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Bacteroidetocins Target the Essential Outer Membrane Protein BamA of .

mBio

Matano LM, Coyne MJ, García-Bayona L, Comstock LE.
PMID: 34517753
mBio. 2021 Oct 26;12(5):e0228521. doi: 10.1128/mBio.02285-21. Epub 2021 Sep 14.

Bacteroidetocins are a family of antibacterial peptide toxins that are produced by and target members of the phylum

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Matano LM, Coyne MJ, García-Bayona L, et al. Bacteroidetocins Target the Essential Outer Membrane Protein BamA of . mBio. 2021;12(5):e0228521doi: 10.1128/mBio.02285-21.
Matano, L. M., Coyne, M. J., García-Bayona, L., & Comstock, L. E. (2021). Bacteroidetocins Target the Essential Outer Membrane Protein BamA of . mBio, 12(5), e0228521. https://doi.org/10.1128/mBio.02285-21
Matano, Leigh M, et al. "Bacteroidetocins Target the Essential Outer Membrane Protein BamA of ." mBio vol. 12,5 (2021): e0228521. doi: https://doi.org/10.1128/mBio.02285-21
Matano LM, Coyne MJ, García-Bayona L, Comstock LE. Bacteroidetocins Target the Essential Outer Membrane Protein BamA of . mBio. 2021 Oct 26;12(5):e0228521. doi: 10.1128/mBio.02285-21. Epub 2021 Sep 14. PMID: 34517753; PMCID: PMC8546649.
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The Role of Autophagy-Related Proteins in Candida albicans Infections.

Pathogens (Basel, Switzerland)

Tam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM.
PMID: 27043636
Pathogens. 2016 Mar 29;5(2). doi: 10.3390/pathogens5020034.

Autophagy plays an important role in maintaining cell homeostasis by providing nutrients during periods of starvation and removing damaged organelles from the cytoplasm. A marker in the autophagic process is the reversible conjugation of LC3, a membrane scaffolding protein,...

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Tam JM, Mansour MK, Acharya M, et al. The Role of Autophagy-Related Proteins in Candida albicans Infections. Pathogens. 2016;5(2)doi: 10.3390/pathogens5020034.
Tam, J. M., Mansour, M. K., Acharya, M., Sokolovska, A., Timmons, A. K., Lacy-Hulbert, A., & Vyas, J. M. (2016). The Role of Autophagy-Related Proteins in Candida albicans Infections. Pathogens (Basel, Switzerland), 5(2), . https://doi.org/10.3390/pathogens5020034
Tam, Jenny M, et al. "The Role of Autophagy-Related Proteins in Candida albicans Infections." Pathogens (Basel, Switzerland) vol. 5,2 (2016). doi: https://doi.org/10.3390/pathogens5020034
Tam JM, Mansour MK, Acharya M, Sokolovska A, Timmons AK, Lacy-Hulbert A, Vyas JM. The Role of Autophagy-Related Proteins in Candida albicans Infections. Pathogens. 2016 Mar 29;5(2). doi: 10.3390/pathogens5020034. PMID: 27043636; PMCID: PMC4931385.
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Draft Genome Sequence of Pseudomonas aeruginosa Strain BWH047, a Sequence Type 235 Multidrug-Resistant Clinical Isolate Expressing High Levels of Colistin Resistance.

Microbiology resource announcements

Bachta KER, Ozer EA, Pandit A, Marty FM, Mekalanos JJ, Hauser AR.
PMID: 31320415
Microbiol Resour Announc. 2019 Jul 18;8(29). doi: 10.1128/MRA.00623-19.

