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Development of a predictive score for mortality at 3- and 12-month after discharge from an acute geriatric unit as a trigger for advanced care planning.

The journals of gerontology. Series A, Biological sciences and medical sciences

Deschasse G, Bloch F, Drumez E, Charpentier A, Visade F, Delecluse C, Loggia G, Lescure P, Attier-Żmudka J, Bloch J, Gaxatte C, Van Den Berghe W, Puisieux F, Beuscart JB.
PMID: 34375411
J Gerontol A Biol Sci Med Sci. 2021 Aug 10; doi: 10.1093/gerona/glab217. Epub 2021 Aug 10.

BACKGROUND: There is a need for a mortality score that can be used to trigger advanced care planning among older patients discharged from acute geriatric units (AGUs).OBJECTIVE: To develop a prognostic score for 3- and 12-month mortality after discharge...

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Deschasse G, Bloch F, Drumez E, et al. Development of a predictive score for mortality at 3- and 12-month after discharge from an acute geriatric unit as a trigger for advanced care planning. J Gerontol A Biol Sci Med Sci. 2021;doi: 10.1093/gerona/glab217.
Deschasse, G., Bloch, F., Drumez, E., Charpentier, A., Visade, F., Delecluse, C., Loggia, G., Lescure, P., Attier-Żmudka, J., Bloch, J., Gaxatte, C., Van Den Berghe, W., Puisieux, F., & Beuscart, J. B. (2021). Development of a predictive score for mortality at 3- and 12-month after discharge from an acute geriatric unit as a trigger for advanced care planning. The journals of gerontology. Series A, Biological sciences and medical sciences, . https://doi.org/10.1093/gerona/glab217
Deschasse, Guillaume, et al. "Development of a predictive score for mortality at 3- and 12-month after discharge from an acute geriatric unit as a trigger for advanced care planning." The journals of gerontology. Series A, Biological sciences and medical sciences vol. (2021). doi: https://doi.org/10.1093/gerona/glab217
Deschasse G, Bloch F, Drumez E, Charpentier A, Visade F, Delecluse C, Loggia G, Lescure P, Attier-Żmudka J, Bloch J, Gaxatte C, Van Den Berghe W, Puisieux F, Beuscart JB. Development of a predictive score for mortality at 3- and 12-month after discharge from an acute geriatric unit as a trigger for advanced care planning. J Gerontol A Biol Sci Med Sci. 2021 Aug 10; doi: 10.1093/gerona/glab217. Epub 2021 Aug 10. PMID: 34375411.
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Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later.

Clinical epigenetics

Jacobs A, Güiza F, Verlinden I, Dulfer K, Garcia Guerra G, Joosten K, Verbruggen SC, Vanhorebeek I, Van den Berghe G.
PMID: 34315515
Clin Epigenetics. 2021 Jul 27;13(1):146. doi: 10.1186/s13148-021-01124-3.

BACKGROUND: The PEPaNIC multicenter randomized controlled trial (RCT) has shown that early administration of supplemental parenteral nutrition (early-PN) as compared with withholding PN for 1 week (late-PN) induced long-term internalizing, externalizing and total emotional/behavioral problems in critically ill children,...

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Jacobs A, Güiza F, Verlinden I, et al. Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later. Clin Epigenetics. 2021;13(1):146doi: 10.1186/s13148-021-01124-3.
Jacobs, A., Güiza, F., Verlinden, I., Dulfer, K., Garcia Guerra, G., Joosten, K., Verbruggen, S. C., Vanhorebeek, I., & Van den Berghe, G. (2021). Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later. Clinical epigenetics, 13(1), 146. https://doi.org/10.1186/s13148-021-01124-3
Jacobs, An, et al. "Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later." Clinical epigenetics vol. 13,1 (2021): 146. doi: https://doi.org/10.1186/s13148-021-01124-3
Jacobs A, Güiza F, Verlinden I, Dulfer K, Garcia Guerra G, Joosten K, Verbruggen SC, Vanhorebeek I, Van den Berghe G. Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later. Clin Epigenetics. 2021 Jul 27;13(1):146. doi: 10.1186/s13148-021-01124-3. PMID: 34315515; PMCID: PMC8314560.
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Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice.

International journal of molecular sciences

Van den Bergh G, De Moudt S, Van den Branden A, Neven E, Leysen H, Maudsley S, De Meyer GRY, D'Haese P, Verhulst A.
PMID: 34769044
Int J Mol Sci. 2021 Oct 27;22(21). doi: 10.3390/ijms222111615.

