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Showing 13 to 24 of 177 entries
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The genomics of heart failure: design and rationale of the HERMES consortium.

ESC heart failure

Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Mälarstig A, Andersson C, Verweij N, Holmes MV, Ärnlöv J, Svensson P, Hemingway H, Sallah N, Almgren P, Aragam KG, Asselin G, Backman JD, Biggs ML, Bloom HL, Boersma E, Brandimarto J, Brown MR, Brunner-La Rocca HP, Carey DJ, Chaffin MD, Chasman DI, Chazara O, Chen X, Chen X, Chung JH, Chutkow W, Cleland JGF, Cook JP, de Denus S, Dehghan A, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Engström G, Esko T, Fatemifar G, Felix SB, Finan C, Ford I, Fougerousse F, Fouodjio R, Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gui H, Gutmann R, Haggerty CM, van der Harst P, Hedman ÅK, Helgadottir A, Hillege H, Hyde CL, Jacob J, Jukema JW, Kamanu F, Kardys I, Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Kraus B, Kuchenbaecker K, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J, Magnusson P, Mahajan A, Mann D, Margulies KB, Marston NA, März W, McMurray JJV, Melander O, Melloni G, Mordi IR, Morley MP, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP, Newton-Cheh C, Niessner A, Niiranen T, Nowak C, O'Donoghue ML, Owens AT, Palmer CNA, Paré G, Perola M, Perreault LL, Portilla-Fernandez E, Psaty BM, Rice KM, Ridker PM, Romaine SPR, Roselli C, Rotter JI, Ruff CT, Sabatine MS, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT, Smith NL, Stefansson K, Stender S, Stott DJ, Sveinbjörnsson G, Tammesoo ML, Tardif JC, Taylor KD, Teder-Laving M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-Pedersen C, Trompet S, Tuckwell D, Tyl B, Uitterlinden AG, Vaura F, Veluchamy A, Visscher PM, Völker U, Voors AA, Wang X, Wareham NJ, Weeke PE, Weiss R, White HD, Wiggins KL, Xing H, Yang J, Yang Y, Yerges-Armstrong LM, Yu B, Zannad F, Zhao F, Wilk JB, Holm H, Sattar N, Lubitz SA, Lanfear DE, Shah S, Dunn ME, Wells QS, Asselbergs FW, Hingorani AD, Dubé MP, Samani NJ, Lang CC, Cappola TP, Ellinor PT, Vasan RS, Smith JG.
PMID: 34480422
ESC Heart Fail. 2021 Sep 03; doi: 10.1002/ehf2.13517. Epub 2021 Sep 03.

AIMS: The HERMES (HEart failure Molecular Epidemiology for Therapeutic targetS) consortium aims to identify the genomic and molecular basis of heart failure.METHODS AND RESULTS: The consortium currently includes 51 studies from 11 countries, including 68 157 heart failure cases...

The role of action potential changes in depolarization-induced failure of excitation contraction coupling in mouse skeletal muscle.

eLife

Wang X, Nawaz M, DuPont C, Myers JH, Burke SR, Bannister RA, Foy BD, Voss AA, Rich MM.
PMID: 34985413
Elife. 2022 Jan 05;11. doi: 10.7554/eLife.71588.

Excitation-contraction coupling (ECC) is the process by which electrical excitation of muscle is converted into force generation. Depolarization of skeletal muscle resting potential contributes to failure of ECC in diseases such as periodic paralysis, intensive care unit acquired weakness...

Atrial function in paroxysmal AF patients with and without heart failure with preserved ejection fraction: Data from the AF-RISK study.

American heart journal

Artola Arita V, Santema BT, De With RR, Nguyen BO, Linz D, Schotten U, Van Gelder IC, Crijns HJ, Voors AA, Rienstra M.
PMID: 34688651
Am Heart J. 2021 Oct 21;244:36-41. doi: 10.1016/j.ahj.2021.10.183. Epub 2021 Oct 21.

Atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) are 2 cardiovascular conditions that often coexist. Strain phases of both the left and right atria are more impaired in paroxysmal AF patients with HFpEF than those without...

Inheritance of DNA methylation differences in the mangrove Rhizophora mangle.

Evolution & development

Mounger J, Boquete MT, Schmid MW, Granado R, Robertson MH, Voors SA, Langanke KL, Alvarez M, Wagemaker CAM, Schrey AW, Fox GA, Lewis DB, Lira CF, Richards CL.
PMID: 34382741
Evol Dev. 2021 Jul;23(4):351-374. doi: 10.1111/ede.12388. Epub 2021 Aug 12.

The capacity to respond to environmental challenges ultimately relies on phenotypic variation which manifests from complex interactions of genetic and nongenetic mechanisms through development. While we know something about genetic variation and structure of many species of conservation importance,...

Sodium-glucose co-transporter 2 inhibitors as an early, first-line therapy in patients with heart failure and reduced ejection fraction.

