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Showing 169 to 173 of 173 entries
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Long-term safety of extended levonorgestrel-containing oral contraceptives in the United States.

Contraception

Kaplan S, Bertoia ML, Wang FT, Zhou L, Lass A, Evans A, Dhanda S, Roy D, Seeger JD.
PMID: 34599911
Contraception. 2022 Jan;105:26-32. doi: 10.1016/j.contraception.2021.09.013. Epub 2021 Sep 30.

OBJECTIVES: To compare the safety profile of Seasonique, a 91-day levonorgestrel-containing combined oral contraceptive (COCSTUDY DESIGN: A new user cohort study was conducted in a US health care database from 2006 to 2017. Each 91-day COCRESULTS: Of the 25,593...

Evaluation of Publication of Pediatric Drug Trials.

JAMA network open

Srivastava A, Bourgeois FT.
PMID: 33852005
JAMA Netw Open. 2021 Apr 01;4(4):e215829. doi: 10.1001/jamanetworkopen.2021.5829.

No abstract available.

Association between Inflammatory Conditions and Alzheimer's Disease Age of Onset in Down Syndrome.

Journal of clinical medicine

Lai F, Mercaldo N, Wang CM, Hersch GG, Rosas HD.
PMID: 34300282
J Clin Med. 2021 Jul 15;10(14). doi: 10.3390/jcm10143116.

Adults with Down syndrome (DS) have an exceptionally high prevalence of Alzheimer disease (AD), with an earlier age of onset compared with the neurotypical population. In addition to beta amyloid, immunological processes involved in neuroinflammation and in peripheral inflammatory/autoimmune...

The automation of relevant trial registration screening for systematic review updates: an evaluation study on a large dataset of ClinicalTrials.gov registrations.

BMC medical research methodology

Surian D, Bourgeois FT, Dunn AG.
PMID: 34922458
BMC Med Res Methodol. 2021 Dec 18;21(1):281. doi: 10.1186/s12874-021-01485-6.

BACKGROUND: Clinical trial registries can be used as sources of clinical evidence for systematic review synthesis and updating. Our aim was to evaluate methods for identifying clinical trial registrations that should be screened for inclusion in updates of published...

Developmental deficits and staging of dynamics of age associated Alzheimer's disease neurodegeneration and neuronal loss in subjects with Down syndrome.

Acta neuropathologica communications

Wegiel J, Flory M, Kuchna I, Nowicki K, Wegiel J, Ma SY, Zhong N, Bobrowicz TW, de Leon M, Lai F, Silverman WP, Wisniewski T.
PMID: 34983655
Acta Neuropathol Commun. 2022 Jan 04;10(1):2. doi: 10.1186/s40478-021-01300-9.

The increased life expectancy of individuals with Down syndrome (DS) is associated with increased prevalence of trisomy 21-linked early-onset Alzheimer's disease (EOAD) and dementia. The aims of this study of 14 brain regions including the entorhinal cortex, hippocampus, basal...

Showing 169 to 173 of 173 entries