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Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells.

Frontiers in pharmacology

Lee JY, Kuo CW, Tsai SL, Cheng SM, Chen SH, Chan HH, Lin CH, Lin KY, Li CF, Kanwar JR, Leung EY, Cheung CC, Huang WJ, Wang YC, Cheung CH.
PMID: 27065869
Front Pharmacol. 2016 Mar 31;7:81. doi: 10.3389/fphar.2016.00081. eCollection 2016.

SAHA is a class I HDAC/HDAC6 co-inhibitor and an autophagy inducer currently undergoing clinical investigations in breast cancer patients. However, the molecular mechanism of action of SAHA in breast cancer cells remains unclear. In this study, we found that...

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Lee JY, Kuo CW, Tsai SL, et al. Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Front Pharmacol. 2016;7:81doi: 10.3389/fphar.2016.00081.
Lee, J. Y., Kuo, C. W., Tsai, S. L., Cheng, S. M., Chen, S. H., Chan, H. H., Lin, C. H., Lin, K. Y., Li, C. F., Kanwar, J. R., Leung, E. Y., Cheung, C. C., Huang, W. J., Wang, Y. C., & Cheung, C. H. (2016). Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Frontiers in pharmacology, 781. https://doi.org/10.3389/fphar.2016.00081
Lee, Jane Ying-Chieh, et al. "Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells." Frontiers in pharmacology vol. 7 (2016): 81. doi: https://doi.org/10.3389/fphar.2016.00081
Lee JY, Kuo CW, Tsai SL, Cheng SM, Chen SH, Chan HH, Lin CH, Lin KY, Li CF, Kanwar JR, Leung EY, Cheung CC, Huang WJ, Wang YC, Cheung CH. Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Front Pharmacol. 2016 Mar 31;7:81. doi: 10.3389/fphar.2016.00081. eCollection 2016. PMID: 27065869; PMCID: PMC4814469.
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Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle.

Frontiers in aging neuroscience

Tsai SF, Chen PC, Calkins MJ, Wu SY, Kuo YM.
PMID: 27047373
Front Aging Neurosci. 2016 Mar 22;8:57. doi: 10.3389/fnagi.2016.00057. eCollection 2016.

Age-related cognitive impairment has become one of the most common health threats in many countries. The biological substrate of cognition is the interconnection of neurons to form complex information processing networks. Experience-based alterations in the activities of these information...

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Tsai SF, Chen PC, Calkins MJ, et al. Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle. Front Aging Neurosci. 2016;8:57doi: 10.3389/fnagi.2016.00057.
Tsai, S. F., Chen, P. C., Calkins, M. J., Wu, S. Y., & Kuo, Y. M. (2016). Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle. Frontiers in aging neuroscience, 857. https://doi.org/10.3389/fnagi.2016.00057
Tsai, Sheng-Feng, et al. "Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle." Frontiers in aging neuroscience vol. 8 (2016): 57. doi: https://doi.org/10.3389/fnagi.2016.00057
Tsai SF, Chen PC, Calkins MJ, Wu SY, Kuo YM. Exercise Counteracts Aging-Related Memory Impairment: A Potential Role for the Astrocytic Metabolic Shuttle. Front Aging Neurosci. 2016 Mar 22;8:57. doi: 10.3389/fnagi.2016.00057. eCollection 2016. PMID: 27047373; PMCID: PMC4801859.
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Omnidirectional Harvesting of Weak Light Using a Graphene Quantum Dot-Modified Organic/Silicon Hybrid Device.

ACS nano

Tsai ML, Tsai DS, Tang L, Chen LJ, Lau SP, He JH.
PMID: 28430415
ACS Nano. 2017 May 23;11(5):4564-4570. doi: 10.1021/acsnano.6b08567. Epub 2017 Apr 27.

Despite great improvements in traditional inorganic photodetectors and photovoltaics, more progress is needed in the detection/collection of light at low-level conditions. Traditional photodetectors tend to suffer from high noise when operated at room temperature; therefore, these devices require additional...

