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Showing 25 to 36 of 213 entries
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Tracking external introductions of HIV using phylodynamics reveals a major source of infections in rural KwaZulu-Natal, South Africa.

Virus evolution

Rasmussen DA, Wilkinson E, Vandormael A, Tanser F, Pillay D, Stadler T, de Oliveira T.
PMID: 30555720
Virus Evol. 2018 Dec 11;4(2):vey037. doi: 10.1093/ve/vey037. eCollection 2018 Jul.

Despite increasing access to antiretrovirals, HIV incidence in rural KwaZulu-Natal remains among the highest ever reported in Africa. While many epidemiological factors have been invoked to explain such high incidence, widespread human mobility and viral movement suggest that transmission...

HIV treatment is associated with a two-fold higher probability of raised triglycerides: Pooled Analyses in 21 023 individuals in sub-Saharan Africa.

Global health, epidemiology and genomics

Ekoru K, Young EH, Dillon DG, Gurdasani D, Stehouwer N, Faurholt-Jepsen D, Levitt NS, Crowther NJ, Nyirenda M, Njelekela MA, Ramaiya K, Nyan O, Adewole OO, Anastos K, Compostella C, Dave JA, Fourie CM, Friis H, Kruger IM, Longenecker CT, Maher DP, Mutimura E, Ndhlovu CE, Praygod G, Pefura Yone EW, Pujades-Rodriguez M, Range N, Sani MU, Sanusi M, Schutte AE, Sliwa K, Tien PC, Vorster EH, Walsh C, Gareta D, Mashili F, Sobngwi E, Adebamowo C, Kamali A, Seeley J, Smeeth L, Pillay D, Motala AA, Kaleebu P, Sandhu MS.
PMID: 29881632
Glob Health Epidemiol Genom. 2018;3. doi: 10.1017/gheg.2018.7. Epub 2018 May 08.

BACKGROUND: Anti-retroviral therapy (ART) regimes for HIV are associated with raised levels of circulating triglycerides (TG) in western populations. However, there are limited data on the impact of ART on cardiometabolic risk in sub-Saharan African (SSA) populations.METHODS: Pooled analyses...

Antiretroviral therapy based HIV prevention targeting young women who sell sex: a mixed method approach to understand the implementation of PrEP in a rural area of KwaZulu-Natal, South Africa.

AIDS care

Chimbindi N, Mthiyane N, Zuma T, Baisley K, Pillay D, McGrath N, Harling G, Sherr L, Birdthistle I, Floyd S, Dreyer J, Nakasone S, Seeley J, Shahmanesh M.
PMID: 33769156
AIDS Care. 2021 Mar 26;1-9. doi: 10.1080/09540121.2021.1902933. Epub 2021 Mar 26.

Pre-Exposure Prophylaxis (PrEP) is a potential game-changer for HIV. We used PrEP introduction for Young Women Who Sell Sex (YWSS) in a rural South Africa district to understand community norms and PrEP coverage in YWSS. Between 2017 and 2018,...

Should rural Latin America align to the international diabetes rise forecasts?.

Diabetes research and clinical practice

Pillay TD, Bernabe-Ortiz A, Málaga G, Miranda JJ.
PMID: 22410394
Diabetes Res Clin Pract. 2012 Jul;97(1):e1-2. doi: 10.1016/j.diabres.2012.02.003. Epub 2012 Mar 10.

No abstract available.

Influence of cholesterol on cancer progression and therapy.

Translational oncology

Mayengbam SS, Singh A, Pillai AD, Bhat MK.
PMID: 33751965
Transl Oncol. 2021 Jun;14(6):101043. doi: 10.1016/j.tranon.2021.101043. Epub 2021 Mar 20.

Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and is vital to various normal biological functions. It is a key factor in lifestyle-related diseases including obesity, diabetes, cardiovascular disease, and cancer. Owing to its altered...

Factors associated with paediatric and adolescent Emergency Department presentations involving acute behavioural disturbance events.

Journal of paediatrics and child health

Lovett CJ, Hiles JA, Calver L, Pallas JD, Thomson Bowe K, Downes MA.
PMID: 34375471
J Paediatr Child Health. 2021 Aug 10; doi: 10.1111/jpc.15668. Epub 2021 Aug 10.

