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Showing 25 to 36 of 38 entries
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Analysis of Phthalates and Alternative Plasticizers in Gloves by Gas Chromatography-Mass Spectrometry and Liquid Chromatography-UV Detection: A Comparative Study.

Toxics

Poitou K, Rogez-Florent T, Lecoeur M, Danel C, Regnault R, Vérité P, Monteil C, Foulon C.
PMID: 34564351
Toxics. 2021 Aug 28;9(9). doi: 10.3390/toxics9090200.

Gloves represent an essential feature for hand protection because it is a requirement in the professional framework to comply with both hand hygiene standards and the principles of good laboratory practice. Despite their wide use, there is a knowledge...

Time Mating Guinea Pigs by Monitoring Changes to the Vaginal Membrane throughout the Estrus Cycle and with Ultrasound Confirmation.

Methods and protocols

Wilson RL, Lampe K, Matushewski BJ, Regnault TRH, Jones HN.
PMID: 34564304
Methods Protoc. 2021 Aug 27;4(3). doi: 10.3390/mps4030058.

One of the greatest challenges to the development and implementation of pregnancy therapeutics is the ability to rigorously test treatments in clinically relevant animal models. Guinea pigs offer a unique advantage in studying the placenta, fetal development, and reproductive...

Gestational age impacts birth to placental weight ratio and umbilical cord oxygen values with implications for the fetal oxygen margin of safety.

Early human development

Richardson BS, de Vrijer B, Brown HK, Stitt L, Choo S, Regnault TRH.
PMID: 34839188
Early Hum Dev. 2022 Jan;164:105511. doi: 10.1016/j.earlhumdev.2021.105511. Epub 2021 Nov 20.

BACKGROUND: We determined the impact of gestational age (GA) from near term to term to post-term on birth/placental weight ratio and cord oxygen values with implications for placental transport efficiency for oxygen, fetal OMATERIALS AND METHODS: A hospital database...

Sex-specific alterations in hepatic cholesterol metabolism in low birth weight adult guinea pigs.

Pediatric research

Sarr O, Mathers KE, Vanderboor C, Wiggers K, Devgan A, Hardy DB, Zhao L, Regnault TRH.
PMID: 34230622
Pediatr Res. 2021 Jul 06; doi: 10.1038/s41390-021-01491-w. Epub 2021 Jul 06.

BACKGROUND: Intrauterine growth restriction and low birth weight (LBW) have been widely reported as an independent risk factor for adult hypercholesterolaemia and increased hepatic cholesterol in a sex-specific manner. However, the specific impact of uteroplacental insufficiency (UPI), a leading...

Seeing the fetus from a DOHaD perspective: discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress.

Journal of developmental origins of health and disease

Morrison JL, Ayonrinde OT, Care AS, Clarke GD, Darby JRT, David AL, Dean JM, Hooper SB, Kitchen MJ, Macgowan CK, Melbourne A, McGillick EV, McKenzie CA, Michael N, Mohammed N, Sadananthan SA, Schrauben E, Regnault TRH, Velan SS.
PMID: 32955011
J Dev Orig Health Dis. 2021 Apr;12(2):153-167. doi: 10.1017/S2040174420000884. Epub 2020 Sep 21.

Advanced imaging techniques are enhancing research capacity focussed on the developmental origins of adult health and disease (DOHaD) hypothesis, and consequently increasing awareness of future health risks across various subareas of DOHaD research themes. Understanding how these advanced imaging...

Impact of COVID-19 on the management of hepatocellular carcinoma in a high-prevalence area.

JHEP reports : innovation in hepatology

Amaddeo G, Brustia R, Allaire M, Lequoy M, Hollande C, Regnault H, Blaise L, Ganne-Carrié N, Séror O, Larrey E, Lim C, Scatton O, El Mouhadi S, Ozenne V, Paye F, Balladur P, Dohan A, Massault PP, Pol S, Dioguardi Burgio M, Vilgrain V, Sepulveda A, Cauchy F, Luciani A, Sommacale D, Leroy V, Roudot-Thoraval F, Bouattour M, Nault JC.
PMID: 33163949
JHEP Rep. 2021 Feb;3(1):100199. doi: 10.1016/j.jhepr.2020.100199. Epub 2020 Dec 22.

BACKGROUND & AIMS: Patients affected by hepatocellular carcinoma (HCC) represent a vulnerable population during the COVID-19 pandemic and may suffer from altered allocation of healthcare resources. The aim of this study was to determine the impact of the COVID-19...

Differential and Synergistic Effects of Low Birth Weight and Western Diet on Skeletal Muscle Vasculature, Mitochondrial Lipid Metabolism and Insulin Signaling in Male Guinea Pigs.

