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An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action.

F1000Research

Anzt H, Bach F, Druskat S, Löffler F, Loewe A, Renard BY, Seemann G, Struck A, Achhammer E, Aggarwal P, Appel F, Bader M, Brusch L, Busse C, Chourdakis G, Dabrowski PW, Ebert P, Flemisch B, Friedl S, Fritzsch B, Funk MD, Gast V, Goth F, Grad JN, Hegewald J, Hermann S, Hohmann F, Janosch S, Kutra D, Linxweiler J, Muth T, Peters-Kottig W, Rack F, Raters FHC, Rave S, Reina G, Reißig M, Ropinski T, Schaarschmidt J, Seibold H, Thiele JP, Uekermann B, Unger S, Weeber R.
PMID: 33552475
F1000Res. 2020 Apr 27;9:295. doi: 10.12688/f1000research.23224.2. eCollection 2020.

Research software has become a central asset in academic research. It optimizes existing and enables new research methods, implements and embeds research knowledge, and constitutes an essential research product in itself. Research software must be sustainable in order to...

Cite
Anzt H, Bach F, Druskat S, et al. An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action. F1000Res. 2020;9:295doi: 10.12688/f1000research.23224.2.
Anzt, H., Bach, F., Druskat, S., Löffler, F., Loewe, A., Renard, B. Y., Seemann, G., Struck, A., Achhammer, E., Aggarwal, P., Appel, F., Bader, M., Brusch, L., Busse, C., Chourdakis, G., Dabrowski, P. W., Ebert, P., Flemisch, B., Friedl, S., Fritzsch, B., Funk, M. D., Gast, V., Goth, F., Grad, J. N., Hegewald, J., Hermann, S., Hohmann, F., Janosch, S., Kutra, D., Linxweiler, J., Muth, T., Peters-Kottig, W., Rack, F., Raters, F. H. C., Rave, S., Reina, G., Reißig, M., Ropinski, T., Schaarschmidt, J., Seibold, H., Thiele, J. P., Uekermann, B., Unger, S., & Weeber, R. (2020). An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action. F1000Research, 9295. https://doi.org/10.12688/f1000research.23224.2
Anzt, Hartwig, et al. "An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action." F1000Research vol. 9 (2020): 295. doi: https://doi.org/10.12688/f1000research.23224.2
Anzt H, Bach F, Druskat S, Löffler F, Loewe A, Renard BY, Seemann G, Struck A, Achhammer E, Aggarwal P, Appel F, Bader M, Brusch L, Busse C, Chourdakis G, Dabrowski PW, Ebert P, Flemisch B, Friedl S, Fritzsch B, Funk MD, Gast V, Goth F, Grad JN, Hegewald J, Hermann S, Hohmann F, Janosch S, Kutra D, Linxweiler J, Muth T, Peters-Kottig W, Rack F, Raters FHC, Rave S, Reina G, Reißig M, Ropinski T, Schaarschmidt J, Seibold H, Thiele JP, Uekermann B, Unger S, Weeber R. An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action. F1000Res. 2020 Apr 27;9:295. doi: 10.12688/f1000research.23224.2. eCollection 2020. PMID: 33552475; PMCID: PMC7845155.
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S2k guideline diagnosis and treatment of carbon monoxide poisoning.

German medical science : GMS e-journal

Jüttner B, Busch HJ, Callies A, Dormann H, Janisch T, Kaiser G, Körner-Göbel H, Kluba K, Kluge S, Leidel BA, Müller O, Naser J, Pohl C, Reiter K, Schneider D, Staps E, Welslau W, Wißuwa H, Wöbker G, Muche-Borowski C.
PMID: 34867135
Ger Med Sci. 2021 Nov 04;19:Doc13. doi: 10.3205/000300. eCollection 2021.

Carbon monoxide (CO) can occur in numerous situations and ambient conditions, such as fire smoke, indoor fireplaces, silos containing large quantities of wood pellets, engine exhaust fumes, and when using hookahs. Symptoms of CO poisoning are nonspecific and can...

