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Showing 25 to 36 of 1657 entries
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Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients.

World journal of hepatology

Tarao K, Tanaka K, Nozaki A, Sato A, Ishii T, Komatsu H, Ikeda T, Komatsu T, Matsushima S, Oshige K.
PMID: 28469810
World J Hepatol. 2017 Apr 18;9(11):544-550. doi: 10.4254/wjh.v9.i11.544.

AIM: To survey the efficacy and safety of dual therapy with daclatasvir and asunaprevir in the elderly hepatitis C virus (HCV) patients multicentricity.METHODS: Interferon-ineligible/intolerant patients and non-responders to previous pegylated-interferon/ribavirin therapy with chronic HCV genotype 1b infection were enrolled....

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Tarao K, Tanaka K, Nozaki A, et al. Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients. World J Hepatol. 2017;9(11):544-550doi: 10.4254/wjh.v9.i11.544.
Tarao, K., Tanaka, K., Nozaki, A., Sato, A., Ishii, T., Komatsu, H., Ikeda, T., Komatsu, T., Matsushima, S., & Oshige, K. (2017). Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients. World journal of hepatology, 9(11), 544-550. https://doi.org/10.4254/wjh.v9.i11.544
Tarao, Kazuo, et al. "Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients." World journal of hepatology vol. 9,11 (2017): 544-550. doi: https://doi.org/10.4254/wjh.v9.i11.544
Tarao K, Tanaka K, Nozaki A, Sato A, Ishii T, Komatsu H, Ikeda T, Komatsu T, Matsushima S, Oshige K. Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients. World J Hepatol. 2017 Apr 18;9(11):544-550. doi: 10.4254/wjh.v9.i11.544. PMID: 28469810; PMCID: PMC5395803.
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Chronic hepatitis B in children in the United States and Canada: international origins place the disease burden on children even in the era of universal vaccination.

Translational pediatrics

Komatsu H, Inui A.
PMID: 26835398
Transl Pediatr. 2016 Jan;5(1):1-4. doi: 10.3978/j.issn.2224-4336.2015.12.08.

No abstract available.

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Komatsu H, Inui A. Chronic hepatitis B in children in the United States and Canada: international origins place the disease burden on children even in the era of universal vaccination. Transl Pediatr. 2016;5(1):1-4doi: 10.3978/j.issn.2224-4336.2015.12.08.
Komatsu, H., & Inui, A. (2016). Chronic hepatitis B in children in the United States and Canada: international origins place the disease burden on children even in the era of universal vaccination. Translational pediatrics, 5(1), 1-4. https://doi.org/10.3978/j.issn.2224-4336.2015.12.08
Komatsu, Haruki, and Inui, Ayano. "Chronic hepatitis B in children in the United States and Canada: international origins place the disease burden on children even in the era of universal vaccination." Translational pediatrics vol. 5,1 (2016): 1-4. doi: https://doi.org/10.3978/j.issn.2224-4336.2015.12.08
Komatsu H, Inui A. Chronic hepatitis B in children in the United States and Canada: international origins place the disease burden on children even in the era of universal vaccination. Transl Pediatr. 2016 Jan;5(1):1-4. doi: 10.3978/j.issn.2224-4336.2015.12.08. PMID: 26835398; PMCID: PMC4729037.
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Identification of AIM2 as a downstream target of JAK2V617F.

Experimental hematology & oncology

Liew EL, Araki M, Hironaka Y, Mori S, Tan TZ, Morishita S, Edahiro Y, Ohsaka A, Komatsu N.
PMID: 26823993
Exp Hematol Oncol. 2016 Jan 28;5:2. doi: 10.1186/s40164-016-0032-7. eCollection 2015.

BACKGROUND: The gain-of-function mutation JAK2V617F is frequently found in Philadelphia-chromosome-negative myeloproliferative neoplasm (MPN) patients. However, the tumorigenic properties of JAK2V617F have mostly been characterized in in vivo and in vitro murine models due to the lack of appropriate human...

