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Global Trends in Type 2 Diabetes, 2007-2017.

JAMA

Williams J, Loeffler M.
PMID: 31638662
JAMA. 2019 Oct 22;322(16):1542. doi: 10.1001/jama.2019.16074.

No abstract available.

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Williams J, Loeffler M. Global Trends in Type 2 Diabetes, 2007-2017. JAMA. 2019;322(16):1542doi: 10.1001/jama.2019.16074.
Williams, J., Loeffler, M. (2019). Global Trends in Type 2 Diabetes, 2007-2017. JAMA, 322(16), 1542. https://doi.org/10.1001/jama.2019.16074
Williams, Joan, et al. "Global Trends in Type 2 Diabetes, 2007-2017." JAMA vol. 322,16 (2019): 1542. doi: https://doi.org/10.1001/jama.2019.16074
Williams J, Loeffler M. Global Trends in Type 2 Diabetes, 2007-2017. JAMA. 2019 Oct 22;322(16):1542. doi: 10.1001/jama.2019.16074. PMID: 31638662.
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Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions.

Materials (Basel, Switzerland)

Loeffler H, Jonitz-Heincke A, Peters K, Mueller-Hilke B, Fiedler T, Bader R, Klinder A.
PMID: 32150886
Materials (Basel). 2020 Mar 05;13(5). doi: 10.3390/ma13051150.

Monocytes and macrophages are the first barrier of the innate immune system, which interact with abrasion and corrosion products, leading to the release of proinflammatory mediators and free reactive molecules. The aim of this study was to understand inflammation-relevant...

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Loeffler H, Jonitz-Heincke A, Peters K, et al. Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions. Materials (Basel). 2020;13(5)doi: 10.3390/ma13051150.
Loeffler, H., Jonitz-Heincke, A., Peters, K., Mueller-Hilke, B., Fiedler, T., Bader, R., & Klinder, A. (2020). Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions. Materials (Basel, Switzerland), 13(5), . https://doi.org/10.3390/ma13051150
Loeffler, Henrike, et al. "Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions." Materials (Basel, Switzerland) vol. 13,5 (2020). doi: https://doi.org/10.3390/ma13051150
Loeffler H, Jonitz-Heincke A, Peters K, Mueller-Hilke B, Fiedler T, Bader R, Klinder A. Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions. Materials (Basel). 2020 Mar 05;13(5). doi: 10.3390/ma13051150. PMID: 32150886; PMCID: PMC7085017.
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Are social conflicts at work associated with depressive symptomatology? Results from the population-based LIFE-Adult-Study.

Journal of occupational medicine and toxicology (London, England)

Zuelke AE, Roehr S, Schroeter ML, Witte AV, Hinz A, Engel C, Enzenbach C, Thiery J, Loeffler M, Villringer A, Riedel-Heller SG.
PMID: 32082403
J Occup Med Toxicol. 2020 Feb 12;15:1. doi: 10.1186/s12995-020-0253-x. eCollection 2020.

BACKGROUND: Psychosocial stressors in the workplace can be detrimental to mental health. Conflicts at work, e.g. aggression, hostility or threats from coworkers, supervisors or customers, can be considered a psychosocial stressor, possibly increasing risk for depressive symptoms. Existing studies,...

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Zuelke AE, Roehr S, Schroeter ML, et al. Are social conflicts at work associated with depressive symptomatology? Results from the population-based LIFE-Adult-Study. J Occup Med Toxicol. 2020;15:1doi: 10.1186/s12995-020-0253-x.
Zuelke, A. E., Roehr, S., Schroeter, M. L., Witte, A. V., Hinz, A., Engel, C., Enzenbach, C., Thiery, J., Loeffler, M., Villringer, A., & Riedel-Heller, S. G. (2020). Are social conflicts at work associated with depressive symptomatology? Results from the population-based LIFE-Adult-Study. Journal of occupational medicine and toxicology (London, England), 151. https://doi.org/10.1186/s12995-020-0253-x
Zuelke, Andrea E, et al. "Are social conflicts at work associated with depressive symptomatology? Results from the population-based LIFE-Adult-Study." Journal of occupational medicine and toxicology (London, England) vol. 15 (2020): 1. doi: https://doi.org/10.1186/s12995-020-0253-x
Zuelke AE, Roehr S, Schroeter ML, Witte AV, Hinz A, Engel C, Enzenbach C, Thiery J, Loeffler M, Villringer A, Riedel-Heller SG. Are social conflicts at work associated with depressive symptomatology? Results from the population-based LIFE-Adult-Study. J Occup Med Toxicol. 2020 Feb 12;15:1. doi: 10.1186/s12995-020-0253-x. eCollection 2020. PMID: 32082403; PMCID: PMC7017627.
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Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value.

