm.2015.39. eCollection 2015.

RNA delivery is an attractive strategy to achieve transient gene expression in research projects and in cell- or gene-based therapies. Despite significant efforts investigating vector-directed RNA transfer, there is still a requirement for better efficiency of delivery to primary...

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Prel A, Caval V, Gayon R, et al. Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles. Mol Ther Methods Clin Dev. 2015;2:15039doi: 10.1038/mtm.2015.39.
Prel, A., Caval, V., Gayon, R., Ravassard, P., Duthoit, C., Payen, E., Maouche-Chretien, L., Creneguy, A., Nguyen, T. H., Martin, N., Piver, E., Sevrain, R., Lamouroux, L., Leboulch, P., Deschaseaux, F., Bouillé, P., Sensébé, L., & Pagès, J. C. (2015). Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles. Molecular therapy. Methods & clinical development, 215039. https://doi.org/10.1038/mtm.2015.39
Prel, Anne, et al. "Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles." Molecular therapy. Methods & clinical development vol. 2 (2015): 15039. doi: https://doi.org/10.1038/mtm.2015.39
Prel A, Caval V, Gayon R, Ravassard P, Duthoit C, Payen E, Maouche-Chretien L, Creneguy A, Nguyen TH, Martin N, Piver E, Sevrain R, Lamouroux L, Leboulch P, Deschaseaux F, Bouillé P, Sensébé L, Pagès JC. Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles. Mol Ther Methods Clin Dev. 2015 Oct 21;2:15039. doi: 10.1038/mtm.2015.39. eCollection 2015. PMID: 26528487; PMCID: PMC4613645.
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Illuminating RNA trafficking and functional delivery by extracellular vesicles.

Advanced drug delivery reviews

de Voogt WS, Tanenbaum ME, Vader P.
PMID: 33894328
Adv Drug Deliv Rev. 2021 Jul;174:250-264. doi: 10.1016/j.addr.2021.04.017. Epub 2021 Apr 21.

RNA-based therapeutics are highly promising for the treatment of numerous diseases, by their ability to tackle the genetic origin in multiple possible ways. RNA molecules are, however, incapable of crossing cell membranes, hence a safe and efficient delivery vehicle...

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de Voogt WS, Tanenbaum ME, Vader P. Illuminating RNA trafficking and functional delivery by extracellular vesicles. Adv Drug Deliv Rev. 2021;174:250-264doi: 10.1016/j.addr.2021.04.017.
de Voogt, W. S., Tanenbaum, M. E., & Vader, P. (2021). Illuminating RNA trafficking and functional delivery by extracellular vesicles. Advanced drug delivery reviews, 174250-264. https://doi.org/10.1016/j.addr.2021.04.017
de Voogt, Willemijn S, et al. "Illuminating RNA trafficking and functional delivery by extracellular vesicles." Advanced drug delivery reviews vol. 174 (2021): 250-264. doi: https://doi.org/10.1016/j.addr.2021.04.017
de Voogt WS, Tanenbaum ME, Vader P. Illuminating RNA trafficking and functional delivery by extracellular vesicles. Adv Drug Deliv Rev. 2021 Jul;174:250-264. doi: 10.1016/j.addr.2021.04.017. Epub 2021 Apr 21. PMID: 33894328.
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A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma.

Journal of translational medicine

Geiger C, Regn S, Weinzierl A, Noessner E, Schendel DJ.
PMID: 16045799
J Transl Med. 2005 Jul 26;3:29. doi: 10.1186/1479-5876-3-29.

We present a generic dendritic cell (DC) vaccine strategy for patients with renal cell carcinoma (RCC) based on the use of RNA as a source of multiplex tumor-associated antigens (TAAs). Instead of preparing RNA from tumor tissue of each...

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Geiger C, Regn S, Weinzierl A, et al. A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma. J Transl Med. 2005;3:29doi: 10.1186/1479-5876-3-29.
Geiger, C., Regn, S., Weinzierl, A., Noessner, E., & Schendel, D. J. (2005). A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma. Journal of translational medicine, 329. https://doi.org/10.1186/1479-5876-3-29
Geiger, Christiane, et al. "A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma." Journal of translational medicine vol. 3 (2005): 29. doi: https://doi.org/10.1186/1479-5876-3-29
Geiger C, Regn S, Weinzierl A, Noessner E, Schendel DJ. A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma. J Transl Med. 2005 Jul 26;3:29. doi: 10.1186/1479-5876-3-29. PMID: 16045799; PMCID: PMC1188079.
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The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer.

