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Showing 25 to 36 of 160 entries
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Classification of Cardiomyopathies from MR Cine Images Using Convolutional Neural Network with Transfer Learning.

Diagnostics (Basel, Switzerland)

Germain P, Vardazaryan A, Padoy N, Labani A, Roy C, Schindler TH, El Ghannudi S.
PMID: 34573896
Diagnostics (Basel). 2021 Aug 27;11(9). doi: 10.3390/diagnostics11091554.

The automatic classification of various types of cardiomyopathies is desirable but has never been performed using a convolutional neural network (CNN). The purpose of this study was to evaluate currently available CNN models to classify cine magnetic resonance (cine-MR)...

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Germain P, Vardazaryan A, Padoy N, et al. Classification of Cardiomyopathies from MR Cine Images Using Convolutional Neural Network with Transfer Learning. Diagnostics (Basel). 2021;11(9)doi: 10.3390/diagnostics11091554.
Germain, P., Vardazaryan, A., Padoy, N., Labani, A., Roy, C., Schindler, T. H., & El Ghannudi, S. (2021). Classification of Cardiomyopathies from MR Cine Images Using Convolutional Neural Network with Transfer Learning. Diagnostics (Basel, Switzerland), 11(9), . https://doi.org/10.3390/diagnostics11091554
Germain, Philippe, et al. "Classification of Cardiomyopathies from MR Cine Images Using Convolutional Neural Network with Transfer Learning." Diagnostics (Basel, Switzerland) vol. 11,9 (2021). doi: https://doi.org/10.3390/diagnostics11091554
Germain P, Vardazaryan A, Padoy N, Labani A, Roy C, Schindler TH, El Ghannudi S. Classification of Cardiomyopathies from MR Cine Images Using Convolutional Neural Network with Transfer Learning. Diagnostics (Basel). 2021 Aug 27;11(9). doi: 10.3390/diagnostics11091554. PMID: 34573896; PMCID: PMC8470356.
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Dietary supplements: When too much of a good thing becomes harmful.

Clinical case reports

Mehta N, Germain MS, Quiel L.
PMID: 34552730
Clin Case Rep. 2021 Sep 15;9(9). doi: 10.1002/ccr3.3614. eCollection 2021 Sep.

While dietary supplements are generally "safe," they must be appropriately consumed as they have different regulatory standards than traditional pharmaceutical medications and require oversight to ensure that a good thing does not become harmful.

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Mehta N, Germain MS, Quiel L. Dietary supplements: When too much of a good thing becomes harmful. Clin Case Rep. 2021;9(9)doi: 10.1002/ccr3.3614.
Mehta, N., Germain, M. S., & Quiel, L. (2021). Dietary supplements: When too much of a good thing becomes harmful. Clinical case reports, 9(9), . https://doi.org/10.1002/ccr3.3614
Mehta, Neal, et al. "Dietary supplements: When too much of a good thing becomes harmful." Clinical case reports vol. 9,9 (2021). doi: https://doi.org/10.1002/ccr3.3614
Mehta N, Germain MS, Quiel L. Dietary supplements: When too much of a good thing becomes harmful. Clin Case Rep. 2021 Sep 15;9(9). doi: 10.1002/ccr3.3614. eCollection 2021 Sep. PMID: 34552730; PMCID: PMC8443412.
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DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation.

Proceedings of the National Academy of Sciences of the United States of America

Dong R, Aksel T, Chan W, Germain RN, Vale RD, Douglas SM.
PMID: 34588308
Proc Natl Acad Sci U S A. 2021 Oct 05;118(40). doi: 10.1073/pnas.2109057118.

Receptor clustering plays a key role in triggering cellular activation, but the relationship between the spatial configuration of clusters and the elicitation of downstream intracellular signals remains poorly understood. We developed a DNA-origami-based system that is easily adaptable to...

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Dong R, Aksel T, Chan W, et al. DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation. Proc Natl Acad Sci U S A. 2021;118(40)doi: 10.1073/pnas.2109057118.
Dong, R., Aksel, T., Chan, W., Germain, R. N., Vale, R. D., & Douglas, S. M. (2021). DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation. Proceedings of the National Academy of Sciences of the United States of America, 118(40), . https://doi.org/10.1073/pnas.2109057118
Dong, Rui, et al. "DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation." Proceedings of the National Academy of Sciences of the United States of America vol. 118,40 (2021). doi: https://doi.org/10.1073/pnas.2109057118
Dong R, Aksel T, Chan W, Germain RN, Vale RD, Douglas SM. DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation. Proc Natl Acad Sci U S A. 2021 Oct 05;118(40). doi: 10.1073/pnas.2109057118. PMID: 34588308; PMCID: PMC8501782.
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Case Report: First Two Identified Cases of Fabry Disease in Central Asia.

