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Showing 625 to 634 of 634 entries
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Clostridioides difficile Infection in a Rural New Zealand Secondary Care Centre: An Incidence Case-Control Study.

Internal medicine journal

Johnston M, Irwin J, Roberts S, Leung A, Andersson HS, Orme G, Deroles-Main J, Bakker S.
PMID: 33528096
Intern Med J. 2021 Feb 02; doi: 10.1111/imj.15220. Epub 2021 Feb 02.

BACKGROUND: Clostridioides difficile Infection (CDI) is a form of antibiotic associated infectious diarrhoea resulting in significant morbidity and mortality. Community acquired disease in low risk individuals is increasingly recognised. There are limited New Zealand data published.AIM: To determine the...

Lessons Learned From Implementation of a "Geriatric-Friendly" Admission Order Set.

The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians

Peck A, Irwin AN.
PMID: 34860977
J Pharm Technol. 2018 Aug;34(4):181-182. doi: 10.1177/8755122518769935. Epub 2018 Apr 16.

No abstract available.

A randomized controlled study of convalescent plasma for individuals hospitalized with COVID-19 pneumonia.

The Journal of clinical investigation

Bar KJ, Shaw PA, Choi GH, Aqui N, Fesnak A, Yang JB, Soto-Calderon H, Grajales L, Starr J, Andronov M, Mastellone M, Amonu C, Feret G, DeMarshall M, Buchanan M, Caturla M, Gordon J, Wanicur A, Monroy MA, Mampe F, Lindemuth E, Gouma S, Mullin AM, Barilla H, Pronina A, Irwin L, Thomas R, Eichinger RA, Demuth F, Luning Prak ET, Pascual JL, Short WR, Elovitz MA, Baron J, Meyer NJ, Degnan KO, Frank I, Hensley SE, Siegel DL, Tebas P.
PMID: 34788233
J Clin Invest. 2021 Dec 15;131(24). doi: 10.1172/JCI155114.

BackgroundAntibody-based strategies for COVID-19 have shown promise in prevention and treatment of early disease. COVID-19 convalescent plasma (CCP) has been widely used but results from randomized trials supporting its benefit in hospitalized patients with pneumonia are limited. Here, we...

Cellular mechanism of bile acid-accelerated hepatocyte polarity.

Small GTPases

Fu D, Lippincott-Schwartz J, Arias IM.
PMID: 22545229
Small GTPases. 2011 Nov 01;2(6):314-317. doi: 10.4161/sgtp.18087.

We recently discovered that the major mammalian bile acid, taurocholate, accelerated polarity in primary rat hepatocytes. Taurocholate increased cellular cAMP and signals through an Epac-Rap1-MEK-LKB1-AMPK pathway for its polarity effect. This review discusses possible mechanisms for how taurocholate affects...

2D single crystal Bragg-dip mapping by time-of-flight energy-resolved neutron imaging on IMAT@ISIS.

Scientific reports

Strickland J, Tassenberg K, Sheppard G, Nenchev B, Perry S, Li J, Dong H, Burca G, Kelleher J, Irwin S.
PMID: 33247196
Sci Rep. 2020 Nov 27;10(1):20751. doi: 10.1038/s41598-020-77572-3.

The cold neutron imaging and diffraction instrument IMAT, at the second target station of the pulsed neutron and muon source ISIS, is used to investigate bulk mosaicity within as-cast single crystal CMSX-4 and CMSX-10 Ni-base superalloys. Within this study,...

Continuity of Cancer Care: The Surgical Experience of Two Large Cancer Hubs in London and Milan.

Cancers

Monroy-Iglesias MJ, Tagliabue M, Dickinson H, Roberts G, De Berardinis R, Russell B, Moss C, Irwin S, Olsburgh J, Cocco IMF, Schizas A, McCrindle S, Nath R, Brunet A, Simo R, Tornari C, Srinivasan P, Prachalias A, Davies A, Geh J, Fraser S, Routledge T, Ma R, Doerge E, Challacombe B, Nair R, Hadjipavlou M, Scarpinata R, Sorelli P, Dolly S, Mistretta FA, Musi G, Casiraghi M, Aloisi A, Dell'Acqua A, Scaglione D, Zanoni S, Rampazio Da Silva D, Brambilla D, Bertolotti R, Peruzzotti G, Maggioni A, de Cobelli O, Spaggiari L, Ansarin M, Mastrilli F, Gandini S, Jain U, Hamed H, Haire K, Van Hemelrijck M.
PMID: 33808375
Cancers (Basel). 2021 Mar 30;13(7). doi: 10.3390/cancers13071597.

The SARS-CoV-2 (COVID-19) pandemic is having a large effect on the management of cancer patients. This study reports on the approach and outcomes of cancer patients receiving radical surgery with curative intent between March and September 2020 (in comparison...

A proposed framework for the development and qualitative evaluation of West Nile virus models and their application to local public health decision-making.

PLoS neglected tropical diseases

Keyel AC, Gorris ME, Rochlin I, Uelmen JA, Chaves LF, Hamer GL, Moise IK, Shocket M, Kilpatrick AM, DeFelice NB, Davis JK, Little E, Irwin P, Tyre AJ, Helm Smith K, Fredregill CL, Elison Timm O, Holcomb KM, Wimberly MC, Ward MJ, Barker CM, Rhodes CG, Smith RL.
PMID: 34499656
PLoS Negl Trop Dis. 2021 Sep 09;15(9):e0009653. doi: 10.1371/journal.pntd.0009653. eCollection 2021 Sep.

West Nile virus (WNV) is a globally distributed mosquito-borne virus of great public health concern. The number of WNV human cases and mosquito infection patterns vary in space and time. Many statistical models have been developed to understand and...

Biological Mechanisms for Cartilage Repair Using a BioCartilage Scaffold: Cellular Adhesion/Migration and Bioactive Proteins.

Cartilage

Commins J, Irwin R, Matuska A, Goodale M, Delco M, Fortier L.
PMID: 31965816
Cartilage. 2021 Dec;13(1):984S-992S. doi: 10.1177/1947603519900803. Epub 2020 Jan 22.

No abstract available.

Reducing salt intake: a systematic review and meta-analysis of behavior change interventions in adults.

Nutrition reviews

Khalesi S, Williams E, Irwin C, Johnson DW, Webster J, McCartney D, Jamshidi A, Vandelanotte C.
PMID: 34921314
Nutr Rev. 2021 Dec 17; doi: 10.1093/nutrit/nuab110. Epub 2021 Dec 17.

CONTEXT: Prolonged high salt (sodium) intake can increase the risk of hypertension and cardiovascular disease. Behavioral interventions may help reduce sodium intake at the population level.OBJECTIVE: The effectiveness of behavior change interventions to reduce sodium intake in adults was...

Effects of Vitamin D Supplementation on Insulin Sensitivity and Secretion in Prediabetes.

The Journal of clinical endocrinology and metabolism

Rasouli N, Brodsky IG, Chatterjee R, Kim SH, Pratley RE, Staten MA, Pittas AG.
PMID: 34473295
J Clin Endocrinol Metab. 2022 Jan 01;107(1):230-240. doi: 10.1210/clinem/dgab649.

CONTEXT: Vitamin D regulates glucose homeostasis pathways, but effects of vitamin D supplementation on β-cell function remain unclear.OBJECTIVE: To investigate the effects of vitamin D3 supplementation on insulin sensitivity and β-cell function.METHODS: This is a prespecified secondary analysis of...

Showing 625 to 634 of 634 entries