Cell

Pastuzyn ED, Day CE, Kearns RB, Kyrke-Smith M, Taibi AV, McCormick J, Yoder N, Belnap DM, Erlendsson S, Morado DR, Briggs JAG, Feschotte C, Shepherd JD.
PMID: 29570995
Cell. 2018 Mar 22;173(1):275. doi: 10.1016/j.cell.2018.03.024.

No abstract available.

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Pastuzyn ED, Day CE, Kearns RB, et al. The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell. 2018;173(1):275doi: 10.1016/j.cell.2018.03.024.
Pastuzyn, E. D., Day, C. E., Kearns, R. B., Kyrke-Smith, M., Taibi, A. V., McCormick, J., Yoder, N., Belnap, D. M., Erlendsson, S., Morado, D. R., Briggs, J. A. G., Feschotte, C., & Shepherd, J. D. (2018). The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell, 173(1), 275. https://doi.org/10.1016/j.cell.2018.03.024
Pastuzyn, Elissa D, et al. "The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer." Cell vol. 173,1 (2018): 275. doi: https://doi.org/10.1016/j.cell.2018.03.024
Pastuzyn ED, Day CE, Kearns RB, Kyrke-Smith M, Taibi AV, McCormick J, Yoder N, Belnap DM, Erlendsson S, Morado DR, Briggs JAG, Feschotte C, Shepherd JD. The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell. 2018 Mar 22;173(1):275. doi: 10.1016/j.cell.2018.03.024. PMID: 29570995; PMCID: PMC5923900.
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Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency.

Molecular therapy. Methods & clinical development

Vamva E, Lever AML, Vink CA, Kenyon JC.
PMID: 33145367
Mol Ther Methods Clin Dev. 2020 Sep 21;19:307-319. doi: 10.1016/j.omtm.2020.09.010. eCollection 2020 Dec 11.

Third-generation HIV-1-derived lentiviral vectors are successfully used as therapeutic agents in various clinical applications. To further promote their use, we attempted to enhance vector infectivity by targeting the dimerization and packaging properties of the RNA transfer vector based on...

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Vamva E, Lever AML, Vink CA, et al. Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency. Mol Ther Methods Clin Dev. 2020;19:307-319doi: 10.1016/j.omtm.2020.09.010.
Vamva, E., Lever, A. M. L., Vink, C. A., & Kenyon, J. C. (2020). Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency. Molecular therapy. Methods & clinical development, 19307-319. https://doi.org/10.1016/j.omtm.2020.09.010
Vamva, Eirini, et al. "Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency." Molecular therapy. Methods & clinical development vol. 19 (2020): 307-319. doi: https://doi.org/10.1016/j.omtm.2020.09.010
Vamva E, Lever AML, Vink CA, Kenyon JC. Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency. Mol Ther Methods Clin Dev. 2020 Sep 21;19:307-319. doi: 10.1016/j.omtm.2020.09.010. eCollection 2020 Dec 11. PMID: 33145367; PMCID: PMC7581820.
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Extracellular vesicles from plasma have higher tumour RNA fraction than platelets.

Journal of extracellular vesicles

Brinkman K, Meyer L, Bickel A, Enderle D, Berking C, Skog J, Noerholm M.
PMID: 32341768
J Extracell Vesicles. 2020 Mar 25;9(1):1741176. doi: 10.1080/20013078.2020.1741176. eCollection 2020.

In addition to Circulating Tumour Cells (CTCs), cell-free DNA (cfDNA) and Extracellular Vesicles (EVs), the notion of "Tumour-Educated Platelets" (TEP) has recently emerged as a potential source of tumour-derived biomarkers accessible through blood liquid biopsies. Here we sought to...

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Brinkman K, Meyer L, Bickel A, et al. Extracellular vesicles from plasma have higher tumour RNA fraction than platelets. J Extracell Vesicles. 2020;9(1):1741176doi: 10.1080/20013078.2020.1741176.
Brinkman, K., Meyer, L., Bickel, A., Enderle, D., Berking, C., Skog, J., & Noerholm, M. (2020). Extracellular vesicles from plasma have higher tumour RNA fraction than platelets. Journal of extracellular vesicles, 9(1), 1741176. https://doi.org/10.1080/20013078.2020.1741176
Brinkman, Kay, et al. "Extracellular vesicles from plasma have higher tumour RNA fraction than platelets." Journal of extracellular vesicles vol. 9,1 (2020): 1741176. doi: https://doi.org/10.1080/20013078.2020.1741176
Brinkman K, Meyer L, Bickel A, Enderle D, Berking C, Skog J, Noerholm M. Extracellular vesicles from plasma have higher tumour RNA fraction than platelets. J Extracell Vesicles. 2020 Mar 25;9(1):1741176. doi: 10.1080/20013078.2020.1741176. eCollection 2020. PMID: 32341768; PMCID: PMC7170366.
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[Research Advance of the Roles of N6-methyladenosine in the Regulation of Hematopoiesis--Review].