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Jüttner B, Busch HJ, Callies A, et al. S2k guideline diagnosis and treatment of carbon monoxide poisoning. Ger Med Sci. 2021;19:Doc13doi: 10.3205/000300.
Jüttner, B., Busch, H. J., Callies, A., Dormann, H., Janisch, T., Kaiser, G., Körner-Göbel, H., Kluba, K., Kluge, S., Leidel, B. A., Müller, O., Naser, J., Pohl, C., Reiter, K., Schneider, D., Staps, E., Welslau, W., Wißuwa, H., Wöbker, G., & Muche-Borowski, C. (2021). S2k guideline diagnosis and treatment of carbon monoxide poisoning. German medical science : GMS e-journal, 19Doc13. https://doi.org/10.3205/000300
Jüttner, Björn, et al. "S2k guideline diagnosis and treatment of carbon monoxide poisoning." German medical science : GMS e-journal vol. 19 (2021): Doc13. doi: https://doi.org/10.3205/000300
Jüttner B, Busch HJ, Callies A, Dormann H, Janisch T, Kaiser G, Körner-Göbel H, Kluba K, Kluge S, Leidel BA, Müller O, Naser J, Pohl C, Reiter K, Schneider D, Staps E, Welslau W, Wißuwa H, Wöbker G, Muche-Borowski C. S2k guideline diagnosis and treatment of carbon monoxide poisoning. Ger Med Sci. 2021 Nov 04;19:Doc13. doi: 10.3205/000300. eCollection 2021. PMID: 34867135; PMCID: PMC8607608.
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Administration of a VEGFR‑2-specific MRI contrast agent to assess orthodontic tooth movement : A pilot study.

Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie

Schröder A, Seyler L, Hofmann E, Gölz L, Jantsch J, Proff P, Bäuerle T, Kirschneck C.
PMID: 34269823
J Orofac Orthop. 2021 Jul 16; doi: 10.1007/s00056-021-00326-x. Epub 2021 Jul 16.

PURPOSE: It is thought that orthodontic forces initially reduce periodontal blood flow during orthodontic tooth movement (OTM) via tissue compression with cells responding to concomitant oxygen deprivation with expression of vascular endothelial growth factor (VEGF) triggering angiogenesis via binding...

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Schröder A, Seyler L, Hofmann E, et al. Verabreichung eines VEGFR‑2-spezifischen MRT-Kontrastmittels zur Beurteilung der kieferorthopädischen Zahnbewegung : Eine Pilotstudie. Administration of a VEGFR‑2-specific MRI contrast agent to assess orthodontic tooth movement : A pilot study. J Orofac Orthop. 2021;doi: 10.1007/s00056-021-00326-x.
Schröder, A., Seyler, L., Hofmann, E., Gölz, L., Jantsch, J., Proff, P., Bäuerle, T., & Kirschneck, C. (2021). Verabreichung eines VEGFR‑2-spezifischen MRT-Kontrastmittels zur Beurteilung der kieferorthopädischen Zahnbewegung : Eine Pilotstudie. Administration of a VEGFR‑2-specific MRI contrast agent to assess orthodontic tooth movement : A pilot study. Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, . https://doi.org/10.1007/s00056-021-00326-x
Schröder, Agnes, et al. "Verabreichung eines VEGFR‑2-spezifischen MRT-Kontrastmittels zur Beurteilung der kieferorthopädischen Zahnbewegung : Eine Pilotstudie." Administration of a VEGFR‑2-specific MRI contrast agent to assess orthodontic tooth movement : A pilot study. Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie vol. (2021). doi: https://doi.org/10.1007/s00056-021-00326-x
Schröder A, Seyler L, Hofmann E, Gölz L, Jantsch J, Proff P, Bäuerle T, Kirschneck C. Verabreichung eines VEGFR‑2-spezifischen MRT-Kontrastmittels zur Beurteilung der kieferorthopädischen Zahnbewegung : Eine Pilotstudie. Administration of a VEGFR‑2-specific MRI contrast agent to assess orthodontic tooth movement : A pilot study. J Orofac Orthop. 2021 Jul 16; doi: 10.1007/s00056-021-00326-x. Epub 2021 Jul 16. PMID: 34269823.
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A mechanism-based group-psychotherapy approach to aggressive behaviour in borderline personality disorder: findings from a cluster-randomised controlled trial.