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Liew EL, Araki M, Hironaka Y, et al. Identification of AIM2 as a downstream target of JAK2V617F. Exp Hematol Oncol. 2016;5:2doi: 10.1186/s40164-016-0032-7.
Liew, E. L., Araki, M., Hironaka, Y., Mori, S., Tan, T. Z., Morishita, S., Edahiro, Y., Ohsaka, A., & Komatsu, N. (2015). Identification of AIM2 as a downstream target of JAK2V617F. Experimental hematology & oncology, 52. https://doi.org/10.1186/s40164-016-0032-7
Liew, Ei Leen, et al. "Identification of AIM2 as a downstream target of JAK2V617F." Experimental hematology & oncology vol. 5 (2015): 2. doi: https://doi.org/10.1186/s40164-016-0032-7
Liew EL, Araki M, Hironaka Y, Mori S, Tan TZ, Morishita S, Edahiro Y, Ohsaka A, Komatsu N. Identification of AIM2 as a downstream target of JAK2V617F. Exp Hematol Oncol. 2016 Jan 28;5:2. doi: 10.1186/s40164-016-0032-7. eCollection 2015. PMID: 26823993; PMCID: PMC4730608.
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Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients.

Journal of pharmaceutical health care and sciences

Komatsu T, Morita M, Miyaji F, Inomata T, Ako J, Atsuda K.
PMID: 26819736
J Pharm Health Care Sci. 2015 Sep 25;1:25. doi: 10.1186/s40780-015-0023-6. eCollection 2015.

BACKGROUND: This study aimed to evaluate the population pharmacokinetics of digoxin in Japanese patients and establish a dosage regimen based on the pharmacokinetic data.METHODS: We analyzed 287 serum digoxin samples from 192 individuals by using the nonlinear mixed effects...

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Komatsu T, Morita M, Miyaji F, et al. Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients. J Pharm Health Care Sci. 2015;1:25doi: 10.1186/s40780-015-0023-6.
Komatsu, T., Morita, M., Miyaji, F., Inomata, T., Ako, J., & Atsuda, K. (2015). Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients. Journal of pharmaceutical health care and sciences, 125. https://doi.org/10.1186/s40780-015-0023-6
Komatsu, Toshiaki, et al. "Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients." Journal of pharmaceutical health care and sciences vol. 1 (2015): 25. doi: https://doi.org/10.1186/s40780-015-0023-6
Komatsu T, Morita M, Miyaji F, Inomata T, Ako J, Atsuda K. Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients. J Pharm Health Care Sci. 2015 Sep 25;1:25. doi: 10.1186/s40780-015-0023-6. eCollection 2015. PMID: 26819736; PMCID: PMC4728823.
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Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities.

Journal of clinical biochemistry and nutrition

Murata S, Inoue K, Aomatsu T, Yoden A, Tamai H.
PMID: 28366991
J Clin Biochem Nutr. 2017 Mar;60(2):121-124. doi: 10.3164/jcbn.16-52. Epub 2017 Mar 01.

Carnitine is an essential nutrient for the mitochondrial transport of fatty acids. Carnitine deficiency causes a variety of symptoms in multiple organs. Patients with severe motor and intellectual disabilities often have carnitine deficiency. This study aimed to determine the...

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Murata S, Inoue K, Aomatsu T, et al. Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities. J Clin Biochem Nutr. 2017;60(2):121-124doi: 10.3164/jcbn.16-52.
Murata, S., Inoue, K., Aomatsu, T., Yoden, A., & Tamai, H. (2017). Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities. Journal of clinical biochemistry and nutrition, 60(2), 121-124. https://doi.org/10.3164/jcbn.16-52
Murata, Shinya, et al. "Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities." Journal of clinical biochemistry and nutrition vol. 60,2 (2017): 121-124. doi: https://doi.org/10.3164/jcbn.16-52
Murata S, Inoue K, Aomatsu T, Yoden A, Tamai H. Supplementation with carnitine reduces the severity of constipation: a retrospective study of patients with severe motor and intellectual disabilities. J Clin Biochem Nutr. 2017 Mar;60(2):121-124. doi: 10.3164/jcbn.16-52. Epub 2017 Mar 01. PMID: 28366991; PMCID: PMC5370531.
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Wheat proteomics: proteome modulation and abiotic stress acclimation.

