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Showing 13 to 24 of 3215 entries
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The assessment of proinflammatory cytokines in the patients with the history of cerebral venous sinus thrombosis.

Iranian journal of neurology

Akbari F, Ghorbani A, Fatehi F.
PMID: 27326361
Iran J Neurol. 2016 Apr 03;15(2):75-9.

BACKGROUND: Evidence is accumulating that venous thromboembolism is not limited to coagulation system and immune system seems to be involved in formation and resolution of thrombus. Some studies have demonstrated the role of inflammatory factors in deep venous thrombosis...

Role of high-mobility group box 1 in patients with acute obstructive suppurative cholangitis-induced sepsis.

Journal of inflammation research

Singh A, Feng Y, Mahato N, Li J, Wu C, Gong J.
PMID: 25792849
J Inflamm Res. 2015 Mar 11;8:71-7. doi: 10.2147/JIR.S77539. eCollection 2015.

BACKGROUND: High-mobility group box 1 (HMGB1) is a proinflammatory cytokine that plays an active role during the pathogenesis of inflammatory processes. The primary aim of this study was to detect whether HMGB1 is involved in the pathogenesis of acute...

Autoimmune-like drug-induced liver injury: a review and update for the clinician.

Expert opinion on drug metabolism & toxicology

Stine JG, Northup PG.
PMID: 27402321
Expert Opin Drug Metab Toxicol. 2016 Nov;12(11):1291-1301. doi: 10.1080/17425255.2016.1211110. Epub 2016 Jul 21.

INTRODUCTION: Autoimmune-like drug-induced liver injury (DI-AIH) is a rare but serious event with a growing body of scientific evidence and a fair degree of uncertainty. Areas covered: This review covers the definition, pathophysiology, treatment and patient-centered outcomes of DI-AIH...

The role of tumor necrosis factor-alpha -308 G/A and transforming growth factor-beta 1 -915 G/C polymorphisms in childhood idiopathic thrombocytopenic purpura.

Turkish journal of haematology : official journal of Turkish Society of Haematology

Okulu E, İleri T, Koşan Çulha V, Azık FM, Eğin Y, Uysal Z, Akar N.
PMID: 27264363
Turk J Haematol. 2011 Sep 05;28(3):170-5. doi: 10.5152/tjh.2011.50.

OBJECTIVE: To increase our understanding of the etiology of idiopathic thrombocytopenic purpura (ITP) some cytokine gene polymorphisms were analyzed for susceptibility to the disease. The aim of this study was to investigate the role of tumor necrosis factor-alpha (TNF-α)...

Practical recommendations for the use of therapeutic drug monitoring of biopharmaceuticals in inflammatory diseases.

Clinical pharmacology : advances and applications

Dreesen E, Bossuyt P, Mulleman D, Gils A, Pascual-Salcedo D.
PMID: 29042821
Clin Pharmacol. 2017 Oct 03;9:101-111. doi: 10.2147/CPAA.S138414. eCollection 2017.

Biopharmaceuticals directed against tumor necrosis factor-alpha, integrins, interleukins, interferons and their receptors have become key agents for the management of inflammatory diseases in the fields of gastroenterology, rheumatology, dermatology and neurology. However, response to these treatments is far from...

The Efficacy of Biologic Therapy for the Management of Palmoplantar Psoriasis and Palmoplantar Pustulosis: A Systematic Review.

Dermatology and therapy

Sanchez IM, Sorenson E, Levin E, Liao W.
PMID: 29143230
Dermatol Ther (Heidelb). 2017 Dec;7(4):425-446. doi: 10.1007/s13555-017-0207-0. Epub 2017 Nov 15.

INTRODUCTION: Palmoplantar psoriasis (PP) and palmoplantar pustulosis (PPP) are diseases affecting the hands and/or feet that can cause marked physical discomfort and functional disability. The tumor necrosis factor-alpha antagonists adalimumab, etanercept, and infliximab, the interleukin (IL)-17A inhibitors ixekizumab and...

Guanabenz Prevents d-Galactosamine/Lipopolysaccharide-Induced Liver Damage and Mortality.