Frontiers in genetics

Cainelli F, Argandykov D, Kaldarbekov D, Mukarov M, Tran Thi Phuong L, Germain DP.
PMID: 33986771
Front Genet. 2021 Apr 27;12:657824. doi: 10.3389/fgene.2021.657824. eCollection 2021.

No abstract available.

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Cainelli F, Argandykov D, Kaldarbekov D, et al. Case Report: First Two Identified Cases of Fabry Disease in Central Asia. Front Genet. 2021;12:657824doi: 10.3389/fgene.2021.657824.
Cainelli, F., Argandykov, D., Kaldarbekov, D., Mukarov, M., Tran Thi Phuong, L., & Germain, D. P. (2021). Case Report: First Two Identified Cases of Fabry Disease in Central Asia. Frontiers in genetics, 12657824. https://doi.org/10.3389/fgene.2021.657824
Cainelli, Francesca, et al. "Case Report: First Two Identified Cases of Fabry Disease in Central Asia." Frontiers in genetics vol. 12 (2021): 657824. doi: https://doi.org/10.3389/fgene.2021.657824
Cainelli F, Argandykov D, Kaldarbekov D, Mukarov M, Tran Thi Phuong L, Germain DP. Case Report: First Two Identified Cases of Fabry Disease in Central Asia. Front Genet. 2021 Apr 27;12:657824. doi: 10.3389/fgene.2021.657824. eCollection 2021. PMID: 33986771; PMCID: PMC8110900.
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On the open sea propagation of water waves generated by a moving bed.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

Constantin A, Germain P.
PMID: 22393110
Philos Trans A Math Phys Eng Sci. 2012 Apr 13;370(1964):1587-601. doi: 10.1098/rsta.2011.0443.

Within the framework of linear theory, applicable far from the shore, we investigate the two-dimensional propagation of waves generated in the ocean by a sudden seabed deformation.

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Constantin A, Germain P. On the open sea propagation of water waves generated by a moving bed. Philos Trans A Math Phys Eng Sci. 2012;370(1964):1587-601doi: 10.1098/rsta.2011.0443.
Constantin, A., & Germain, P. (2012). On the open sea propagation of water waves generated by a moving bed. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 370(1964), 1587-601. https://doi.org/10.1098/rsta.2011.0443
Constantin, Adrian, and Germain, Pierre. "On the open sea propagation of water waves generated by a moving bed." Philosophical transactions. Series A, Mathematical, physical, and engineering sciences vol. 370,1964 (2012): 1587-601. doi: https://doi.org/10.1098/rsta.2011.0443
Constantin A, Germain P. On the open sea propagation of water waves generated by a moving bed. Philos Trans A Math Phys Eng Sci. 2012 Apr 13;370(1964):1587-601. doi: 10.1098/rsta.2011.0443. PMID: 22393110.
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Isolation of Nuclei in Tagged Cell Types (INTACT), RNA Extraction and Ribosomal RNA Degradation to Prepare Material for RNA-Seq.

Bio-protocol

Reynoso MA, Pauluzzi GC, Cabanlit S, Velasco J, Bazin J, Deal R, Brady S, Sinha N, Bailey-Serres J, Kajala K.
PMID: 34286007
Bio Protoc. 2018 Apr 05;8(7):e2458. doi: 10.21769/BioProtoc.2458. eCollection 2018 Apr 05.

Gene expression is dynamically regulated on many levels, including chromatin accessibility and transcription. In order to study these nuclear regulatory events, we describe our method to purify nuclei with Isolation of Nuclei in TAgged Cell Types (INTACT). As nuclear...

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Reynoso MA, Pauluzzi GC, Cabanlit S, et al. Isolation of Nuclei in Tagged Cell Types (INTACT), RNA Extraction and Ribosomal RNA Degradation to Prepare Material for RNA-Seq. Bio Protoc. 2018;8(7):e2458doi: 10.21769/BioProtoc.2458.
Reynoso, M. A., Pauluzzi, G. C., Cabanlit, S., Velasco, J., Bazin, J., Deal, R., Brady, S., Sinha, N., Bailey-Serres, J., & Kajala, K. (2018). Isolation of Nuclei in Tagged Cell Types (INTACT), RNA Extraction and Ribosomal RNA Degradation to Prepare Material for RNA-Seq. Bio-protocol, 8(7), e2458. https://doi.org/10.21769/BioProtoc.2458
Reynoso, Mauricio A, et al. "Isolation of Nuclei in Tagged Cell Types (INTACT), RNA Extraction and Ribosomal RNA Degradation to Prepare Material for RNA-Seq." Bio-protocol vol. 8,7 (2018): e2458. doi: https://doi.org/10.21769/BioProtoc.2458
Reynoso MA, Pauluzzi GC, Cabanlit S, Velasco J, Bazin J, Deal R, Brady S, Sinha N, Bailey-Serres J, Kajala K. Isolation of Nuclei in Tagged Cell Types (INTACT), RNA Extraction and Ribosomal RNA Degradation to Prepare Material for RNA-Seq. Bio Protoc. 2018 Apr 05;8(7):e2458. doi: 10.21769/BioProtoc.2458. eCollection 2018 Apr 05. PMID: 34286007; PMCID: PMC8275268.
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Ligands and DNA in the allosteric control of retinoid receptors function.