Zhongguo shi yan xue ye xue za zhi

Wang NN, Li YP, Cheng T, Cheng H.
PMID: 34893144
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2021 Dec;29(6):1972-1976. doi: 10.19746/j.cnki.issn.1009-2137.2021.06.049.

There are more than 150 types of chemical modifications in RNA, mainly methylation, which are widely distributed in all kinds of RNA, including messenger RNA, transfer RNA, ribosomal RNA, non-coding small RNA and long non-coding RNA. In recent years,...

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Wang NN, Li YP, Cheng T, et al. [Research Advance of the Roles of N6-methyladenosine in the Regulation of Hematopoiesis--Review]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2021;29(6):1972-1976doi: 10.19746/j.cnki.issn.1009-2137.2021.06.049.
Wang, N. N., Li, Y. P., Cheng, T., & Cheng, H. (2021). [Research Advance of the Roles of N6-methyladenosine in the Regulation of Hematopoiesis--Review]. Zhongguo shi yan xue ye xue za zhi, 29(6), 1972-1976. https://doi.org/10.19746/j.cnki.issn.1009-2137.2021.06.049
Wang, Ni-Ni, et al. "[Research Advance of the Roles of N6-methyladenosine in the Regulation of Hematopoiesis--Review]." Zhongguo shi yan xue ye xue za zhi vol. 29,6 (2021): 1972-1976. doi: https://doi.org/10.19746/j.cnki.issn.1009-2137.2021.06.049
Wang NN, Li YP, Cheng T, Cheng H. [Research Advance of the Roles of N6-methyladenosine in the Regulation of Hematopoiesis--Review]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2021 Dec;29(6):1972-1976. doi: 10.19746/j.cnki.issn.1009-2137.2021.06.049. Chinese. PMID: 34893144.
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Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth.

FEBS open bio

Ota Y, Takahashi K, Otake S, Tamaki Y, Okada M, Yan I, Aso K, Fujii S, Patel T, Haneda M.
PMID: 34510808
FEBS Open Bio. 2021 Dec;11(12):3276-3292. doi: 10.1002/2211-5463.13294. Epub 2021 Sep 22.

Extracellular vesicles (EV) within the cellular secretome are emerging as modulators of pathological processes involved in tumor growth through their ability to transfer donor-derived RNA into recipient cells. While the effects of tumor and stromal cell EVs within the...

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Ota Y, Takahashi K, Otake S, et al. Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth. FEBS Open Bio. 2021;11(12):3276-3292doi: 10.1002/2211-5463.13294.
Ota, Y., Takahashi, K., Otake, S., Tamaki, Y., Okada, M., Yan, I., Aso, K., Fujii, S., Patel, T., & Haneda, M. (2021). Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth. FEBS open bio, 11(12), 3276-3292. https://doi.org/10.1002/2211-5463.13294
Ota, Yu, et al. "Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth." FEBS open bio vol. 11,12 (2021): 3276-3292. doi: https://doi.org/10.1002/2211-5463.13294
Ota Y, Takahashi K, Otake S, Tamaki Y, Okada M, Yan I, Aso K, Fujii S, Patel T, Haneda M. Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth. FEBS Open Bio. 2021 Dec;11(12):3276-3292. doi: 10.1002/2211-5463.13294. Epub 2021 Sep 22. PMID: 34510808; PMCID: PMC8634862.
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Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment.

Oncoimmunology

Ridder K, Sevko A, Heide J, Dams M, Rupp AK, Macas J, Starmann J, Tjwa M, Plate KH, Sültmann H, Altevogt P, Umansky V, Momma S.
PMID: 26155418
Oncoimmunology. 2015 Mar 19;4(6):e1008371. doi: 10.1080/2162402X.2015.1008371. eCollection 2015 Jun.

