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Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I.

FEBS open bio

Kern S, Feng HZ, Wei H, Cala S, Jin JP.
PMID: 24319652
FEBS Open Bio. 2013 Nov 23;4:11-7. doi: 10.1016/j.fob.2013.11.002. eCollection 2013.

We previously reported that a restrictive N-terminal truncation of cardiac troponin I (cTnI-ND) is up-regulated in the heart in adaptation to hemodynamic stresses. Over-expression of cTnI-ND in the hearts of transgenic mice revealed functional benefits such as increased relaxation...

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Kern S, Feng HZ, Wei H, et al. Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I. FEBS Open Bio. 2013;4:11-7doi: 10.1016/j.fob.2013.11.002.
Kern, S., Feng, H. Z., Wei, H., Cala, S., & Jin, J. P. (2013). Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I. FEBS open bio, 411-7. https://doi.org/10.1016/j.fob.2013.11.002
Kern, Stephanie, et al. "Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I." FEBS open bio vol. 4 (2013): 11-7. doi: https://doi.org/10.1016/j.fob.2013.11.002
Kern S, Feng HZ, Wei H, Cala S, Jin JP. Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I. FEBS Open Bio. 2013 Nov 23;4:11-7. doi: 10.1016/j.fob.2013.11.002. eCollection 2013. PMID: 24319652; PMCID: PMC3851183.
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Evolution and intelligent design in drug development.

Frontiers in molecular biosciences

Agafonov RV, Wilson C, Kern D.
PMID: 26052517
Front Mol Biosci. 2015 May 21;2:27. doi: 10.3389/fmolb.2015.00027. eCollection 2015.

Sophisticated protein kinase networks, empowering complexity in higher organisms, are also drivers of devastating diseases such as cancer. Accordingly, these enzymes have become major drug targets of the twenty-first century. However, the holy grail of designing specific kinase inhibitors...

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Agafonov RV, Wilson C, Kern D. Evolution and intelligent design in drug development. Front Mol Biosci. 2015;2:27doi: 10.3389/fmolb.2015.00027.
Agafonov, R. V., Wilson, C., & Kern, D. (2015). Evolution and intelligent design in drug development. Frontiers in molecular biosciences, 227. https://doi.org/10.3389/fmolb.2015.00027
Agafonov, Roman V, et al. "Evolution and intelligent design in drug development." Frontiers in molecular biosciences vol. 2 (2015): 27. doi: https://doi.org/10.3389/fmolb.2015.00027
Agafonov RV, Wilson C, Kern D. Evolution and intelligent design in drug development. Front Mol Biosci. 2015 May 21;2:27. doi: 10.3389/fmolb.2015.00027. eCollection 2015. PMID: 26052517; PMCID: PMC4440380.
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Remotely Controlled Isomer Selective Molecular Switching.

Nano letters

Schendel V, Borca B, Pentegov I, Michnowicz T, Kraft U, Klauk H, Wahl P, Schlickum U, Kern K.
PMID: 26619213
Nano Lett. 2016 Jan 13;16(1):93-7. doi: 10.1021/acs.nanolett.5b02974. Epub 2015 Dec 04.

Nonlocal addressing-the "remote control"-of molecular switches promises more efficient processing for information technology, where fast speed of switching is essential. The surface state of the (111) facets of noble metals, a confined two-dimensional electron gas, provides a medium that...

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Schendel V, Borca B, Pentegov I, et al. Remotely Controlled Isomer Selective Molecular Switching. Nano Lett. 2015;16(1):93-7doi: 10.1021/acs.nanolett.5b02974.
Schendel, V., Borca, B., Pentegov, I., Michnowicz, T., Kraft, U., Klauk, H., Wahl, P., Schlickum, U., & Kern, K. (2016). Remotely Controlled Isomer Selective Molecular Switching. Nano letters, 16(1), 93-7. https://doi.org/10.1021/acs.nanolett.5b02974
Schendel, Verena, et al. "Remotely Controlled Isomer Selective Molecular Switching." Nano letters vol. 16,1 (2016): 93-7. doi: https://doi.org/10.1021/acs.nanolett.5b02974
Schendel V, Borca B, Pentegov I, Michnowicz T, Kraft U, Klauk H, Wahl P, Schlickum U, Kern K. Remotely Controlled Isomer Selective Molecular Switching. Nano Lett. 2016 Jan 13;16(1):93-7. doi: 10.1021/acs.nanolett.5b02974. Epub 2015 Dec 04. PMID: 26619213.
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Predictors of false lumen thrombosis in type B aortic dissection treated with TEVAR.