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Tsai ML, Tsai DS, Tang L, et al. Omnidirectional Harvesting of Weak Light Using a Graphene Quantum Dot-Modified Organic/Silicon Hybrid Device. ACS Nano. 2017;11(5):4564-4570doi: 10.1021/acsnano.6b08567.
Tsai, M. L., Tsai, D. S., Tang, L., Chen, L. J., Lau, S. P., & He, J. H. (2017). Omnidirectional Harvesting of Weak Light Using a Graphene Quantum Dot-Modified Organic/Silicon Hybrid Device. ACS nano, 11(5), 4564-4570. https://doi.org/10.1021/acsnano.6b08567
Tsai, Meng-Lin, et al. "Omnidirectional Harvesting of Weak Light Using a Graphene Quantum Dot-Modified Organic/Silicon Hybrid Device." ACS nano vol. 11,5 (2017): 4564-4570. doi: https://doi.org/10.1021/acsnano.6b08567
Tsai ML, Tsai DS, Tang L, Chen LJ, Lau SP, He JH. Omnidirectional Harvesting of Weak Light Using a Graphene Quantum Dot-Modified Organic/Silicon Hybrid Device. ACS Nano. 2017 May 23;11(5):4564-4570. doi: 10.1021/acsnano.6b08567. Epub 2017 Apr 27. PMID: 28430415.
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Earth Abundant Silicon Composites as the Electrocatalytic Counter Electrodes for Dye-Sensitized Solar Cells.

ACS applied materials & interfaces

Li CT, Tsai YL, Ho KC.
PMID: 26909565
ACS Appl Mater Interfaces. 2016 Mar 23;8(11):7037-46. doi: 10.1021/acsami.5b12423. Epub 2016 Mar 11.

UNLABELLED: Earth abundant silicon compounds, including Si3N4, SiO2, SiS2, and SiSe2, were introduced as the electrocatalytic materials for the counter electrodes (CE) in dye-sensitized solar cells (DSSCs). Among these silicon-based materials, Si3N4, SiS2, and SiSe2 were applied in DSSCs...

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Li CT, Tsai YL, Ho KC. Earth Abundant Silicon Composites as the Electrocatalytic Counter Electrodes for Dye-Sensitized Solar Cells. ACS Appl Mater Interfaces. 2016;8(11):7037-46doi: 10.1021/acsami.5b12423.
Li, C. T., Tsai, Y. L., & Ho, K. C. (2016). Earth Abundant Silicon Composites as the Electrocatalytic Counter Electrodes for Dye-Sensitized Solar Cells. ACS applied materials & interfaces, 8(11), 7037-46. https://doi.org/10.1021/acsami.5b12423
Li, Chun-Ting, et al. "Earth Abundant Silicon Composites as the Electrocatalytic Counter Electrodes for Dye-Sensitized Solar Cells." ACS applied materials & interfaces vol. 8,11 (2016): 7037-46. doi: https://doi.org/10.1021/acsami.5b12423
Li CT, Tsai YL, Ho KC. Earth Abundant Silicon Composites as the Electrocatalytic Counter Electrodes for Dye-Sensitized Solar Cells. ACS Appl Mater Interfaces. 2016 Mar 23;8(11):7037-46. doi: 10.1021/acsami.5b12423. Epub 2016 Mar 11. PMID: 26909565.
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CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core.

Organic letters

Chan CK, Tsai YL, Chang MY.
PMID: 28332839
Org Lett. 2017 Apr 07;19(7):1870-1873. doi: 10.1021/acs.orglett.7b00630. Epub 2017 Mar 23.

CuI/DMSO-mediated intramolecular cycloacetalization/ketalization of o-carbonyl allylbenzenes has been achieved for constructing [6,6,5]-tricycles having a ketal motif in good yields. The expeditious one-step route provides a three C-O bond formation. The key products with the structural framework of a benzofused...

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Chan CK, Tsai YL, Chang MY. CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core. Org Lett. 2017;19(7):1870-1873doi: 10.1021/acs.orglett.7b00630.
Chan, C. K., Tsai, Y. L., & Chang, M. Y. (2017). CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core. Organic letters, 19(7), 1870-1873. https://doi.org/10.1021/acs.orglett.7b00630
Chan, Chieh-Kai, et al. "CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core." Organic letters vol. 19,7 (2017): 1870-1873. doi: https://doi.org/10.1021/acs.orglett.7b00630
Chan CK, Tsai YL, Chang MY. CuI Mediated One-Pot Cycloacetalization/Ketalization of o-Carbonyl Allylbenzenes: Synthesis of Benzobicyclo[3.2.1]octane Core. Org Lett. 2017 Apr 07;19(7):1870-1873. doi: 10.1021/acs.orglett.7b00630. Epub 2017 Mar 23. PMID: 28332839.
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The Association of Aging with White Matter Integrity and Functional Connectivity Hubs.