Frontiers in plant science

Komatsu S, Kamal AH, Hossain Z.
PMID: 25538718
Front Plant Sci. 2014 Dec 08;5:684. doi: 10.3389/fpls.2014.00684. eCollection 2014.

Cellular mechanisms of stress sensing and signaling represent the initial plant responses to adverse conditions. The development of high-throughput "Omics" techniques has initiated a new era of the study of plant molecular strategies for adapting to environmental changes. However,...

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Komatsu S, Kamal AH, Hossain Z. Wheat proteomics: proteome modulation and abiotic stress acclimation. Front Plant Sci. 2014;5:684doi: 10.3389/fpls.2014.00684.
Komatsu, S., Kamal, A. H., & Hossain, Z. (2014). Wheat proteomics: proteome modulation and abiotic stress acclimation. Frontiers in plant science, 5684. https://doi.org/10.3389/fpls.2014.00684
Komatsu, Setsuko, et al. "Wheat proteomics: proteome modulation and abiotic stress acclimation." Frontiers in plant science vol. 5 (2014): 684. doi: https://doi.org/10.3389/fpls.2014.00684
Komatsu S, Kamal AH, Hossain Z. Wheat proteomics: proteome modulation and abiotic stress acclimation. Front Plant Sci. 2014 Dec 08;5:684. doi: 10.3389/fpls.2014.00684. eCollection 2014. PMID: 25538718; PMCID: PMC4259124.
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Highly frequent and enhanced injection site reaction induced by peripheral venous injection of fosaprepitant in anthracycline-treated patients.

Journal of Cancer

Sato Y, Kondo M, Inagaki A, Komatsu H, Okada C, Naruse K, Sahashi T, Kuroda J, Ogura H, Uegaki S, Yoshida T, Mori Y, Sawada H, Watanabe S, Sugiura H, Endo Y, Yoshimoto N, Toyama T, Iida S, Yamada K, Kimura K, Wakita A.
PMID: 24799957
J Cancer. 2014 Apr 24;5(5):390-7. doi: 10.7150/jca.7706. eCollection 2014.

BACKGROUND: Fosaprepitant-associated injection site reaction (ISR) has been reported in patients treated with cisplatin, an irritant drug. We conducted this retrospective study to clarify the incidence and symptoms of fosaprepitant-associated ISR in patients treated with anthracycline.PATIENTS AND METHODS: Fifty...

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Sato Y, Kondo M, Inagaki A, et al. Highly frequent and enhanced injection site reaction induced by peripheral venous injection of fosaprepitant in anthracycline-treated patients. J Cancer. 2014;5(5):390-7doi: 10.7150/jca.7706.
Sato, Y., Kondo, M., Inagaki, A., Komatsu, H., Okada, C., Naruse, K., Sahashi, T., Kuroda, J., Ogura, H., Uegaki, S., Yoshida, T., Mori, Y., Sawada, H., Watanabe, S., Sugiura, H., Endo, Y., Yoshimoto, N., Toyama, T., Iida, S., Yamada, K., Kimura, K., & Wakita, A. (2014). Highly frequent and enhanced injection site reaction induced by peripheral venous injection of fosaprepitant in anthracycline-treated patients. Journal of Cancer, 5(5), 390-7. https://doi.org/10.7150/jca.7706
Sato, Yumiko, et al. "Highly frequent and enhanced injection site reaction induced by peripheral venous injection of fosaprepitant in anthracycline-treated patients." Journal of Cancer vol. 5,5 (2014): 390-7. doi: https://doi.org/10.7150/jca.7706
Sato Y, Kondo M, Inagaki A, Komatsu H, Okada C, Naruse K, Sahashi T, Kuroda J, Ogura H, Uegaki S, Yoshida T, Mori Y, Sawada H, Watanabe S, Sugiura H, Endo Y, Yoshimoto N, Toyama T, Iida S, Yamada K, Kimura K, Wakita A. Highly frequent and enhanced injection site reaction induced by peripheral venous injection of fosaprepitant in anthracycline-treated patients. J Cancer. 2014 Apr 24;5(5):390-7. doi: 10.7150/jca.7706. eCollection 2014. PMID: 24799957; PMCID: PMC4007527.
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Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B.

