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Showing 25 to 36 of 218 entries
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Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.

Brain : a journal of neurology

Liebmann M, Korn L, Janoschka C, Albrecht S, Lauks S, Herrmann AM, Schulte-Mecklenbeck A, Schwab N, Schneider-Hohendorf T, Eveslage M, Wildemann B, Luessi F, Schmidt S, Diebold M, Bittner S, Gross CC, Kovac S, Zipp F, Derfuss T, Kuhlmann T, König S, Meuth SG, Wiendl H, Klotz L.
PMID: 34849598
Brain. 2021 Nov 29;144(10):3126-3141. doi: 10.1093/brain/awab307.

Dimethyl fumarate, an approved treatment for relapsing-remitting multiple sclerosis, exerts pleiotropic effects on immune cells as well as CNS resident cells. Here, we show that dimethyl fumarate exerts a profound alteration of the metabolic profile of human CD4+ as...

Loss of CASK Accelerates Heart Failure Development.

Circulation research

Mustroph J, Sag CM, Bähr F, Schmidtmann AL, Gupta SN, Dietz A, Islam MMT, Lücht C, Beuthner BE, Pabel S, Baier MJ, El-Armouche A, Sossalla S, Anderson ME, Möllmann J, Lehrke M, Marx N, Mohler PJ, Bers DM, Unsöld B, He T, Dewenter M, Backs J, Maier LS, Wagner S.
PMID: 33593074
Circ Res. 2021 Apr 16;128(8):1139-1155. doi: 10.1161/CIRCRESAHA.120.318170. Epub 2021 Feb 17.

[Figure: see text].

Bifacial Color-Tunable Electroluminescent Devices.

ACS applied materials & interfaces

Gahlmann T, Tschorn T, Maschwitz T, Gomell L, Haeger T, Grötsch G, Heiderhoff R, Riedl T.
PMID: 34111924
ACS Appl Mater Interfaces. 2021 Jun 23;13(24):28514-28520. doi: 10.1021/acsami.1c08360. Epub 2021 Jun 10.

Alternate current electroluminescent (ACEL) devices provide a range of interesting properties, such as facile large-area processability, mechanical flexibility, and outstanding resilience, when compared with other large-area light-emitting technologies. To widen the scope of possible applications for ACEL devices, color...

Cytosolic CTP Production Limits the Establishment of Photosynthesis in .

Frontiers in plant science

Bellin L, Scherer V, Dörfer E, Lau A, Vicente AM, Meurer J, Hickl D, Möhlmann T.
PMID: 34917117
Front Plant Sci. 2021 Nov 30;12:789189. doi: 10.3389/fpls.2021.789189. eCollection 2021.

CTP synthases (CTPS) comprise a protein family of the five members CTPS1-CTPS5 in Arabidopsis, all located in the cytosol. Specifically, downregulation of

Do equilibrium and rate constants of intramicellar reactions depend on micelle size?.

Physical chemistry chemical physics : PCCP

Kohlmann T, Goez M.
PMID: 33908509
Phys Chem Chem Phys. 2021 Apr 28;23(16):9709-9714. doi: 10.1039/d1cp00400j.

We have studied the combined static and dynamic quenching of pyrene by methyl viologen in sodium alkyl sulfate micelles varying in volume by a factor of more than 4. Size controls were the temperature T (283 K-333 K) and...

Ranking the Harm of Psychoactive Drugs Including Prescription Analgesics to Users and Others-A Perspective of German Addiction Medicine Experts.

Frontiers in psychiatry

Bonnet U, Specka M, Soyka M, Alberti T, Bender S, Grigoleit T, Hermle L, Hilger J, Hillemacher T, Kuhlmann T, Kuhn J, Luckhaus C, Lüdecke C, Reimer J, Schneider U, Schroeder W, Stuppe M, Wiesbeck GA, Wodarz N, McAnally H, Scherbaum N.
PMID: 33192740
Front Psychiatry. 2020 Oct 26;11:592199. doi: 10.3389/fpsyt.2020.592199. eCollection 2020.

No abstract available.

Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury.

Journal of the American Society of Nephrology : JASN

Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Möllmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, März W, Reiser J, Jankowski J, Fliser D, Speer T, Jankowski V.
PMID: 34588185
J Am Soc Nephrol. 2021 Sep 29; doi: 10.1681/ASN.2021040503. Epub 2021 Sep 29.