BJPsych open

Herpertz SC, Matzke B, Hillmann K, Neukel C, Mancke F, Jaentsch B, Schwenger U, Honecker H, Bullenkamp R, Steinmann S, Krauch M, Bauer S, Borzikowsky C, Bertsch K, Dempfle A.
PMID: 33308363
BJPsych Open. 2020 Dec 14;7(1):e17. doi: 10.1192/bjo.2020.131.

BACKGROUND: Aggressive behaviour is a prevalent and harmful phenomenon in patients with borderline personality disorder (BPD). However, no short-term, low-cost programme exists that specifically focuses on aggression.AIMS: Attuning therapy modules to pathogenetic mechanisms that underlie reactive aggression in BPD,...

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Herpertz SC, Matzke B, Hillmann K, et al. A mechanism-based group-psychotherapy approach to aggressive behaviour in borderline personality disorder: findings from a cluster-randomised controlled trial. BJPsych Open. 2020;7(1):e17doi: 10.1192/bjo.2020.131.
Herpertz, S. C., Matzke, B., Hillmann, K., Neukel, C., Mancke, F., Jaentsch, B., Schwenger, U., Honecker, H., Bullenkamp, R., Steinmann, S., Krauch, M., Bauer, S., Borzikowsky, C., Bertsch, K., & Dempfle, A. (2020). A mechanism-based group-psychotherapy approach to aggressive behaviour in borderline personality disorder: findings from a cluster-randomised controlled trial. BJPsych open, 7(1), e17. https://doi.org/10.1192/bjo.2020.131
Herpertz, S C, et al. "A mechanism-based group-psychotherapy approach to aggressive behaviour in borderline personality disorder: findings from a cluster-randomised controlled trial." BJPsych open vol. 7,1 (2020): e17. doi: https://doi.org/10.1192/bjo.2020.131
Herpertz SC, Matzke B, Hillmann K, Neukel C, Mancke F, Jaentsch B, Schwenger U, Honecker H, Bullenkamp R, Steinmann S, Krauch M, Bauer S, Borzikowsky C, Bertsch K, Dempfle A. A mechanism-based group-psychotherapy approach to aggressive behaviour in borderline personality disorder: findings from a cluster-randomised controlled trial. BJPsych Open. 2020 Dec 14;7(1):e17. doi: 10.1192/bjo.2020.131. PMID: 33308363; PMCID: PMC7791567.
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An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action.

F1000Research

Anzt H, Bach F, Druskat S, Löffler F, Loewe A, Renard BY, Seemann G, Struck A, Achhammer E, Aggarwal P, Appel F, Bader M, Brusch L, Busse C, Chourdakis G, Dabrowski PW, Ebert P, Flemisch B, Friedl S, Fritzsch B, Funk MD, Gast V, Goth F, Grad JN, Hermann S, Hohmann F, Janosch S, Kutra D, Linxweiler J, Muth T, Peters-Kottig W, Rack F, Raters FHC, Rave S, Reina G, Reißig M, Ropinski T, Schaarschmidt J, Seibold H, Thiele JP, Uekermann B, Unger S, Weeber R.
PMID: 33552475
F1000Res. 2020 Apr 27;9:295. doi: 10.12688/f1000research.23224.1. eCollection 2020.

Research software has become a central asset in academic research. It optimizes existing and enables new research methods, implements and embeds research knowledge, and constitutes an essential research product in itself. Research software must be sustainable in order to...

