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Showing 25 to 36 of 1537 entries
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Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors.

American journal of translational research

Kaira K, Nakamura K, Hirakawa T, Imai H, Tominaga H, Oriuchi N, Nagamori S, Kanai Y, Tsukamoto N, Oyama T, Asao T, Minegishi T.
PMID: 26279759
Am J Transl Res. 2015 Jun 15;7(6):1161-71. eCollection 2015.

AIM: Amino acid transporters are essential for the growth, progression and the pathogenesis of various cancers. However, it remains obscure about the clinicopathological significance of L-type amino acid transporter 1 (LAT1) and system ASC amino acid transporter 2 (ASCT2)...

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Kaira K, Nakamura K, Hirakawa T, et al. Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors. Am J Transl Res. 2015;7(6):1161-71
Kaira, K., Nakamura, K., Hirakawa, T., Imai, H., Tominaga, H., Oriuchi, N., Nagamori, S., Kanai, Y., Tsukamoto, N., Oyama, T., Asao, T., & Minegishi, T. (2015). Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors. American journal of translational research, 7(6), 1161-71.
Kaira, Kyoichi, et al. "Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors." American journal of translational research vol. 7,6 (2015): 1161-71.
Kaira K, Nakamura K, Hirakawa T, Imai H, Tominaga H, Oriuchi N, Nagamori S, Kanai Y, Tsukamoto N, Oyama T, Asao T, Minegishi T. Prognostic significance of L-type amino acid transporter 1 (LAT1) expression in patients with ovarian tumors. Am J Transl Res. 2015 Jun 15;7(6):1161-71. eCollection 2015. PMID: 26279759; PMCID: PMC4532748.
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Preeclampsia as a Manifestation of New-Onset Systemic Lupus Erythematosus during Pregnancy: A Case-Based Literature Review.

AJP reports

Miyamoto T, Hoshino T, Hayashi N, Oyama R, Okunomiya A, Kitamura S, Ohtake N, Suga M, Miyamoto K, Takaoka A, Aoki T, Imamura Y, Nagano S, Kita M.
PMID: 26929873
AJP Rep. 2016 Mar;6(1):e62-7. doi: 10.1055/s-0035-1566245. Epub 2015 Nov 03.

Introduction New-onset systemic lupus erythematosus (SLE) during pregnancy is rare and difficult to diagnose, especially in cases that manifest as preeclampsia. We report a patient with new-onset SLE that manifested as preeclampsia during pregnancy and provide a review of...

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Miyamoto T, Hoshino T, Hayashi N, et al. Preeclampsia as a Manifestation of New-Onset Systemic Lupus Erythematosus during Pregnancy: A Case-Based Literature Review. AJP Rep. 2015;6(1):e62-7doi: 10.1055/s-0035-1566245.
Miyamoto, T., Hoshino, T., Hayashi, N., Oyama, R., Okunomiya, A., Kitamura, S., Ohtake, N., Suga, M., Miyamoto, K., Takaoka, A., Aoki, T., Imamura, Y., Nagano, S., & Kita, M. (2016). Preeclampsia as a Manifestation of New-Onset Systemic Lupus Erythematosus during Pregnancy: A Case-Based Literature Review. AJP reports, 6(1), e62-7. https://doi.org/10.1055/s-0035-1566245
Miyamoto, Taito, et al. "Preeclampsia as a Manifestation of New-Onset Systemic Lupus Erythematosus during Pregnancy: A Case-Based Literature Review." AJP reports vol. 6,1 (2016): e62-7. doi: https://doi.org/10.1055/s-0035-1566245
Miyamoto T, Hoshino T, Hayashi N, Oyama R, Okunomiya A, Kitamura S, Ohtake N, Suga M, Miyamoto K, Takaoka A, Aoki T, Imamura Y, Nagano S, Kita M. Preeclampsia as a Manifestation of New-Onset Systemic Lupus Erythematosus during Pregnancy: A Case-Based Literature Review. AJP Rep. 2016 Mar;6(1):e62-7. doi: 10.1055/s-0035-1566245. Epub 2015 Nov 03. PMID: 26929873; PMCID: PMC4737630.
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Two Additional Acute Nonlymphocytic Leukemia Patients with a Sole Chromosome Abnormality of Trisomy 4.

Leukemia & lymphoma

Tauchi T, Ohyashiki K, Kodama A, Iwabuchi A, Ohyashiki JH, Toyama K.
PMID: 27456580
Leuk Lymphoma. 1990;2(1):131-5. doi: 10.3109/10428199009042523.