Arterial media calcification (AMC) is predominantly regulated by vascular smooth muscle cells (VSMCs), which transdifferentiate into pro-calcifying cells. In contrast, there is little evidence for endothelial cells playing a role in the disease. The current study investigates cellular functioning...

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Van den Bergh G, De Moudt S, Van den Branden A, et al. Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice. Int J Mol Sci. 2021;22(21)doi: 10.3390/ijms222111615.
Van den Bergh, G., De Moudt, S., Van den Branden, A., Neven, E., Leysen, H., Maudsley, S., De Meyer, G. R. Y., D'Haese, P., & Verhulst, A. (2021). Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice. International journal of molecular sciences, 22(21), . https://doi.org/10.3390/ijms222111615
Van den Bergh, Geoffrey, et al. "Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice." International journal of molecular sciences vol. 22,21 (2021). doi: https://doi.org/10.3390/ijms222111615
Van den Bergh G, De Moudt S, Van den Branden A, Neven E, Leysen H, Maudsley S, De Meyer GRY, D'Haese P, Verhulst A. Endothelial Contribution to Warfarin-Induced Arterial Media Calcification in Mice. Int J Mol Sci. 2021 Oct 27;22(21). doi: 10.3390/ijms222111615. PMID: 34769044; PMCID: PMC8583869.
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Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?.

Environment international

Vanhorebeek I, Malarvannan G, Güiza F, Poma G, Derese I, Wouters PJ, Joosten K, Verbruggen S, Jorens PG, Covaci A, Van den Berghe G.
PMID: 34739923
Environ Int. 2021 Nov 02;158:106962. doi: 10.1016/j.envint.2021.106962. Epub 2021 Nov 02.

BACKGROUND: Children who have been critically ill face long-term developmental impairments. Iatrogenic exposure to di(2-ethylhexyl)phthalate (DEHP), a plasticizer leaching from plastic indwelling medical devices used in the pediatric intensive care unit (PICU), has been associated with the pronounced attention...

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Vanhorebeek I, Malarvannan G, Güiza F, et al. Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?. Environ Int. 2021;158:106962doi: 10.1016/j.envint.2021.106962.
Vanhorebeek, I., Malarvannan, G., Güiza, F., Poma, G., Derese, I., Wouters, P. J., Joosten, K., Verbruggen, S., Jorens, P. G., Covaci, A., & Van den Berghe, G. (2021). Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?. Environment international, 158106962. https://doi.org/10.1016/j.envint.2021.106962
Vanhorebeek, Ilse, et al. "Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?." Environment international vol. 158 (2021): 106962. doi: https://doi.org/10.1016/j.envint.2021.106962
Vanhorebeek I, Malarvannan G, Güiza F, Poma G, Derese I, Wouters PJ, Joosten K, Verbruggen S, Jorens PG, Covaci A, Van den Berghe G. Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?. Environ Int. 2021 Nov 02;158:106962. doi: 10.1016/j.envint.2021.106962. Epub 2021 Nov 02. PMID: 34739923.
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Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?.

Environment international

Vanhorebeek I, Malarvannan G, Güiza F, Poma G, Derese I, Wouters PJ, Joosten K, Verbruggen S, Jorens PG, Covaci A, Van den Berghe G.
PMID: 34739923
Environ Int. 2022 Jan;158:106962. doi: 10.1016/j.envint.2021.106962. Epub 2021 Nov 02.

BACKGROUND: Children who have been critically ill face long-term developmental impairments. Iatrogenic exposure to di(2-ethylhexyl)phthalate (DEHP), a plasticizer leaching from plastic indwelling medical devices used in the pediatric intensive care unit (PICU), has been associated with the pronounced attention...

Cite
Vanhorebeek I, Malarvannan G, Güiza F, et al. Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?. Environ Int. 2021;158:106962doi: 10.1016/j.envint.2021.106962.
Vanhorebeek, I., Malarvannan, G., Güiza, F., Poma, G., Derese, I., Wouters, P. J., Joosten, K., Verbruggen, S., Jorens, P. G., Covaci, A., & Van den Berghe, G. (2022). Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?. Environment international, 158106962. https://doi.org/10.1016/j.envint.2021.106962
Vanhorebeek, Ilse, et al. "Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?." Environment international vol. 158 (2022): 106962. doi: https://doi.org/10.1016/j.envint.2021.106962
Vanhorebeek I, Malarvannan G, Güiza F, Poma G, Derese I, Wouters PJ, Joosten K, Verbruggen S, Jorens PG, Covaci A, Van den Berghe G. Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?. Environ Int. 2022 Jan;158:106962. doi: 10.1016/j.envint.2021.106962. Epub 2021 Nov 02. PMID: 34739923.
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Tuning the properties of porous chitosan: Aerogels and cryogels.