Extracellular vesicles (EVs) have been shown to transfer various molecules, including functional RNA between cells and this process has been suggested to be particularly relevant in tumor-host interactions. However, data on EV-mediated RNA transfer has been obtained primarily by

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Ridder K, Sevko A, Heide J, et al. Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment. Oncoimmunology. 2015;4(6):e1008371doi: 10.1080/2162402X.2015.1008371.
Ridder, K., Sevko, A., Heide, J., Dams, M., Rupp, A. K., Macas, J., Starmann, J., Tjwa, M., Plate, K. H., Sültmann, H., Altevogt, P., Umansky, V., & Momma, S. (2015). Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment. Oncoimmunology, 4(6), e1008371. https://doi.org/10.1080/2162402X.2015.1008371
Ridder, Kirsten, et al. "Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment." Oncoimmunology vol. 4,6 (2015): e1008371. doi: https://doi.org/10.1080/2162402X.2015.1008371
Ridder K, Sevko A, Heide J, Dams M, Rupp AK, Macas J, Starmann J, Tjwa M, Plate KH, Sültmann H, Altevogt P, Umansky V, Momma S. Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment. Oncoimmunology. 2015 Mar 19;4(6):e1008371. doi: 10.1080/2162402X.2015.1008371. eCollection 2015 Jun. PMID: 26155418; PMCID: PMC4485784.
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Nucleotide sequence of ATPase subunit 6 gene of maize mitochondria.

Plant physiology

Dewey RE, Levings CS, Timothy DH.
PMID: 16664516
Plant Physiol. 1985 Nov;79(3):914-9. doi: 10.1104/pp.79.3.914.

The ATPase subunit 6, located in the inner mitochondrial membrane, is encoded by mitochondrial genomes in animals and fungi. We have isolated and characterized a mitochondrial gene, designated atp 6, that encodes the subunit 6 polypeptide of Zea mays....

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Dewey RE, Levings CS, Timothy DH. Nucleotide sequence of ATPase subunit 6 gene of maize mitochondria. Plant Physiol. 1985;79(3):914-9doi: 10.1104/pp.79.3.914.
Dewey, R. E., Levings, C. S., & Timothy, D. H. (1985). Nucleotide sequence of ATPase subunit 6 gene of maize mitochondria. Plant physiology, 79(3), 914-9. https://doi.org/10.1104/pp.79.3.914
Dewey, R E, et al. "Nucleotide sequence of ATPase subunit 6 gene of maize mitochondria." Plant physiology vol. 79,3 (1985): 914-9. doi: https://doi.org/10.1104/pp.79.3.914
Dewey RE, Levings CS, Timothy DH. Nucleotide sequence of ATPase subunit 6 gene of maize mitochondria. Plant Physiol. 1985 Nov;79(3):914-9. doi: 10.1104/pp.79.3.914. PMID: 16664516; PMCID: PMC1074995.
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Plant arginyltransferases (ATEs).

Genetics and molecular biology

Domitrovic T, Fausto AK, Silva TF, Romanel E, Vaslin MFS.
PMID: 28199445
Genet Mol Biol. 2017;40(1):253-260. doi: 10.1590/1678-4685-GMB-2016-0084. Epub 2017 Feb 13.

Regulation of protein stability and/or degradation of misfolded and damaged proteins are essential cellular processes. A part of this regulation is mediated by the so-called N-end rule proteolytic pathway, which, in concert with the ubiquitin proteasome system (UPS), drives...

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Domitrovic T, Fausto AK, Silva TF, et al. Plant arginyltransferases (ATEs). Genet Mol Biol. 2017;40(1):253-260doi: 10.1590/1678-4685-GMB-2016-0084.
Domitrovic, T., Fausto, A. K., Silva, T. F., Romanel, E., & Vaslin, M. F. S. (2017). Plant arginyltransferases (ATEs). Genetics and molecular biology, 40(1), 253-260. https://doi.org/10.1590/1678-4685-GMB-2016-0084
Domitrovic, Tatiana, et al. "Plant arginyltransferases (ATEs)." Genetics and molecular biology vol. 40,1 (2017): 253-260. doi: https://doi.org/10.1590/1678-4685-GMB-2016-0084
Domitrovic T, Fausto AK, Silva TF, Romanel E, Vaslin MFS. Plant arginyltransferases (ATEs). Genet Mol Biol. 2017;40(1):253-260. doi: 10.1590/1678-4685-GMB-2016-0084. Epub 2017 Feb 13. PMID: 28199445; PMCID: PMC5452128.
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Showing 13 to 24 of 28 entries