The Gram-negative bacterium

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Bachta KER, Ozer EA, Pandit A, et al. Draft Genome Sequence of Pseudomonas aeruginosa Strain BWH047, a Sequence Type 235 Multidrug-Resistant Clinical Isolate Expressing High Levels of Colistin Resistance. Microbiol Resour Announc. 2019;8(29)doi: 10.1128/MRA.00623-19.
Bachta, K. E. R., Ozer, E. A., Pandit, A., Marty, F. M., Mekalanos, J. J., & Hauser, A. R. (2019). Draft Genome Sequence of Pseudomonas aeruginosa Strain BWH047, a Sequence Type 235 Multidrug-Resistant Clinical Isolate Expressing High Levels of Colistin Resistance. Microbiology resource announcements, 8(29), . https://doi.org/10.1128/MRA.00623-19
Bachta, Kelly E R, et al. "Draft Genome Sequence of Pseudomonas aeruginosa Strain BWH047, a Sequence Type 235 Multidrug-Resistant Clinical Isolate Expressing High Levels of Colistin Resistance." Microbiology resource announcements vol. 8,29 (2019). doi: https://doi.org/10.1128/MRA.00623-19
Bachta KER, Ozer EA, Pandit A, Marty FM, Mekalanos JJ, Hauser AR. Draft Genome Sequence of Pseudomonas aeruginosa Strain BWH047, a Sequence Type 235 Multidrug-Resistant Clinical Isolate Expressing High Levels of Colistin Resistance. Microbiol Resour Announc. 2019 Jul 18;8(29). doi: 10.1128/MRA.00623-19. PMID: 31320415; PMCID: PMC6639617.
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Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials.

medRxiv : the preprint server for health sciences

Zulauf KE, Green AB, Nguyen AN, Jagdish T, Reif D, Seeley R, Dale A, Kirby JE.
PMID: 32511577
medRxiv. 2020 Apr 25; doi: 10.1101/2020.04.22.20076117.

The SARS-CoV-2 pandemic has caused a severe, international shortage of N95 respirators, which are essential to protect healthcare providers from infection. Given the contemporary limitations of the supply chain, it is imperative to identify effective means of decontaminating, reusing,...

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Zulauf KE, Green AB, Nguyen AN, et al. Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials. medRxiv. 2020;doi: 10.1101/2020.04.22.20076117.
Zulauf, K. E., Green, A. B., Nguyen, A. N., Jagdish, T., Reif, D., Seeley, R., Dale, A., & Kirby, J. E. (2020). Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2020.04.22.20076117
Zulauf, Katelyn E, et al. "Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials." medRxiv : the preprint server for health sciences vol. (2020). doi: https://doi.org/10.1101/2020.04.22.20076117
Zulauf KE, Green AB, Nguyen AN, Jagdish T, Reif D, Seeley R, Dale A, Kirby JE. Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials. medRxiv. 2020 Apr 25; doi: 10.1101/2020.04.22.20076117. PMID: 32511577; PMCID: PMC7276004.
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Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread.

Cell reports

Duncan-Lowey JK, Wiscovitch AL, Wood TE, Goldberg MB, Russo BC.
PMID: 33238111
Cell Rep. 2020 Nov 24;33(8):108409. doi: 10.1016/j.celrep.2020.108409.

During infection, some bacterial pathogens invade the eukaryotic cytosol and spread between cells of an epithelial monolayer. Intercellular spread occurs when these pathogens push against the plasma membrane, forming protrusions that are engulfed by adjacent cells. Here, we show...

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Duncan-Lowey JK, Wiscovitch AL, Wood TE, et al. Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread. Cell Rep. 2020;33(8):108409doi: 10.1016/j.celrep.2020.108409.
Duncan-Lowey, J. K., Wiscovitch, A. L., Wood, T. E., Goldberg, M. B., & Russo, B. C. (2020). Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread. Cell reports, 33(8), 108409. https://doi.org/10.1016/j.celrep.2020.108409
Duncan-Lowey, Jeffrey K, et al. "Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread." Cell reports vol. 33,8 (2020): 108409. doi: https://doi.org/10.1016/j.celrep.2020.108409
Duncan-Lowey JK, Wiscovitch AL, Wood TE, Goldberg MB, Russo BC. Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread. Cell Rep. 2020 Nov 24;33(8):108409. doi: 10.1016/j.celrep.2020.108409. PMID: 33238111; PMCID: PMC7792532.
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Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis.

