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Showing 1297 to 1307 of 1307 entries
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Apixaban in low-weight patients with cancer-associated thrombosis: A cross sectional study of drug levels.

Research and practice in thrombosis and haemostasis

Bravo Villa V, Romero J, Rojas-Zaldivar E, Cervantes M, Villa-Márquez MDR, Baz P, Cesarman-Maus G.
PMID: 33870027
Res Pract Thromb Haemost. 2021 Mar 23;5(3):421-425. doi: 10.1002/rth2.12492. eCollection 2021 Mar.

INTRODUCTION: Apixaban, a direct factor Xa inhibitor, has been shown to be at least as safe and probably more effective than dalteparin for the treatment of cancer-associated thrombosis (CAT) as reported in the ADAM-VTE and Caravaggio studies, which included...

Patient selection for hemophilia gene therapy: Real-life data from a single center.

Research and practice in thrombosis and haemostasis

Krumb E, Lambert C, Hermans C.
PMID: 33870024
Res Pract Thromb Haemost. 2021 Mar 14;5(3):390-394. doi: 10.1002/rth2.12494. eCollection 2021 Mar.

BACKGROUND: While the number of individuals with hemophilia who are expected to be or have already been included in gene therapy trials has been regularly reported, the number of unscreened or excluded individuals, in addition to the reasons for...

Exploring the utility of a novel point-of-care whole blood thrombin generation assay following trauma: A pilot study.

Research and practice in thrombosis and haemostasis

Ferrara MJ, MacArthur TA, Butenas S, Mann KG, Immermann JM, Spears GM, Bailey KR, Kozar RA, Heller SF, Loomis EA, Stephens D, Park MS.
PMID: 33870025
Res Pract Thromb Haemost. 2021 Mar 08;5(3):395-402. doi: 10.1002/rth2.12483. eCollection 2021 Mar.

INTRODUCTION: Plasma thrombin generation kinetics as measured by the calibrated automated thrombogram (CAT) assay is a predictor of symptomatic venous thromboembolism after trauma. We hypothesized that data from a new prototype assay for measurement of thrombin generation kinetics in...

Updating the Canadian Hemophilia Outcomes-Kids' Life Assessment Tool (CHO-KLAT) in the era of extended half-life clotting factor concentrates.

Research and practice in thrombosis and haemostasis

Price VE, Dover S, Blanchette VS, Klaassen RJ, Belletrutti M, Bruce AAK, Chan AK, Wakefield C, Carcao M, Bouskill V, Young NL.
PMID: 33870026
Res Pract Thromb Haemost. 2021 Mar 27;5(3):403-411. doi: 10.1002/rth2.12498. eCollection 2021 Mar.

INTRODUCTION: The purpose of this study was to review and update the content of the Canadian Hemophilia Outcomes-Kids' Life Assessment Tool version 2.0 (CHO-KLAT), in the context of extended half-life (EHL) factor concentrates (FCs) and to establish the validity...

On-Ticagrelor Platelet Reactivity and Clinical Outcome in Patients Undergoing Percutaneous Coronary Intervention for Acute Coronary Syndrome.

Thrombosis and haemostasis

Laine M, Panagides V, Frère C, Cuisset T, Gouarne C, Jouve B, Lemesle G, Paganelli F, Alessi MC, Mancini J, Bonello L.
PMID: 33260230
Thromb Haemost. 2021 Jul;121(7):923-930. doi: 10.1055/a-1326-5110. Epub 2020 Dec 01.

BACKGROUND:  A strong association between on-thienopyridine platelet reactivity (PR) and the risk of both thrombotic and bleeding events in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) has been demonstrated. However, no study has analyzed the relationship...

Coronary Plaque Erosion after Abemaciclib Treatment Onset: An Unknown Side Effect?.

Thrombosis and haemostasis

Vera A, Rivero F, Salamanca J, Alvarado-Casas T, Alfonso F.
PMID: 33260247
Thromb Haemost. 2021 Jul;121(7):976-978. doi: 10.1055/a-1326-7028. Epub 2020 Dec 01.

