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Showing 2401 to 2406 of 2406 entries
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The Effect of Cyanine Dye NK-4 on Photoreceptor Degeneration in a Rat Model of Early-Stage Retinitis Pigmentosa.

Pharmaceuticals (Basel, Switzerland)

Liu S, Matsuo T, Miyaji M, Hosoya O.
PMID: 34358120
Pharmaceuticals (Basel). 2021 Jul 19;14(7). doi: 10.3390/ph14070694.

The present study aimed to evaluate the effects of NK-4 on the apoptosis of photoreceptors in a rat model of retinitis pigmentosa and explore the mechanism underlying anti-apoptosis activity. The Royal College of Surgeons (RCS) rats received an intravitreous...

Mortality associated with nonrestorative short sleep or nonrestorative long time-in-bed in middle-aged and older adults.

Scientific reports

Yoshiike T, Utsumi T, Matsui K, Nagao K, Saitoh K, Otsuki R, Aritake-Okada S, Suzuki M, Kuriyama K.
PMID: 34997027
Sci Rep. 2022 Jan 07;12(1):189. doi: 10.1038/s41598-021-03997-z.

Associations of sleep duration with human health could differ depending on whether sleep is restorative. Using data from 5804 participants of the Sleep Heart Health Study, we examined the longitudinal association of sleep restfulness combined with polysomnography-measured total sleep...

Impact of pre-treatment C-reactive protein level and skeletal muscle mass on outcomes after stereotactic body radiotherapy for T1N0M0 non-small cell lung cancer: a supplementary analysis of the Japan Clinical Oncology Group study JCOG0403.

Journal of radiation research

Matsuo Y, Nagata Y, Wakabayashi M, Ishikura S, Onishi H, Kokubo M, Karasawa K, Shioyama Y, Onimaru R, Hiraoka M.
PMID: 34350956
J Radiat Res. 2021 Sep 13;62(5):901-909. doi: 10.1093/jrr/rrab065.

This study aimed to evaluate the impact of pretreatment C-reactive protein (CRP) and skeletal muscle mass (SMM) on outcomes after stereotactic body radiotherapy (SBRT) for T1N0M0 non-small cell lung cancer (NSCLC) as a supplementary analysis of JCOG0403. Patients were...

Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair Induced by Glucocorticoids in Mice.

International journal of molecular sciences

Okada K, Kawao N, Nakai D, Wakabayashi R, Horiuchi Y, Okumoto K, Kurashimo S, Takafuji Y, Matsuo O, Kaji H.
PMID: 35008904
Int J Mol Sci. 2022 Jan 01;23(1). doi: 10.3390/ijms23010478.

Glucocorticoids delay fracture healing and induce osteoporosis. However, the mechanisms by which glucocorticoids delay bone repair have yet to be clarified. Plasminogen activator inhibitor-1 (PAI-1) is the principal inhibitor of plasminogen activators and an adipocytokine that regulates metabolism. We...

Identification of ksg1 mutation showing long-lived phenotype in fission yeast.

Genes to cells : devoted to molecular & cellular mechanisms

Matsui K, Okamoto K, Hasegawa T, Ohtsuka H, Shimasaki T, Ihara K, Goto Y, Aoki K, Aiba H.
PMID: 34534388
Genes Cells. 2021 Dec;26(12):967-978. doi: 10.1111/gtc.12897. Epub 2021 Sep 26.

Fission yeast is a good model organism for the study of lifespan. To elucidate the mechanism, we screened for long-lived mutants. We found a nonsense mutation in the ksg1

Validity of Domain-Specific Sedentary Time Using Accelerometer and Questionnaire with activPAL Criterion.

International journal of environmental research and public health

So R, Matsuo T.
PMID: 34886498
Int J Environ Res Public Health. 2021 Dec 03;18(23). doi: 10.3390/ijerph182312774.

Accelerometers based on the cut-point method are generally the most used in sedentary time (ST) research. However, mixed cut-points are an issue, so an accelerometer based on metabolic equivalents (METs) could be used as an alternative. This study aimed...

Showing 2401 to 2406 of 2406 entries