Cite
Anzt H, Bach F, Druskat S, et al. An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action. F1000Res. 2020;9:295doi: 10.12688/f1000research.23224.1.
Anzt, H., Bach, F., Druskat, S., Löffler, F., Loewe, A., Renard, B. Y., Seemann, G., Struck, A., Achhammer, E., Aggarwal, P., Appel, F., Bader, M., Brusch, L., Busse, C., Chourdakis, G., Dabrowski, P. W., Ebert, P., Flemisch, B., Friedl, S., Fritzsch, B., Funk, M. D., Gast, V., Goth, F., Grad, J. N., Hermann, S., Hohmann, F., Janosch, S., Kutra, D., Linxweiler, J., Muth, T., Peters-Kottig, W., Rack, F., Raters, F. H. C., Rave, S., Reina, G., Reißig, M., Ropinski, T., Schaarschmidt, J., Seibold, H., Thiele, J. P., Uekermann, B., Unger, S., & Weeber, R. (2020). An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action. F1000Research, 9295. https://doi.org/10.12688/f1000research.23224.1
Anzt, Hartwig, et al. "An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action." F1000Research vol. 9 (2020): 295. doi: https://doi.org/10.12688/f1000research.23224.1
Anzt H, Bach F, Druskat S, Löffler F, Loewe A, Renard BY, Seemann G, Struck A, Achhammer E, Aggarwal P, Appel F, Bader M, Brusch L, Busse C, Chourdakis G, Dabrowski PW, Ebert P, Flemisch B, Friedl S, Fritzsch B, Funk MD, Gast V, Goth F, Grad JN, Hermann S, Hohmann F, Janosch S, Kutra D, Linxweiler J, Muth T, Peters-Kottig W, Rack F, Raters FHC, Rave S, Reina G, Reißig M, Ropinski T, Schaarschmidt J, Seibold H, Thiele JP, Uekermann B, Unger S, Weeber R. An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action. F1000Res. 2020 Apr 27;9:295. doi: 10.12688/f1000research.23224.1. eCollection 2020. PMID: 33552475; PMCID: PMC7845155.
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Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis.

Circulation. Genomic and precision medicine

Seidel F, Holtgrewe M, Al-Wakeel-Marquard N, Opgen-Rhein B, Dartsch J, Herbst C, Beule D, Pickardt T, Klingel K, Messroghli D, Berger F, Schubert S, Kühnisch J, Klaassen S.
PMID: 34213952
Circ Genom Precis Med. 2021 Aug;14(4):e003250. doi: 10.1161/CIRCGEN.120.003250. Epub 2021 Jul 02.

BACKGROUND: Myocarditis is one of the most common causes leading to heart failure in children and a possible genetic background has been postulated. We sought to characterize the clinical and genetic characteristics in patients with myocarditis ≤18 years of...

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Seidel F, Holtgrewe M, Al-Wakeel-Marquard N, et al. Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis. Circ Genom Precis Med. 2021;14(4):e003250doi: 10.1161/CIRCGEN.120.003250.
Seidel, F., Holtgrewe, M., Al-Wakeel-Marquard, N., Opgen-Rhein, B., Dartsch, J., Herbst, C., Beule, D., Pickardt, T., Klingel, K., Messroghli, D., Berger, F., Schubert, S., Kühnisch, J., & Klaassen, S. (2021). Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis. Circulation. Genomic and precision medicine, 14(4), e003250. https://doi.org/10.1161/CIRCGEN.120.003250
Seidel, Franziska, et al. "Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis." Circulation. Genomic and precision medicine vol. 14,4 (2021): e003250. doi: https://doi.org/10.1161/CIRCGEN.120.003250
Seidel F, Holtgrewe M, Al-Wakeel-Marquard N, Opgen-Rhein B, Dartsch J, Herbst C, Beule D, Pickardt T, Klingel K, Messroghli D, Berger F, Schubert S, Kühnisch J, Klaassen S. Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis. Circ Genom Precis Med. 2021 Aug;14(4):e003250. doi: 10.1161/CIRCGEN.120.003250. Epub 2021 Jul 02. PMID: 34213952; PMCID: PMC8373449.
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Association Between Homeschooling and Adolescent Sleep Duration and Health During COVID-19 Pandemic High School Closures.

JAMA network open

Albrecht JN, Werner H, Rieger N, Widmer N, Janisch D, Huber R, Jenni OG.
PMID: 34985517
JAMA Netw Open. 2022 Jan 04;5(1):e2142100. doi: 10.1001/jamanetworkopen.2021.42100.

IMPORTANCE: Although negative associations of COVID-19 pandemic high school closures with adolescents' health have been demonstrated repeatedly, some research has reported a beneficial association of these closures with adolescents' sleep. The present study was, to our knowledge, the first...