The current article describes a 72-year-old woman who suffered an acute myocardial infarction due to plaque erosion (PE) 2 weeks after abemaciclib treatment onset due to advanced breast cancer. Abemaciclib is a cyclin-dependent kinase 4 and 6 inhibitor that...

Emicizumab Dosing in Children and Adults with Hemophilia A: Simulating a User-Friendly and Cost-Efficient Regimen.

Thrombosis and haemostasis

Bukkems LH, Fischer K, Kremer-Hovinga I, Donners AAM, Fijnvandraat K, Schutgens REG, Cnossen MH, Mathôt RAA.
PMID: 33946119
Thromb Haemost. 2021 May 04; doi: 10.1055/a-1499-0030. Epub 2021 May 04.

BACKGROUND:  When emicizumab is dosed according to label, clinicians are obligated to discard or overdose medication due to discrepancies between calculated dose and vial content. The aim of this study was to compose a cost-efficient emicizumab maintenance dosing regimen...

Low-dose immune tolerance induction alone or with immunosuppressants according to prognostic risk factors in Chinese children with hemophilia A inhibitors.

Research and practice in thrombosis and haemostasis

Li Z, Chen Z, Liu G, Cheng X, Yao W, Huang K, Li G, Zhen Y, Wu X, Cai S, Poon MC, Wu R.
PMID: 34278191
Res Pract Thromb Haemost. 2021 Jul 14;5(5):e12562. doi: 10.1002/rth2.12562. eCollection 2021 Jul.

BACKGROUND: In developing countries, children with hemophilia A (HA) with high-titer inhibitor and poor immune tolerance induction (ITI) prognostic risk(s) cannot afford the recommended high- or intermediate-dose ITI.OBJECTIVES: To determine the efficacy of low-dose ITI (plasma-derived factor VIII [FVIII]/von...

COVID-19 is Associated with an Acquired Factor XIII Deficiency.

Thrombosis and haemostasis

von Meijenfeldt FA, Havervall S, Adelmeijer J, Lundström A, Magnusson M, Mackman N, Thalin C, Lisman T.
PMID: 33742434
Thromb Haemost. 2021 Dec;121(12):1668-1669. doi: 10.1055/a-1450-8414. Epub 2021 Mar 19.

No abstract available.

Risk factors for gastrointestinal bleeding in patients with gastrointestinal cancer using edoxaban.

Journal of thrombosis and haemostasis : JTH

Bosch FTM, Mulder FI, Huisman MV, Zwicker JI, Di Nisio M, Carrier M, Segers A, Verhamme P, Middeldorp S, Weitz JI, Grosso MA, Duggal A, Büller HR, Wang TF, Garcia D, Kamphuisen PW, Raskob GE, van Es N.
PMID: 34455706
J Thromb Haemost. 2021 Dec;19(12):3008-3017. doi: 10.1111/jth.15516. Epub 2021 Sep 12.

BACKGROUND: In the Hokusai VTE Cancer study, the risk of major bleeding was 2.9% higher in the edoxaban group compared with the dalteparin group, mainly due to more gastrointestinal bleedings in patients with gastrointestinal cancer. The identification of risk...

A mixed-methods study to evaluate a patient-designed tool to reduce harm from cancer-associated thrombosis: The EMPOWER study.

Research and practice in thrombosis and haemostasis

Baddeley E, Torrens-Burton A, Newman A, Nelson A, Pease N, Nelson R, Noble S.
PMID: 34401640
Res Pract Thromb Haemost. 2021 Aug 11;5(5):e12545. doi: 10.1002/rth2.12545. eCollection 2021 Jul.

INTRODUCTION: Venous thromboembolism (VTE) is a common and serious complication of systemic anticancer therapies. Delays in presentation increase risk of death or long-term morbidity.BACKGROUND: A patient charity developed an information video for patients receiving systemic anticancer therapy including what...

Showing 1297 to 1307 of 1307 entries