Frontiers in aging neuroscience

Yang AC, Tsai SJ, Liu ME, Huang CC, Lin CP.
PMID: 27378915
Front Aging Neurosci. 2016 Jun 15;8:143. doi: 10.3389/fnagi.2016.00143. eCollection 2016.

Normal aging is associated with reduced cerebral structural integrity and altered functional brain activity, yet the association of aging with the relationship between structural and functional brain changes remains unclear. Using combined diffusion tensor imaging (DTI) and functional magnetic...

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Yang AC, Tsai SJ, Liu ME, et al. The Association of Aging with White Matter Integrity and Functional Connectivity Hubs. Front Aging Neurosci. 2016;8:143doi: 10.3389/fnagi.2016.00143.
Yang, A. C., Tsai, S. J., Liu, M. E., Huang, C. C., & Lin, C. P. (2016). The Association of Aging with White Matter Integrity and Functional Connectivity Hubs. Frontiers in aging neuroscience, 8143. https://doi.org/10.3389/fnagi.2016.00143
Yang, Albert C, et al. "The Association of Aging with White Matter Integrity and Functional Connectivity Hubs." Frontiers in aging neuroscience vol. 8 (2016): 143. doi: https://doi.org/10.3389/fnagi.2016.00143
Yang AC, Tsai SJ, Liu ME, Huang CC, Lin CP. The Association of Aging with White Matter Integrity and Functional Connectivity Hubs. Front Aging Neurosci. 2016 Jun 15;8:143. doi: 10.3389/fnagi.2016.00143. eCollection 2016. PMID: 27378915; PMCID: PMC4908139.
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Differential Response of Acidobacteria Subgroups to Forest-to-Pasture Conversion and Their Biogeographic Patterns in the Western Brazilian Amazon.

Frontiers in microbiology

Navarrete AA, Venturini AM, Meyer KM, Klein AM, Tiedje JM, Bohannan BJ, Nüsslein K, Tsai SM, Rodrigues JL.
PMID: 26733981
Front Microbiol. 2015 Dec 22;6:1443. doi: 10.3389/fmicb.2015.01443. eCollection 2015.

Members of the phylum Acidobacteria are among the most abundant soil bacteria on Earth, but little is known about their response to environmental changes. We asked how the relative abundance and biogeographic patterning of this phylum and its subgroups...

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Navarrete AA, Venturini AM, Meyer KM, et al. Differential Response of Acidobacteria Subgroups to Forest-to-Pasture Conversion and Their Biogeographic Patterns in the Western Brazilian Amazon. Front Microbiol. 2015;6:1443doi: 10.3389/fmicb.2015.01443.
Navarrete, A. A., Venturini, A. M., Meyer, K. M., Klein, A. M., Tiedje, J. M., Bohannan, B. J., Nüsslein, K., Tsai, S. M., & Rodrigues, J. L. (2015). Differential Response of Acidobacteria Subgroups to Forest-to-Pasture Conversion and Their Biogeographic Patterns in the Western Brazilian Amazon. Frontiers in microbiology, 61443. https://doi.org/10.3389/fmicb.2015.01443
Navarrete, Acacio A, et al. "Differential Response of Acidobacteria Subgroups to Forest-to-Pasture Conversion and Their Biogeographic Patterns in the Western Brazilian Amazon." Frontiers in microbiology vol. 6 (2015): 1443. doi: https://doi.org/10.3389/fmicb.2015.01443
Navarrete AA, Venturini AM, Meyer KM, Klein AM, Tiedje JM, Bohannan BJ, Nüsslein K, Tsai SM, Rodrigues JL. Differential Response of Acidobacteria Subgroups to Forest-to-Pasture Conversion and Their Biogeographic Patterns in the Western Brazilian Amazon. Front Microbiol. 2015 Dec 22;6:1443. doi: 10.3389/fmicb.2015.01443. eCollection 2015. PMID: 26733981; PMCID: PMC4686610.
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Comparison of electroacupuncture and morphine-mediated analgesic patterns in a plantar incision-induced pain model.