International journal of biological macromolecules

Chartier C, Buwalda S, Van Den Berghe H, Nottelet B, Budtova T.
PMID: 35033531
Int J Biol Macromol. 2022 Jan 13; doi: 10.1016/j.ijbiomac.2022.01.042. Epub 2022 Jan 13.

Highly porous chitosan-based materials were prepared via dissolution, non-solvent induced phase separation and drying using different methods. The goal was to tune the morphology and properties of chitosan porous materials by varying process parameters. Chitosan concentration, concentration of sodium...

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Chartier C, Buwalda S, Van Den Berghe H, et al. Tuning the properties of porous chitosan: Aerogels and cryogels. Int J Biol Macromol. 2022;doi: 10.1016/j.ijbiomac.2022.01.042.
Chartier, C., Buwalda, S., Van Den Berghe, H., Nottelet, B., & Budtova, T. (2022). Tuning the properties of porous chitosan: Aerogels and cryogels. International journal of biological macromolecules, . https://doi.org/10.1016/j.ijbiomac.2022.01.042
Chartier, Coraline, et al. "Tuning the properties of porous chitosan: Aerogels and cryogels." International journal of biological macromolecules vol. (2022). doi: https://doi.org/10.1016/j.ijbiomac.2022.01.042
Chartier C, Buwalda S, Van Den Berghe H, Nottelet B, Budtova T. Tuning the properties of porous chitosan: Aerogels and cryogels. Int J Biol Macromol. 2022 Jan 13; doi: 10.1016/j.ijbiomac.2022.01.042. Epub 2022 Jan 13. PMID: 35033531.
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A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice.

Critical care (London, England)

Preiser JC, Arabi YM, Berger MM, Casaer M, McClave S, Montejo-González JC, Peake S, Reintam Blaser A, Van den Berghe G, van Zanten A, Wernerman J, Wischmeyer P.
PMID: 34906215
Crit Care. 2021 Dec 14;25(1):424. doi: 10.1186/s13054-021-03847-4.

The preferential use of the oral/enteral route in critically ill patients over gut rest is uniformly recommended and applied. This article provides practical guidance on enteral nutrition in compliance with recent American and European guidelines. Low-dose enteral nutrition can...

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Preiser JC, Arabi YM, Berger MM, et al. A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice. Crit Care. 2021;25(1):424doi: 10.1186/s13054-021-03847-4.
Preiser, J. C., Arabi, Y. M., Berger, M. M., Casaer, M., McClave, S., Montejo-González, J. C., Peake, S., Reintam Blaser, A., Van den Berghe, G., van Zanten, A., Wernerman, J., & Wischmeyer, P. (2021). A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice. Critical care (London, England), 25(1), 424. https://doi.org/10.1186/s13054-021-03847-4
Preiser, Jean-Charles, et al. "A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice." Critical care (London, England) vol. 25,1 (2021): 424. doi: https://doi.org/10.1186/s13054-021-03847-4
Preiser JC, Arabi YM, Berger MM, Casaer M, McClave S, Montejo-González JC, Peake S, Reintam Blaser A, Van den Berghe G, van Zanten A, Wernerman J, Wischmeyer P. A guide to enteral nutrition in intensive care units: 10 expert tips for the daily practice. Crit Care. 2021 Dec 14;25(1):424. doi: 10.1186/s13054-021-03847-4. PMID: 34906215.
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Tissue Exposure does not Explain Non-Response in Ulcerative Colitis Patients with Adequate Serum Vedolizumab Concentrations.

Journal of Crohn's & colitis

Van den Berghe N, Verstockt B, Gils A, Sabino J, Ferrante M, Vermeire S, Declerck P, Thomas D.
PMID: 33245363
J Crohns Colitis. 2021 Jun 22;15(6):988-993. doi: 10.1093/ecco-jcc/jjaa239.

BACKGROUND AND AIMS: Some patients with ulcerative colitis [UC] do not respond to vedolizumab treatment despite adequate drug exposure in serum. This study aimed to investigate vedolizumab in tissue and questioned whether insufficient tissue exposure could explain non-response in...