BACKGROUND: Coexistent CKD and cardiovascular diseases are highly prevalent in Western populations and account for substantial mortality. We recently found that apolipoprotein C-3 (ApoC3), a major constituent of triglyceride-rich lipoproteins, induces sterile systemic inflammation by activating the NOD-like receptor...

Species Identity, Life History, and Geographic Distance Influence Gut Bacterial Communities in Lab-Reared and European Field-Collected Culicoides Biting midges.

Microbial ecology

Möhlmann TWR, Ter Braak CJF, Te Beest DE, Hendriks M, Nijhuis EH, Warris S, Drolet BS, van Overbeek L, Koenraadt CJM.
PMID: 34436640
Microb Ecol. 2021 Aug 26; doi: 10.1007/s00248-021-01822-8. Epub 2021 Aug 26.

Bacteria are part of the insect gut system and influence many physiological traits of their host. Gut bacteria may even reduce or block the transmission of arboviruses in several species of arthropod vectors. Culicoides biting midges are important arboviral...

Brain functional correlates of emotional face processing in body dysmorphic disorder.

Journal of psychiatric research

Borgers T, Kürten M, Kappelhoff A, Enneking V, Möllmann A, Schulte J, Klug M, Leehr EJ, Dohm K, Grotegerd D, Krause P, Zwiky E, Dannlowski U, Buhlmann U, Redlich R.
PMID: 35030511
J Psychiatr Res. 2022 Jan 07;147:103-110. doi: 10.1016/j.jpsychires.2022.01.007. Epub 2022 Jan 07.

Previous neuroimaging studies in body dysmorphic disorder (BDD) have focused on discordances in visual processing systems. However, little is known about brain functional aberrations in individuals with BDD during emotional face processing. An fMRI paradigm with negative emotional faces...

Neural mapping of anhedonia across psychiatric diagnoses: A transdiagnostic neuroimaging analysis.

NeuroImage. Clinical

Schaub AC, Kirschner M, Schweinfurth N, Mählmann L, Kettelhack C, Engeli EE, Doll JPK, Borgwardt S, Lang UE, Kaiser S, Walter M, Herdener M, Wrege J, Schmidt A.
PMID: 34544030
Neuroimage Clin. 2021;32:102825. doi: 10.1016/j.nicl.2021.102825. Epub 2021 Sep 16.

Anhedonia has been associated with abnormal reward-related striatal dopamine functioning in patients with different psychiatric disorders. Here, we tested whether anhedonia expression mapped onto striatal volume across several psychiatric diagnoses. T1-weighted images from 313 participants including 89 healthy controls...

Hydrofilm Polyurethane Films Reduce Radiation Dermatitis Severity in Hypofractionated Whole-Breast Irradiation: An Objective, Intra-Patient Randomized Dual-Center Assessment.

Polymers

Schmeel LC, Koch D, Schmeel FC, Bücheler B, Leitzen C, Mahlmann B, Kunze D, Heimann M, Brüser D, Abramian AV, Schoroth F, Müdder T, Röhner F, Garbe S, Baumert BG, Schild HH, Wilhelm-Buchstab TM.
PMID: 31888185
Polymers (Basel). 2019 Dec 16;11(12). doi: 10.3390/polym11122112.

Radiation-induced skin injury represents the most frequent side effect in breast cancer patients undergoing whole-breast irradiation (WBI). Numerous clinical studies on systemic and topical treatments for radiation dermatitis have failed to provide sustainable treatment strategies. While protective skin products...

One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2.

Stem cell reports

Chanoumidou K, Hernández-Rodríguez B, Windener F, Thomas C, Stehling M, Mozafari S, Albrecht S, Ottoboni L, Antel J, Kim KP, Velychko S, Cui QL, Xu YKT, Martino G, Winkler J, Schöler HR, Baron-Van Evercooren A, Boespflug-Tanguy O, Vaquerizas JM, Ehrlich M, Kuhlmann T.
PMID: 33770499
Stem Cell Reports. 2021 Apr 13;16(4):771-783. doi: 10.1016/j.stemcr.2021.03.001. Epub 2021 Mar 25.

Limited access to human oligodendrocytes impairs better understanding of oligodendrocyte pathology in myelin diseases. Here, we describe a method to robustly convert human fibroblasts directly into oligodendrocyte-like cells (dc-hiOLs), which allows evaluation of remyelination-promoting compounds and disease modeling. Ectopic...

Showing 25 to 36 of 218 entries