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Showing 13 to 24 of 795 entries
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Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

Oncotarget

Borst GR, Kumareswaran R, Yücel H, Telli S, Do T, McKee T, Zafarana G, Jonkers J, Verheij M, O'Connor MJ, Rottenberg S, Bristow RG.
PMID: 29152107
Oncotarget. 2017 Sep 15;8(50):87638-87646. doi: 10.18632/oncotarget.20936. eCollection 2017 Oct 20.

Clinical trials are studying the benefits of combining the PARP-1 inhibitor olaparib with chemotherapy and radiotherapy treatment in a variety of cancer increasing the therapeutic ratio for olaparib may come from its ability to modify the tumour microenvironment by...

Managing the potential and pitfalls during clinical translation of emerging stem cell therapies.

Clinical and translational medicine

Main H, Munsie M, O'Connor MD.
PMID: 24949190
Clin Transl Med. 2014 May 09;3:10. doi: 10.1186/2001-1326-3-10. eCollection 2014.

We are moving into a new era of stem cell research where many possibilities for treatment of degenerative, chronic and/or fatal diseases and injuries are becoming primed for clinical trial. These reports have led millions of people worldwide to...

Extranodal rosai-dorfman disease of the bone treated with surgery and radiotherapy.

Rare tumors

Paryani NN, Daugherty LC, O'Connor MI, Jiang L.
PMID: 25568748
Rare Tumors. 2014 Dec 11;6(4):5531. doi: 10.4081/rt.2014.5531. eCollection 2014 Oct 27.

Rosai-Dorfman disease (RDD) is a rare, benign histiocyte disorder originally described by Rosai and Dorfman in 1969 as sinus histiocytosis with massive lymphadenopathy. It most typically presents as massive, painless cervical lymphadenopathy, and it is most often found in...

Bayesian Analysis of Blood Transfusion in Dracula.

Irish medical journal

O'Connor M, Dunbar N.
PMID: 27685695
Ir Med J. 2016 Feb 19;109(2):362.

No abstract available.

Predictive Factors for the Development of Type 2 Endoleak Following Endovascular Aneurysm Repair.

Seminars in interventional radiology

O'Connor PJ, Lookstein RA.
PMID: 26327746
Semin Intervent Radiol. 2015 Sep;32(3):272-7. doi: 10.1055/s-0035-1558466.

Type 2 endoleak (T2EL) is the most common complication following endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms. The management of T2ELs is controversial due to the relatively low incidence of negative outcomes when secondary intervention is avoided. Some...

Pelvic Insufficiency Fractures.

Geriatric orthopaedic surgery & rehabilitation

O'Connor TJ, Cole PA.
PMID: 26246940
Geriatr Orthop Surg Rehabil. 2014 Dec;5(4):178-90. doi: 10.1177/2151458514548895.

Pelvic insufficiency fractures may occur in the absence of trauma or as a result of low-energy trauma in osteoporotic bone. With a growing geriatric population, the incidence of pelvic insufficiency fracture has increased over the last 3 decades and...

Development of measures assessing attitudes toward contraband tobacco among a web-based sample of smokers.

Tobacco induced diseases

Adkison SE, O'Connor RJ, Chaiton M, Schwartz R.
PMID: 25914612
Tob Induc Dis. 2015 Mar 27;13(1):7. doi: 10.1186/s12971-015-0032-0. eCollection 2015.

BACKGROUND: As regulation of tobacco products tightens, there are concerns that illicit markets may develop to supply restricted products. However, there are few validated measures to assess attitudes or purchase intentions toward contraband tobacco (CT). As such, it is...

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Neoplasms: Systemic Therapy - Biotherapy and Novel Targeted Agents.

Neuroendocrinology

Pavel M, Valle JW, Eriksson B, Rinke A, Caplin M, Chen J, Costa F, Falkerby J, Fazio N, Gorbounova V, de Herder W, Kulke M, Lombard-Bohas C, O'Connor J, Sorbye H, Garcia-Carbonero R.
PMID: 28351033
Neuroendocrinology. 2017;105(3):266-280. doi: 10.1159/000471880. Epub 2017 Mar 29.

No abstract available.

Measuring mental health literacy--a review of scale-based measures.

Journal of mental health (Abingdon, England)

O'Connor M, Casey L, Clough B.
PMID: 24785120
J Ment Health. 2014 Aug;23(4):197-204. doi: 10.3109/09638237.2014.910646. Epub 2014 Apr 30.

BACKGROUND: Mental Health Literacy (MHL) has become an important concept in the literature; however, quantitative research on MHL methodology has been limited.AIMS: This review identified peer-reviewed papers investigating MHL, assessed psychometric attributes of scale-based measures of MHL, and the...

Synthesis and Characterization of Novel Oxo-Bridged Dinuclear and Hydroxo-Bridged Trinuclear Chromium(III) Assemblies.

Inorganic chemistry

Harton A, Terrell K, Huffman JC, MacDonald C, Beatty A, Li S, O'Connor CJ, Vincent JB.
PMID: 11670168
Inorg Chem. 1997 Oct 08;36(21):4875-4882. doi: 10.1021/ic961247t.

The structural and spectroscopic properties of a novel dinuclear chromium-oxo and a trinuclear chromium-hydroxo complex are reported. The dinuclear assembly, [Cr(2)(&mgr;-O)(2)(&mgr;-O(2)CMe)(bpy)(2)(H(2)O)(2)]ClO(4).bpy.[bpyH]ClO(4) (1), crystallizes in the monoclinic space group Cc with a = 16.8259(8) Å, b = 21.9622(11) Å, c...

A Multistep Topotactic Route to the New Mixed-Valence Titanate, Na(2)(-)(x)()(+)(y)()Ca(x)()(/2)La(2)Ti(3)O(10). Electron Localization Effects in a Triple-Layered Perovskite.

Inorganic chemistry

Lalena JN, Cushing BL, Falster AU, Simmons WB, Seip CT, Carpenter EE, O'Connor CJ, Wiley JB.
PMID: 11670590
Inorg Chem. 1998 Sep 07;37(18):4484-4485. doi: 10.1021/ic980611g.

No abstract available.

An experimental and computational study of 1,2-hydrogen migrations in 2-hydroxycyclopentylidene and its conjugate base.

The Journal of organic chemistry

Morgan KM, O'Connor MJ, Humphrey JL, Buschman KE.
PMID: 11262102
J Org Chem. 2001 Mar 09;66(5):1600-6. doi: 10.1021/jo001038x.

Thermal decomposition of alpha-hydroxydiazirine 2 gives primarily cyclopentanone and some allylic alcohol, in similar amounts as the known cyclohexyl analogue 1. Calculations (B3LYP/6-31+G) also show cyclopentanone to be the major product of this carbene rearrangement. Diazirine 2 and the...

Showing 13 to 24 of 795 entries