Nutrients

Dunlop K, Sarr O, Stachura N, Zhao L, Nygard K, Thompson JA, Hadway J, Richardson BS, Bureau Y, Borradaile N, Lee TY, Regnault TRH.
PMID: 34959870
Nutrients. 2021 Nov 29;13(12). doi: 10.3390/nu13124315.

Low birth weight (LBW) offspring are at increased risk for developing insulin resistance, a key precursor in metabolic syndrome and type 2 diabetes mellitus. Altered skeletal muscle vasculature, extracellular matrix, amino acid and mitochondrial lipid metabolism, and insulin signaling...

Evaluating the Effectiveness of Yttrium-90 Glass Microspheres in the Treatment of Hepatocellular Carcinoma, Intrahepatic Cholangiocarcinoma, and Metastatic Colorectal Cancer in Practice: Protocol for the Prospective PROACTIF Phase IV Registry Study in France.

Cardiovascular and interventional radiology

Garin E, Pinaquy JB, Bailly C, Sengel C, Mariano-Goulart D, Edeline J, Blanc JF, Bouvier A, Tordo J, Rode A, Becker S, Sefrioui D, de Baere T, Somma C, Mastier C, Goupil J, Chevallier P, Regnault H, Vibert E, Manfredi S, Vicaut E, Patel B, Boucher E, Guiu B.
PMID: 34796373
Cardiovasc Intervent Radiol. 2022 Jan;45(1):1-11. doi: 10.1007/s00270-021-03002-0. Epub 2021 Nov 18.

PRIMARY OBJECTIVE: Recently, selective internal radiation therapy using yttrium-90 (Y90) glass microspheres (TheraSphere™) was approved for reimbursement by health authorities in France. The PROACTIF study aims to gather data on effectiveness, patient quality of life, and safety with use...

Impact of birth weight and postnatal diet on the gut microbiota of young adult guinea pigs.

PeerJ

Al K, Sarr O, Dunlop K, Gloor GB, Reid G, Burton J, Regnault TR.
PMID: 28070463
PeerJ. 2017 Jan 03;5:e2840. doi: 10.7717/peerj.2840. eCollection 2017.

BACKGROUND: The gastrointestinal tract (GIT) microbiota is essential to metabolic health, and the prevalence of the Western diet (WD) high in fat and sugar is increasing, with evidence highlighting a negative interaction between the GIT and WD, resulting in...

Differential and Synergistic Effects of Low Birth Weight and Western Diet on Skeletal Muscle Vasculature, Mitochondrial Lipid Metabolism and Insulin Signaling in Male Guinea Pigs.

Nutrients

Dunlop K, Sarr O, Stachura N, Zhao L, Nygard K, Thompson JA, Hadway J, Richardson BS, Bureau Y, Borradaile N, Lee TY, Regnault TRH.
PMID: 34959870
Nutrients. 2021 Nov 29;13(12). doi: 10.3390/nu13124315.

Low birth weight (LBW) offspring are at increased risk for developing insulin resistance, a key precursor in metabolic syndrome and type 2 diabetes mellitus. Altered skeletal muscle vasculature, extracellular matrix, amino acid and mitochondrial lipid metabolism, and insulin signaling...

Gestational age impacts birth to placental weight ratio and umbilical cord oxygen values with implications for the fetal oxygen margin of safety.

Early human development

Richardson BS, de Vrijer B, Brown HK, Stitt L, Choo S, Regnault TRH.
PMID: 34839188
Early Hum Dev. 2021 Nov 20;164:105511. doi: 10.1016/j.earlhumdev.2021.105511. Epub 2021 Nov 20.

BACKGROUND: We determined the impact of gestational age (GA) from near term to term to post-term on birth/placental weight ratio and cord oxygen values with implications for placental transport efficiency for oxygen, fetal OMATERIALS AND METHODS: A hospital database...

Dimming the Powerhouse: Mitochondrial Dysfunction in the Liver and Skeletal Muscle of Intrauterine Growth Restricted Fetuses.

Frontiers in endocrinology

Pendleton AL, Wesolowski SR, Regnault TRH, Lynch RM, Limesand SW.
PMID: 34079518
Front Endocrinol (Lausanne). 2021 May 17;12:612888. doi: 10.3389/fendo.2021.612888. eCollection 2021.

Intrauterine growth restriction (IUGR) of the fetus, resulting from placental insufficiency (PI), is characterized by low fetal oxygen and nutrient concentrations that stunt growth rates of metabolic organs. Numerous animal models of IUGR recapitulate pathophysiological conditions found in human...

Showing 25 to 36 of 38 entries