Essays in biochemistry

Germain P, Rochel N, Bourguet W.
PMID: 34296739
Essays Biochem. 2021 Dec 17;65(6):887-899. doi: 10.1042/EBC20200168.

Retinoids are a family of compounds that include both vitamin A (all-trans retinol) and its naturally occurring metabolites such as retinoic acids (e.g. all-trans retinoic acid) as well as synthetic analogs. They are critically involved in the regulation of...

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Germain P, Rochel N, Bourguet W. Ligands and DNA in the allosteric control of retinoid receptors function. Essays Biochem. 2021;65(6):887-899doi: 10.1042/EBC20200168.
Germain, P., Rochel, N., & Bourguet, W. (2021). Ligands and DNA in the allosteric control of retinoid receptors function. Essays in biochemistry, 65(6), 887-899. https://doi.org/10.1042/EBC20200168
Germain, Pierre, et al. "Ligands and DNA in the allosteric control of retinoid receptors function." Essays in biochemistry vol. 65,6 (2021): 887-899. doi: https://doi.org/10.1042/EBC20200168
Germain P, Rochel N, Bourguet W. Ligands and DNA in the allosteric control of retinoid receptors function. Essays Biochem. 2021 Dec 17;65(6):887-899. doi: 10.1042/EBC20200168. PMID: 34296739.
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A dataset from a 3-year network of field measurements of soil organic nitrogen mineralization under a mild oceanic temperate climate.

Data in brief

Morvan T, Lambert Y, Germain P, Beff L.
PMID: 33553536
Data Brief. 2021 Jan 26;35:106795. doi: 10.1016/j.dib.2021.106795. eCollection 2021 Apr.

Improved assessment and prediction of soil organic nitrogen (SON) mineralization is essential, as it contributes significantly to the nitrogen (N) nutrition of crops and remains a major economic and environmental challenge. SON mineralization is a function of soil properties,...

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Morvan T, Lambert Y, Germain P, et al. A dataset from a 3-year network of field measurements of soil organic nitrogen mineralization under a mild oceanic temperate climate. Data Brief. 2021;35:106795doi: 10.1016/j.dib.2021.106795.
Morvan, T., Lambert, Y., Germain, P., & Beff, L. (2021). A dataset from a 3-year network of field measurements of soil organic nitrogen mineralization under a mild oceanic temperate climate. Data in brief, 35106795. https://doi.org/10.1016/j.dib.2021.106795
Morvan, Thierry, et al. "A dataset from a 3-year network of field measurements of soil organic nitrogen mineralization under a mild oceanic temperate climate." Data in brief vol. 35 (2021): 106795. doi: https://doi.org/10.1016/j.dib.2021.106795
Morvan T, Lambert Y, Germain P, Beff L. A dataset from a 3-year network of field measurements of soil organic nitrogen mineralization under a mild oceanic temperate climate. Data Brief. 2021 Jan 26;35:106795. doi: 10.1016/j.dib.2021.106795. eCollection 2021 Apr. PMID: 33553536; PMCID: PMC7859313.
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Lentivirus-mediated Conditional Gene Expression.

Bio-protocol

Rommereim L, Akhade AS, Germain RN, Fraser IDC, Subramanian N.
PMID: 34859120
Bio Protoc. 2021 Nov 05;11(21):e4205. doi: 10.21769/BioProtoc.4205. eCollection 2021 Nov 05.

The ability to identify the role of a particular gene within a system is dependent on control of the expression of that gene. In this protocol, we describe a method for stable, conditional expression of Nod-Like receptors (NLRs) in...

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Rommereim L, Akhade AS, Germain RN, et al. Lentivirus-mediated Conditional Gene Expression. Bio Protoc. 2021;11(21):e4205doi: 10.21769/BioProtoc.4205.
Rommereim, L., Akhade, A. S., Germain, R. N., Fraser, I. D. C., & Subramanian, N. (2021). Lentivirus-mediated Conditional Gene Expression. Bio-protocol, 11(21), e4205. https://doi.org/10.21769/BioProtoc.4205
Rommereim, Leah, et al. "Lentivirus-mediated Conditional Gene Expression." Bio-protocol vol. 11,21 (2021): e4205. doi: https://doi.org/10.21769/BioProtoc.4205
Rommereim L, Akhade AS, Germain RN, Fraser IDC, Subramanian N. Lentivirus-mediated Conditional Gene Expression. Bio Protoc. 2021 Nov 05;11(21):e4205. doi: 10.21769/BioProtoc.4205. eCollection 2021 Nov 05. PMID: 34859120; PMCID: PMC8595424.
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Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches.