Frontiers in immunology

Perego J, Bourbon C, Chasson L, Laprie C, Spinelli L, Camosseto V, Gatti E, Pierre P.
PMID: 28659918
Front Immunol. 2017 Jun 13;8:679. doi: 10.3389/fimmu.2017.00679. eCollection 2017.

Multi-organ failure in response to uncontrolled microbial infection is characterized by low blood pressure accompanied by a systemic over-inflammation state, caused by massive pro-inflammatory cytokines release and liver damage. Recently, the integrated stress response (ISR), characterized by eukaryotic translation...

"Soldier's Heart": A Genetic Basis for Elevated Cardiovascular Disease Risk Associated with Post-traumatic Stress Disorder.

Frontiers in molecular neuroscience

Pollard HB, Shivakumar C, Starr J, Eidelman O, Jacobowitz DM, Dalgard CL, Srivastava M, Wilkerson MD, Stein MB, Ursano RJ.
PMID: 27721742
Front Mol Neurosci. 2016 Sep 23;9:87. doi: 10.3389/fnmol.2016.00087. eCollection 2016.

"Soldier's Heart," is an American Civil War term linking post-traumatic stress disorder (PTSD) with increased propensity for cardiovascular disease (CVD). We have hypothesized that there might be a quantifiable genetic basis for this linkage. To test this hypothesis we...

Effect of compression garments on delayed-onset muscle soreness and blood inflammatory markers after eccentric exercise: a randomized controlled trial.

Journal of exercise rehabilitation

Kim J, Kim J, Lee J.
PMID: 29114528
J Exerc Rehabil. 2017 Oct 30;13(5):541-545. doi: 10.12965/jer.1735088.554. eCollection 2017 Oct.

The purpose of this study was to investigate how compression garments, applied after eccentric exercise, can affect delayed onset muscle soreness (DOMS) and inflammatory markers. Sixteen healthy male university students enrolled in this study and were randomly assigned to...

A Case of Granuloma Annulare Associated with Secukinumab Use.

Case reports in dermatological medicine

Bonomo L, Ghoneim S, Levitt J.
PMID: 28611928
Case Rep Dermatol Med. 2017;2017:5918708. doi: 10.1155/2017/5918708. Epub 2017 May 22.

Granuloma annulare (GA) is a benign inflammatory dermatosis characterized clinically by dermal papules and annular plaques. The pathogenesis of GA is not well understood, although it is thought to result from a delayed-type hypersensitivity reaction in which inflammatory cells...

Evaluation of plasma leptin, tumor necrosis factor-α, and prealbumin as prognostic biomarkers during clinical recovery from acute exacerbations of chronic obstructive pulmonary disease.

Lung India : official organ of Indian Chest Society

Mohan A, Arora S, Uniyal A, Poulose R, Luthra K, Pandey RM, Guleria R.
PMID: 28144052
Lung India. 2017 Jan-Feb;34(1):3-8. doi: 10.4103/0970-2113.197101.

BACKGROUND: Inflammatory and nutritional biomarkers have an important bearing on outcomes of acute exacerbations of chronic obstructive pulmonary disease (AECOPD), but the temporal profile of these compounds during an acute episode is unclear.PATIENTS AND METHODS: Plasma leptin, prealbumin, and...

Tumor Necrosis Factor Alpha -308 G/A Single Nucleotide Polymorphism and Risk of Sperm Abnormalities in Iranian Males.

International journal of fertility & sterility

Khademi Bami M, Dehghan Tezerjani M, Montazeri F, Ashrafzadeh Mehrjardi HR, Ghasemi-Esmailabad S, Sheikhha MH, Kalantar SM.
PMID: 28670429
Int J Fertil Steril. 2017 Jul-Sep;11(2):112-116. doi: 10.22074/ijfs.2017.4830. Epub 2017 Feb 16.

BACKGROUND: Signaling molecules such as cytokines regulate spermatogenesis during the maturation of germ cells and sperm apoptosis. Tumor necrosis factor alpha (TNFα) is one of the most-documented cytokines that is involved in spermatogenesis. We investigated the association of the...

Showing 13 to 24 of 3215 entries