Hepatology research : the official journal of the Japan Society of Hepatology

Okuhara S, Umemura T, Joshita S, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Yoshizawa K, Katsuyama Y, Ota M, Tanaka E.
PMID: 24308754
Hepatol Res. 2014 Oct;44(10):E172-80. doi: 10.1111/hepr.12287. Epub 2014 Jan 26.

AIM: We sought to clarify the associations between serum cytokines and chemokines, hepatitis B surface antigen (HBsAg), hepatitis B core-related antigen (HBcrAg), and hepatitis B virus (HBV) DNA and response to entecavir therapy in chronic hepatitis B.METHODS: We analyzed...

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Okuhara S, Umemura T, Joshita S, et al. Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B. Hepatol Res. 2014;44(10):E172-80doi: 10.1111/hepr.12287.
Okuhara, S., Umemura, T., Joshita, S., Shibata, S., Kimura, T., Morita, S., Komatsu, M., Matsumoto, A., Yoshizawa, K., Katsuyama, Y., Ota, M., & Tanaka, E. (2014). Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B. Hepatology research : the official journal of the Japan Society of Hepatology, 44(10), E172-80. https://doi.org/10.1111/hepr.12287
Okuhara, Sadahisa, et al. "Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B." Hepatology research : the official journal of the Japan Society of Hepatology vol. 44,10 (2014): E172-80. doi: https://doi.org/10.1111/hepr.12287
Okuhara S, Umemura T, Joshita S, Shibata S, Kimura T, Morita S, Komatsu M, Matsumoto A, Yoshizawa K, Katsuyama Y, Ota M, Tanaka E. Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B. Hepatol Res. 2014 Oct;44(10):E172-80. doi: 10.1111/hepr.12287. Epub 2014 Jan 26. PMID: 24308754.
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The primary prevention of addiction in the physician.

The journal of primary prevention

Virshup B, Coombs RH, Kohatsu W.
PMID: 24258625
J Prim Prev. 1993 Sep;14(1):29-49. doi: 10.1007/BF01324654.

A review of the literature suggests that the causes of addiction in the physician include: 1) a genetic component; 2) a dysfunctional family; 3) a college atmosphere where alcohol is part of the ritual of passage; 4) self-selection of...

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Virshup B, Coombs RH, Kohatsu W. The primary prevention of addiction in the physician. J Prim Prev. 1993;14(1):29-49doi: 10.1007/BF01324654.
Virshup, B., Coombs, R. H., & Kohatsu, W. (1993). The primary prevention of addiction in the physician. The journal of primary prevention, 14(1), 29-49. https://doi.org/10.1007/BF01324654
Virshup, B, et al. "The primary prevention of addiction in the physician." The journal of primary prevention vol. 14,1 (1993): 29-49. doi: https://doi.org/10.1007/BF01324654
Virshup B, Coombs RH, Kohatsu W. The primary prevention of addiction in the physician. J Prim Prev. 1993 Sep;14(1):29-49. doi: 10.1007/BF01324654. PMID: 24258625.
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Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy: analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging.

Journal of echocardiography

Kaga S, Mikami T, Onozuka H, Omotehara S, Abe A, Yamada S, Okada M, Komatsu H, Inoue M, Yokoyama S, Nishida M, Shimizu C, Matsuno K, Tsutsui H.
PMID: 27278227
J Echocardiogr. 2009 Jun;7(2):25-33. doi: 10.1007/s12574-009-0009-1. Epub 2009 May 21.

BACKGROUND: Although several previous studies have suggested the presence of right ventricular (RV) diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM) and those with hypertensive left ventricular hypertrophy (HT-LVH), the mechanisms are still unclear. This study aimed to clarify...