Open forum infectious diseases

Piantadosi A, Mukerji SS, Chitneni P, Cho TA, Cosimi LA, Hung DT, Goldberg MB, Sabeti PC, Kuritzkes DR, Grad YH.
PMID: 28761901
Open Forum Infect Dis. 2017 Jul 28;4(3):ofx138. doi: 10.1093/ofid/ofx138. eCollection 2017.

Enteroviruses cause a wide spectrum of clinical disease. In this study, we describe the case of a young man with orchitis and aseptic meningitis who was diagnosed with enterovirus infection. Using unbiased "metagenomic" massively parallel sequencing, we assembled a...

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Piantadosi A, Mukerji SS, Chitneni P, et al. Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis. Open Forum Infect Dis. 2017;4(3):ofx138doi: 10.1093/ofid/ofx138.
Piantadosi, A., Mukerji, S. S., Chitneni, P., Cho, T. A., Cosimi, L. A., Hung, D. T., Goldberg, M. B., Sabeti, P. C., Kuritzkes, D. R., & Grad, Y. H. (2017). Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis. Open forum infectious diseases, 4(3), ofx138. https://doi.org/10.1093/ofid/ofx138
Piantadosi, Anne, et al. "Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis." Open forum infectious diseases vol. 4,3 (2017): ofx138. doi: https://doi.org/10.1093/ofid/ofx138
Piantadosi A, Mukerji SS, Chitneni P, Cho TA, Cosimi LA, Hung DT, Goldberg MB, Sabeti PC, Kuritzkes DR, Grad YH. Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis. Open Forum Infect Dis. 2017 Jul 28;4(3):ofx138. doi: 10.1093/ofid/ofx138. eCollection 2017. PMID: 28761901; PMCID: PMC5534216.
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Caging targets for destruction.

Cell host & microbe

Stamm LM, Heller DM, Goldberg MB.
PMID: 21075349
Cell Host Microbe. 2010 Nov 18;8(5):391-3. doi: 10.1016/j.chom.2010.10.010.

Intracellular bacterial pathogens engage in a tug-of-war with innate host defenses. In this issue of Cell Host & Microbe, Mostowy et al. (2010) identify a role for the septin family of cytoskeletal proteins in targeting intracellular Shigella to the...

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Stamm LM, Heller DM, Goldberg MB. Caging targets for destruction. Cell Host Microbe. 2010;8(5):391-3doi: 10.1016/j.chom.2010.10.010.
Stamm, L. M., Heller, D. M., & Goldberg, M. B. (2010). Caging targets for destruction. Cell host & microbe, 8(5), 391-3. https://doi.org/10.1016/j.chom.2010.10.010
Stamm, Luisa M, et al. "Caging targets for destruction." Cell host & microbe vol. 8,5 (2010): 391-3. doi: https://doi.org/10.1016/j.chom.2010.10.010
Stamm LM, Heller DM, Goldberg MB. Caging targets for destruction. Cell Host Microbe. 2010 Nov 18;8(5):391-3. doi: 10.1016/j.chom.2010.10.010. PMID: 21075349.
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Epidemiologic Investigation of a Cluster of Neuroinvasive Bacillus cereus Infections in 5 Patients With Acute Myelogenous Leukemia.

Open forum infectious diseases

Rhee C, Klompas M, Tamburini FB, Fremin BJ, Chea N, Epstein L, Halpin AL, Guh A, Gallen R, Coulliette A, Gee J, Hsieh C, Desjardins CA, Pedamullu CS, DeAngelo DJ, Manzo VE, Folkerth RD, Milner DA, Pecora N, Osborne M, Chalifoux-Judge D, Bhatt AS, Yokoe DS.
PMID: 26269794
Open Forum Infect Dis. 2015 Jul 01;2(3):ofv096. doi: 10.1093/ofid/ofv096. eCollection 2015 Sep.

Background.  Five neuroinvasive Bacillus cereus infections (4 fatal) occurred in hospitalized patients with acute myelogenous leukemia (AML) during a 9-month period, prompting an investigation by infection control and public health officials. Methods.  Medical records of case-patients were reviewed and...

