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Showing 181 to 186 of 186 entries
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Admission Urinary and Serum Metabolites Predict Renal Outcomes in Hospitalized Patients With Cirrhosis.

Hepatology (Baltimore, Md.)

Bajaj JS, Garcia-Tsao G, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Subramanian RM, Thuluvath P, Fagan A, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Wong F.
PMID: 34002868
Hepatology. 2021 Nov;74(5):2699-2713. doi: 10.1002/hep.31907. Epub 2021 Jul 08.

BACKGROUND AND AIMS: Acute kidney injury (AKI) has a poor prognosis in cirrhosis. Given the variability of creatinine, the prediction of AKI and dialysis by other markers is needed. The aim of this study is to determine the role...

Network dysfunction in cognitively normal APOE ε4 carriers is related to subclinical tau.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Butt OH, Meeker KL, Wisch JK, Schindler SE, Fagan AM, Benzinger TLS, Cruchaga C, Holtzman DM, Morris JC, Ances BM.
PMID: 34002449
Alzheimers Dement. 2021 May 18; doi: 10.1002/alz.12375. Epub 2021 May 18.

INTRODUCTION: Apolipoprotein E (APOE) ε4 allele status is associated with amyloid and tau-related pathological changes related to Alzheimer's disease (AD). However, it is unknown whether brain network changes are related to amyloid beta (Aβ) and/or tau-related pathology in cognitively...

Stool microbiota are superior to saliva in distinguishing cirrhosis and hepatic encephalopathy using machine learning.

Journal of hepatology

Saboo K, Petrakov NV, Shamsaddini A, Fagan A, Gavis EA, Sikaroodi M, McGeorge S, Gillevet PM, Iyer RK, Bajaj JS.
PMID: 34793867
J Hepatol. 2021 Nov 15; doi: 10.1016/j.jhep.2021.11.011. Epub 2021 Nov 15.

BACKGROUND AND AIMS: Salivary and stool microbiota are altered in cirrhosis. Since stool is logistically difficult to collect compared to saliva, it is important to determine their relative capability in differentiating groups. We aimed to determine the ability of...

Evaluation of the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment Suicide Risk Modeling Clinical Program in the Veterans Health Administration.

JAMA network open

McCarthy JF, Cooper SA, Dent KR, Eagan AE, Matarazzo BB, Hannemann CM, Reger MA, Landes SJ, Trafton JA, Schoenbaum M, Katz IR.
PMID: 34661661
JAMA Netw Open. 2021 Oct 01;4(10):e2129900. doi: 10.1001/jamanetworkopen.2021.29900.

IMPORTANCE: The Veterans Health Administration (VHA) implemented a national clinical program using a suicide risk prediction algorithm, Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment (REACH VET), in which clinicians facilitate care enhancements for individuals identified in local top...

Effect of fat reformulated dairy food consumption on postprandial flow-mediated dilatation and cardiometabolic risk biomarkers compared with conventional dairy: a randomized, controlled trial.

The American journal of clinical nutrition

Markey O, Vasilopoulou D, Kliem KE, Fagan CC, Grandison AS, Sutton R, Humphries DJ, Todd S, Jackson KG, Givens DI, Lovegrove JA.
PMID: 35020795
Am J Clin Nutr. 2022 Jan 10; doi: 10.1093/ajcn/nqab428. Epub 2022 Jan 10.

BACKGROUND: Longer-term consumption of saturated fatty acid (SFA)-reduced, monounsaturated fatty acid (MUFA)-enriched dairy products have been reported to improve fasting flow-mediated vasodilation (FMD). Yet, their impact on endothelial function in the postprandial state warrants investigation.OBJECTIVES: To compare the impact...

The Longitudinal Early-onset Alzheimer's Disease Study (LEADS): Framework and methodology.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Apostolova LG, Aisen P, Eloyan A, Fagan A, Fargo KN, Foroud T, Gatsonis C, Grinberg LT, Jack CR, Kramer J, Koeppe R, Kukull WA, Murray ME, Nudelman K, Rumbaugh M, Toga A, Vemuri P, Trullinger A, Iaccarino L, Day GS, Graff-Radford NR, Honig LS, Jones DT, Masdeu J, Mendez M, Musiek E, Onyike CU, Rogalski E, Salloway S, Wolk DA, Wingo TS, Carrillo MC, Dickerson BC, Rabinovici GD.
PMID: 34018654
Alzheimers Dement. 2021 Dec;17(12):2043-2055. doi: 10.1002/alz.12350. Epub 2021 May 21.

Patients with early-onset Alzheimer's disease (EOAD) are commonly excluded from large-scale observational and therapeutic studies due to their young age, atypical presentation, or absence of pathogenic mutations. The goals of the Longitudinal EOAD Study (LEADS) are to (1) define...

Showing 181 to 186 of 186 entries