Annals of cardiothoracic surgery

Tolenaar JL, Kern JA, Jonker FH, Cherry KJ, Tracci MC, Angle JF, Sabri S, Trimarchi S, Strider D, Alaiwaidi G, Upchurch GR.
PMID: 24967164
Ann Cardiothorac Surg. 2014 May;3(3):255-63. doi: 10.3978/j.issn.2225-319X.2014.05.17.

BACKGROUND: Thoracic endovascular aortic repair (TEVAR) offers a less invasive treatment option in type B aortic dissection (TBAD) patients and its value has been demonstrated in acute and chronic dissection patients. Total false lumen thrombosis (FLT) is associated with...

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Tolenaar JL, Kern JA, Jonker FH, et al. Predictors of false lumen thrombosis in type B aortic dissection treated with TEVAR. Ann Cardiothorac Surg. 2014;3(3):255-63doi: 10.3978/j.issn.2225-319X.2014.05.17.
Tolenaar, J. L., Kern, J. A., Jonker, F. H., Cherry, K. J., Tracci, M. C., Angle, J. F., Sabri, S., Trimarchi, S., Strider, D., Alaiwaidi, G., & Upchurch, G. R. (2014). Predictors of false lumen thrombosis in type B aortic dissection treated with TEVAR. Annals of cardiothoracic surgery, 3(3), 255-63. https://doi.org/10.3978/j.issn.2225-319X.2014.05.17
Tolenaar, Jip L, et al. "Predictors of false lumen thrombosis in type B aortic dissection treated with TEVAR." Annals of cardiothoracic surgery vol. 3,3 (2014): 255-63. doi: https://doi.org/10.3978/j.issn.2225-319X.2014.05.17
Tolenaar JL, Kern JA, Jonker FH, Cherry KJ, Tracci MC, Angle JF, Sabri S, Trimarchi S, Strider D, Alaiwaidi G, Upchurch GR. Predictors of false lumen thrombosis in type B aortic dissection treated with TEVAR. Ann Cardiothorac Surg. 2014 May;3(3):255-63. doi: 10.3978/j.issn.2225-319X.2014.05.17. PMID: 24967164; PMCID: PMC4052404.
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CRYPTIC AND PSEUDO-CRYPTIC DIVERSITY IN DIATOMS-WITH DESCRIPTIONS OF PSEUDO-NITZSCHIA HASLEANA SP. NOV. AND P. FRYXELLIANA SP. NOV.(1).

Journal of phycology

Lundholm N, Bates SS, Baugh KA, Bill BD, Connell LB, Léger C, Trainer VL.
PMID: 27009733
J Phycol. 2012 Apr;48(2):436-54. doi: 10.1111/j.1529-8817.2012.01132.x. Epub 2012 Mar 19.

A high degree of pseudo-cryptic diversity was reported in the well-studied diatom genus Pseudo-nitzschia. Studies off the coast of Washington State revealed the presence of hitherto undescribed diversity of Pseudo-nitzschia. Forty-one clonal strains, representing six different taxa of the...

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Lundholm N, Bates SS, Baugh KA, et al. CRYPTIC AND PSEUDO-CRYPTIC DIVERSITY IN DIATOMS-WITH DESCRIPTIONS OF PSEUDO-NITZSCHIA HASLEANA SP. NOV. AND P. FRYXELLIANA SP. NOV.(1). J Phycol. 2012;48(2):436-54doi: 10.1111/j.1529-8817.2012.01132.x.
Lundholm, N., Bates, S. S., Baugh, K. A., Bill, B. D., Connell, L. B., Léger, C., & Trainer, V. L. (2012). CRYPTIC AND PSEUDO-CRYPTIC DIVERSITY IN DIATOMS-WITH DESCRIPTIONS OF PSEUDO-NITZSCHIA HASLEANA SP. NOV. AND P. FRYXELLIANA SP. NOV.(1). Journal of phycology, 48(2), 436-54. https://doi.org/10.1111/j.1529-8817.2012.01132.x
Lundholm, Nina, et al. "CRYPTIC AND PSEUDO-CRYPTIC DIVERSITY IN DIATOMS-WITH DESCRIPTIONS OF PSEUDO-NITZSCHIA HASLEANA SP. NOV. AND P. FRYXELLIANA SP. NOV.(1)." Journal of phycology vol. 48,2 (2012): 436-54. doi: https://doi.org/10.1111/j.1529-8817.2012.01132.x
Lundholm N, Bates SS, Baugh KA, Bill BD, Connell LB, Léger C, Trainer VL. CRYPTIC AND PSEUDO-CRYPTIC DIVERSITY IN DIATOMS-WITH DESCRIPTIONS OF PSEUDO-NITZSCHIA HASLEANA SP. NOV. AND P. FRYXELLIANA SP. NOV.(1). J Phycol. 2012 Apr;48(2):436-54. doi: 10.1111/j.1529-8817.2012.01132.x. Epub 2012 Mar 19. PMID: 27009733.
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Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease.