We report two cases of acute nonlymphocytic leukemia (ANLL) in which the circulating leukemic cells showed trisomy of chromosome 4 as the sole cytogenetic abnormality. Trisomy 4 is rarely found in hematopoietic neoplasia and until now the few reported...

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Tauchi T, Ohyashiki K, Kodama A, et al. Two Additional Acute Nonlymphocytic Leukemia Patients with a Sole Chromosome Abnormality of Trisomy 4. Leuk Lymphoma. 1990;2(1):131-5doi: 10.3109/10428199009042523.
Tauchi, T., Ohyashiki, K., Kodama, A., Iwabuchi, A., Ohyashiki, J. H., & Toyama, K. (1990). Two Additional Acute Nonlymphocytic Leukemia Patients with a Sole Chromosome Abnormality of Trisomy 4. Leukemia & lymphoma, 2(1), 131-5. https://doi.org/10.3109/10428199009042523
Tauchi, T, et al. "Two Additional Acute Nonlymphocytic Leukemia Patients with a Sole Chromosome Abnormality of Trisomy 4." Leukemia & lymphoma vol. 2,1 (1990): 131-5. doi: https://doi.org/10.3109/10428199009042523
Tauchi T, Ohyashiki K, Kodama A, Iwabuchi A, Ohyashiki JH, Toyama K. Two Additional Acute Nonlymphocytic Leukemia Patients with a Sole Chromosome Abnormality of Trisomy 4. Leuk Lymphoma. 1990;2(1):131-5. doi: 10.3109/10428199009042523. PMID: 27456580.
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Purification and Characterization of Arctium lappa L. (Edible Burdock) Polyphenol Oxidase.

Bioscience, biotechnology, and biochemistry

Murao S, Oyama H, Nomura Y, Tono T, Shin T.
PMID: 27314765
Biosci Biotechnol Biochem. 1993 Jan;57(2):177-80. doi: 10.1271/bbb.57.177.

Polyphenol oxidase of Arctium lappa L. (edible burdock) has been purified by chromatographies on DEAE-cellulose, Sephadex G-75, and phenyl-Cellulofine to a homogeneous state as judged by SDS polyacrylamide gel electrophoresis. The molecular weight of the purified enzyme was estimated...

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Murao S, Oyama H, Nomura Y, et al. Purification and Characterization of Arctium lappa L. (Edible Burdock) Polyphenol Oxidase. Biosci Biotechnol Biochem. 1993;57(2):177-80doi: 10.1271/bbb.57.177.
Murao, S., Oyama, H., Nomura, Y., Tono, T., & Shin, T. (1993). Purification and Characterization of Arctium lappa L. (Edible Burdock) Polyphenol Oxidase. Bioscience, biotechnology, and biochemistry, 57(2), 177-80. https://doi.org/10.1271/bbb.57.177
Murao, S, et al. "Purification and Characterization of Arctium lappa L. (Edible Burdock) Polyphenol Oxidase." Bioscience, biotechnology, and biochemistry vol. 57,2 (1993): 177-80. doi: https://doi.org/10.1271/bbb.57.177
Murao S, Oyama H, Nomura Y, Tono T, Shin T. Purification and Characterization of Arctium lappa L. (Edible Burdock) Polyphenol Oxidase. Biosci Biotechnol Biochem. 1993 Jan;57(2):177-80. doi: 10.1271/bbb.57.177. PMID: 27314765.
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Efficient terahertz detection in a sheet cavity using a nonlinear optical parametric process.

Applied optics

Saito K, Tanabe T, Oyama Y.
PMID: 26192850
Appl Opt. 2015 Jun 10;54(17):5475-80. doi: 10.1364/AO.54.005475.

We designed and simulated a GaP-based sheet cavity structure for room-temperature THz wave detection via a nonlinear optical (NLO) parametric process, using photonic conversion from THz frequencies to the optical domain. The sheet cavity structure consisted of a GaP...

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Saito K, Tanabe T, Oyama Y. Efficient terahertz detection in a sheet cavity using a nonlinear optical parametric process. Appl Opt. 2015;54(17):5475-80doi: 10.1364/AO.54.005475.
Saito, K., Tanabe, T., & Oyama, Y. (2015). Efficient terahertz detection in a sheet cavity using a nonlinear optical parametric process. Applied optics, 54(17), 5475-80. https://doi.org/10.1364/AO.54.005475
Saito, Kyosuke, et al. "Efficient terahertz detection in a sheet cavity using a nonlinear optical parametric process." Applied optics vol. 54,17 (2015): 5475-80. doi: https://doi.org/10.1364/AO.54.005475
Saito K, Tanabe T, Oyama Y. Efficient terahertz detection in a sheet cavity using a nonlinear optical parametric process. Appl Opt. 2015 Jun 10;54(17):5475-80. doi: 10.1364/AO.54.005475. PMID: 26192850.
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Effects of rabeprazole on bone metabolic disorders in a gastrectomized rat model.