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Kaga S, Mikami T, Onozuka H, et al. Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy: analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging. J Echocardiogr. 2009;7(2):25-33doi: 10.1007/s12574-009-0009-1.
Kaga, S., Mikami, T., Onozuka, H., Omotehara, S., Abe, A., Yamada, S., Okada, M., Komatsu, H., Inoue, M., Yokoyama, S., Nishida, M., Shimizu, C., Matsuno, K., & Tsutsui, H. (2009). Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy: analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging. Journal of echocardiography, 7(2), 25-33. https://doi.org/10.1007/s12574-009-0009-1
Kaga, Sanae, et al. "Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy: analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging." Journal of echocardiography vol. 7,2 (2009): 25-33. doi: https://doi.org/10.1007/s12574-009-0009-1
Kaga S, Mikami T, Onozuka H, Omotehara S, Abe A, Yamada S, Okada M, Komatsu H, Inoue M, Yokoyama S, Nishida M, Shimizu C, Matsuno K, Tsutsui H. Right ventricular diastolic dysfunction in patients with left ventricular hypertrophy: analysis of right ventricular myocardial relaxation using two-dimensional speckle tracking imaging. J Echocardiogr. 2009 Jun;7(2):25-33. doi: 10.1007/s12574-009-0009-1. Epub 2009 May 21. PMID: 27278227.
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Comparison of the hospice systems in the United States, Japan and taiwan.

Asian nursing research

Lee CY, Komatsu H, Zhang W, Chao YF, Kim KK, Kim GS, Cho YH, Ko JS.
PMID: 25031199
Asian Nurs Res (Korean Soc Nurs Sci). 2010 Dec;4(4):163-73. doi: 10.1016/S1976-1317(11)60001-7.

PURPOSE: The aim of hospice care is to provide the best possible quality of life both for people approaching the end of life and for their families and carers. The Korean government has been implementing a pilot project for...

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Lee CY, Komatsu H, Zhang W, et al. Comparison of the hospice systems in the United States, Japan and taiwan. Asian Nurs Res (Korean Soc Nurs Sci). 2010;4(4):163-73doi: 10.1016/S1976-1317(11)60001-7.
Lee, C. Y., Komatsu, H., Zhang, W., Chao, Y. F., Kim, K. K., Kim, G. S., Cho, Y. H., & Ko, J. S. (2010). Comparison of the hospice systems in the United States, Japan and taiwan. Asian nursing research, 4(4), 163-73. https://doi.org/10.1016/S1976-1317(11)60001-7
Lee, Chung Yul, et al. "Comparison of the hospice systems in the United States, Japan and taiwan." Asian nursing research vol. 4,4 (2010): 163-73. doi: https://doi.org/10.1016/S1976-1317(11)60001-7
Lee CY, Komatsu H, Zhang W, Chao YF, Kim KK, Kim GS, Cho YH, Ko JS. Comparison of the hospice systems in the United States, Japan and taiwan. Asian Nurs Res (Korean Soc Nurs Sci). 2010 Dec;4(4):163-73. doi: 10.1016/S1976-1317(11)60001-7. PMID: 25031199.
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Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse.

Journal of toxicologic pathology

Kimura-Kojima H, Unuma K, Funakoshi T, Kato C, Komatsu A, Aki T, Uemura K.
PMID: 27182119
J Toxicol Pathol. 2016 Apr;29(2):131-8. doi: 10.1293/tox.2015-0072. Epub 2016 Jan 17.

The aim of this study was to examine the possible involvement of smooth muscle cell remodeling and the induction of MFG-E8 (milk fat globule protein epidermal growth factor-VIII) in vascular pathophysiology during cocaine administration in cultured cells and rats....

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Kimura-Kojima H, Unuma K, Funakoshi T, et al. Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse. J Toxicol Pathol. 2016;29(2):131-8doi: 10.1293/tox.2015-0072.
Kimura-Kojima, H., Unuma, K., Funakoshi, T., Kato, C., Komatsu, A., Aki, T., & Uemura, K. (2016). Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse. Journal of toxicologic pathology, 29(2), 131-8. https://doi.org/10.1293/tox.2015-0072
Kimura-Kojima, Haruka, et al. "Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse." Journal of toxicologic pathology vol. 29,2 (2016): 131-8. doi: https://doi.org/10.1293/tox.2015-0072
Kimura-Kojima H, Unuma K, Funakoshi T, Kato C, Komatsu A, Aki T, Uemura K. Increased MFG-E8 expression and its implications in the vascular pathophysiology of cocaine abuse. J Toxicol Pathol. 2016 Apr;29(2):131-8. doi: 10.1293/tox.2015-0072. Epub 2016 Jan 17. PMID: 27182119; PMCID: PMC4866001.
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Showing 25 to 36 of 1657 entries