European journal of heart failure

Tomasoni D, Fonarow GC, Adamo M, Anker SD, Butler J, Coats AJS, Filippatos G, Greene SJ, McDonagh TA, Ponikowski P, Rosano G, Seferovic P, Vaduganathan M, Voors AA, Metra M.
PMID: 34894038
Eur J Heart Fail. 2021 Dec 10; doi: 10.1002/ejhf.2397. Epub 2021 Dec 10.

Sodium-glucose co-transporter 2 (SGLT2) inhibitors have recently been recommended as a foundational therapy for patients with heart failure (HF) and reduced ejection fraction (HFrEF) because of their favourable effects on mortality, clinical events and quality of life. While clinical...

Self-reported subjective cognitive decline is associated with global cognition in a community sample of Latinos/as/x living in the United States.

Journal of clinical and experimental neuropsychology

Nakhla MZ, Cohen L, Salmon DP, Smirnov DS, Marquine MJ, Moore AA, Schiehser DM, Zlatar ZZ.
PMID: 34709141
J Clin Exp Neuropsychol. 2021 Sep;43(7):663-676. doi: 10.1080/13803395.2021.1989381. Epub 2021 Oct 28.

INTRODUCTION: Although subjective cognitive decline (SCD) may be an early risk marker of Alzheimer's Disease (AD), research on SCD among Hispanics/Latinos/as/x (henceforth Latinos/as) living in the U.S. is lacking. We investigated if the cross-sectional relationship of self-reported SCD with...

Natriuresis guided therapy in acute heart failure: rationale and design of the Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart Failure (PUSH-AHF) trial.

European journal of heart failure

Ter Maaten JM, Beldhuis IE, van der Meer P, Krikken JA, Coster JE, Nieuwland W, van Veldhuisen DJ, Voors AA, Damman K.
PMID: 34791756
Eur J Heart Fail. 2021 Nov 17; doi: 10.1002/ejhf.2385. Epub 2021 Nov 17.

AIMS: Insufficient diuretic response frequently occurs in patients admitted for acute heart failure (HF) and is associated with worse clinical outcomes. Recent studies have shown that measuring natriuresis early after hospital admission could reliably identify patients with a poor...

Sex-Specific Clinical Outcomes of the PACT-HF Randomized Trial.

Circulation. Heart failure

Van Spall HGC, DeFilippis EM, Lee SF, Oz UE, Perez R, Healey JS, Allen LA, Voors AA, Ko DT, Thabane L, Connolly SJ.
PMID: 34711072
Circ Heart Fail. 2021 Nov;14(11):e008548. doi: 10.1161/CIRCHEARTFAILURE.121.008548. Epub 2021 Oct 29.

BACKGROUND: Transitional care may have different effects in males and females hospitalized for heart failure. We assessed the sex-specific effects of a transitional care model on clinical outcomes following hospitalization for heart failure.METHODS: In this stepped-wedge cluster randomized trial...

Atrial function in paroxysmal AF patients with and without heart failure with preserved ejection fraction: Data from the AF-RISK study.

American heart journal

Artola Arita V, Santema BT, De With RR, Nguyen BO, Linz D, Schotten U, Van Gelder IC, Crijns HJ, Voors AA, Rienstra M.
PMID: 34688651
Am Heart J. 2021 Oct 21;244:36-41. doi: 10.1016/j.ahj.2021.10.183. Epub 2021 Oct 21.

Atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) are 2 cardiovascular conditions that often coexist. Strain phases of both the left and right atria are more impaired in paroxysmal AF patients with HFpEF than those without...

Acetylcholine receptor subunit expression in Huntington's disease mouse muscle.

Biochemistry and biophysics reports

Simpson B, Rich MM, Voss AA, Talmadge RJ.
PMID: 34926838
Biochem Biophys Rep. 2021 Dec 05;28:101182. doi: 10.1016/j.bbrep.2021.101182. eCollection 2021 Dec.

Huntington's disease (HD) causes neurological impairments, as well as muscle dysfunction, including smaller neuromuscular junctions (NMJs). This study assessed the expression levels of the subunits of the nicotinic acetylcholine receptor (nAChR) in muscles of the R6/2 mouse model of...

Atrial function in paroxysmal AF patients with and without heart failure with preserved ejection fraction: Data from the AF-RISK study.

American heart journal

Artola Arita V, Santema BT, De With RR, Nguyen BO, Linz D, Schotten U, Van Gelder IC, Crijns HJ, Voors AA, Rienstra M.
PMID: 34688651
Am Heart J. 2021 Oct 21;244:36-41. doi: 10.1016/j.ahj.2021.10.183. Epub 2021 Oct 21.

Atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) are 2 cardiovascular conditions that often coexist. Strain phases of both the left and right atria are more impaired in paroxysmal AF patients with HFpEF than those without...

ISBER 2021 Annual Meeting.

Biopreservation and biobanking

Moors AJ, Otto B, Garcia DL, Henderson MK.
PMID: 34415783
Biopreserv Biobank. 2021 Oct;19(5):457-458. doi: 10.1089/bio.2021.29092.mjh. Epub 2021 Aug 19.

No abstract available.

Showing 13 to 24 of 177 entries