Frontiers in neuroscience

Loeffler T, Schilcher I, Flunkert S, Hutter-Paier B.
PMID: 32595447
Front Neurosci. 2020 Jun 11;14:579. doi: 10.3389/fnins.2020.00579. eCollection 2020.

Neurofilament-light chain (NF-L) is a well-known clinical biomarker of many neurodegenerative diseases. By analyzing amyotrophic lateral sclerosis (ALS) patients cerebrospinal fluid (CSF) or plasma, progression of NF-L levels can forecast conversion from the presymptomatic to symptomatic stage and time...

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Loeffler T, Schilcher I, Flunkert S, et al. Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value. Front Neurosci. 2020;14:579doi: 10.3389/fnins.2020.00579.
Loeffler, T., Schilcher, I., Flunkert, S., & Hutter-Paier, B. (2020). Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value. Frontiers in neuroscience, 14579. https://doi.org/10.3389/fnins.2020.00579
Loeffler, Tina, et al. "Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value." Frontiers in neuroscience vol. 14 (2020): 579. doi: https://doi.org/10.3389/fnins.2020.00579
Loeffler T, Schilcher I, Flunkert S, Hutter-Paier B. Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value. Front Neurosci. 2020 Jun 11;14:579. doi: 10.3389/fnins.2020.00579. eCollection 2020. PMID: 32595447; PMCID: PMC7300175.
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Editorial.

Veterinary dermatology

Loeffler A, Roudebush P, Campbell-Motsinger K, Grant D, Outerbridge C.
PMID: 34796562
Vet Dermatol. 2021 Dec;32(6):521-523. doi: 10.1111/vde.13027.

No abstract available.

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Loeffler A, Roudebush P, Campbell-Motsinger K, et al. Editorial. Vet Dermatol. 2021;32(6):521-523doi: 10.1111/vde.13027.
Loeffler, A., Roudebush, P., Campbell-Motsinger, K., Grant, D., & Outerbridge, C. (2021). Editorial. Veterinary dermatology, 32(6), 521-523. https://doi.org/10.1111/vde.13027
Loeffler, Anette, et al. "Editorial." Veterinary dermatology vol. 32,6 (2021): 521-523. doi: https://doi.org/10.1111/vde.13027
Loeffler A, Roudebush P, Campbell-Motsinger K, Grant D, Outerbridge C. Editorial. Vet Dermatol. 2021 Dec;32(6):521-523. doi: 10.1111/vde.13027. PMID: 34796562.
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Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes.

Cerebral cortex (New York, N.Y. : 1991)

Shin J, Ma S, Hofer E, Patel Y, Vosberg DE, Tilley S, Roshchupkin GV, Sousa AMM, Jian X, Gottesman R, Mosley TH, Fornage M, Saba Y, Pirpamer L, Schmidt R, Schmidt H, Carrion-Castillo A, Crivello F, Mazoyer B, Bis JC, Li S, Yang Q, Luciano M, Karama S, Lewis L, Bastin ME, Harris MA, Wardlaw JM, Deary IE, Scholz M, Loeffler M, Witte AV, Beyer F, Villringer A, Armstrong NJ, Mather KA, Ames D, Jiang J, Kwok JB, Schofield PR, Thalamuthu A, Trollor JN, Wright MJ, Brodaty H, Wen W, Sachdev PS, Terzikhan N, Evans TE, Adams HHHH, Ikram MA, Frenzel S, Auwera-Palitschka SV, Wittfeld K, Bülow R, Grabe HJ, Tzourio C, Mishra A, Maingault S, Debette S, Gillespie NA, Franz CE, Kremen WS, Ding L, Jahanshad N, Sestan N, Pausova Z, Seshadri S, Paus T.
PMID: 32198502
Cereb Cortex. 2020 Jun 01;30(7):4121-4139. doi: 10.1093/cercor/bhaa035.

We have carried out meta-analyses of genome-wide association studies (GWAS) (n = 23 784) of the first two principal components (PCs) that group together cortical regions with shared variance in their surface area. PC1 (global) captured variations of most...