Evidence-based complementary and alternative medicine : eCAM

Zeng YJ, Tsai SY, Chen KB, Hsu SF, Chen JY, Wen YR.
PMID: 25530786
Evid Based Complement Alternat Med. 2014;2014:659343. doi: 10.1155/2014/659343. Epub 2014 Nov 02.

Electroacupuncture (EA) is a complementary therapy to improve morphine analgesia for postoperative pain, but underlying mechanism is not well-known. Herein, we investigated EA-induced analgesic effect in a plantar incision (PI) model in male Sprague-Dawley rats. PI was performed at...

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Zeng YJ, Tsai SY, Chen KB, et al. Comparison of electroacupuncture and morphine-mediated analgesic patterns in a plantar incision-induced pain model. Evid Based Complement Alternat Med. 2014;2014:659343doi: 10.1155/2014/659343.
Zeng, Y. J., Tsai, S. Y., Chen, K. B., Hsu, S. F., Chen, J. Y., & Wen, Y. R. (2014). Comparison of electroacupuncture and morphine-mediated analgesic patterns in a plantar incision-induced pain model. Evidence-based complementary and alternative medicine : eCAM, 2014659343. https://doi.org/10.1155/2014/659343
Zeng, Yen-Jing, et al. "Comparison of electroacupuncture and morphine-mediated analgesic patterns in a plantar incision-induced pain model." Evidence-based complementary and alternative medicine : eCAM vol. 2014 (2014): 659343. doi: https://doi.org/10.1155/2014/659343
Zeng YJ, Tsai SY, Chen KB, Hsu SF, Chen JY, Wen YR. Comparison of electroacupuncture and morphine-mediated analgesic patterns in a plantar incision-induced pain model. Evid Based Complement Alternat Med. 2014;2014:659343. doi: 10.1155/2014/659343. Epub 2014 Nov 02. PMID: 25530786; PMCID: PMC4233674.
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Enhanced electrical properties and field emission characteristics of AZO/ZnO-nanowire core-shell structures.

Physical chemistry chemical physics : PCCP

Huang JM, Tsai SY, Ku CS, Lin CM, Chen SY, Lee HY.
PMID: 27210896
Phys Chem Chem Phys. 2016 Jun 01;18(22):15251-9. doi: 10.1039/c6cp01011c.

The electrical properties and field-emission characteristics of ZnO nanowires (ZnO-NWs) fabricated using a vapor-liquid-solid method were systematically investigated. In particular, we explored the effects of Al-doped ZnO (AZO) films (thickness 4-100 nm) deposited on ZnO-NWs using an atomic layer...

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Huang JM, Tsai SY, Ku CS, et al. Enhanced electrical properties and field emission characteristics of AZO/ZnO-nanowire core-shell structures. Phys Chem Chem Phys. 2016;18(22):15251-9doi: 10.1039/c6cp01011c.
Huang, J. M., Tsai, S. Y., Ku, C. S., Lin, C. M., Chen, S. Y., & Lee, H. Y. (2016). Enhanced electrical properties and field emission characteristics of AZO/ZnO-nanowire core-shell structures. Physical chemistry chemical physics : PCCP, 18(22), 15251-9. https://doi.org/10.1039/c6cp01011c
Huang, Jheng-Ming, et al. "Enhanced electrical properties and field emission characteristics of AZO/ZnO-nanowire core-shell structures." Physical chemistry chemical physics : PCCP vol. 18,22 (2016): 15251-9. doi: https://doi.org/10.1039/c6cp01011c
Huang JM, Tsai SY, Ku CS, Lin CM, Chen SY, Lee HY. Enhanced electrical properties and field emission characteristics of AZO/ZnO-nanowire core-shell structures. Phys Chem Chem Phys. 2016 Jun 01;18(22):15251-9. doi: 10.1039/c6cp01011c. PMID: 27210896.
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Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs.

Chemistry (Weinheim an der Bergstrasse, Germany)

Hwu JR, Tsay SC, Chuang KS, Kapoor M, Lin JY, Yeh CS, Su WC, Wu PC, Tsai TL, Wang PW, Shieh DB.
PMID: 26752423
Chemistry. 2016 Feb;22(6):1926-1930. doi: 10.1002/chem.201504915. Epub 2016 Jan 11.

