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Showing 13 to 24 of 771 entries
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The role of CCN family genes in haematological malignancies.

Journal of cell communication and signaling

Wells JE, Howlett M, Cheung LC, Kees UR.
PMID: 26026820
J Cell Commun Signal. 2015 Sep;9(3):267-78. doi: 10.1007/s12079-015-0296-4. Epub 2015 May 31.

Haematological malignancies, although a broad range of specific disease types, continue to show considerable overlap in classification, and patients are treated using similar chemotherapy regimes. In this review we look at the role of the CCN family of matricellular...

Hong Kong consensus recommendations on the management of hepatocellular carcinoma.

Liver cancer

Poon RT, Cheung TT, Kwok PC, Lee AS, Li TW, Loke KL, Chan SL, Cheung MT, Lai TW, Cheung CC, Cheung FY, Loo CK, But YK, Hsu SJ, Yu SC, Yau T.
PMID: 26020029
Liver Cancer. 2015 Mar;4(1):51-69. doi: 10.1159/000367728.

BACKGROUND: Hepatocellular carcinoma (HCC) is particularly prevalent in Hong Kong because of the high prevalence of chronic hepatitis B (CHB) infection; HCC is the fourth commonest cancer in men and the seventh commonest in women, and it is the...

A population-based study of the epidemiology of pancreatic cancer: a brief report.

Current oncology (Toronto, Ont.)

Raju RS, Coburn N, Liu N, Porter JM, Seung SJ, Cheung MC, Goyert N, Leighl NB, Hoch JS, Trudeau ME, Evans WK, Dainty KN, Earle CC, Mittmann N.
PMID: 26715886
Curr Oncol. 2015 Dec;22(6):e478-84. doi: 10.3747/co.22.2653.

OBJECTIVE: Administrative data are used to describe the pancreatic cancer (pcc) population. The analysis examines demographic details, incidence, site, survival, and factors influencing mortality in a cohort of individuals diagnosed with pcc.METHODS: Incident cases of pcc diagnosed in Ontario...

Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4.

ACS medicinal chemistry letters

Cheung M, Bao W, Behm DJ, Brooks CA, Bury MJ, Dowdell SE, Eidam HS, Fox RM, Goodman KB, Holt DA, Lee D, Roethke TJ, Willette RN, Xu X, Ye G, Thorneloe KS.
PMID: 28523109
ACS Med Chem Lett. 2017 Mar 20;8(5):549-554. doi: 10.1021/acsmedchemlett.7b00094. eCollection 2017 May 11.

Transient Receptor Potential Vanilloid 4 (TRPV4) is a member of the Transient Receptor Potential (TRP) superfamily of cation channels. TRPV4 is expressed in the vascular endothelium in the lung and regulates the integrity of the alveolar septal barrier. Increased...

Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells.

Frontiers in pharmacology

Lee JY, Kuo CW, Tsai SL, Cheng SM, Chen SH, Chan HH, Lin CH, Lin KY, Li CF, Kanwar JR, Leung EY, Cheung CC, Huang WJ, Wang YC, Cheung CH.
PMID: 27065869
Front Pharmacol. 2016 Mar 31;7:81. doi: 10.3389/fphar.2016.00081. eCollection 2016.

SAHA is a class I HDAC/HDAC6 co-inhibitor and an autophagy inducer currently undergoing clinical investigations in breast cancer patients. However, the molecular mechanism of action of SAHA in breast cancer cells remains unclear. In this study, we found that...

CORRECTION. Arabidopsis RGLG2, Functioning as a RING E3 Ligase, Interacts with AtERF53 and Negatively Regulates the Plant Drought Stress Response.

Plant physiology

Cheng MC, Hsieh EJ, Chen JH, Chen HY, Lin TP.
PMID: 26826724
Plant Physiol. 2016 Feb;170(2):1162-3. doi: 10.1104/pp.16.00025.

No abstract available.

The use of the isotropic orientation factor in fluorescence resonance energy transfer (FRET) studies of the actin filament.

Journal of fluorescence

Censullo R, Martin JC, Cheung HC.
PMID: 24241625
J Fluoresc. 1992 Sep;2(3):141-55. doi: 10.1007/BF00866929.

A Dale-Eisinger style analysis (R. E. Daleet al., Biophys. J. 26, 161, 1979) is used to produce three-dimensional plots that display the limits on the average orientation factor [Symbol: see text]K (2)[Symbol: see text] that is required to calculate...

Hiatus Hernia Repair with Bilateral Oesophageal Fixation.

Surgery research and practice

Mendis R, Cheung C, Martin D.
PMID: 26065030
Surg Res Pract. 2015;2015:693138. doi: 10.1155/2015/693138. Epub 2015 Apr 30.

Background. Despite advances in surgical repair of hiatus hernias, there remains a high radiological recurrence rate. We performed a novel technique incorporating bilateral oesophageal fixation and evaluated outcomes, principally symptom improvement and hernia recurrence. Methods. A retrospective study was...

Luminescent mononuclear and binuclear cyclometalated palladium(II) complexes of 6-phenyl-2,2 bipyridines: spectroscopic and structural comparisons with platinum(II) analogues.

Inorganic chemistry

Lai SW, Cheung TC, Chan MC, Cheung KK, Peng SM, Che CM.
PMID: 11272533
Inorg Chem. 2000 Jan 24;39(2):255-62. doi: 10.1021/ic991089g.