AIM: Studies reporting factors associated with paediatric/adolescent acute behavioural disturbance (ABD) in the Emergency Department (ED) are lacking. The aim of this study is to describe paediatric/adolescent ED presentations involving ABD events.METHODS: A retrospective chart review of presentations involving...

Pitfalls of Single Measurement Screening for Diabetes and Hypertension in Community-Based Settings.

Global heart

Olivier S, Murray T, Matthews P, Mhlongo N, Gunda R, Baisley K, Gareta D, Modise T, Smit T, Herbst K, Mpofana X, Ndung'u T, Koole O, Pillay D, Hanekom W, Wong E, Siedner MJ.
PMID: 34900570
Glob Heart. 2021 Dec 03;16(1):79. doi: 10.5334/gh.1083. eCollection 2021.

BACKGROUND: Cross-sectional screening programs are used to detect and refer individuals with non-communicable diseases to healthcare services. We evaluated the positive predictive value of cross-sectional measurements for Diabetes Mellitus (DM) and hypertension (HTN) as part of a community-based disease...

Cohort Profile: The Vukuzazi ('Wake Up and Know Yourself' in isiZulu) population science programme.

International journal of epidemiology

Gunda R, Koole O, Gareta D, Olivier S, Surujdeen A, Smit T, Modise T, Dreyer J, Ording-Jespersen G, Munatsi D, Nxumalo S, Khoza T, Mhlongo N, Baisley K, Seeley J, Grant AD, Herbst K, Ndung'u T, Hanekom WA, Siedner MJ, Pillay D, Wong EB.
PMID: 34849923
Int J Epidemiol. 2021 Nov 29; doi: 10.1093/ije/dyab229. Epub 2021 Nov 29.

No abstract available.

Broncho-tracheal Compression Caused by Oesophageal Impaction After Bilateral Lung Transplantation.

American journal of respiratory and critical care medicine

Zoethout AC, Erasmus ME, Verschuuren E, Pillay J.
PMID: 34767498
Am J Respir Crit Care Med. 2021 Nov 12; doi: 10.1164/rccm.202105-1253IM. Epub 2021 Nov 12.

No abstract available.

Damsel in distress calling on her knights: Illuminating the pioneering role of E3 ubiquitin ligases in guarding the genome integrity.

DNA repair

Sahay O, Barik GK, Sharma T, Pillai AD, Rapole S, Santra MK.
PMID: 34920250
DNA Repair (Amst). 2022 Jan;109:103261. doi: 10.1016/j.dnarep.2021.103261. Epub 2021 Dec 10.

The maintenance of genomic integrity is of utmost importance for the organisms to survive and to accurately inherit traits to their progenies. Any kind of DNA damage either due to defect in DNA duplication and/ or uncontrolled cell division...

Gold nanoparticles show electroactivity: counting and sorting nanoparticles upon impact with electrodes.

Chemical communications (Cambridge, England)

Zhou YG, Rees NV, Pillay J, Tshikhudo R, Vilakazi S, Compton RG.
PMID: 22086114
Chem Commun (Camb). 2012 Jan 07;48(2):224-6. doi: 10.1039/c1cc16407d. Epub 2011 Nov 16.

Gold nanoparticles (AuNPs) in aqueous 0.10 M HCl are shown to be electroactive at oxidising potentials greater than 1.0 V (vs. Ag/AgCl) by means of voltammetric monitoring of AuNP-electrode collisions. The method promises the use of anodic particle coulometry...

Making Narrative Statements to Describe Treatment Effects.

Journal of general internal medicine

Murad MH, Fiordalisi C, Pillay J, Wilt TJ, O'Connor E, Kahwati L, Hernandez AV, Rutter CM, Chou R, Balk EM, Steele DW, Saldanha IJ, Panagiotou OA, Chang S, Gerrity M.
PMID: 33111244
J Gen Intern Med. 2021 Jan;36(1):196-199. doi: 10.1007/s11606-020-06330-y. Epub 2020 Oct 27.

Accurately describing treatment effects using plain language and narrative statements is a critical step in communicating research findings to end users. However, the process of developing these narratives has not been historically guided by a specific framework. The Agency...

Showing 25 to 36 of 213 entries