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Albrecht JN, Werner H, Rieger N, et al. Association Between Homeschooling and Adolescent Sleep Duration and Health During COVID-19 Pandemic High School Closures. JAMA Netw Open. 2022;5(1):e2142100doi: 10.1001/jamanetworkopen.2021.42100.
Albrecht, J. N., Werner, H., Rieger, N., Widmer, N., Janisch, D., Huber, R., & Jenni, O. G. (2022). Association Between Homeschooling and Adolescent Sleep Duration and Health During COVID-19 Pandemic High School Closures. JAMA network open, 5(1), e2142100. https://doi.org/10.1001/jamanetworkopen.2021.42100
Albrecht, Joëlle N, et al. "Association Between Homeschooling and Adolescent Sleep Duration and Health During COVID-19 Pandemic High School Closures." JAMA network open vol. 5,1 (2022): e2142100. doi: https://doi.org/10.1001/jamanetworkopen.2021.42100
Albrecht JN, Werner H, Rieger N, Widmer N, Janisch D, Huber R, Jenni OG. Association Between Homeschooling and Adolescent Sleep Duration and Health During COVID-19 Pandemic High School Closures. JAMA Netw Open. 2022 Jan 04;5(1):e2142100. doi: 10.1001/jamanetworkopen.2021.42100. PMID: 34985517.
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Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease: The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial.

JAMA cardiology

Mayer K, Hein-Rothweiler R, Schüpke S, Janisch M, Bernlochner I, Ndrepepa G, Sibbing D, Gori T, Borst O, Holdenrieder S, Kupka D, Petzold T, Bradaric C, Okrojek R, Leistner DM, Trippel TD, Münzel T, Landmesser U, Pieske B, Zeiher AM, Gawaz MP, Hapfelmeier A, Laugwitz KL, Schunkert H, Kastrati A, Massberg S.
PMID: 33787834
JAMA Cardiol. 2021 Jul 01;6(7):753-761. doi: 10.1001/jamacardio.2021.0475.

IMPORTANCE: The assessment of new antithrombotic agents with a favorable safety profile is clinically relevant.OBJECTIVE: To test the efficacy and safety of revacept, a novel, lesion-directed antithrombotic drug, acting as a competitive antagonist to platelet glycoprotein VI.DESIGN, SETTING, AND...

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Mayer K, Hein-Rothweiler R, Schüpke S, et al. Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease: The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial. JAMA Cardiol. 2021;6(7):753-761doi: 10.1001/jamacardio.2021.0475.
Mayer, K., Hein-Rothweiler, R., Schüpke, S., Janisch, M., Bernlochner, I., Ndrepepa, G., Sibbing, D., Gori, T., Borst, O., Holdenrieder, S., Kupka, D., Petzold, T., Bradaric, C., Okrojek, R., Leistner, D. M., Trippel, T. D., Münzel, T., Landmesser, U., Pieske, B., Zeiher, A. M., Gawaz, M. P., Hapfelmeier, A., Laugwitz, K. L., Schunkert, H., Kastrati, A., & Massberg, S. (2021). Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease: The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial. JAMA cardiology, 6(7), 753-761. https://doi.org/10.1001/jamacardio.2021.0475
Mayer, Katharina, et al. "Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease: The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial." JAMA cardiology vol. 6,7 (2021): 753-761. doi: https://doi.org/10.1001/jamacardio.2021.0475
Mayer K, Hein-Rothweiler R, Schüpke S, Janisch M, Bernlochner I, Ndrepepa G, Sibbing D, Gori T, Borst O, Holdenrieder S, Kupka D, Petzold T, Bradaric C, Okrojek R, Leistner DM, Trippel TD, Münzel T, Landmesser U, Pieske B, Zeiher AM, Gawaz MP, Hapfelmeier A, Laugwitz KL, Schunkert H, Kastrati A, Massberg S. Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease: The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial. JAMA Cardiol. 2021 Jul 01;6(7):753-761. doi: 10.1001/jamacardio.2021.0475. PMID: 33787834; PMCID: PMC8014195.
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