Biomedical reports

Yamasaki Y, Fujimura T, Oyama K, Higashi Y, Hirose A, Tsukada T, Okamoto K, Kinoshita J, Nakamura K, Miyashita T, Tajima H, Takamura H, Ninomiya I, Fushida S, Ohta T.
PMID: 27330752
Biomed Rep. 2016 Jul;5(1):118-124. doi: 10.3892/br.2016.689. Epub 2016 May 23.

Proton pump inhibitors (PPIs) are frequently prescribed to patients with gastroesophageal reflux disease; however, the number of bone fractures reportedly increased in these patients. Although PPIs have been shown to inhibit the bone resorption by osteoclasts, the effect of...

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Yamasaki Y, Fujimura T, Oyama K, et al. Effects of rabeprazole on bone metabolic disorders in a gastrectomized rat model. Biomed Rep. 2016;5(1):118-124doi: 10.3892/br.2016.689.
Yamasaki, Y., Fujimura, T., Oyama, K., Higashi, Y., Hirose, A., Tsukada, T., Okamoto, K., Kinoshita, J., Nakamura, K., Miyashita, T., Tajima, H., Takamura, H., Ninomiya, I., Fushida, S., & Ohta, T. (2016). Effects of rabeprazole on bone metabolic disorders in a gastrectomized rat model. Biomedical reports, 5(1), 118-124. https://doi.org/10.3892/br.2016.689
Yamasaki, Yuki, et al. "Effects of rabeprazole on bone metabolic disorders in a gastrectomized rat model." Biomedical reports vol. 5,1 (2016): 118-124. doi: https://doi.org/10.3892/br.2016.689
Yamasaki Y, Fujimura T, Oyama K, Higashi Y, Hirose A, Tsukada T, Okamoto K, Kinoshita J, Nakamura K, Miyashita T, Tajima H, Takamura H, Ninomiya I, Fushida S, Ohta T. Effects of rabeprazole on bone metabolic disorders in a gastrectomized rat model. Biomed Rep. 2016 Jul;5(1):118-124. doi: 10.3892/br.2016.689. Epub 2016 May 23. PMID: 27330752; PMCID: PMC4906904.
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Design of a GaP/Si composite waveguide for CW terahertz wave generation via difference frequency mixing.

Applied optics

Saito K, Tanabe T, Oyama Y.
PMID: 24921119
Appl Opt. 2014 Jun 10;53(17):3587-92. doi: 10.1364/AO.53.003587.

We design a GaP/Si composite waveguide to achieve efficient terahertz (THz) wave generation under collinear phase-matched difference frequency mixing (DFM) between near-infrared light sources. This waveguide structure provides a strong mode confinement of both near-infrared sources and THz wave,...

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Saito K, Tanabe T, Oyama Y. Design of a GaP/Si composite waveguide for CW terahertz wave generation via difference frequency mixing. Appl Opt. 2014;53(17):3587-92doi: 10.1364/AO.53.003587.
Saito, K., Tanabe, T., & Oyama, Y. (2014). Design of a GaP/Si composite waveguide for CW terahertz wave generation via difference frequency mixing. Applied optics, 53(17), 3587-92. https://doi.org/10.1364/AO.53.003587
Saito, Kyosuke, et al. "Design of a GaP/Si composite waveguide for CW terahertz wave generation via difference frequency mixing." Applied optics vol. 53,17 (2014): 3587-92. doi: https://doi.org/10.1364/AO.53.003587
Saito K, Tanabe T, Oyama Y. Design of a GaP/Si composite waveguide for CW terahertz wave generation via difference frequency mixing. Appl Opt. 2014 Jun 10;53(17):3587-92. doi: 10.1364/AO.53.003587. PMID: 24921119.
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Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer.

American journal of translational research

Kaira K, Arakawa K, Shimizu K, Oriuchi N, Nagamori S, Kanai Y, Oyama T, Takeyoshi I.
PMID: 25901202
Am J Transl Res. 2015 Feb 15;7(2):356-63. eCollection 2015.

CD147 functions as an induction of matrix metalloproteinases and tumor angiogenesis, and is highly expressed in various malignant neoplasms. Recently, CD147 is shown to form a complex with amino acid transporters such as L-type amino acid transporter (LAT1), system...