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Shin J, Ma S, Hofer E, et al. Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cereb Cortex. 2020;30(7):4121-4139doi: 10.1093/cercor/bhaa035.
Shin, J., Ma, S., Hofer, E., Patel, Y., Vosberg, D. E., Tilley, S., Roshchupkin, G. V., Sousa, A. M. M., Jian, X., Gottesman, R., Mosley, T. H., Fornage, M., Saba, Y., Pirpamer, L., Schmidt, R., Schmidt, H., Carrion-Castillo, A., Crivello, F., Mazoyer, B., Bis, J. C., Li, S., Yang, Q., Luciano, M., Karama, S., Lewis, L., Bastin, M. E., Harris, M. A., Wardlaw, J. M., Deary, I. E., Scholz, M., Loeffler, M., Witte, A. V., Beyer, F., Villringer, A., Armstrong, N. J., Mather, K. A., Ames, D., Jiang, J., Kwok, J. B., Schofield, P. R., Thalamuthu, A., Trollor, J. N., Wright, M. J., Brodaty, H., Wen, W., Sachdev, P. S., Terzikhan, N., Evans, T. E., Adams, H. H. H. H., Ikram, M. A., Frenzel, S., Auwera-Palitschka, S. V., Wittfeld, K., Bülow, R., Grabe, H. J., Tzourio, C., Mishra, A., Maingault, S., Debette, S., Gillespie, N. A., Franz, C. E., Kremen, W. S., Ding, L., Jahanshad, N., Sestan, N., Pausova, Z., Seshadri, S., Paus, T. (2020). Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cerebral cortex (New York, N.Y. : 1991), 30(7), 4121-4139. https://doi.org/10.1093/cercor/bhaa035
Shin, Jean, et al. "Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes." Cerebral cortex (New York, N.Y. : 1991) vol. 30,7 (2020): 4121-4139. doi: https://doi.org/10.1093/cercor/bhaa035
Shin J, Ma S, Hofer E, Patel Y, Vosberg DE, Tilley S, Roshchupkin GV, Sousa AMM, Jian X, Gottesman R, Mosley TH, Fornage M, Saba Y, Pirpamer L, Schmidt R, Schmidt H, Carrion-Castillo A, Crivello F, Mazoyer B, Bis JC, Li S, Yang Q, Luciano M, Karama S, Lewis L, Bastin ME, Harris MA, Wardlaw JM, Deary IE, Scholz M, Loeffler M, Witte AV, Beyer F, Villringer A, Armstrong NJ, Mather KA, Ames D, Jiang J, Kwok JB, Schofield PR, Thalamuthu A, Trollor JN, Wright MJ, Brodaty H, Wen W, Sachdev PS, Terzikhan N, Evans TE, Adams HHHH, Ikram MA, Frenzel S, Auwera-Palitschka SV, Wittfeld K, Bülow R, Grabe HJ, Tzourio C, Mishra A, Maingault S, Debette S, Gillespie NA, Franz CE, Kremen WS, Ding L, Jahanshad N, Sestan N, Pausova Z, Seshadri S, Paus T. Global and Regional Development of the Human Cerebral Cortex: Molecular Architecture and Occupational Aptitudes. Cereb Cortex. 2020 Jun 01;30(7):4121-4139. doi: 10.1093/cercor/bhaa035. PMID: 32198502; PMCID: PMC7947185.
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Topological Properties of Neuromorphic Nanowire Networks.

Frontiers in neuroscience

Loeffler A, Zhu R, Hochstetter J, Li M, Fu K, Diaz-Alvarez A, Nakayama T, Shine JM, Kuncic Z.
PMID: 32210754
Front Neurosci. 2020 Mar 06;14:184. doi: 10.3389/fnins.2020.00184. eCollection 2020.

Graph theory has been extensively applied to the topological mapping of complex networks, ranging from social networks to biological systems. Graph theory has increasingly been applied to neuroscience as a method to explore the fundamental structural and functional properties...

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Loeffler A, Zhu R, Hochstetter J, et al. Topological Properties of Neuromorphic Nanowire Networks. Front Neurosci. 2020;14:184doi: 10.3389/fnins.2020.00184.
Loeffler, A., Zhu, R., Hochstetter, J., Li, M., Fu, K., Diaz-Alvarez, A., Nakayama, T., Shine, J. M., & Kuncic, Z. (2020). Topological Properties of Neuromorphic Nanowire Networks. Frontiers in neuroscience, 14184. https://doi.org/10.3389/fnins.2020.00184
Loeffler, Alon, et al. "Topological Properties of Neuromorphic Nanowire Networks." Frontiers in neuroscience vol. 14 (2020): 184. doi: https://doi.org/10.3389/fnins.2020.00184
Loeffler A, Zhu R, Hochstetter J, Li M, Fu K, Diaz-Alvarez A, Nakayama T, Shine JM, Kuncic Z. Topological Properties of Neuromorphic Nanowire Networks. Front Neurosci. 2020 Mar 06;14:184. doi: 10.3389/fnins.2020.00184. eCollection 2020. PMID: 32210754; PMCID: PMC7069063.
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Influence of microbial in-situ heteropolysaccharide production on textural properties of raw fermented sausages (salami).