Platinum(II)-sulindac complexes [{η

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Hwu JR, Tsay SC, Chuang KS, et al. Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs. Chemistry. 2016;22(6):1926-1930doi: 10.1002/chem.201504915.
Hwu, J. R., Tsay, S. C., Chuang, K. S., Kapoor, M., Lin, J. Y., Yeh, C. S., Su, W. C., Wu, P. C., Tsai, T. L., Wang, P. W., & Shieh, D. B. (2016). Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs. Chemistry (Weinheim an der Bergstrasse, Germany), 22(6), 1926-1930. https://doi.org/10.1002/chem.201504915
Hwu, Jih Ru, et al. "Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 22,6 (2016): 1926-1930. doi: https://doi.org/10.1002/chem.201504915
Hwu JR, Tsay SC, Chuang KS, Kapoor M, Lin JY, Yeh CS, Su WC, Wu PC, Tsai TL, Wang PW, Shieh DB. Syntheses of Platinum-Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs. Chemistry. 2016 Feb;22(6):1926-1930. doi: 10.1002/chem.201504915. Epub 2016 Jan 11. PMID: 26752423.
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Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study.

OncoTargets and therapy

Lin KY, Cheng SM, Tsai SL, Tsai JY, Lin CH, Cheung CH.
PMID: 27217778
Onco Targets Ther. 2016 May 03;9:2601-13. doi: 10.2147/OTT.S101209. eCollection 2016.

Survivin is a member of the inhibitor-of-apoptosis proteins family. It is overexpressed in many different cancer types but not in the differentiated normal tissue. In addition, overexpression of survivin promotes cancer cell survival and induces chemotherapeutic drug resistance, making...

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Lin KY, Cheng SM, Tsai SL, et al. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016;9:2601-13doi: 10.2147/OTT.S101209.
Lin, K. Y., Cheng, S. M., Tsai, S. L., Tsai, J. Y., Lin, C. H., & Cheung, C. H. (2016). Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. OncoTargets and therapy, 92601-13. https://doi.org/10.2147/OTT.S101209
Lin, Kun-Yuan, et al. "Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study." OncoTargets and therapy vol. 9 (2016): 2601-13. doi: https://doi.org/10.2147/OTT.S101209
Lin KY, Cheng SM, Tsai SL, Tsai JY, Lin CH, Cheung CH. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016 May 03;9:2601-13. doi: 10.2147/OTT.S101209. eCollection 2016. PMID: 27217778; PMCID: PMC4862386.
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No association between an intronic presenilin-1 gene polymorphism and schizophrenia in a Chinese population.

Psychiatry research

Chiu HJ, Tsai SJ, Chen JY, Lin CY, Bai YM, Song HL, Lai HC, Hong CJ.
PMID: 10579558
Psychiatry Res. 1999 Oct 11;87(2):245-8. doi: 10.1016/s0165-1781(99)00066-9.

We investigated the association between schizophrenic psychosis and an intronic polymorphism of the presenilin-1 (PS1) gene in a Chinese population. Schizophrenic and control groups had similar PS1 genotype distributions and allele frequencies, indicating that this polymorphism may not be...

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Chiu HJ, Tsai SJ, Chen JY, et al. No association between an intronic presenilin-1 gene polymorphism and schizophrenia in a Chinese population. Psychiatry Res. 1999;87(2):245-8doi: 10.1016/s0165-1781(99)00066-9.
Chiu, H. J., Tsai, S. J., Chen, J. Y., Lin, C. Y., Bai, Y. M., Song, H. L., Lai, H. C., & Hong, C. J. (1999). No association between an intronic presenilin-1 gene polymorphism and schizophrenia in a Chinese population. Psychiatry research, 87(2), 245-8. https://doi.org/10.1016/s0165-1781(99)00066-9
Chiu, et al. "No association between an intronic presenilin-1 gene polymorphism and schizophrenia in a Chinese population." Psychiatry research vol. 87,2 (1999): 245-8. doi: https://doi.org/10.1016/s0165-1781(99)00066-9
Chiu HJ, Tsai SJ, Chen JY, Lin CY, Bai YM, Song HL, Lai HC, Hong CJ. No association between an intronic presenilin-1 gene polymorphism and schizophrenia in a Chinese population. Psychiatry Res. 1999 Oct 11;87(2):245-8. doi: 10.1016/s0165-1781(99)00066-9. PMID: 10579558.
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Showing 25 to 36 of 1545 entries