Scientific reports

Garitaonandia I, Gonzalez R, Christiansen-Weber T, Abramihina T, Poustovoitov M, Noskov A, Sherman G, Semechkin A, Snyder E, Kern R.
PMID: 27686862
Sci Rep. 2016 Sep 30;6:34478. doi: 10.1038/srep34478.

Human pluripotent stem cells (PSC) have the potential to revolutionize regenerative medicine. However undifferentiated PSC can form tumors and strict quality control measures and safety studies must be conducted before clinical translation. Here we describe preclinical tumorigenicity and biodistribution...

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Garitaonandia I, Gonzalez R, Christiansen-Weber T, et al. Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease. Sci Rep. 2016;6:34478doi: 10.1038/srep34478.
Garitaonandia, I., Gonzalez, R., Christiansen-Weber, T., Abramihina, T., Poustovoitov, M., Noskov, A., Sherman, G., Semechkin, A., Snyder, E., & Kern, R. (2016). Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease. Scientific reports, 634478. https://doi.org/10.1038/srep34478
Garitaonandia, Ibon, et al. "Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease." Scientific reports vol. 6 (2016): 34478. doi: https://doi.org/10.1038/srep34478
Garitaonandia I, Gonzalez R, Christiansen-Weber T, Abramihina T, Poustovoitov M, Noskov A, Sherman G, Semechkin A, Snyder E, Kern R. Neural Stem Cell Tumorigenicity and Biodistribution Assessment for Phase I Clinical Trial in Parkinson's Disease. Sci Rep. 2016 Sep 30;6:34478. doi: 10.1038/srep34478. PMID: 27686862; PMCID: PMC5055076.
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Quantum Brownian Motion at Strong Dissipation Probed by Superconducting Tunnel Junctions.

Physical review letters

Jäck B, Senkpiel J, Etzkorn M, Ankerhold J, Ast CR, Kern K.
PMID: 29053289
Phys Rev Lett. 2017 Oct 06;119(14):147702. doi: 10.1103/PhysRevLett.119.147702. Epub 2017 Oct 04.

We have investigated the phase dynamics of a superconducting tunnel junction at ultralow temperatures in the presence of high damping, where the interaction with environmental degrees of freedom represents the leading energy scale. In this regime, theory predicts the...

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Jäck B, Senkpiel J, Etzkorn M, et al. Quantum Brownian Motion at Strong Dissipation Probed by Superconducting Tunnel Junctions. Phys Rev Lett. 2017;119(14):147702doi: 10.1103/PhysRevLett.119.147702.
Jäck, B., Senkpiel, J., Etzkorn, M., Ankerhold, J., Ast, C. R., & Kern, K. (2017). Quantum Brownian Motion at Strong Dissipation Probed by Superconducting Tunnel Junctions. Physical review letters, 119(14), 147702. https://doi.org/10.1103/PhysRevLett.119.147702
Jäck, Berthold, et al. "Quantum Brownian Motion at Strong Dissipation Probed by Superconducting Tunnel Junctions." Physical review letters vol. 119,14 (2017): 147702. doi: https://doi.org/10.1103/PhysRevLett.119.147702
Jäck B, Senkpiel J, Etzkorn M, Ankerhold J, Ast CR, Kern K. Quantum Brownian Motion at Strong Dissipation Probed by Superconducting Tunnel Junctions. Phys Rev Lett. 2017 Oct 06;119(14):147702. doi: 10.1103/PhysRevLett.119.147702. Epub 2017 Oct 04. PMID: 29053289.
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Funktionelle Elektrostimulation Paraplegischer Patienten.