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Rhee C, Klompas M, Tamburini FB, et al. Epidemiologic Investigation of a Cluster of Neuroinvasive Bacillus cereus Infections in 5 Patients With Acute Myelogenous Leukemia. Open Forum Infect Dis. 2015;2(3):ofv096doi: 10.1093/ofid/ofv096.
Rhee, C., Klompas, M., Tamburini, F. B., Fremin, B. J., Chea, N., Epstein, L., Halpin, A. L., Guh, A., Gallen, R., Coulliette, A., Gee, J., Hsieh, C., Desjardins, C. A., Pedamullu, C. S., DeAngelo, D. J., Manzo, V. E., Folkerth, R. D., Milner, D. A., Pecora, N., Osborne, M., Chalifoux-Judge, D., Bhatt, A. S., & Yokoe, D. S. (2015). Epidemiologic Investigation of a Cluster of Neuroinvasive Bacillus cereus Infections in 5 Patients With Acute Myelogenous Leukemia. Open forum infectious diseases, 2(3), ofv096. https://doi.org/10.1093/ofid/ofv096
Rhee, Chanu, et al. "Epidemiologic Investigation of a Cluster of Neuroinvasive Bacillus cereus Infections in 5 Patients With Acute Myelogenous Leukemia." Open forum infectious diseases vol. 2,3 (2015): ofv096. doi: https://doi.org/10.1093/ofid/ofv096
Rhee C, Klompas M, Tamburini FB, Fremin BJ, Chea N, Epstein L, Halpin AL, Guh A, Gallen R, Coulliette A, Gee J, Hsieh C, Desjardins CA, Pedamullu CS, DeAngelo DJ, Manzo VE, Folkerth RD, Milner DA, Pecora N, Osborne M, Chalifoux-Judge D, Bhatt AS, Yokoe DS. Epidemiologic Investigation of a Cluster of Neuroinvasive Bacillus cereus Infections in 5 Patients With Acute Myelogenous Leukemia. Open Forum Infect Dis. 2015 Jul 01;2(3):ofv096. doi: 10.1093/ofid/ofv096. eCollection 2015 Sep. PMID: 26269794; PMCID: PMC4531223.
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A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion.

iScience

Park JS, Helble JD, Lazarus JE, Yang G, Blondel CJ, Doench JG, Starnbach MN, Waldor MK.
PMID: 30590252
iScience. 2019 Jan 25;11:71-84. doi: 10.1016/j.isci.2018.12.011. Epub 2018 Dec 14.

The invasion of Chlamydia trachomatis, an obligate intracellular bacterium, into epithelial cells is driven by a complex interplay of host and bacterial factors. To comprehensively define the host genes required for pathogen invasion, we undertook a fluorescence-activated cell sorting...

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Park JS, Helble JD, Lazarus JE, et al. A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion. iScience. 2018;11:71-84doi: 10.1016/j.isci.2018.12.011.
Park, J. S., Helble, J. D., Lazarus, J. E., Yang, G., Blondel, C. J., Doench, J. G., Starnbach, M. N., & Waldor, M. K. (2019). A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion. iScience, 1171-84. https://doi.org/10.1016/j.isci.2018.12.011
Park, Joseph S, et al. "A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion." iScience vol. 11 (2019): 71-84. doi: https://doi.org/10.1016/j.isci.2018.12.011
Park JS, Helble JD, Lazarus JE, Yang G, Blondel CJ, Doench JG, Starnbach MN, Waldor MK. A FACS-Based Genome-wide CRISPR Screen Reveals a Requirement for COPI in Chlamydia trachomatis Invasion. iScience. 2019 Jan 25;11:71-84. doi: 10.1016/j.isci.2018.12.011. Epub 2018 Dec 14. PMID: 30590252; PMCID: PMC6308251.
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Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads.

medRxiv : the preprint server for health sciences

Callahan C, Lee R, Lee G, Zulauf KE, Kirby JE, Arnaout R.
PMID: 32587981
medRxiv. 2020 Jun 14; doi: 10.1101/2020.06.12.20128736.