Journal of food science and technology

Velasco L, Weiss J, Loeffler M.
PMID: 33568849
J Food Sci Technol. 2021 Feb;58(2):562-570. doi: 10.1007/s13197-020-04568-2. Epub 2020 Jul 17.

The purpose of the study was to investigate the influence of a heteropolysacchride (HePS)-forming lactic acid bacteria (LAB) on the quality attributes of raw fermented sausages. Therefore, salamis with the HePS-producing strain

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Velasco L, Weiss J, Loeffler M. Influence of microbial in-situ heteropolysaccharide production on textural properties of raw fermented sausages (salami). J Food Sci Technol. 2020;58(2):562-570doi: 10.1007/s13197-020-04568-2.
Velasco, L., Weiss, J., & Loeffler, M. (2021). Influence of microbial in-situ heteropolysaccharide production on textural properties of raw fermented sausages (salami). Journal of food science and technology, 58(2), 562-570. https://doi.org/10.1007/s13197-020-04568-2
Velasco, Lina, et al. "Influence of microbial in-situ heteropolysaccharide production on textural properties of raw fermented sausages (salami)." Journal of food science and technology vol. 58,2 (2021): 562-570. doi: https://doi.org/10.1007/s13197-020-04568-2
Velasco L, Weiss J, Loeffler M. Influence of microbial in-situ heteropolysaccharide production on textural properties of raw fermented sausages (salami). J Food Sci Technol. 2021 Feb;58(2):562-570. doi: 10.1007/s13197-020-04568-2. Epub 2020 Jul 17. PMID: 33568849; PMCID: PMC7847887.
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Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation.

The Journal of experimental medicine

Ahmed N, Etzrodt M, Dettinger P, Kull T, Loeffler D, Hoppe PS, Chavez JS, Zhang Y, Camargo Ortega G, Hilsenbeck O, Nakajima H, Pietras EM, Schroeder T.
PMID: 34817548
J Exp Med. 2022 Jan 03;219(1). doi: 10.1084/jem.20202490. Epub 2021 Nov 24.

Transcription factors (TFs) regulate cell fates, and their expression must be tightly regulated. Autoregulation is assumed to regulate many TFs' own expression to control cell fates. Here, we manipulate and quantify the (auto)regulation of PU.1, a TF controlling hematopoietic...

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Ahmed N, Etzrodt M, Dettinger P, et al. Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. J Exp Med. 2021;219(1)doi: 10.1084/jem.20202490.
Ahmed, N., Etzrodt, M., Dettinger, P., Kull, T., Loeffler, D., Hoppe, P. S., Chavez, J. S., Zhang, Y., Camargo Ortega, G., Hilsenbeck, O., Nakajima, H., Pietras, E. M., & Schroeder, T. (2022). Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. The Journal of experimental medicine, 219(1), . https://doi.org/10.1084/jem.20202490
Ahmed, Nouraiz, et al. "Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation." The Journal of experimental medicine vol. 219,1 (2022). doi: https://doi.org/10.1084/jem.20202490
Ahmed N, Etzrodt M, Dettinger P, Kull T, Loeffler D, Hoppe PS, Chavez JS, Zhang Y, Camargo Ortega G, Hilsenbeck O, Nakajima H, Pietras EM, Schroeder T. Blood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulation. J Exp Med. 2022 Jan 03;219(1). doi: 10.1084/jem.20202490. Epub 2021 Nov 24. PMID: 34817548; PMCID: PMC8624737.
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Crown-Cut Endobronchial Ultrasound Guided Transbronchial Aspiration Needle: First Real-World Experiences.

Journal of clinical medicine

Oezkan F, Byun WY, Loeffler C, Siebolts U, Diessel L, Lambrecht N, Eisenmann S.
PMID: 35011904
J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010163.