The mononuclear cyclometalated Pd(II) complexes [Pd(L1)X] (HL1 = 6-phenyl-2,2'-bipyridine; X = Cl, la; Br, 1b; I, 1c), [Pd(L1)PPh3]+ (1d), [Pd(L2-5)Cl] [2a-5a, HL2-5 = 4-(aryl)-6-phenyl-2,2'-bipyridine; aryl = phenyl (2), 4-chlorophenyl (3), 4-tolyl (4), 4-methoxyphenyl (5)] and the binuclear derivatives [Pd2(L1-5)2(mu-dppm)]2+...

The unusual mammographic appearance of breasts augmented by autologous fat injection.

Breast (Edinburgh, Scotland)

Cheung M, Houssami N, Lim E.
PMID: 14731998
Breast. 2000 Aug;9(4):220-2. doi: 10.1054/brst.2000.0168.

We report the case of a woman presenting to our centre with two breast lumps, 12 months after undergoing breast augmentation with autologous fat injection. Mammography showed a very unusual appearance, with most of the breast parenchyma displaced anteriorly...

The Fermi Gamma-Ray Space Telescope discovers the pulsar in the young galactic supernova remnant CTA 1.

Science (New York, N.Y.)

Abdo AA, Ackermann M, Atwood WB, Baldini L, Ballet J, Barbiellini G, Baring MG, Bastieri D, Baughman BM, Bechtol K, Bellazzini R, Berenji B, Blandford RD, Bloom ED, Bogaert G, Bonamente E, Borgland AW, Bregeon J, Brez A, Brigida M, Bruel P, Burnett TH, Caliandro GA, Cameron RA, Caraveo PA, Carlson P, Casandjian JM, Cecchi C, Charles E, Chekhtman A, Cheung CC, Chiang J, Ciprini S, Claus R, Cohen-Tanugi J, Cominsky LR, Conrad J, Cutini S, Davis DS, Dermer CD, de Angelis A, de Palma F, Digel SW, Dormody M, do Couto E Silva E, Drell PS, Dubois R, Dumora D, Edmonds Y, Farnier C, Focke WB, Fukazawa Y, Funk S, Fusco P, Gargano F, Gasparrini D, Gehrels N, Germani S, Giebels B, Giglietto N, Giordano F, Glanzman T, Godfrey G, Grenier IA, Grondin MH, Grove JE, Guillemot L, Guiriec S, Harding AK, Hartman RC, Hays E, Hughes RE, Jóhannesson G, Johnson AS, Johnson RP, Johnson TJ, Johnson WN, Kamae T, Kanai Y, Kanbach G, Katagiri H, Kawai N, Kerr M, Kishishita T, Kiziltan B, Knödlseder J, Kocian ML, Komin N, Kuehn F, Kuss M, Latronico L, Lemoine-Goumard M, Longo F, Lonjou V, Loparco F, Lott B, Lovellette MN, Lubrano P, Makeev A, Marelli M, Mazziotta MN, McEnery JE, McGlynn S, Meurer C, Michelson PF, Mineo T, Mitthumsiri W, Mizuno T, Moiseev AA, Monte C, Monzani ME, Morselli A, Moskalenko IV, Murgia S, Nakamori T, Nolan PL, Nuss E, Ohno M, Ohsugi T, Okumura A, Omodei N, Orlando E, Ormes JF, Ozaki M, Paneque D, Panetta JH, Parent D, Pelassa V, Pepe M, Pesce-Rollins M, Piano G, Pieri L, Piron F, Porter TA, Rainò S, Rando R, Ray PS, Razzano M, Reimer A, Reimer O, Reposeur T, Ritz S, Rochester LS, Rodriguez AY, Romani RW, Roth M, Ryde F, Sadrozinski HF, Sanchez D, Sander A, Parkinson PM, Schalk TL, Sellerholm A, Sgrò C, Siskind EJ, Smith DA, Smith PD, Spandre G, Spinelli P, Starck JL, Strickman MS, Suson DJ, Tajima H, Takahashi H, Takahashi T, Tanaka T, Thayer JB, Thayer JG, Thompson DJ, Thorsett SE, Tibaldo L, Torres DF, Tosti G, Tramacere A, Usher TL, Van Etten A, Vilchez N, Vitale V, Wang P, Watters K, Winer BL, Wood KS, Yasuda H, Ylinen T, Ziegler M.
PMID: 18927355
Science. 2008 Nov 21;322(5905):1218-21. doi: 10.1126/science.1165572. Epub 2008 Oct 16.

Energetic young pulsars and expanding blast waves [supernova remnants (SNRs)] are the most visible remains after massive stars, ending their lives, explode in core-collapse supernovae. The Fermi Gamma-Ray Space Telescope has unveiled a radio quiet pulsar located near the...

Synthesis and structural characterization of mono- and bisfunctional o-carboranes.

Dalton transactions (Cambridge, England : 2003)

Cheung MS, Chan HS, Xie Z.
PMID: 15995745
Dalton Trans. 2005 Jul 21;(14):2375-81. doi: 10.1039/b504076k. Epub 2005 Jun 09.

Functionalized o-carboranes are interesting ligands for transition metals. Reaction of LiC2B10H11 with Me2NCH2CH2Cl in toluene afforded 1-Me2NCH2CH2-1,2-C2B10H11 (1). Treatment of 1 with 1 equiv. of n-BuLi gave [(Me2NCH2CH2)C2B10H10]Li ([1]Li), which was a very useful synthon for the production of...

Showing 13 to 24 of 771 entries