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Showing 13 to 24 of 367 entries
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Anti-metastatic effects of viral and non-viral mediated Nk4 delivery to tumours.

Genetic vaccines and therapy

Buhles A, Collins SA, van Pijkeren JP, Rajendran S, Miles M, O'Sullivan GC, O'Hanlon DM, Tangney M.
PMID: 19272140
Genet Vaccines Ther. 2009 Mar 09;7:5. doi: 10.1186/1479-0556-7-5.

The most common cause of death of cancer sufferers is through the occurrence of metastases. The metastatic behaviour of tumour cells is regulated by extracellular growth factors such as hepatocyte growth factor (HGF), a ligand for the c-Met receptor...

Characteristics of extreme ultraviolet emission from mid-infrared laser-produced rare-earth Gd plasmas.

Optics express

Higashiguchi T, Li B, Suzuki Y, Kawasaki M, Ohashi H, Torii S, Nakamura D, Takahashi A, Okada T, Jiang W, Miura T, Endo A, Dunne P, O'Sullivan G, Makimura T.
PMID: 24514779
Opt Express. 2013 Dec 30;21(26):31837-45. doi: 10.1364/OE.21.031837.

We characterize extreme ultraviolet (EUV) emission from mid-infrared (mid-IR) laser-produced plasmas (LPPs) of the rare-earth element Gd. The energy conversion efficiency (CE) and the spectral purity in the mid-IR LPPs at λL = 10.6 μm were higher than for...

The effects of blood pressure on rebleeding when using ExcelArrest™ in a porcine model of lethal femoral injury.

Journal of emergencies, trauma, and shock

Hirst H, Brinkman J, Beasley A, Crocker R, O'Sullivan J.
PMID: 21769207
J Emerg Trauma Shock. 2011 Apr;4(2):207-11. doi: 10.4103/0974-2700.82207.

BACKGROUND: Uncontrolled hemorrhage is one of the leading causes of death in both combat and civilian trauma. This study was designed to compare the arterial blood pressures at which rebleeding occurred when a hemostatic agent, ExcelArrest™, was used compared...

Beyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid Tumors.

Frontiers in oncology

O'Sullivan CC, Moon DH, Kohn EC, Lee JM.
PMID: 24616882
Front Oncol. 2014 Feb 28;4:42. doi: 10.3389/fonc.2014.00042. eCollection 2014.

Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown clinical activity in patients with germline BRCA1/2 mutation (gBRCAm)-associated breast and ovarian cancers. Accumulating evidence suggests that PARPi may have a wider application in the treatment of cancers defective in DNA damage repair...

Selection of target elements for laser-produced plasma soft x-ray sources.

Optics letters

Tamura T, Arai G, Kondo Y, Hara H, Hatano T, Ejima T, Jiang W, Suzuki C, O'Sullivan G, Higashiguchi T.
PMID: 29714741
Opt Lett. 2018 May 01;43(9):2042-2045. doi: 10.1364/OL.43.002042.

We demonstrated the upper limitation to the number of shots, i.e., target lifetime, together with the number of photons emitted in the water-window soft x-ray spectral region from a number of targets used as sources in this spectral region,...

Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.

Cell reports

Hinson JT, Chopra A, Lowe A, Sheng CC, Gupta RM, Kuppusamy R, O'Sullivan J, Rowe G, Wakimoto H, Gorham J, Burke MA, Zhang K, Musunuru K, Gerszten RE, Wu SM, Chen CS, Seidman JG, Seidman CE.
PMID: 28614725
Cell Rep. 2017 Jun 13;19(11):2410. doi: 10.1016/j.celrep.2017.05.038.

No abstract available.

Aortic Dissection: Novel Surgical Hybrid Procedures.

Interventional cardiology (London, England)

Cannavale A, Santoni M, Fanelli F, O'Sullivan G.
PMID: 29588732
Interv Cardiol. 2017 May;12(1):56-60. doi: 10.15420/icr.2016:16:3.

The management of patients with aortic dissection is challenging and its treatment is an area of development and innovation. Conventional surgical techniques are associated with significant risks in terms of mortality and morbidity in such high-risk patients. As a...

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

Molecular cell

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, de Vitis M, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ.
PMID: 32679078
Mol Cell. 2020 Jul 16;79(2):359. doi: 10.1016/j.molcel.2020.06.026.

No abstract available.

A core curriculum in the biological and biomedical sciences for dentistry.

European journal of dental education : official journal of the Association for Dental Education in Europe

Bennett JH, Beeley JA, Anderson P, Belfield L, Brand HS, Didilescu AC, Dymock D, Guven Y, Hector MP, Holbrook P, Jayasinghe JAP, O'Sullivan J, Riggio M, Roger-Leroi V, Scheven B, Sloan AJ, Vandamme K, Manzanares MC.
PMID: 32078216
Eur J Dent Educ. 2020 Aug;24(3):433-441. doi: 10.1111/eje.12518. Epub 2020 Mar 19.

INTRODUCTION: The biomedical sciences (BMS) are a central part of the dental curriculum that underpins teaching and clinical practice in all areas of dentistry. Although some specialist groups have proposed curricula in their particular topic areas, there is currently...

RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres.

Molecular cell

Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ.
PMID: 31585101
Mol Cell. 2019 Oct 03;76(1):217. doi: 10.1016/j.molcel.2019.08.009.

No abstract available.

Using next-generation sequencing to determine diversity of horse intestinal worms: identifying the equine 'nemabiome'.

Journal of equine science

Mitchell CJ, O'Sullivan CM, Pinloche E, Wilkinson T, Morphew RM, McEwan NR.
PMID: 30944540
J Equine Sci. 2019 Mar;30(1):1-5. doi: 10.1294/jes.30.1. Epub 2019 Apr 03.

Next-generation sequencing of DNA from nematode eggs has been utilised to give the first account of the equine 'nemabiome'. In all equine faecal samples investigated, multiple species of Strongylidae were detected, ranging from 7.5 (SEM 0.79) with 99+% identity...

Trends in 4d-subshell photoabsorption along the iodine isonuclear sequence: I, I+, and I2+.

Physical review. A, Atomic, molecular, and optical physics

Costello JT, Kennedy ET, McGuinness C, O'Sullivan G, Weinmann B.
PMID: 9913263
Phys Rev A. 1996 May;53(5):3211-3226. doi: 10.1103/physreva.53.3211.

No abstract available.

Showing 13 to 24 of 367 entries