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Showing 313 to 324 of 324 entries
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Synthesis and Evaluation of High Functionality and Quality Cell-penetrating Peptide Conjugated Lipid for Octaarginine Modified PEGylated Liposomes In U251 and U87 Glioma Cells.

Journal of pharmaceutical sciences

El-Gamal FR, Akl MA, Mowafy HA, Mukai H, Kawakami S, Afouna MI.
PMID: 34863974
J Pharm Sci. 2021 Dec 02; doi: 10.1016/j.xphs.2021.11.022. Epub 2021 Dec 02.

The use of peptide ligand modified PEGylated liposomes has been widely investigated for tumor targeting. Peptides are mainly inserted in the liposomal lipid bilayer using PEG

Nerve Hypertrophy and Altered Diffusion in Anti-Myelin-Associated Glycoprotein Neuropathy Detected by Brachial Plexus Magnetic Resonance Neurography.

European neurology

Koide K, Sugiyama A, Yokota H, Mukai H, Wang J, Nakamura K, Misawa S, Ito S, Kuwabara S.
PMID: 34583351
Eur Neurol. 2021 Sep 28;1-9. doi: 10.1159/000519128. Epub 2021 Sep 28.

INTRODUCTION: This study assessed the morphological changes and diffusion tensor imaging (DTI)-derived parameters of the brachial plexus using magnetic resonance neurography (MRN) in patients with anti-myelin-associated glycoprotein (anti-MAG) neuropathy.METHODS: Eight patients with anti-MAG neuropathy underwent MRN of the brachial...

Clinical and genetic analysis of children with hearing loss and bilateral enlarged vestibular aqueducts.

International journal of pediatric otorhinolaryngology

Nakano A, Arimoto Y, Mutai H, Nara K, Inoue S, Matsunaga T.
PMID: 34801268
Int J Pediatr Otorhinolaryngol. 2022 Jan;152:110975. doi: 10.1016/j.ijporl.2021.110975. Epub 2021 Nov 14.

OBJECTIVES: To evaluate the clinical and genetic features of children with hearing loss associated with one of the most common malformations of the inner ear: bilateral enlargement of vestibular aqueducts (EVA).METHODS: Clinical and genetic features were investigated in 28...

Hospital Pharmacy Preparedness and Pharmacist Role During Disaster in Saudi Arabia.

Risk management and healthcare policy

Aljabri A, Bakhsh H, Baageel A, Al-Nimari S, Alshehri S, Bakadam B, Almasrahi S, Kutbi H.
PMID: 34955660
Risk Manag Healthc Policy. 2021 Dec 18;14:5039-5046. doi: 10.2147/RMHP.S343789. eCollection 2021.

BACKGROUND: In case of emergencies, the number and severity of mass casualties may exceed medical services resources. Saudi Arabia is prone to different disasters, and all medical resources should be ready and prepared to serve during disasters. Pharmacists are...

Assessing factors influencing pharmacy interns career choices in Saudi Arabia.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Bannan D, Alshibani M, Alshehri S, Aljabri A, Kutbi H.
PMID: 33603541
Saudi Pharm J. 2021 Jan;29(1):67-72. doi: 10.1016/j.jsps.2020.12.010. Epub 2020 Dec 22.

BACKGROUND: The number of students enrolled in the colleges of pharmacy in Saudi Arabia is high, and the number of pharmacy graduates expected to join the workforce in the coming years is expected to grow. There are limited number...

Nerve Hypertrophy and Altered Diffusion in Anti-Myelin-Associated Glycoprotein Neuropathy Detected by Brachial Plexus Magnetic Resonance Neurography.

European neurology

Koide K, Sugiyama A, Yokota H, Mukai H, Wang J, Nakamura K, Misawa S, Ito S, Kuwabara S.
PMID: 34583351
Eur Neurol. 2021 Sep 28;1-9. doi: 10.1159/000519128. Epub 2021 Sep 28.

INTRODUCTION: This study assessed the morphological changes and diffusion tensor imaging (DTI)-derived parameters of the brachial plexus using magnetic resonance neurography (MRN) in patients with anti-myelin-associated glycoprotein (anti-MAG) neuropathy.METHODS: Eight patients with anti-MAG neuropathy underwent MRN of the brachial...

Protein Kinase N Family Negatively Regulates Constitutive Androstane Receptor-Mediated Transcriptional Induction of Cytochrome P450 2b10 in the Livers of Mice.

The Journal of pharmacology and experimental therapeutics

Kawase A, Mukai H, Tateishi S, Kuroda S, Kazaoka A, Satoh R, Shimada H, Sugiura R, Iwaki M.
PMID: 34312179
J Pharmacol Exp Ther. 2021 Oct;379(1):53-63. doi: 10.1124/jpet.121.000790. Epub 2021 Jul 26.

In receptor-type transcription factors-mediated cytochrome P450 (P450) induction, few studies have attempted to clarify the roles of protein kinase N (PKN) in the transcriptional regulation of P450s. This study aimed to examine the involvement of PKN in the transcriptional...