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Kaira K, Arakawa K, Shimizu K, et al. Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer. Am J Transl Res. 2015;7(2):356-63
Kaira, K., Arakawa, K., Shimizu, K., Oriuchi, N., Nagamori, S., Kanai, Y., Oyama, T., & Takeyoshi, I. (2015). Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer. American journal of translational research, 7(2), 356-63.
Kaira, Kyoichi, et al. "Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer." American journal of translational research vol. 7,2 (2015): 356-63.
Kaira K, Arakawa K, Shimizu K, Oriuchi N, Nagamori S, Kanai Y, Oyama T, Takeyoshi I. Relationship between CD147 and expression of amino acid transporters (LAT1 and ASCT2) in patients with pancreatic cancer. Am J Transl Res. 2015 Feb 15;7(2):356-63. eCollection 2015. PMID: 25901202; PMCID: PMC4399098.
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Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer.

OncoTargets and therapy

Fushida S, Kaji M, Oyama K, Hirono Y, Nezuka H, Takeda T, Tsukada T, Fujimoto D, Ohyama S, Fujimura T, Ohta T.
PMID: 25960665
Onco Targets Ther. 2015 Apr 23;8:939-41. doi: 10.2147/OTT.S83114. eCollection 2015.

The standard regimen of second-line chemotherapy for patients with unresectable gastric cancer has not been established. However, weekly paclitaxel (wPTX) has become the preferable second-line chemotherapy in Japan. Histone deacetylase (HDAC) inhibitors have been shown to have antiproliferative activity...

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Fushida S, Kaji M, Oyama K, et al. Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer. Onco Targets Ther. 2015;8:939-41doi: 10.2147/OTT.S83114.
Fushida, S., Kaji, M., Oyama, K., Hirono, Y., Nezuka, H., Takeda, T., Tsukada, T., Fujimoto, D., Ohyama, S., Fujimura, T., & Ohta, T. (2015). Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer. OncoTargets and therapy, 8939-41. https://doi.org/10.2147/OTT.S83114
Fushida, Sachio, et al. "Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer." OncoTargets and therapy vol. 8 (2015): 939-41. doi: https://doi.org/10.2147/OTT.S83114
Fushida S, Kaji M, Oyama K, Hirono Y, Nezuka H, Takeda T, Tsukada T, Fujimoto D, Ohyama S, Fujimura T, Ohta T. Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer. Onco Targets Ther. 2015 Apr 23;8:939-41. doi: 10.2147/OTT.S83114. eCollection 2015. PMID: 25960665; PMCID: PMC4410891.
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Small ion-temperature-gradient scale length and reduced heat diffusivity at large hydrogen isotope mass in conventional H-mode plasmas.

Physical review letters

Urano H, Takizuka T, Kikuchi M, Nakano T, Hayashi N, Oyama N, Kamada Y.
PMID: 23005950
Phys Rev Lett. 2012 Sep 21;109(12):125001. doi: 10.1103/PhysRevLett.109.125001. Epub 2012 Sep 18.

The dependence of the ion-temperature-gradient scale length on the hydrogen isotope mass was examined in conventional H-mode plasmas in JT-60U tokamak. While identical profiles for density and temperature were obtained for hydrogen and deuterium plasmas, the ion conductive heat...

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Urano H, Takizuka T, Kikuchi M, et al. Small ion-temperature-gradient scale length and reduced heat diffusivity at large hydrogen isotope mass in conventional H-mode plasmas. Phys Rev Lett. 2012;109(12):125001doi: 10.1103/PhysRevLett.109.125001.
Urano, H., Takizuka, T., Kikuchi, M., Nakano, T., Hayashi, N., Oyama, N., & Kamada, Y. (2012). Small ion-temperature-gradient scale length and reduced heat diffusivity at large hydrogen isotope mass in conventional H-mode plasmas. Physical review letters, 109(12), 125001. https://doi.org/10.1103/PhysRevLett.109.125001
Urano, H, et al. "Small ion-temperature-gradient scale length and reduced heat diffusivity at large hydrogen isotope mass in conventional H-mode plasmas." Physical review letters vol. 109,12 (2012): 125001. doi: https://doi.org/10.1103/PhysRevLett.109.125001
Urano H, Takizuka T, Kikuchi M, Nakano T, Hayashi N, Oyama N, Kamada Y. Small ion-temperature-gradient scale length and reduced heat diffusivity at large hydrogen isotope mass in conventional H-mode plasmas. Phys Rev Lett. 2012 Sep 21;109(12):125001. doi: 10.1103/PhysRevLett.109.125001. Epub 2012 Sep 18. PMID: 23005950.
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Impact of histone deacetylase 1 and metastasis-associated gene 1 expression in esophageal carcinogenesis.