The urgent need for large-scale diagnostic testing for SARS-CoV-2 has prompted pursuit of sample-collection methods of sufficient sensitivity to replace sampling of the nasopharynx (NP). Among these alternatives is collection of nasal-swab samples, which can be performed by the...

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Callahan C, Lee R, Lee G, et al. Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads. medRxiv. 2020;doi: 10.1101/2020.06.12.20128736.
Callahan, C., Lee, R., Lee, G., Zulauf, K. E., Kirby, J. E., & Arnaout, R. (2020). Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2020.06.12.20128736
Callahan, Cody, et al. "Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads." medRxiv : the preprint server for health sciences vol. (2020). doi: https://doi.org/10.1101/2020.06.12.20128736
Callahan C, Lee R, Lee G, Zulauf KE, Kirby JE, Arnaout R. Nasal-Swab Testing Misses Patients with Low SARS-CoV-2 Viral Loads. medRxiv. 2020 Jun 14; doi: 10.1101/2020.06.12.20128736. PMID: 32587981; PMCID: PMC7310639.
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Distinguishing gene flow between malaria parasite populations.

PLoS genetics

Brown TS, Arogbokun O, Buckee CO, Chang HH.
PMID: 34928954
PLoS Genet. 2021 Dec 20;17(12):e1009335. doi: 10.1371/journal.pgen.1009335. eCollection 2021 Dec.

Measuring gene flow between malaria parasite populations in different geographic locations can provide strategic information for malaria control interventions. Multiple important questions pertaining to the design of such studies remain unanswered, limiting efforts to operationalize genomic surveillance tools for...

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Brown TS, Arogbokun O, Buckee CO, et al. Distinguishing gene flow between malaria parasite populations. PLoS Genet. 2021;17(12):e1009335doi: 10.1371/journal.pgen.1009335.
Brown, T. S., Arogbokun, O., Buckee, C. O., & Chang, H. H. (2021). Distinguishing gene flow between malaria parasite populations. PLoS genetics, 17(12), e1009335. https://doi.org/10.1371/journal.pgen.1009335
Brown, Tyler S, et al. "Distinguishing gene flow between malaria parasite populations." PLoS genetics vol. 17,12 (2021): e1009335. doi: https://doi.org/10.1371/journal.pgen.1009335
Brown TS, Arogbokun O, Buckee CO, Chang HH. Distinguishing gene flow between malaria parasite populations. PLoS Genet. 2021 Dec 20;17(12):e1009335. doi: 10.1371/journal.pgen.1009335. eCollection 2021 Dec. PMID: 34928954; PMCID: PMC8726502.
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Efficient flow synthesis of human antimicrobial peptides.

Australian journal of chemistry

Albin JS, Pentelute BL.
PMID: 32431323
Aust J Chem. 2020 Apr;73(4):380-388. doi: 10.1071/CH20043. Epub 2020 Apr 08.

Organisms from all kingdoms of life have evolved a vast array of peptidic natural products to defend against microbes. These are known collectively as antimicrobial peptides (AMPs) or host defense peptides, reflecting their abilities to not only directly kill...

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Albin JS, Pentelute BL. Efficient flow synthesis of human antimicrobial peptides. Aust J Chem. 2020;73(4):380-388doi: 10.1071/CH20043.
Albin, J. S., & Pentelute, B. L. (2020). Efficient flow synthesis of human antimicrobial peptides. Australian journal of chemistry, 73(4), 380-388. https://doi.org/10.1071/CH20043
Albin, John S, and Pentelute, Bradley L. "Efficient flow synthesis of human antimicrobial peptides." Australian journal of chemistry vol. 73,4 (2020): 380-388. doi: https://doi.org/10.1071/CH20043
Albin JS, Pentelute BL. Efficient flow synthesis of human antimicrobial peptides. Aust J Chem. 2020 Apr;73(4):380-388. doi: 10.1071/CH20043. Epub 2020 Apr 08. PMID: 32431323; PMCID: PMC7236790.
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Showing 13 to 24 of 34 entries