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Van den Berghe N, Verstockt B, Gils A, et al. Tissue Exposure does not Explain Non-Response in Ulcerative Colitis Patients with Adequate Serum Vedolizumab Concentrations. J Crohns Colitis. 2021;15(6):988-993doi: 10.1093/ecco-jcc/jjaa239.
Van den Berghe, N., Verstockt, B., Gils, A., Sabino, J., Ferrante, M., Vermeire, S., Declerck, P., & Thomas, D. (2021). Tissue Exposure does not Explain Non-Response in Ulcerative Colitis Patients with Adequate Serum Vedolizumab Concentrations. Journal of Crohn's & colitis, 15(6), 988-993. https://doi.org/10.1093/ecco-jcc/jjaa239
Van den Berghe, Nathalie, et al. "Tissue Exposure does not Explain Non-Response in Ulcerative Colitis Patients with Adequate Serum Vedolizumab Concentrations." Journal of Crohn's & colitis vol. 15,6 (2021): 988-993. doi: https://doi.org/10.1093/ecco-jcc/jjaa239
Van den Berghe N, Verstockt B, Gils A, Sabino J, Ferrante M, Vermeire S, Declerck P, Thomas D. Tissue Exposure does not Explain Non-Response in Ulcerative Colitis Patients with Adequate Serum Vedolizumab Concentrations. J Crohns Colitis. 2021 Jun 22;15(6):988-993. doi: 10.1093/ecco-jcc/jjaa239. PMID: 33245363.
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Higher drug exposure during the first 24 weeks of ustekinumab treatment is associated with endoscopic remission in Crohn's disease.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Van den Berghe N, Verstockt B, Vermeire S, Thomas D, Declerck P.
PMID: 34942369
Clin Gastroenterol Hepatol. 2021 Dec 20; doi: 10.1016/j.cgh.2021.12.020. Epub 2021 Dec 20.

No abstract available.

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Van den Berghe N, Verstockt B, Vermeire S, et al. Higher drug exposure during the first 24 weeks of ustekinumab treatment is associated with endoscopic remission in Crohn's disease. Clin Gastroenterol Hepatol. 2021;doi: 10.1016/j.cgh.2021.12.020.
Van den Berghe, N., Verstockt, B., Vermeire, S., Thomas, D., & Declerck, P. (2021). Higher drug exposure during the first 24 weeks of ustekinumab treatment is associated with endoscopic remission in Crohn's disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, . https://doi.org/10.1016/j.cgh.2021.12.020
Van den Berghe, Nathalie, et al. "Higher drug exposure during the first 24 weeks of ustekinumab treatment is associated with endoscopic remission in Crohn's disease." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association vol. (2021). doi: https://doi.org/10.1016/j.cgh.2021.12.020
Van den Berghe N, Verstockt B, Vermeire S, Thomas D, Declerck P. Higher drug exposure during the first 24 weeks of ustekinumab treatment is associated with endoscopic remission in Crohn's disease. Clin Gastroenterol Hepatol. 2021 Dec 20; doi: 10.1016/j.cgh.2021.12.020. Epub 2021 Dec 20. PMID: 34942369.
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Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?.

Critical care (London, England)

Langouche L, Van den Berghe G, Gunst J.
PMID: 34920750
Crit Care. 2021 Dec 17;25(1):437. doi: 10.1186/s13054-021-03861-6.

No abstract available.

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Langouche L, Van den Berghe G, Gunst J. Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?. Crit Care. 2021;25(1):437doi: 10.1186/s13054-021-03861-6.
Langouche, L., Van den Berghe, G., & Gunst, J. (2021). Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?. Critical care (London, England), 25(1), 437. https://doi.org/10.1186/s13054-021-03861-6
Langouche, Lies, et al. "Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?." Critical care (London, England) vol. 25,1 (2021): 437. doi: https://doi.org/10.1186/s13054-021-03861-6
Langouche L, Van den Berghe G, Gunst J. Hyperglycemia and insulin resistance in COVID-19 versus non-COVID critical illness: Are they really different?. Crit Care. 2021 Dec 17;25(1):437. doi: 10.1186/s13054-021-03861-6. PMID: 34920750.
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Long-Term Outcomes of the Minimally Invasive Ponto Surgery vs. Linear Incision Technique With Soft Tissue Preservation for Installation of Percutaneous Bone Conduction Devices.