Assessing the Feasibility of Adapting a School-Based HIV Prevention Intervention to Include Voluntary Male Medical Circumcision and Vaccination for Human Papilloma Virus Prevention.

The East African health research journal

Barbara B, Joseph O, Mevis O, Mutai K.
PMID: 34308227
East Afr Health Res J. 2020;4(1):108-112. doi: 10.24248/eahrj.v4i1.628. Epub 2020 Jun 26.

In 2012, there were 2,454 cases and 1,676 deaths from cervical cancer in Kenya. Human Papilloma Virus (HPV) is responsible for 99% of all cervical cancers. National cervical cancer prevention guidelines recommend HPV vaccination among HPV-naïve pre-adolescent girls' prior...

Surgically treated gastric cancer in Japan: 2011 annual report of the national clinical database gastric cancer registry.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Suzuki S, Takahashi A, Ishikawa T, Akazawa K, Katai H, Isobe Y, Miyashiro I, Ono H, Tanabe S, Fukagawa T, Muro K, Nunobe S, Kadowaki S, Suzuki H, Irino T, Usune S, Miyata H, Kakeji Y.
PMID: 33811588
Gastric Cancer. 2021 May;24(3):545-566. doi: 10.1007/s10120-021-01178-5. Epub 2021 Apr 03.

BACKGROUND: The National Clinical Database (NCD) nationwide registry program of gastric cancer started in 2018. The purpose of this study was to report the treatment results of the NCD registry in the form of treatment results of the real...

Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study.

PloS one

Tanabe H, Mutai H, Sasayama D, Sasamoto H, Miyashiro Y, Sugiyama N, Washizuka S.
PMID: 34910781
PLoS One. 2021 Dec 15;16(12):e0261440. doi: 10.1371/journal.pone.0261440. eCollection 2021.

Animal experiments have consistently shown that estrogen receptor β (ERβ)-selective ligands have antidepressant and anxiolytic effects. In humans, endogenous ligands for ERβ include 5α-androstane-3β, 17β-diol (3βAdiol) and androstenediol (Δ5-diol). We determined, for the first time, the exact serum levels...

A global metagenomic map of urban microbiomes and antimicrobial resistance.

Cell

Danko D, Bezdan D, Afshin EE, Ahsanuddin S, Bhattacharya C, Butler DJ, Chng KR, Donnellan D, Hecht J, Jackson K, Kuchin K, Karasikov M, Lyons A, Mak L, Meleshko D, Mustafa H, Mutai B, Neches RY, Ng A, Nikolayeva O, Nikolayeva T, Png E, Ryon KA, Sanchez JL, Shaaban H, Sierra MA, Thomas D, Young B, Abudayyeh OO, Alicea J, Bhattacharyya M, Blekhman R, Castro-Nallar E, Cañas AM, Chatziefthimiou AD, Crawford RW, De Filippis F, Deng Y, Desnues C, Dias-Neto E, Dybwad M, Elhaik E, Ercolini D, Frolova A, Gankin D, Gootenberg JS, Graf AB, Green DC, Hajirasouliha I, Hastings JJA, Hernandez M, Iraola G, Jang S, Kahles A, Kelly FJ, Knights K, Kyrpides NC, Łabaj PP, Lee PKH, Leung MHY, Ljungdahl PO, Mason-Buck G, McGrath K, Meydan C, Mongodin EF, Moraes MO, Nagarajan N, Nieto-Caballero M, Noushmehr H, Oliveira M, Ossowski S, Osuolale OO, Özcan O, Paez-Espino D, Rascovan N, Richard H, Rätsch G, Schriml LM, Semmler T, Sezerman OU, Shi L, Shi T, Siam R, Song LH, Suzuki H, Court DS, Tighe SW, Tong X, Udekwu KI, Ugalde JA, Valentine B, Vassilev DI, Vayndorf EM, Velavan TP, Wu J, Zambrano MM, Zhu J, Zhu S, Mason CE.
PMID: 34043940
Cell. 2021 Jun 24;184(13):3376-3393.e17. doi: 10.1016/j.cell.2021.05.002. Epub 2021 May 26.

We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains,...

Three-Year Rates of Reoperation and Revision Following Mobile Versus Fixed-Bearing Total Ankle Arthroplasty: A Cohort of 302 Patients with 2 Implants of Similar Design.

The Journal of bone and joint surgery. American volume

Assal M, Kutaish H, Acker A, Hattendorf J, Lübbeke A, Crevoisier X.
PMID: 34424866
J Bone Joint Surg Am. 2021 Nov 17;103(22):2080-2088. doi: 10.2106/JBJS.20.02172.

BACKGROUND: Currently, the implants utilized in total ankle arthroplasty (TAA) are divided between mobile-bearing 3-component and fixed-bearing 2-component designs. The literature evaluating the influence of this mobility difference on implant survival is sparse. The purpose of the present study...

Showing 313 to 324 of 324 entries