European journal of translational myology

Kern H.
PMID: 26913132
Eur J Transl Myol. 2014 Jul 08;24(2):2940. doi: 10.4081/ejtm.2014.2940. eCollection 2014 Jul 08.

Functional Electrical Stimulation on Paraplegic Patients. We report on clinical and physiological effects of 8 months Functional Electrical Stimulation (FES) of quadriceps femoris muscle on 16 paraplegic patients. Each patient had muscle biopsies, CT-muscle diameter measurements, knee extension strength...

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Kern H. Funktionelle Elektrostimulation Paraplegischer Patienten. Eur J Transl Myol. 2014;24(2):2940doi: 10.4081/ejtm.2014.2940.
Kern, H. (2014). Funktionelle Elektrostimulation Paraplegischer Patienten. European journal of translational myology, 24(2), 2940. https://doi.org/10.4081/ejtm.2014.2940
Kern, Helmut. "Funktionelle Elektrostimulation Paraplegischer Patienten." European journal of translational myology vol. 24,2 (2014): 2940. doi: https://doi.org/10.4081/ejtm.2014.2940
Kern H. Funktionelle Elektrostimulation Paraplegischer Patienten. Eur J Transl Myol. 2014 Jul 08;24(2):2940. doi: 10.4081/ejtm.2014.2940. eCollection 2014 Jul 08. PMID: 26913132; PMCID: PMC4749008.
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Potential energy-driven spin manipulation via a controllable hydrogen ligand.

Science advances

Jacobson P, Muenks M, Laskin G, Brovko O, Stepanyuk V, Ternes M, Kern K.
PMID: 28439541
Sci Adv. 2017 Apr 14;3(4):e1602060. doi: 10.1126/sciadv.1602060. eCollection 2017 Apr.

Spin-bearing molecules can be stabilized on surfaces and in junctions with desirable properties, such as a net spin that can be adjusted by external stimuli. Using scanning probes, initial and final spin states can be deduced from topographic or...

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Jacobson P, Muenks M, Laskin G, et al. Potential energy-driven spin manipulation via a controllable hydrogen ligand. Sci Adv. 2017;3(4):e1602060doi: 10.1126/sciadv.1602060.
Jacobson, P., Muenks, M., Laskin, G., Brovko, O., Stepanyuk, V., Ternes, M., & Kern, K. (2017). Potential energy-driven spin manipulation via a controllable hydrogen ligand. Science advances, 3(4), e1602060. https://doi.org/10.1126/sciadv.1602060
Jacobson, Peter, et al. "Potential energy-driven spin manipulation via a controllable hydrogen ligand." Science advances vol. 3,4 (2017): e1602060. doi: https://doi.org/10.1126/sciadv.1602060
Jacobson P, Muenks M, Laskin G, Brovko O, Stepanyuk V, Ternes M, Kern K. Potential energy-driven spin manipulation via a controllable hydrogen ligand. Sci Adv. 2017 Apr 14;3(4):e1602060. doi: 10.1126/sciadv.1602060. eCollection 2017 Apr. PMID: 28439541; PMCID: PMC5392040.
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Long- versus Short-Range Scattering in Doped Epitaxial Graphene.

Nano letters

Straßer C, Ludbrook BM, Levy G, Macdonald AJ, Burke SA, Wehling TO, Kern K, Damascelli A, Ast CR.
PMID: 25822076
Nano Lett. 2015 May 13;15(5):2825-9. doi: 10.1021/nl504155f. Epub 2015 Apr 03.

Tuning the electronic properties of graphene by adatom deposition unavoidably introduces disorder into the system, which directly affects the single-particle excitations and electrodynamics. Using angle-resolved photoemission spectroscopy (ARPES) we trace the evolution of disorder in graphene by thallium adatom...