Clinical kidney journal

Lipman ZM, Paramasivam V, Yosipovitch G, Germain MJ.
PMID: 34987779
Clin Kidney J. 2021 Oct 14;14:i16-i22. doi: 10.1093/ckj/sfab167. eCollection 2021 Dec.

Chronic kidney disease (CKD)-associated pruritus (CKD-aP) is an underdiagnosed yet severely distressing condition that impacts 60% of patients on dialysis and many nondialysis patients with Stages 3-5 CKD. However, despite its high prevalence, there are currently limited treatment options...

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Lipman ZM, Paramasivam V, Yosipovitch G, et al. Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches. Clin Kidney J. 2021;14:i16-i22doi: 10.1093/ckj/sfab167.
Lipman, Z. M., Paramasivam, V., Yosipovitch, G., & Germain, M. J. (2021). Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches. Clinical kidney journal, 14i16-i22. https://doi.org/10.1093/ckj/sfab167
Lipman, Zoe M, et al. "Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches." Clinical kidney journal vol. 14 (2021): i16-i22. doi: https://doi.org/10.1093/ckj/sfab167
Lipman ZM, Paramasivam V, Yosipovitch G, Germain MJ. Clinical management of chronic kidney disease-associated pruritus: current treatment options and future approaches. Clin Kidney J. 2021 Oct 14;14:i16-i22. doi: 10.1093/ckj/sfab167. eCollection 2021 Dec. PMID: 34987779; PMCID: PMC8702820.
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Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing.

The Journal of pathology

Dixon K, Brew T, Farnell D, Godwin TD, Cheung S, Chow C, Ta M, Ho G, Bui M, Douglas JM, Campbell KR, El-Naggar A, Kaurah P, Kalloger SE, Lim HJ, Schaeffer DF, Cochrane D, Guilford P, Huntsman DG.
PMID: 33797756
J Pathol. 2021 Jul;254(3):254-264. doi: 10.1002/path.5675. Epub 2021 May 12.

Hereditary diffuse gastric cancer (HDGC) is a cancer syndrome caused by germline variants in CDH1, the gene encoding the cell-cell adhesion molecule E-cadherin. Loss of E-cadherin in cancer is associated with cellular dedifferentiation and poor prognosis, but the mechanisms...

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Dixon K, Brew T, Farnell D, et al. Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing. J Pathol. 2021;254(3):254-264doi: 10.1002/path.5675.
Dixon, K., Brew, T., Farnell, D., Godwin, T. D., Cheung, S., Chow, C., Ta, M., Ho, G., Bui, M., Douglas, J. M., Campbell, K. R., El-Naggar, A., Kaurah, P., Kalloger, S. E., Lim, H. J., Schaeffer, D. F., Cochrane, D., Guilford, P., & Huntsman, D. G. (2021). Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing. The Journal of pathology, 254(3), 254-264. https://doi.org/10.1002/path.5675
Dixon, Katherine, et al. "Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing." The Journal of pathology vol. 254,3 (2021): 254-264. doi: https://doi.org/10.1002/path.5675
Dixon K, Brew T, Farnell D, Godwin TD, Cheung S, Chow C, Ta M, Ho G, Bui M, Douglas JM, Campbell KR, El-Naggar A, Kaurah P, Kalloger SE, Lim HJ, Schaeffer DF, Cochrane D, Guilford P, Huntsman DG. Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing. J Pathol. 2021 Jul;254(3):254-264. doi: 10.1002/path.5675. Epub 2021 May 12. PMID: 33797756.
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The gamble on high risk students.

Toxicon : official journal of the International Society on Toxinology

Germain LD.
PMID: 5495999
Toxicon. 1970 Sep;8(3):2-3 passim.

No abstract available.

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Germain LD. The gamble on high risk students. Toxicon. 1970;8(3):2-3 passim
Germain, L. D. (1970). The gamble on high risk students. Toxicon : official journal of the International Society on Toxinology, 8(3), 2-3 passim.
Germain, L D. "The gamble on high risk students." Toxicon : official journal of the International Society on Toxinology vol. 8,3 (1970): 2-3 passim.
Germain LD. The gamble on high risk students. Toxicon. 1970 Sep;8(3):2-3 passim. PMID: 5495999.
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Showing 25 to 36 of 160 entries