Advancements in personalized medicine have increased the demand for quantity and preservation of tissue architecture of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) samples. These demands may be addressed by the SonoTip TopGain

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Oezkan F, Byun WY, Loeffler C, et al. Crown-Cut Endobronchial Ultrasound Guided Transbronchial Aspiration Needle: First Real-World Experiences. J Clin Med. 2021;11(1)doi: 10.3390/jcm11010163.
Oezkan, F., Byun, W. Y., Loeffler, C., Siebolts, U., Diessel, L., Lambrecht, N., & Eisenmann, S. (2021). Crown-Cut Endobronchial Ultrasound Guided Transbronchial Aspiration Needle: First Real-World Experiences. Journal of clinical medicine, 11(1), . https://doi.org/10.3390/jcm11010163
Oezkan, Filiz, et al. "Crown-Cut Endobronchial Ultrasound Guided Transbronchial Aspiration Needle: First Real-World Experiences." Journal of clinical medicine vol. 11,1 (2021). doi: https://doi.org/10.3390/jcm11010163
Oezkan F, Byun WY, Loeffler C, Siebolts U, Diessel L, Lambrecht N, Eisenmann S. Crown-Cut Endobronchial Ultrasound Guided Transbronchial Aspiration Needle: First Real-World Experiences. J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010163. PMID: 35011904.
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Avalanches and edge-of-chaos learning in neuromorphic nanowire networks.

Nature communications

Hochstetter J, Zhu R, Loeffler A, Diaz-Alvarez A, Nakayama T, Kuncic Z.
PMID: 34188085
Nat Commun. 2021 Jun 29;12(1):4008. doi: 10.1038/s41467-021-24260-z.

The brain's efficient information processing is enabled by the interplay between its neuro-synaptic elements and complex network structure. This work reports on the neuromorphic dynamics of nanowire networks (NWNs), a unique brain-inspired system with synapse-like memristive junctions embedded within...

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Hochstetter J, Zhu R, Loeffler A, et al. Avalanches and edge-of-chaos learning in neuromorphic nanowire networks. Nat Commun. 2021;12(1):4008doi: 10.1038/s41467-021-24260-z.
Hochstetter, J., Zhu, R., Loeffler, A., Diaz-Alvarez, A., Nakayama, T., & Kuncic, Z. (2021). Avalanches and edge-of-chaos learning in neuromorphic nanowire networks. Nature communications, 12(1), 4008. https://doi.org/10.1038/s41467-021-24260-z
Hochstetter, Joel, et al. "Avalanches and edge-of-chaos learning in neuromorphic nanowire networks." Nature communications vol. 12,1 (2021): 4008. doi: https://doi.org/10.1038/s41467-021-24260-z
Hochstetter J, Zhu R, Loeffler A, Diaz-Alvarez A, Nakayama T, Kuncic Z. Avalanches and edge-of-chaos learning in neuromorphic nanowire networks. Nat Commun. 2021 Jun 29;12(1):4008. doi: 10.1038/s41467-021-24260-z. PMID: 34188085; PMCID: PMC8242064.
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Homozygosity of BACHD rats not only causes strong behavioral deficits in young female rats but also a reduced breeding success.

Brain research

Kurat S, Heinrich P, Molnar-Kasza A, Loeffler T, Flunkert S, Hutter-Paier B.
PMID: 33662341
Brain Res. 2021 Mar 02;1761:147396. doi: 10.1016/j.brainres.2021.147396. Epub 2021 Mar 02.

Huntington's disease is known to be a purely genetic disease based on an expansion of a CAG base triplet repeat in the coding region of the Huntingtin gene. Some years ago, researchers were able to introduce the extensive full-length...

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Kurat S, Heinrich P, Molnar-Kasza A, et al. Homozygosity of BACHD rats not only causes strong behavioral deficits in young female rats but also a reduced breeding success. Brain Res. 2021;1761:147396doi: 10.1016/j.brainres.2021.147396.
Kurat, S., Heinrich, P., Molnar-Kasza, A., Loeffler, T., Flunkert, S., & Hutter-Paier, B. (2021). Homozygosity of BACHD rats not only causes strong behavioral deficits in young female rats but also a reduced breeding success. Brain research, 1761147396. https://doi.org/10.1016/j.brainres.2021.147396
Kurat, Stephan, et al. "Homozygosity of BACHD rats not only causes strong behavioral deficits in young female rats but also a reduced breeding success." Brain research vol. 1761 (2021): 147396. doi: https://doi.org/10.1016/j.brainres.2021.147396
Kurat S, Heinrich P, Molnar-Kasza A, Loeffler T, Flunkert S, Hutter-Paier B. Homozygosity of BACHD rats not only causes strong behavioral deficits in young female rats but also a reduced breeding success. Brain Res. 2021 Mar 02;1761:147396. doi: 10.1016/j.brainres.2021.147396. Epub 2021 Mar 02. PMID: 33662341.
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