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Showing 301 to 306 of 306 entries
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DNA Methylation and Intra-Clonal Heterogeneity: The Chronic Myeloid Leukemia Model.

Cancers

Lebecque B, Bourgne C, Vidal V, Berger MG.
PMID: 34298798
Cancers (Basel). 2021 Jul 17;13(14). doi: 10.3390/cancers13143587.

Chronic Myeloid Leukemia (CML) is a model to investigate the impact of tumor intra-clonal heterogeneity in personalized medicine. Indeed, tyrosine kinase inhibitors (TKIs) target the BCR-ABL fusion protein, which is considered the major CML driver. TKI use has highlighted...

Ticagrelor added to methotrexate improves rheumatoid arthritis disease severity.

Rheumatology (Oxford, England)

Garshick MS, Rosenthal PB, Luttrell-Williams E, Cronstein BN, Berger JS.
PMID: 34142122
Rheumatology (Oxford). 2021 Nov 03;60(11):5473-5475. doi: 10.1093/rheumatology/keab481.

No abstract available.

Discovery of a tsunami deposit from the Bronze Age Santorini eruption at Malia (Crete): impact, chronology, extension.

Scientific reports

Lespez L, Lescure S, Saulnier-Copard S, Glais A, Berger JF, Lavigne F, Pearson C, Virmoux C, Müller Celka S, Pomadère M.
PMID: 34326405
Sci Rep. 2021 Jul 29;11(1):15487. doi: 10.1038/s41598-021-94859-1.

A geomorphological survey immediately west of the Minoan town of Malia (Crete) shows that a tsunami resulting from the Bronze Age Santorini eruption reached the outskirts of the Palatial center. Sediment cores testify a unique erosional event during the...

Comparison of Days Alive Out of Hospital With Initial Invasive vs Conservative Management: A Prespecified Analysis of the ISCHEMIA Trial.

JAMA cardiology

White HD, O'Brien SM, Alexander KP, Boden WE, Bangalore S, Li J, Manjunath CN, Lopez-Sendon JL, Peteiro J, Gosselin G, Berger JS, Maggioni AP, Reynolds HR, Hochman JS, Maron DJ.
PMID: 33938917
JAMA Cardiol. 2021 Sep 01;6(9):1023-1031. doi: 10.1001/jamacardio.2021.1651.

IMPORTANCE: Traditional time-to-event analyses rate events occurring early as more important than later events, even if later events are more severe, eg, death. Days alive out of hospital (DAOH) adds a patient-focused perspective beyond trial end points.OBJECTIVE: To compare...

Clinical and Financial Implications of 2 Treatment Strategies for Donor-derived Hepatitis C Infections.

Transplantation direct

Stewart ZA, Stern J, Ali NM, Kalia HS, Khalil K, Jonchhe S, Weldon EP, Dieter RA, Lewis TC, Funches N, Crosby S, Seow M, Berger JC, Dagher NN, Gelb BE, Watkins AC, Moazami N, Smith DE, Kon ZN, Chang SH, Reyentovich A, Angel LF, Montgomery RA, Lonze BE.
PMID: 34514117
Transplant Direct. 2021 Sep 07;7(10):e762. doi: 10.1097/TXD.0000000000001222. eCollection 2021 Oct.

Transplanting hepatitis C viremic donor organs into hepatitis C virus (HCV)-negative recipients is becoming increasingly common; however, practices for posttransplant direct-acting antiviral (DAA) treatment vary widely. Protracted insurance authorization processes for DAA therapy often lead to treatment delays.METHODS: At...

Economic burden of rivaroxaban and warfarin among nonvalvular atrial fibrillation patients with obesity and polypharmacy.

Journal of comparative effectiveness research

Laliberté F, Ashton V, Kharat A, Lejeune D, Moore KT, Jung Y, Lefebvre P, Berger JS.
PMID: 34378989
J Comp Eff Res. 2021 Nov;10(16):1235-1250. doi: 10.2217/cer-2021-0150. Epub 2021 Aug 11.

No abstract available.

Showing 301 to 306 of 306 entries