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Straßer C, Ludbrook BM, Levy G, et al. Long- versus Short-Range Scattering in Doped Epitaxial Graphene. Nano Lett. 2015;15(5):2825-9doi: 10.1021/nl504155f.
Straßer, C., Ludbrook, B. M., Levy, G., Macdonald, A. J., Burke, S. A., Wehling, T. O., Kern, K., Damascelli, A., & Ast, C. R. (2015). Long- versus Short-Range Scattering in Doped Epitaxial Graphene. Nano letters, 15(5), 2825-9. https://doi.org/10.1021/nl504155f
Straßer, C, et al. "Long- versus Short-Range Scattering in Doped Epitaxial Graphene." Nano letters vol. 15,5 (2015): 2825-9. doi: https://doi.org/10.1021/nl504155f
Straßer C, Ludbrook BM, Levy G, Macdonald AJ, Burke SA, Wehling TO, Kern K, Damascelli A, Ast CR. Long- versus Short-Range Scattering in Doped Epitaxial Graphene. Nano Lett. 2015 May 13;15(5):2825-9. doi: 10.1021/nl504155f. Epub 2015 Apr 03. PMID: 25822076.
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Local conformational switching of supramolecular networks at the solid/liquid interface.

ACS nano

Cometto FP, Kern K, Lingenfelder M.
PMID: 25857528
ACS Nano. 2015 May 26;9(5):5544-50. doi: 10.1021/acsnano.5b01658. Epub 2015 Apr 15.

We use the electric field in a scanning tunneling microscope to manipulate the transition between open and close packed 2D supramolecular networks of neutral molecules in nonpolar media. We found that while the magnitude of the applied field is...

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Cometto FP, Kern K, Lingenfelder M. Local conformational switching of supramolecular networks at the solid/liquid interface. ACS Nano. 2015;9(5):5544-50doi: 10.1021/acsnano.5b01658.
Cometto, F. P., Kern, K., & Lingenfelder, M. (2015). Local conformational switching of supramolecular networks at the solid/liquid interface. ACS nano, 9(5), 5544-50. https://doi.org/10.1021/acsnano.5b01658
Cometto, Fernando P, et al. "Local conformational switching of supramolecular networks at the solid/liquid interface." ACS nano vol. 9,5 (2015): 5544-50. doi: https://doi.org/10.1021/acsnano.5b01658
Cometto FP, Kern K, Lingenfelder M. Local conformational switching of supramolecular networks at the solid/liquid interface. ACS Nano. 2015 May 26;9(5):5544-50. doi: 10.1021/acsnano.5b01658. Epub 2015 Apr 15. PMID: 25857528.
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Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications 2000-2012.

Globalization and health

Chersich MF, Blaauw D, Dumbaugh M, Penn-Kekana L, Dhana A, Thwala S, Bijlmakers L, Vargas E, Kern E, Becerra-Posada F, Kavanagh J, Mannava P, Mlotshwa L, Becerril-Montekio V, Footman K, Rees H.
PMID: 27338707
Global Health. 2016 Jun 23;12(1):35. doi: 10.1186/s12992-016-0172-x.

BACKGROUND: Researchers in low- and middle-income countries (LMICs) are under-represented in scientific literature. Mapping of authorship of articles can provide an assessment of data ownership and research capacity in LMICs over time and identify variations between different settings.METHODS: Systematic...

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Chersich MF, Blaauw D, Dumbaugh M, et al. Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications 2000-2012. Global Health. 2016;12(1):35doi: 10.1186/s12992-016-0172-x.
Chersich, M. F., Blaauw, D., Dumbaugh, M., Penn-Kekana, L., Dhana, A., Thwala, S., Bijlmakers, L., Vargas, E., Kern, E., Becerra-Posada, F., Kavanagh, J., Mannava, P., Mlotshwa, L., Becerril-Montekio, V., Footman, K., & Rees, H. (2016). Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications 2000-2012. Globalization and health, 12(1), 35. https://doi.org/10.1186/s12992-016-0172-x
Chersich, Matthew F, et al. "Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications 2000-2012." Globalization and health vol. 12,1 (2016): 35. doi: https://doi.org/10.1186/s12992-016-0172-x
Chersich MF, Blaauw D, Dumbaugh M, Penn-Kekana L, Dhana A, Thwala S, Bijlmakers L, Vargas E, Kern E, Becerra-Posada F, Kavanagh J, Mannava P, Mlotshwa L, Becerril-Montekio V, Footman K, Rees H. Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications 2000-2012. Global Health. 2016 Jun 23;12(1):35. doi: 10.1186/s12992-016-0172-x. PMID: 27338707; PMCID: PMC4917998.
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Showing 13 to 24 of 1126 entries