Frontiers in neurology

Strijbos RM, Straatman LV, Calon TGA, Johansson ML, de Bruijn AJG, van den Berge H, Wagenaar M, Eichhorn E, Janssen M, Jonhede S, van Tongeren J, Holmberg M, Stokroos R.
PMID: 33716934
Front Neurol. 2021 Feb 24;12:632987. doi: 10.3389/fneur.2021.632987. eCollection 2021.

No abstract available.

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Strijbos RM, Straatman LV, Calon TGA, et al. Long-Term Outcomes of the Minimally Invasive Ponto Surgery vs. Linear Incision Technique With Soft Tissue Preservation for Installation of Percutaneous Bone Conduction Devices. Front Neurol. 2021;12:632987doi: 10.3389/fneur.2021.632987.
Strijbos, R. M., Straatman, L. V., Calon, T. G. A., Johansson, M. L., de Bruijn, A. J. G., van den Berge, H., Wagenaar, M., Eichhorn, E., Janssen, M., Jonhede, S., van Tongeren, J., Holmberg, M., & Stokroos, R. (2021). Long-Term Outcomes of the Minimally Invasive Ponto Surgery vs. Linear Incision Technique With Soft Tissue Preservation for Installation of Percutaneous Bone Conduction Devices. Frontiers in neurology, 12632987. https://doi.org/10.3389/fneur.2021.632987
Strijbos, Ruben M, et al. "Long-Term Outcomes of the Minimally Invasive Ponto Surgery vs. Linear Incision Technique With Soft Tissue Preservation for Installation of Percutaneous Bone Conduction Devices." Frontiers in neurology vol. 12 (2021): 632987. doi: https://doi.org/10.3389/fneur.2021.632987
Strijbos RM, Straatman LV, Calon TGA, Johansson ML, de Bruijn AJG, van den Berge H, Wagenaar M, Eichhorn E, Janssen M, Jonhede S, van Tongeren J, Holmberg M, Stokroos R. Long-Term Outcomes of the Minimally Invasive Ponto Surgery vs. Linear Incision Technique With Soft Tissue Preservation for Installation of Percutaneous Bone Conduction Devices. Front Neurol. 2021 Feb 24;12:632987. doi: 10.3389/fneur.2021.632987. eCollection 2021. PMID: 33716934; PMCID: PMC7945693.
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PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells.

Cancer letters

Chadelle L, Liu J, Choesmel-Cadamuro V, Karginov AV, Froment C, Burlet-Schiltz O, Gandarillas S, Barreira Y, Segura C, Van Den Berghe L, Czaplicki G, Van Acker N, Dalenc F, Franchet C, Hahn KM, Wang X, Belguise K.
PMID: 34826547
Cancer Lett. 2021 Nov 23;526:112-130. doi: 10.1016/j.canlet.2021.11.026. Epub 2021 Nov 23.

The cytoskeleton and cell-matrix adhesions constitute a dynamic network that controls cellular behavior during development and cancer. The Focal Adhesion Kinase (FAK) is a central actor of these cell dynamics, promoting cell-matrix adhesion turnover and active membrane fluctuations. However,...

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Chadelle L, Liu J, Choesmel-Cadamuro V, et al. PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells. Cancer Lett. 2021;526:112-130doi: 10.1016/j.canlet.2021.11.026.
Chadelle, L., Liu, J., Choesmel-Cadamuro, V., Karginov, A. V., Froment, C., Burlet-Schiltz, O., Gandarillas, S., Barreira, Y., Segura, C., Van Den Berghe, L., Czaplicki, G., Van Acker, N., Dalenc, F., Franchet, C., Hahn, K. M., Wang, X., & Belguise, K. (2021). PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells. Cancer letters, 526112-130. https://doi.org/10.1016/j.canlet.2021.11.026
Chadelle, Lucie, et al. "PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells." Cancer letters vol. 526 (2021): 112-130. doi: https://doi.org/10.1016/j.canlet.2021.11.026
Chadelle L, Liu J, Choesmel-Cadamuro V, Karginov AV, Froment C, Burlet-Schiltz O, Gandarillas S, Barreira Y, Segura C, Van Den Berghe L, Czaplicki G, Van Acker N, Dalenc F, Franchet C, Hahn KM, Wang X, Belguise K. PKCθ-mediated serine/threonine phosphorylations of FAK govern adhesion and protrusion dynamics within the lamellipodia of migrating breast cancer cells. Cancer Lett. 2021 Nov 23;526:112-130. doi: 10.1016/j.canlet.2021.11.026. Epub 2021 Nov 23. PMID: 34826547.
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