Oncology letters

Miyashita T, Tajima H, Munemoto M, Shah FA, Harmon JW, Watanabe T, Shoji M, Okamoto K, Nakanuma S, Sakai S, Kinoshita J, Makino I, Nakamura K, Hayashi H, Oyama K, Inokuchi M, Nakagawara H, Takamura H, Ninomiya I, Kitagawa H, Fushida S, Mukaisho K, Fujimura T, Ohta T.
PMID: 25009653
Oncol Lett. 2014 Aug;8(2):758-764. doi: 10.3892/ol.2014.2176. Epub 2014 May 26.

Animal models are important for the development of novel therapies for esophageal cancer. Histone deacetylase 1 (

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Miyashita T, Tajima H, Munemoto M, et al. Impact of histone deacetylase 1 and metastasis-associated gene 1 expression in esophageal carcinogenesis. Oncol Lett. 2014;8(2):758-764doi: 10.3892/ol.2014.2176.
Miyashita, T., Tajima, H., Munemoto, M., Shah, F. A., Harmon, J. W., Watanabe, T., Shoji, M., Okamoto, K., Nakanuma, S., Sakai, S., Kinoshita, J., Makino, I., Nakamura, K., Hayashi, H., Oyama, K., Inokuchi, M., Nakagawara, H., Takamura, H., Ninomiya, I., Kitagawa, H., Fushida, S., Mukaisho, K., Fujimura, T., & Ohta, T. (2014). Impact of histone deacetylase 1 and metastasis-associated gene 1 expression in esophageal carcinogenesis. Oncology letters, 8(2), 758-764. https://doi.org/10.3892/ol.2014.2176
Miyashita, Tomoharu, et al. "Impact of histone deacetylase 1 and metastasis-associated gene 1 expression in esophageal carcinogenesis." Oncology letters vol. 8,2 (2014): 758-764. doi: https://doi.org/10.3892/ol.2014.2176
Miyashita T, Tajima H, Munemoto M, Shah FA, Harmon JW, Watanabe T, Shoji M, Okamoto K, Nakanuma S, Sakai S, Kinoshita J, Makino I, Nakamura K, Hayashi H, Oyama K, Inokuchi M, Nakagawara H, Takamura H, Ninomiya I, Kitagawa H, Fushida S, Mukaisho K, Fujimura T, Ohta T. Impact of histone deacetylase 1 and metastasis-associated gene 1 expression in esophageal carcinogenesis. Oncol Lett. 2014 Aug;8(2):758-764. doi: 10.3892/ol.2014.2176. Epub 2014 May 26. PMID: 25009653; PMCID: PMC4081431.
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Conservation of the pure adiabatic state in Ehrenfest dynamics of the photoisomerization of molecules.

Scientific reports

Miyamoto Y, Tateyama Y, Oyama N, Ohno T.
PMID: 26658633
Sci Rep. 2015 Dec 11;5:18220. doi: 10.1038/srep18220.

We examined real-time-propagation time-dependent density functional theory (rtp-TDDFT) coupled with molecular dynamics (MD), which uses single-particle representation of time-evolving wavefunctions allowing exchange of orbital characteristics between occupied and empty states making the effective Kohn-Sham Hamiltonian dependent on the potential...

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Miyamoto Y, Tateyama Y, Oyama N, et al. Conservation of the pure adiabatic state in Ehrenfest dynamics of the photoisomerization of molecules. Sci Rep. 2015;5:18220doi: 10.1038/srep18220.
Miyamoto, Y., Tateyama, Y., Oyama, N., & Ohno, T. (2015). Conservation of the pure adiabatic state in Ehrenfest dynamics of the photoisomerization of molecules. Scientific reports, 518220. https://doi.org/10.1038/srep18220
Miyamoto, Yoshiyuki, et al. "Conservation of the pure adiabatic state in Ehrenfest dynamics of the photoisomerization of molecules." Scientific reports vol. 5 (2015): 18220. doi: https://doi.org/10.1038/srep18220
Miyamoto Y, Tateyama Y, Oyama N, Ohno T. Conservation of the pure adiabatic state in Ehrenfest dynamics of the photoisomerization of molecules. Sci Rep. 2015 Dec 11;5:18220. doi: 10.1038/srep18220. PMID: 26658633; PMCID: PMC4676005.
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